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UJI AKTIVITAS ANTIFUNGI BAKTERI ASAM LAKTAT ASAL DADIH TERHADAP Aspergillus flavus Olvaria Misfa; Viola Anggraini Asrizal; Eliya Mursyida; Uly Astuti Siregar
Collaborative Medical Journal Vol 6 No 1 (2023): Januari
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/cmj.v6i1.3254

Abstract

Primary gastrointestinal aspergillosis (AGP) is an inflammation of the gastrointestinal tract from the duodenum to the rectum. Aspergillus flavus (A. flavus) is one of the fungi that causes aspergillosis. This infection occurs due to aflatoxin from A. flavus which can cause damage to the gastric mucosa. The use of antifungals for long-term treatment can cause toxicity effects and also resistance, so alternative treatments are needed. Dadih is a fermented product of buffalo milk which contains lactic acid bacteria (LAB). Lactic acid bacteria produce acetic acid, lactic acid, and bacteriocin which can inhibit the growth of the fungus A. flavus. LAB species capable of suppressing the growth of A. flavus were Lactococcus lactis, Lactobacillus casei subsp. pseudoplantarum and Lactobacillus plantarum, and Lactobacillus brevis. To determine and analyze the antifungal activity of lactic acid bacteria from curd against Aspergillus flavus. This study used a post test-only design with a control group. The sample used was LAB isolate from curd, while the test fungus used was A. flavus. This study begins with rejuvenation of LAB isolates, then classification of LAB and pathogens, as well as inhibition test using the well diffusion method. The data obtained were analyzed using One-Way ANOVA test and Bonferroni Post hoc test.: LAB isolates from curd were Gram-positive bacteria in the form of bacilli and cocobasil, with negative catalse test results. The average diameter of the inhibition zones of LAB 1, LAB 2, and LAB against A. flavus were 8.55mm, 10.23mm, and 6.20mm. The results of the ANOVA test showed that there was a significant difference between the three LABs. The results of the Bonferron Post hoc test showed that there was a significant difference between LAB 2 isolates and positive controls against LAB 3. Meanwhile, there was no significant difference between LAB 2 and BAL 3 isolates against LAB 1 isolates. LAB isolate from curd was able to inhibit the growth of the fungus A. flavus.
HUBUNGAN MOTIVASI BELAJAR TERHADAP SELF DIRECTED LEARNING READINESS (SDLR) PADA MAHASISWA FAKULTAS KEDOKTERAN UNIVERSITAS ABDURRAB PEKANBARU Olvaria Misfa; Sandra Putri Yulita; Huda Marlina Wati; Riski Dwi Utami
Collaborative Medical Journal Vol 7 No 3 (2024): September 2024
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/cmj.v7i3.5798

Abstract

Self directed learning readiness (SDLR) is the readiness of students to learn independently. SDLR implements learning that involves a self-view that focuses on overall independence. In students with low SDLR, it is caused by a lack of motivation in learning in students and ignorance of students in learning independently. The Faculty of Medicine, Abdurrab University is one of the Faculties of Medicine that implements a learning system with the concept of student-centered learning with a problem-based learning approach. The use of PBL with a student-centered learning system at the Faculty of Medicine, Abdurrab University encourages students to have SDLR as a support for the student learning process so that they get maximum results. Based on the preliminary research that has been carried out from the results of the final exam of the module, there are no students who pass the final exam of the module. The purpose of this study is to find out whether there is a relationship between learning motivation and self-directed learning readiness (SDLR) in students of the Faculty of Medicine, Abdurrab University, Pekanbaru. Methods This study uses a type of analytical observational research with a cross sectional method. Sampling technique was carried out by stratified random sampling technique on students of the Faculty of Medicine, Abdurrab University at the academic stage. Data analysis uses the Spearman correlation test. The results of the correlation between learning motivation and self-directed learning readiness (SDLR) in students of the Faculty of Medicine, Abdurrab University (p-value <0.05) with a correlation value of 0.459 with a moderate correlation strength were obtained.
HUBUNGAN MANAJEMEN WAKTU DENGAN KESIAPAN BELAJAR MANDIRI (SELF DIRECTED LEARNING READINESS) PADA MAHASISWA PROGRAM STUDI PENDIDIKAN DOKTER FAKULTAS KEDOKTERAN UNIVERSITAS ABDURRAB Riski Dwi Utami; Ranti Novita Sari; Huda Marlina Wati; Ratih Ayuningtiyas; Olvaria Misfa
Collaborative Medical Journal Vol 8 No 2 (2025): Mei 2025
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/cmj.v8i2.6373

Abstract

Problem-Based Learning (PBL) is a learning approach that puts students at the center and exposes students to unsolved problems. One of the important components that is trained and useful in PBL is Self-Directed Learning (SDL) and the important factors in the implementation of the SDL is Self-Directed Learning Readiness (SDLR). Time management is an aspect of self-management that can be assessed in the SDLR. Time management is a way to see how students manage their time to complete tasks and activities well. This study aimed to analyze the relationship between time management and self-directed learning readiness in students in the Medical Education Study Program, Faculty of Medicine, Abdurrab University. This study is observational analytical with a cross-sectional design. The sampling technique was used by stratified random sampling. The total sample in this study is 206. Data analysis uses the spearman rank correlation test.The group of students who have the most high-category time management is in the class of 2020. SDLR is highest in the class of 2022. The correlation test showed a value of p <0.05. The spearman correlation value is 0.642 which means that there is a correlation between time management and the level of self-directed learning readiness. There is a significant relationship between time management and the level of self-directed learning readiness in students in the Medical Education Study Program, Faculty of Medicine, Abdurrab University.
EFEKTIVITAS GEL EKSTRAK DAUN BELIMBING WULUH (Averrhoa bilimbi L.) TERHADAP PENYEMBUHAN LUKA SAYAT PADA TIKUS PUTIH YANG DIINFEKSI Staphylococcus aureus Riski Dwi Utami; Andre Andre; Mahendra Mahendra; Olvaria Misfa
Collaborative Medical Journal Vol 8 No 3 (2025): September 2025
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/cmj.v8i3.7671

Abstract

In Indonesia, the prevalence of cut wounds is 9.2%. Healing is affected by the wound’s length, depth, and infection, with Staphylococcus aureus being a common infecting bacterium. Starfruit leaf extract, in gel form, offers benefits like ease of application, no residue, and quick drying. This study aimed to assess the effectiveness of starfruit leaf extract gel in healing Staphylococcus aureus-infected cuts in white mice, using a true experimental design with 20 mice divided into four groups: positive control (povidone iodine), negative control (gel base), and two treatment groups with 6% and 12% starfruit leaf extract gels. Bivariate analysis used the one way ANOVA test and continued with the Post Hoc Bonferroni test. The study found the smallest incision length on day 3 was 6% starfruit leaf extract gel group with a mean of 12,505 mm2, while on days 7, 14 and 21 it was group positive control with a mean of 11,867 mm2, 1,367 mm2, 0,000 mm2. The results of the One Way Anova test on days 3, 7, 14 and 21 have a p value < 0.05, meaning there is a significant difference in wound healing between groups. Starfruit leaf extract gel is effective in healing cut wounds in white mice infected with S.aureus. Starfruit leaf extract gel with a concentration of 12% is more effective in healing long cuts infected with S.aureus than a concentration of 6%.