Article Per Year (5 Year)
p-Index From 2020 - 2025
1.564
P-Index
This Author published in this journals
All Journal Majalah Kedokteran Nusantara The Journal Of Medical School Sumatera Medical Journal Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Journal of Public Health and Pharmacy Grimsa Journal of Science Engineering and Technology Ophthalmologica Indonesiana
Sari, Masitha Dewi
Department Of Ophtalmology, Medical Faculty, North Sumatera University, Medan, 20222, Indonesia
Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Physics Public Health

Published : 10 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : Grimsa Journal of Science Engineering and Technology

 1 
Hippobroma longiflora L Leaves as a Natural Inhibitor of Cataract Progression: A Comprehensive Study Integrating Ethanol Extract, HPLC, and Molecular Docking Approaches Eva Imelda; Ulfa Fitria; Ulmiza Putri Mutia; Syahrul Syahrul; Masitha Dewi Sari; Sarra Mutiara Adev; Alya Mutiara Adev; Zakiaturrahmi Zakiaturrahmi; Navneet Shamsundar Toshniwal
Grimsa Journal of Science Engineering and Technology Vol. 1 No. 2 (2023): December 2023
Publisher : Graha Primera Saintifika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61975/gjset.v1i2.10

Abstract

Cataract remains the highest preventable cause of blindness in the world. The H. longiflora plant (Hippobroma longiflora L) is a plant that has empirically been widely used to treat a variety of eye diseases including cataract. This plant has high antioxidant activity due to its high phenolic and flavonoid content. The H. longiflora plant was extracted using an ethanol solvent and its compound content was analyzed using GCMS and phytochemistry analysis. The extracts obtained were tested with TPC, TFC, antioxidants and quercetine compound with HPLC. From phytochemical and GCMS analysis, it was found that triterpenoid compounds were not found in the sample, and the compound 1-Isobutyl-2,5-dimethyl-4-phenyl-piperidin-4-ol was the most abundant (37.77%), as well as 4-Penten-1-ol, 5-phenyl-3-pperidino (1,30%) were the least abundant in the ethanol extract of the H. longiflora leaves extract. The total phenolic, flavonoid and HPLC results of quercetin were 139.21 mg GAE/g; 11.48 mg QE/G and 0.009 mg/G. Meanwhile, in an antioxidant activity test, it was found that the ethanol extract of the H. longiflora leaves has very strong antioxidants. This finding revealed the potential of ethanol extracts of H. longiflora leaves as a cataract inhibitor through its process as an antioxidant.
Hippobroma longiflora L Leaves as a Natural Inhibitor of Cataract Progression: A Comprehensive Study Integrating Ethanol Extract, HPLC, and Molecular Docking Approaches Imelda, Eva; Fitria, Ulfa; Mutia, Ulmiza Putri; Syahrul, Syahrul; Sari, Masitha Dewi; Adev, Sarra Mutiara; Adev, Alya Mutiara; Zakiaturrahmi, Zakiaturrahmi; Toshniwal, Navneet Shamsundar
Grimsa Journal of Science Engineering and Technology Vol. 1 No. 2 (2023): December 2023
Publisher : Graha Primera Saintifika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61975/gjset.v1i2.10

Abstract

Cataract remains the highest preventable cause of blindness in the world. The H. longiflora plant (Hippobroma longiflora L) is a plant that has empirically been widely used to treat a variety of eye diseases including cataract. This plant has high antioxidant activity due to its high phenolic and flavonoid content. The H. longiflora plant was extracted using an ethanol solvent and its compound content was analyzed using GCMS and phytochemistry analysis. The extracts obtained were tested with TPC, TFC, antioxidants and quercetine compound with HPLC. From phytochemical and GCMS analysis, it was found that triterpenoid compounds were not found in the sample, and the compound 1-Isobutyl-2,5-dimethyl-4-phenyl-piperidin-4-ol was the most abundant (37.77%), as well as 4-Penten-1-ol, 5-phenyl-3-pperidino (1,30%) were the least abundant in the ethanol extract of the H. longiflora leaves extract. The total phenolic, flavonoid and HPLC results of quercetin were 139.21 mg GAE/g; 11.48 mg QE/G and 0.009 mg/G. Meanwhile, in an antioxidant activity test, it was found that the ethanol extract of the H. longiflora leaves has very strong antioxidants. This finding revealed the potential of ethanol extracts of H. longiflora leaves as a cataract inhibitor through its process as an antioxidant.
Co-Authors Adev, Alya Mutiara Adev, Sarra Mutiara Alvin Rambe Alya Mutiara Adev Amra, Aryani Atiyatul Anggreiny Angie, Evelyn Aslim, D Sihotang Barii Hafidh Pramono Delfi Eva Imelda Felanda Ahsanu Nadia Felanda Ahsanu Nadia Fithria Aldy Fitria, Ulfa Imelda, Eva Kiking Ritarwan Malau, Tamara Betanya Muhammad Hendy Hasudungan Hutabarat Mutia, Ulmiza Putri Muzasti, Riri Andri Navneet Shamsundar Toshniwal Sarra Mutiara Adev Syahrul Syahrul Syahrul Syahrul Taufik Ashar Toshniwal, Navneet Shamsundar Ulfa Fitria Ulmiza Putri Mutia Zakiaturrahmi Zakiaturrahmi Zakiaturrahmi, Zakiaturrahmi