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All Journal JURNAL ILMIAH KESEHATAN SANDI HUSADA Jurnal Prima Medika Sains Prima JODS Open Access Indonesian Journal of Medical Reviews Bioscientia Medicina : Journal of Biomedicine and Translational Research Community Medicine and Education Journal Buletin Kedokteran dan Kesehatan Prima Tour Health Journal Jurnal Ilmiah Kesehatan Sandi Husada
Hutagalung, Mangatas Halomoan Parluhutan
Fakultas Kedokteran Gigi Universitas Prima Indonesia
Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health

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Comparison of bacang mango leaf extract concentrations (25%, 50%, and 75%) in inhibiting Streptococcus mutans in vitro Hutagalung, Mangatas Halomoan Parluhutan; Erawati, Suci; Lumbansiantar, Ruben Tutamana
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 2 (2025): September
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i2.7528

Abstract

Observations in Pancur Batu District, Deli Serdang Regency, revealed an abundant growth of Bacang mango trees (Mangifera foetida), yet their potential benefits remain underutilized by the local community. This study aimed to investigate and provide insight into the antibacterial properties of Bacang mango leaf extract. An experimental laboratory study was conducted using a randomized posttest-only control group design. The results demonstrated that Bacang mango leaf extract effectively inhibited the growth of Streptococcus mutans in vitro, surpassing the efficacy of 0.2% chlorhexidine digluconate used as a positive control. Measurement of the inhibition zone diameters indicated a proportional relationship between extract concentration and antibacterial efficacy. At 25% concentration, the mean inhibition zone diameter was 13.15 ± 0.49 mm. Increasing the concentration to 50% yielded a larger diameter of 15.75 ± 0.66 mm, while the highest antibacterial activity was observed at 75% concentration, with an inhibition zone diameter of 16.73 ± 0.55 mm. In comparison, the 0.2% chlorhexidine digluconate positive control produced an inhibition zone diameter of only 12.50 ± 0.26 mm. These findings suggest that Bacang mango leaf extract at 75% concentration is the most effective in inhibiting Streptococcus mutans growth. Its significantly greater inhibitory effect relative to lower concentrations and the positive control highlights its potential as a natural antibacterial agent.
Co-Authors Ainun, Nur Azizah Angeline Fransisca Panjaitan Beatrice Gabriela Dear Chandra Wijaya Cindy Denhara Wijaya Daulay, Agus Husein Dini Arta Lestari Dalimunthe Dini Arta Lestari Dalimunthe Doni Aldi Lumbantobing Fitwy Inka Teresha Silaban Hutajulu, Yohanes Idamawati Nababan Idamawati Nababan Juwita Isabella Siregar Kevin Imanuel Tarigan Laurencia Kasih Putri Hulu Lumbansiantar, Ruben Tutamana Maghfirah Muchtar Member Reni Purba Molek Molek Molek, Molek Muhammad Khusairi Muhammad Khusairi Nababan, Titus Imanuel Nainggolan, Serevina Rahmadani, Lydia Rajindervir Singh Salamon, Yuda Monang Sembiring, Bob Agustinus Sendyra Utama Siahaan, Jekson Martiar Sihotang, Ruth Wydia Wati Simanjuntak, Maestro Bina Utama Sinurat, Suryati Sonia Nduma Nola Padang Suci Erawati Suryati Sinurat Susiani Tarigan Tampubolon, Ruth Septianna Br. Tara Suryantika Tarigan, Leonardo Tarigan, Susiani Tia Safitri Welly Effendy Seba Yeggie Nugranti