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All Journal Medika Tadulako Syntax Literate: Jurnal Ilmiah Indonesia Farmasains : Jurnal Ilmiah Ilmu Kefarmasian JRST (Jurnal Riset Sains dan Teknologi) FITOFARMAKA: Jurnal Ilmiah Farmasi JFIOnline Poltekita : Jurnal Ilmu Kesehatan Jurnal Kefarmasian Indonesia Journal of Natural Product for Degenerative Diseases
Ros Sumarny
Department of Pharmacology, Faculty of Pharmacy Pancasila University Jakarta
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Education Engineering Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Potentially Inappropriate Medication (PIM) Prescribing According to Beers Criteria among Elderly Outpatients at Pasar Minggu Hospital, Jakarta Pebriani, Mala; Sumarny, Ros; Arozal, Wawaimuli; Eviarini, Prawitasari; Ismaya, Nurwulan Adi
Jurnal Kefarmasian Indonesia VOLUME 14, NUMBER 1, FEBRUARY 2024
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

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Abstract

Elderly patients generally have physiological changes that cause multipathological conditions, so they require several drugs to treat these conditions, it is necessary to evaluate the use of drugs to optimize the treatment of geriatric patients. Beers Criteria 2019 is a criteria that is commonly used to present Potentially Inappropriate Medication (PIM). This study aimed to examine the inaccuracy of prescription drugs in the elderly using Beer's criteria 2019. This research is an observational analytic study with a cross-sectional descriptive design. The Beer's 2019 criteria classify PIM into five categories. Data were taken retrospectively as many as 847 prescriptions met the inclusion criteria at the Pasar Minggu Hospital Outpatient Polyclinic. Data were analysed by Univariate and Bivariate. The results showed that from 847 prescriptions for geriatric patients, there are 160 prescriptions for geriatric patients who experienced PIM (18.89%). Percentage of PIM incidents by category; namely, category 1 was 29.17%, category 2 was 6.77%, category 3 was 44.79%, category 4 was 16.67%, and category 5 was 2.60%. The results of the analysis showed that there was a significant relationship between the number of drugs and Heart Failure and CAD with the incidence of PIM with a p value of 0.000 and 0.035. DM and Heart Failure are 2 diseases that significantly influence the incidence of PIM. This study concludes that the elderly are at risk for receiving potentially inappropriate medications.
Analysis of risk factors for recurrent stroke in stroke patients: Analisis Faktor Risiko Kejadian Stroke Berulang Pada Pasien Stroke Dwiyanti, Luvty S.L.; Abdillah, Syamsudin; Sumarny, Ros; Diandy, M. Ivan
JRST (Jurnal Riset Sains dan Teknologi) Volume 10 No. 1, March 2026: JRST
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/jrst.v10i1.26489

Abstract

Stroke is the second leading cause of death after heart disease. It is reported that annually, over 15 million people worldwide suffer a stroke, resulting in disability or death. Indonesia has the highest stroke mortality rate among countries in Southeast Asia. Within 30 days, the risk of recurrent stroke is very high, with one contributing factor being non-adherence to antiplatelet therapy for recurrent stroke prevention. This study aimed to analyze medication adherence and risk factors associated with recurrent stroke incidents. The research employed an observational analytic method with a case-control study design. The study sample consisted of recurrent stroke patients and post-stroke patients, with 65 patients in each group, recruited from the neurology polyclinic of "X" Hospital in Jakarta during the period of December 2024 to January 2025. Data were collected using questionnaires and the Hospital Management Information System (SIMRS). Bivariate analysis was conducted using the Chi-Square test, and multivariate analysis was performed using multiple logistic regression. The results indicated that the respondent characteristics in both groups were patients aged 18–64 years, male, unemployed, and with low income below the regional minimum wage. Bivariate analysis identified the following risk factors associated with recurrent stroke: medication adherence, physical activity, blood pressure levels, and triglyceride levels. Multivariate analysis. ABSTRAK (Bahasa Indonesia) Stroke merupakan penyebab kematian tertinggi kedua setelah penyakit jantung, Dilaporkan bahwa setiap tahun >15 juta orang diseluruh dunia menderita stroke yang mengalami disabilitas bahkan kematian. Indonesia merupakan Negara dengan angka kematian tertinggi pada penderita stroke di Asia Tenggara. Dalam waktu 30 hari, resiko stroke berulang sangat tinggi, Salah satu pemicunya adalah ketidakpatuhan terhadap terapi pencegahan stroke berulang dengan antiplatelet. Penelitian ini bertujuan untuk menganalisis kepatuhan penggunaan obat dan faktor risiko yang berhubungan dengan kejadian stroke berulang. Metode penelitian yang digunakan adalah observasional analitik dengan desain case control study. Sampel penelitian adalah pasien stroke berulang dan pasien pasca stroke dengan jumlah sampel masing – masing sebanyak 65 pasien di poli saraf Rumah sakit “X” Jakarta periode Desember 2024 – Januari 2025. Pengambilan data menggunakan kuesioner dan SIMRS (Sistem Manajemen Rumah Sakit). Analisis bivariat menggunakan Chi Square, analisis multivariat dengan regresi logistik berganda. Hasil penelitian menunjukkan bahwa karakteristik responden di kedua kelompok adalah pasien dengan usia 18 – 64 tahun, berjenis kelamin laki – laki, tidak bekerja dan memiliki pendapatan rendah di bawah UMR. Secara bivariat, diperoleh faktor risiko yang berhubungan dengan kejadian stroke berulang adalah kepatuhan penggunaan obat, aktivitas fisik, nilai tekanan darah dan nilai trigliserida. Hasil analisis multivariat, variabel yang paling dominan berhubungan dengan kejadian stroke berulang adalah nilai tekanan darah yang tidak terkontrol (OR 0.216 dengan CI 0.086-0.543) pasien dengan nilai tekanan darah yang tidak terkontrol memiliki risiko 4.6 kali mengalami kejadian stroke berulang dibandingkan dengan pasien yang mempunyai nilai tekanan darah terkontrol.    
Co-Authors . Syamsudin Arief, Ilham Atut Ruswita Dian Ratih Laksmitawati Diandy, M. Ivan Dwiyanti, Luvty S.L. Eviarini, Prawitasari Fernandez, Itha Hasan, Delina Indra Kusuma Kapuangan, Christopher Kiki Amelia, Kiki Komar, Hafid Kumalawati, July Kuncoro, Daviet Dwi Kurniawan, Affandi Larasinta, Nadia Musridharta, Eka Nurwulan Adi Ismaya Pebriani, Mala Pratama, Yori Chikita Putri, Arini Amalia Rachmani, Rum Rachmani, Rum Shirly Kumala Tomasoa, Edwin Ulya, Nurul Utukaman, Katharina Aditya Candra Wawaimuli Arozal Yati Sumiyati, Yati Zunnita, Oktaviana