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All Journal Jurnal Kimia Terapan Indonesia Mengabdi: Jurnal Hasil Kegiatan Bersama Masyarakat Jurnal Kesehatan Masyarakat Indonesia (JKMI) Vitalitas Medis : Jurnal Kesehatan Dan Kedokteran AS-SHIHA: JURNAL KESEHATAN
Novita Ariani
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Education Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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The Evaluation of Substrates and Trichoderma sp. Isolates for Cellulase Production Eka Triwahyuni; Yosi Aristiawan; Novita Ariani; Haznan Abimanyu; Trisanti Anindyawati
Jurnal Kimia Terapan Indonesia Vol 20, No 1 (2018)
Publisher : Research Center for Chemistry - LIPI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (650.106 KB) | DOI: 10.14203/jkti.v20i1.384

Abstract

AbstractAs higher interest was on the lignocellulose-based or second generation bioethanol production, the research was then more focused on the production of cellulase, especially on the domestic enzyme. Trichoderma sp. is considered as one of the most efficient producer of cellulase. This study was conducted to investigate the performance of Trichoderma sp. on a variety of substrates to produce cellulase. Three types of substrate variations and three types of Trichoderma sp. were used in this experiment. The substrate used were wheat bran, rice bran and oil palm empty fruit bunches (EFBs), whereas Trichoderma sp. isolates were encoded as T004, T051 and T063. Production of cellulase was made by solid fermentation for 7 days. The analysis of cellulase activity was done by National Renewable Energy Laboratory (NREL) method for filter paper assay. The results showed that the type of substrate affected the performance of Trichoderma sp. All types of fungus produced cellulase on wheat bran substrate with activity of 0.52 FPU /ml for T004, 0.23 FPU/ml for T051 and 0.27 FPU /ml for T063. With the rice bran substrate and EFBs, only T004 could produce cellulase and the enzyme activity analyzed were 0.08 FPU /ml and 0.008 FPU/ml respectively. Optimation of the buffer addition on enzyme extraction process produces the highest activity 0.85 FPU/mL for T004 with wheat bran substrate. Keywords: cellulase, EFBs, rice bran , Trichoderma sp. , wheat bran
Upaya Meningkatkan Kepedulian Masyarakat Dalam Pembayaran Pajak Bumi dan Bangunan Elda Ermawati; Hanida Hanida; Muhammad Nasir; Novita Ariani; Salaras Wita; Siti Nabila Safarina
MENGABDI : Jurnal Hasil Kegiatan Bersama Masyarakat Vol. 2 No. 5 (2024): Oktober: MENGABDI : Jurnal Hasil Kegiatan Bersama Masyarakat
Publisher : Asosiasi Riset Ekonomi dan Akuntansi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/mengabdi.v2i5.908

Abstract

Land and Building Tax (PBB) is one of the revenues for local governments which is very important for funding infrastructure development, health services, education and other public services. PBB has a very significant role in community compliance and awareness in paying PBB in various regions is still said to be low. This is usually caused by several factors such as a lack of socialization, minimal transparency in the use of PBB funds, and low public awareness of the use of PBB payments, which is the main cause of low taxpayer compliance. The aim of this research is to identify strategies to be implemented to increase public awareness and compliance in paying PBB. This research uses a qualitative approach using observation and documentation methods. This research shows that the results show that by having regular outreach campaigns or outreach, utilizing information technology in the payment process, as well as developing a compensation and public quality improvement system funded by PPB, it will be an effective step to increase public compliance in paying taxes. Apart from that, involving several community leaders and non-governmental organizations in tax awareness outreach or education is also able to strengthen community responsibility and participation in regional development. By implementing existing strategies, it is hoped that we will be able to overcome problems such as low awareness and low community compliance in PBB payments, which will then be able to support the sustainability of the ability to achieve goals in implementing regional development programs
Cervical Cancer with Radiotherapy Treatment Novita Ariani; Herli, Muhammad Azhari; Laila, Nurul
As-Shiha: Jurnal Kesehatan Vol. 4 No. 2 (2024): As-Shiha: Jurnal Kesehatan
Publisher : Fakultas MIPA dan Kesehatan, Universitas Muhammadiyah Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Cervical cancer is an abnormal growth of cells in the cervix, which its etiological agent is infected by the human papillomavirus. Globally, cervical cancer is the fourth most common cancer in women, one of the most frequently diagnosed cancer, and a cause of cancer-related death. The Global Cancer Statistics 2022, censused approximately 660,000 new cases and 350,000 deaths worldwide. Therefore, to contrast cervical cancer as a public health problem, the World Health Organization in 2020, conducted a global health strategy with tertiary interventions: (1) prevention through HPV vaccination; (2) screening and precancerous lesions treatment; and (3) adequate treatment of invasive cervical. Currently, there are three therapeutic modalities which are surgery, chemotherapy, and radiotherapy. These may include one or a combination of surgery, chemotherapy and radiotherapy. Radiotherapy is a major treatment in the management of cervical cancer, which uses high energy x-rays.
Efek Pemberian Larutan Ekstrak Akar Kayu Kuning terhadap Histopatologi Ginjal Mencit yang Diinduksi D-Galaktosa Zehan Afifa Yusran; Biomechy Oktomalio Putri; Miftah Irramah; Tofrizal; Liganda Endo Mahata; Novita Ariani
Jurnal Kesehatan Masyarakat Indonesia (JKMI) Vol. 2 No. 3 (2025): April
Publisher : Publikasi Inspirasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62017/jkmi.v2i3.4113

Abstract

D-galactose is a reducing sugar that induces oxidative stress by increasing the production of Reactive Oxygen Species (ROS) and Advanced Glycation End-products (AGEs), processes also associated with aging. Akar kayu kuning (Arcangelisia flava Merr.) extract contains antioxidant compounds that neutralize free radicals and mitigate oxidative stress. This study aimed to evaluate the effect of akar kayu kuning extract on the histopathological alterations of the kidneys in D-galactose-induced mice (Mus musculus). A true experimental study with a post-test-only control group design was conducted using 25 mice, divided into five groups: a negative control, a positive control (administered D-galactose at 150 mg/kgBW), and three experimental groups that received akar kayu kuning extract at doses of 250 mg/kgBW, 500 mg/kgBW, and 750 mg/kgBW following D-galactose induction. Kidney tissues were stained with hematoxylin and eosin (HE), and the extent of histopathological damage was quantified using ImageJ software. Statistical analysis using the Kruskal-Wallis test revealed significant differences between the experimental groups and the positive control (p < 0.05). The findings demonstrate that akar kayu kuning extract significantly reduces kidney histopathological damage in D-galactose-induced mice, highlighting its potential as a natural antioxidant for preventing oxidative stress-related renal impairment.
Gambaran CT Scan Kepala Pasien Trauma Kepala di RSUP Dr. M Djamil Padang Tahun 2021 Hafizah Putri Tasyah; Avit Suchitra; Rina Gustia; Novita Ariani; Dina Arfiani Rusjdi; Aswiyanti Asri
Jurnal Kesehatan Masyarakat Indonesia (JKMI) Vol. 2 No. 4 (2025): Juli
Publisher : Publikasi Inspirasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62017/jkmi.v2i4.4799

Abstract

Tujuan : mengetahui gambaran CT Scan kepala pasien trauma kepala di RSUP Dr. M. Djamil Padang pada tahun 2021. Metode : Penelitian ini adalah penelitian deskriptif retrospektif. Pengambilan data dilakukan di bagian Radiologi RSUP Dr. M Djamil Padang pada 8 Desember – 22 Desember 2022. Data diambil dalam periode bulan Januari – Desember 2021. Data dianalisis dengan menggunakan analisis univariat. Data dinyatakan dalam bentuk distribusi frekuensi. Hasil: Hasil penelitian ini adalah 357 sampel hasil CT Scan pasien yang memiliki diagnosis trauma kepala. sebanyak 72,5 % adalah laki-laki dan 27,5 % perempuan dari 357 sampel tersebut. Penderita trauma kepala paling banyak berusia 19-59 tahun (51,0 %). Gambaran lesi intrakranial yang terbanyak adalah lesi multipel ( 23,5 %). Kejadian fraktur maksilofasial ditemukan sebanyak 63 kejadian dari 357 pasien trauma kepala. Fraktur mandibular merupakan jenis fraktur yang banyak ditemukan yaitu 26 (7,2 %) kejadian. Fraktur calvaria ditemukan sebanyak 190 kejadian dari 357 pasien. Fraktur os frontal paling banyak ditemukan dengan 52 (14,6 5 %) kejadian Kesimpulan: penderita trauma kepala lebih banyak laki-laki dan lebih banyak pada usia 19-59 tahun. Gambaran lesi multipel paling banyak ditemukan pada gambaran Brain CT Scan. Kejadian fraktur mandibular yang paling banyak untuk fraktur maksilofasial. Fraktur frontal ditemukan paling banyak untuk fraktur calvaria.
Cycle Threshold Value and Absolute Lymphocyte Count Relationship with Severity of COVID-19 M. Alfian Agustian; Andani Eka Putra; Cimi Ilmiawati; Novita Ariani; Linosefa Linosefa
Vitalitas Medis : Jurnal Kesehatan dan Kedokteran Vol. 2 No. 3 (2025): Juli: Vitalitas Medis : Jurnal Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/vimed.v2i3.1964

Abstract

Coronavirus Disease 2019 (COVID-19) is a case that spread to many countries, including Indonesia, due to of SARS-CoV-2 transmission. West Sumatra, especially Padang city, is one of the highest spread of COVID-19 cases in Indonesia. This study aimed to examine the relation between Ct value and absolute lymphocyte count with the severity of COVID-19. The type of this research was analytic observational with the cross sectional study. We collected 106 patients data in Dr. M. Djamil Padang hospital from moderate to critical severity from June-August 2021. The data were collected and processed using convenient sampling which was then tested using Spearman correlation, One Way ANOVA, and Kruskal-Wallis tests. The results showed that most patients with confirmed COVID-19 were at the age of 56 to 65 years (30.2%), were women (51.9%), and had hypertension comorbidity (27.6%). We found that the median (IQR) of the Ct value is 23.5(10) and the mean ± SD of absolute lymphocyte count is 1213±56. There was a relation between Ct value and severity of COVID-19 (p=0.019), absolute lymphocyte count and severity of COVID-19 (p<0.01), and weak negative correlation of Ct value and absolute lymphocyte count (p=0.040, r=-0.200). Increasing viral load may elicit higher immune response clinically in moderate to critical COVID-19 patients.
Demographic, Clinical, and Treatment Factors That Affect the Five Years Survival of Thyroid Cancer Patients Alika Ristama Nigandiva; Daan Khambr; Saptino Miro; Novita Ariani; Rony Rustam; Dina Arfiani Rusjdi
Jurnal Kesehatan Masyarakat Indonesia (JKMI) Vol. 1 No. 3 (2024): April
Publisher : Publikasi Inspirasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62017/jkmi.v1i3.1018

Abstract

Thyroid cancer is the most common malignancy of the endocrine glands, the incidence of thyroid cancer in Indonesia ranks ninth after other types of cancer, it is known that the survival rate of thyroid cancer is better when compared to other types of cancer because thyroid cancer has a slow growth rate. Several demographic factors such as age and gender, clinical factors and treatments factors can affect the survival rate of thyroid cancer patients. This study was conducted to analyze the influence of demographic, clinical, and management factors on thyroid cancer survival rates at Dr. M. Djamil Padang Hospital. This study is an observational analytic study with a retrospective cross-sectional design. Sampling was done by total sampling technique. Data collection is done through patient medical record data. The results showed a five-year survival rate for thyroid cancer of 86.7%. Age, histopathological type, metastases, tumor extension, and management were significantly related to survival (p=0.013) (p=0.000), (p=0.001), (p=0.000) and (p=0.001).  Factors that have a significant relationship with survival rate are age, histopathological type, tumor extension, treatment, and metastases, and those that most influence survival rate are non-operative management and regional extension
Co-Authors Alika Ristama Nigandiva Andani Eka Putra Aswiyanti Asri Avit Suchitra Daan Khambr Dina Arfiani Rusjdi Eka Triwahyuni Elda Ermawati Hafizah Putri Tasyah Hanida Hanida Haznan Abimanyu Herli, Muhammad Azhari Ilmiawati, Ilmiawati Linosefa Linosefa M. Alfian Agustian Mahata, Liganda Endo Miftah Irramah Muhammad Nasir Nurul Laila, Nurul Putri, Biomechy Oktomalio Rina Gustia Rony Rustam Salaras Wita Saptino Miro Siti Nabila Safarina Tofrizal Trisanti Anindyawati Yosi ARISTIAWAN Zehan Afifa Yusran