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PEMBERDAYAAN MASYARAKAT DI NAGARI LUMPO KABUPATEN PESISIR SELATAN Yusrawati Yusrawati; Yulizawati Yulizawati; Lusiana El Sinta Bustami; Aldina Ayunda Insani; Vaulinne Basyir; Hudila Rifa Karmila; Feni Andriani; Erda Mutiara Halida; Fitrayeni Fitrayeni; Uliy Iffah; Miranie Safaringga; Laila Rahmi; Rafika Oktova; Ulfa Farah Lisa; Muhammad Iqbal; Rahmat Syawqi; Syandrez Prima Putra; Liganda Endo Mahata; Elfira Yusri
BULETIN ILMIAH NAGARI MEMBANGUN Vol 2 No 4 (2019)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Pesisir Selatan Regency is one of the districts with 15 sub-districts with the largest population in IV Jurai District. The number of deaths per year on the South Coast fluctuates. In 2015 the number of infant deaths increased from 6 to 42 people (male 29 and 13 female) from the previous year, AKABA of 47 from 18 in the previous year. There were 16 toddlers with herniated nutrition and many pregnant women, namely around 273 pregnant women. Based on a preliminary study conducted by the activity implementation team at the Lumpo Public Health Center, IV Jurai District, Pesisir Selatan Regency, it is known that there is no ultrasound examination facility in pregnancy and prenatal yoga facilities at the Lumpo Puskesmas, besides that there are no similar activities carried out at SD Negeri 016 and MTsN. Nagari Lumpo which is included in the work area of Lumpo Puskesmas. Several tests can be done during pregnancy as an effort to detect early and prevent complications and growth disorders in the fetus. Among others, by monitoring weight gain during pregnancy, conducting general examinations (vital signs), physical examinations that focus on the breasts, abdomen, genitalia with inspection, palpation, auscultation, and percussion, ultrasonography (USG) examinations, and performing supporting examinations in the form of laboratory examination (hemoglobin examination). The result of this activity is an increase in each target group's quality of life by the stages of life after this activity.

Peningkatan Komitmen Penanggulangan Covid-19 Mahasiswa melalui Webinar dan Deklarasi SIAGA SAKATO Liganda Endo Mahata; Fitrisia Amelin; Fathiyyatul Khaira; Denada Florencia Leona; Andani Eka Putra; Rizanda Machmud; Irvan Medison; Hardisman Hardisman; Yefri Zulfiqar; Fenty Anggraini; Linosefa Linosefa; Desy Nofita Sari; Rahmat Syawqi
Warta Pengabdian Andalas Vol 28 No 3 (2021)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.28.3.225-231.2021

The Covid-19 virus is transmitted from human to human through close contact with infected people through their respiratory droplets. A person can also be infected by touching an object contaminated with SARS-CoV-2 and then followed by reaching the eyes, nose, or mouth. Implementing the health protocol is necessary to reduce the number of virus transmissions. In addition, to increase the community's immune against Covid-19, WHO and the government have been developing a vaccination program. However, the recommendation from the latest research stated that people still have to obey the health protocol even after being vaccinated. The purpose of this community service was to help the government to increase people's understanding of the importance of implying health protocols, even after vaccination, to suppress Covid-19 cases. The method used is by holding an online event called a Webinar. It followed by a statement with audiences to commit to implementing the health protocol led by the Rector of Andalas University, then called a SIAGA SAKATO declaration. The activity began with a pre-test questionnaire for initial information collection, followed by education about Covid-19 prevention from the experts to the 512 students. The activity ended with the final data collection using a posttest questionnaire to test the student knowledge after the education. Paired t-test analysis showed a significant increase in student commitment after attending the Webinar (P≤0.05). Based on these results, the Webinar increases students' understanding of the importance of the health protocol in reducing the Covid-19 cases.

Peningkatan Pengetahuan Masyarakat tentang Bahaya Paparan Mikroplastik dan Dampaknya bagi Kesehatan Ilmiawati Ilmiawati; Liganda Endo Mahata; Gestina Aliska; Erlina Rustam; Yusticia Katar; Rahmatini Rahmatini; Julizar Julizar; Elly Usman
Warta Pengabdian Andalas Vol 29 No 3 (2022)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.29.3.305-311.2022

Plastic is a global problem; plastic pollution production reaches 350 million tons annually. This plastic pollution will be degraded into microplastic. This microplastic will pollute the environment and negatively impacted health if exposed too much. Recent research has found microplastics in clothes, toys, and even food. The Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Andalas conducts outreach to the public to enhance the general public's understanding of microplastics and their impact on health. The outreach activity began with filling out a pre-test to assess the public's understanding of microplastics. Followed by education about microplastic exposure, the dangers of microplastics, and education about a healthy lifestyle to reduce sources of microplastic exposure. The event ended with filling out a post-test by participants. Paired t-test analysis on pre-test and post-test data showed an increase in public understanding regarding microplastics, sources of exposure, health impacts and ways to reduce microplastic exposure. Based on these results, it can be concluded that the provision of public service can increase public understanding regarding the sources of microplastics and their impact on health and encourage people to live a healthy lifestyle that minimizes exposure to microplastics.

Profil Pasien COVID-19 dengan Komorbid yang Dirawat di RSUP Dr. M. Djamil Padang Hamni Tanjung; Julizar Julizar; Sabrina Ermayanti; Deddy Herman; Liganda Endo Mahata; Syandrez Prima Putra
Jurnal Ilmu Kesehatan Indonesia Vol 4 No 1 (2023): Maret 2023
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v4i1.971

Latar Belakang: Coronavirus Disease 2019 (COVID-19) yang disebabkan Severe Acute Respiratory Coronavirus-2 (SARS-CoV-2) telah menjadi perhatian dunia sejak awal ditemukan hingga saat ini. Keparahan kondisi pasien COVID-19 dengan komorbid dipengaruhi dengan berbagai faktor yang dapat meningkatkan morbiditas dan mortalitas pasien COVID-19. Objektif: Penelitian ini bertujuan untuk mengetahui profil pasien COVID-19 dengan komorbid yang dirawat di RSUP Dr. M. Djamil Padang. Metode: Jenis penelitian ini merupakan observasional deskriptif dengan pendekatan cross-sectional. Data penelitian diambil dari data rekam medis dengan teknik pengambilan total sampling pada pasien yang dirawat pada 1 Oktober sampai 31 Desember 2020. Hasil: Penelitian ini mendapatkan dari total 144 pasien, 34% pasien COVID-19 dengan komorbid merupakan kelompok usia 50-59 tahun, 50,7% berjenis kelamin laki-laki, 59,7% memiliki riwayat pendidikan tingkat menengah dan 53,5% berstatus IMT obesitas. Komorbid terbanyak yang ditemukan adalah 29,2% hipertensi dengan 73,6% pasien memiliki lebih dari satu komorbid, sebanyak 77,1% merupakan COVID-19 derajat sedang dengan 71,5% memiliki lama rawatan 14 hari atau kurang, serta 62,5% memiliki luaran COVID-19 sembuh. Kesimpulan: Penelitian ini menemukan sebagian besar pasien COVID-19 dengan komorbid yang dirawat merupakan kelompok usia tua, dengan komorbid terbanyak hipertensi, sebagian besar memiliki lebih dari satu komorbid, mengalami derajat sakit sedang dengan lama rawatan 14 hari atau kurang, dan luaran sembuh.

Edukasi Masyarakat Mengenai Toksikan Abadi (Forever Chemicals) dalam Kosmetik Bersifat Waterproof Ilmiawati Ilmiawati; Liganda Endo Mahata; Gestina Aliska; Rahmatini Rahmatini; Julizar Julizar; Yusticia Katar; Erlina Rustam; Elly Usman
Warta Pengabdian Andalas Vol 30 No 4 (2023)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.30.4.708-714.2023

Per- and poly-fluoroalkyl substances (PFAS) are synthetic chemicals added to cosmetics for their waterproof property to obtain a long-lasting application. PFAS is highly persistent, hence called the forever chemicals. This community outreach was aimed to educate the public on PFAS exposure through waterproof cosmetics and its health implications. Our webinar was attended by 84 people, 50 of whom responded to the pre-and post-test. An expert delivered the presentation of the educational content. There was an increase in attendees’ test scores from 56.4±21.3 to 88.4±19.0 (mean±SD; paired t-test, p<0.05). The webinar improved attendees’ knowledge of PFAS exposure from waterproof cosmetics and its potential effects on health.

Efek Pemberian Larutan Ekstrak Akar Kayu Kuning terhadap Histopatologi Ginjal Mencit yang Diinduksi D-Galaktosa Zehan Afifa Yusran; Biomechy Oktomalio Putri; Miftah Irramah; Tofrizal; Liganda Endo Mahata; Novita Ariani
Jurnal Kesehatan Masyarakat Indonesia (JKMI) Vol. 2 No. 3 (2025): April
Publisher : Publikasi Inspirasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62017/jkmi.v2i3.4113

D-galactose is a reducing sugar that induces oxidative stress by increasing the production of Reactive Oxygen Species (ROS) and Advanced Glycation End-products (AGEs), processes also associated with aging. Akar kayu kuning (Arcangelisia flava Merr.) extract contains antioxidant compounds that neutralize free radicals and mitigate oxidative stress. This study aimed to evaluate the effect of akar kayu kuning extract on the histopathological alterations of the kidneys in D-galactose-induced mice (Mus musculus). A true experimental study with a post-test-only control group design was conducted using 25 mice, divided into five groups: a negative control, a positive control (administered D-galactose at 150 mg/kgBW), and three experimental groups that received akar kayu kuning extract at doses of 250 mg/kgBW, 500 mg/kgBW, and 750 mg/kgBW following D-galactose induction. Kidney tissues were stained with hematoxylin and eosin (HE), and the extent of histopathological damage was quantified using ImageJ software. Statistical analysis using the Kruskal-Wallis test revealed significant differences between the experimental groups and the positive control (p < 0.05). The findings demonstrate that akar kayu kuning extract significantly reduces kidney histopathological damage in D-galactose-induced mice, highlighting its potential as a natural antioxidant for preventing oxidative stress-related renal impairment.

PEMBERDAYAAN MASYARAKAT DI NAGARI LUMPO KABUPATEN PESISIR SELATAN Yusrawati Yusrawati; Yulizawati Yulizawati; Lusiana El Sinta Bustami; Aldina Ayunda Insani; Vaulinne Basyir; Hudila Rifa Karmila; Feni Andriani; Erda Mutiara Halida; Fitrayeni Fitrayeni; Uliy Iffah; Miranie Safaringga; Laila Rahmi; Rafika Oktova; Ulfa Farah Lisa; Muhammad Iqbal; Rahmat Syawqi; Syandrez Prima Putra; Liganda Endo Mahata; Elfira Yusri
BULETIN ILMIAH NAGARI MEMBANGUN Vol. 2 No. 4 (2019)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v2i4.130

Pesisir Selatan Regency is one of the districts with 15 sub-districts with the largest population in IV Jurai District. The number of deaths per year on the South Coast fluctuates. In 2015 the number of infant deaths increased from 6 to 42 people (male 29 and 13 female) from the previous year, AKABA of 47 from 18 in the previous year. There were 16 toddlers with herniated nutrition and many pregnant women, namely around 273 pregnant women. Based on a preliminary study conducted by the activity implementation team at the Lumpo Public Health Center, IV Jurai District, Pesisir Selatan Regency, it is known that there is no ultrasound examination facility in pregnancy and prenatal yoga facilities at the Lumpo Puskesmas, besides that there are no similar activities carried out at SD Negeri 016 and MTsN. Nagari Lumpo which is included in the work area of Lumpo Puskesmas. Several tests can be done during pregnancy as an effort to detect early and prevent complications and growth disorders in the fetus. Among others, by monitoring weight gain during pregnancy, conducting general examinations (vital signs), physical examinations that focus on the breasts, abdomen, genitalia with inspection, palpation, auscultation, and percussion, ultrasonography (USG) examinations, and performing supporting examinations in the form of laboratory examination (hemoglobin examination). The result of this activity is an increase in each target group's quality of life by the stages of life after this activity.

EFEK EKSTRAK DAUN KEMANGI (Ocimum basilicum L.) TERHADAP KADAR HIGH-DENSITY LIPOPROTEIN TIKUS (Rattus norvegicus) MODEL ATEROSKLEROSIS Mazara, Fitria; Mahata, Liganda Endo; Kadri, Husnil; Putri, Biomechy Oktomalio; Ali, Hirowati; Khaira, Fathiyyatul; Rusjdi, Dina Arfiani
Mandala Of Health Vol 17 No 2 (2024): Mandala of Health: a Scientific Journal
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mandala.2024.17.2.11432

Atherosclerosis is the cardiovascular disease’s main pathological mechanism. Basil leaves are food companion that s widely consumed by Indonesians and contains phenolic and flavonoid bioactive compounds that can increase HDL levels. The purpose of this study was to see the effect of basil leaves extract (Ocimum basilicum L.) on HDL levels in atherosclerosis model rat. This study was conducted using the post test only control group design method on 29 rats. The rats were divided into 5 groups, K-, K+, P1, P2, and P3. K- is group of rats without treatment. K+ was treated with partial carotid ligation (PCL) and high fat diet (HFD), P1 was treated with PCL, HFD and given a dose of 100 mg/kgB basil leaves extract, P2 was treated with PCL, HFD and given a dose of 200 mg/kgBB basil leaves extract, P3 was treated with PCL, HFD and given simvastatin 1.5 mg/rat/day. HFD was given for 7 days, basil leaves extract and simvastatin given for 14 days using oral feeding tube. HDL levels tested with CHOD-PAP method using a microlab 300 spectrophotometer. The result from this study were analyzed by Saphiro-Wilk test, and Kruskal-Wallis test. The mean HDL levels obtained in the K- group were 52,65(49,70‒68.10) mg/dL, K+ 49,67±8,77 mg/dL, P1 52.70±1.58 mg/dL, P2 54.40±9.94 mg/dL, P3 58,05 ±5,34 mg/dL. The results showed there was a non-significant increase in HDL levels (p=0.377) in atherosclerosis model rat by giving basil leaves extract on both dose, and simvastatin.

The Effect of Basil Leaves Extract (Ocimum basilicum) on The Triglyceride Level in Atherosclerosis Rats Atmi, Serly Rahma; Mahata, Liganda Endo; Rahmatini, Rahmatini; Rofinda, Zelly Dia; Ali, Hirowati; Aliska, Gestina; Khaira, Fathiyyatul
Majalah Obat Tradisional Vol 30, No 2 (2025)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.94222

Atherosclerosis is the main cause of cardiovascular disease (CVD) characterized by fat accumulation and transformation, inflammation, smooth muscle cell proliferation, and necrotic cell remnants in the tunica intima of blood vessels. Basil leaves are known to contain active biochemical compounds that have the potential to reduce lipids. This is an experimental study that investigated the effect of basil leaves on rat triglyceride levels in atherosclerotic models. This research consisted of five groups of rats that were induced atherosclerosis by partial carotid ligation and a high-fat diet for 7 days. The treatment group was given basil leaves extract ethanol with 100 mg/kgBW, 200 mg/kgBW dose, and simvastatin 1,5mg/rat/day. Examination of triglyceride levels by enzymatic calorimetry GPO-PAP method using Micro Lab 300. The data were analyzed using One-way ANOVA and Post Hoc Bonferroni. The results showed that there was an average decrease in triglyceride levels in rats given basil leaves extract with 100 mg/kg BW dose and indicated that the Ocimum basilicum leaves extract affected triglyceride levels in rats induced by atherosclerosis.

SYNERGISTIC COMBINATION OF JAVA PLUM (SYZYGIUMCUMINI(L.) SKEELS) LEAF EXTRACT AND VITAMIN C ON ASPARTATE AMINOTRANSFERASE AND ALANINE AMINOTRANSFERASE LEVELS IN LEAD ACETATE-INDUCED RAT Ikhsan, M; Rita, Rauza Sukma; Elmatris, Elmatris; Alioes, Yustini; Mahata, Liganda Endo; Almurdi, Almurdi
EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan Vol. 2 No. 3 (2025): EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan, September 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/empiris.v2i3.1708

Lead (Pb) is a toxic metal that is used to trigger oxidative stress. Oxidative stress causes damage to organs, especially the liver increasing aspartate aminotransferase (AST) and alanine aminotransferase (ALT). This study aims to determine the synergistic effect of antioxidant as Java plum leaf extract and vitamin C together on lead-induced levels of AST and ALT in rats.This type of research is true experimental research with a randomized posttest-only-control group design. The study used 20 male white rats which were divided into 4 groups. The treatment was carried out for 30 days. The examination for AST and ALT levels using the Micro Lab 300 with the Sample Star method. Data analysis was performed by using One-way Anova and Post Hoc-Turkey HSD.In this study, The results were obtained in the form of a decrease in AST and ALT levels in rats that had been induced lead acetate 40 mg/KgBW by administration of Java plum leaf extract dose 75 mg/KgBW and vitamin C dose 35 mg/KgBW as well as the administration of Java plum leaf extract at a dose of 150 mg / KgBB and vitamin C dose of 75 mg / KgBB with significant influence at the lower dose (p=0,01).It can be concluded that administrating of Java plum leaf extract dose 75 mg/KgBB and vitamin C dose 35 mg/KgBB was effective to protect the liver based on the decrease of AST and ALT levels in rats that had been induced lead acetate dose 40 mg/KgBB

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