Article Per Year (5 Year)
p-Index From 2020 - 2025
1.259
P-Index
This Author published in this journals
All Journal Biomedical Journal of Indonesia Jurnal Ilmiah Universitas Batanghari Jambi Bioscientia Medicina : Journal of Biomedicine and Translational Research Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Kesehatan Masyarakat Indonesia (JKMI)
Avit Suchitra
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

Published : 6 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 6 Documents
Search

 1 
Comparison of Incident of Chronic Pain Post Operations of Preperitoneal Transabdominal Herniorafi Laparoscopy (TAPP) and Totally Extraperitoneal (TEP) in General Hospital Dr. M. Djamil Padang Ramata, Yudi Ichsan; M. Iqbal Rivai; Avit Suchitra
Biomedical Journal of Indonesia Vol. 7 No. 1 (2021): Biomedical Journal of Indonesia
Publisher : Fakultas Kedokteran Universitas Sriwijaya (Faculty of Medicine, Universitas Sriwijaya) Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v7i1.278

Abstract

A B S T R A C TIntroduction : Inguinal herniation is a protrusion of peritoneal component throughabdominal wall caused by the weakness of aponeurotica tissue of abdomen. Inguinalherniation is the most common herniation cases in which 291.145 patient registeredin Indonesia at 2012 and 87 patients in General Government Hospital of M. DjamilPadang at 2017-2018. Herniation treatment is consisted of herniorrhapylaparoscopy using the TEP or TAPP techniques and both of them are related to theincidence of chronical post-operative pain that was defined by IASP as anuncomfortable sensation lasting for more than 3 months. Method: This researchwas using retrospective study design. The research was conducted at RSUP Dr. M.Djamil Padang in August – October 2020 with 54 samples. Result: The study foundthere was 54 cases of inguinal herniation fit to the inclusion criteria with peak ageof 82 years old and average of 59.1 years old. Most patients were male (79.62 %).There were 2 patients having chronic pain (7.41%) after herniorrhapy using the TAPPtechnique and 1 more (3.71%) having chronic pain with TEP technique. Bivariateanalysis was done by Fisher Exact Test and the study concluded there was nostatistical significance in relationship of chronic post-operative pain incidence withthe particular technique chosen at herniorrhapy laparoscopy (p=1.000). Conclusion:There was no significant relationship between the incidence of postoperative chronicpain in patients undergoing laparascopic hernioraphy and TEP or TAPP procedure.
Pengaruh Mobilisasi Dini Terhadap Penurunan Skala Nyeri Pada Pasien Post Operasi Laparatomi di Ruangan Intensive Care Unit Darmawidyawati Darmawidyawati; Avit Suchitra; Emil Huriani; Susmiati Susmiati; Dally Rahman; Elvi Oktarina
Jurnal Ilmiah Universitas Batanghari Jambi Vol 22, No 2 (2022): Juli
Publisher : Universitas Batanghari Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33087/jiubj.v22i2.2300

Abstract

Post Laparatomy pain can be minimized by giving pharmacological and non-pharmacological therapy. Nurses has a role to reduce the pain scale of patients with independent nursing care. One of them is early mobilization therapy. This study aims to determine the effect of early mobilization of decrease in pain scale in patients post operations laparatomy. True-experimental research design and use the pretest-posttest with a control group approach. The sampling technique uses Consecutive Sampling The number of samples was 30 people using the Slovin formula. Collection of pain scale data uses C.P.O.T and pain scale collected pre and post mobilization action, then analyzed univariate and bivariate with a Mann-Whiteney U . The results of the study were obtained by p-value <0.005 there was an effect of early mobilization of the reduction in pain scale. This research suggested that early mobilization actions can be used as one of the independent nursing interventions in dealing with pain problems in post laratomy patients at Intensive Care Unit
The Significance of TGF-β Expression in Predicting Lymphovascular Invasion and Lymph Node Metastasis in Colorectal Cancer Aini, Julpa Nurul; Aswiyanti Asri; Noza Hilbertina; Tofrizal; Avit Suchitra; Husna Yetti
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 1 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i1.1182

Abstract

Background: Colorectal cancer (CRC) is a major health burden globally. The prognosis of CRC is strongly influenced by the presence of lymphovascular invasion (LVI) and lymph node (LN) metastasis. Transforming growth factor-beta (TGF-β) is a cytokine with a complex role in CRC progression. This study aimed to evaluate the significance of TGF-β expression in predicting LVI and LN metastasis in CRC. Methods: This cross-sectional study involved 50 patients diagnosed with CRC. The expression of TGF-β was assessed using immunohistochemical staining and the Allred scoring system. The relationship between TGF-β expression and the presence of LVI and LN metastasis was analyzed using the Chi-square test. Results: High TGF-β expression was significantly associated with both LVI (p = 0.011) and LN metastasis (p = 0.012) in CRC. Patients with high TGF-β expression had a higher risk of LVI and LN metastasis compared to those with low TGF-β expression. Conclusion: TGF-β expression is a significant predictor of LVI and LN metastasis in CRC. This finding has potential implications for risk stratification and treatment decisions in CRC patients.
Gambaran CT Scan Kepala Pasien Trauma Kepala di RSUP Dr. M Djamil Padang Tahun 2021 Hafizah Putri Tasyah; Avit Suchitra; Rina Gustia; Novita Ariani; Dina Arfiani Rusjdi; Aswiyanti Asri
Jurnal Kesehatan Masyarakat Indonesia (JKMI) Vol. 2 No. 4 (2025): Juli
Publisher : Publikasi Inspirasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62017/jkmi.v2i4.4799

Abstract

Tujuan : mengetahui gambaran CT Scan kepala pasien trauma kepala di RSUP Dr. M. Djamil Padang pada tahun 2021. Metode : Penelitian ini adalah penelitian deskriptif retrospektif. Pengambilan data dilakukan di bagian Radiologi RSUP Dr. M Djamil Padang pada 8 Desember – 22 Desember 2022. Data diambil dalam periode bulan Januari – Desember 2021. Data dianalisis dengan menggunakan analisis univariat. Data dinyatakan dalam bentuk distribusi frekuensi. Hasil: Hasil penelitian ini adalah 357 sampel hasil CT Scan pasien yang memiliki diagnosis trauma kepala. sebanyak 72,5 % adalah laki-laki dan 27,5 % perempuan dari 357 sampel tersebut. Penderita trauma kepala paling banyak berusia 19-59 tahun (51,0 %). Gambaran lesi intrakranial yang terbanyak adalah lesi multipel ( 23,5 %). Kejadian fraktur maksilofasial ditemukan sebanyak 63 kejadian dari 357 pasien trauma kepala. Fraktur mandibular merupakan jenis fraktur yang banyak ditemukan yaitu 26 (7,2 %) kejadian. Fraktur calvaria ditemukan sebanyak 190 kejadian dari 357 pasien. Fraktur os frontal paling banyak ditemukan dengan 52 (14,6 5 %) kejadian Kesimpulan: penderita trauma kepala lebih banyak laki-laki dan lebih banyak pada usia 19-59 tahun. Gambaran lesi multipel paling banyak ditemukan pada gambaran Brain CT Scan. Kejadian fraktur mandibular yang paling banyak untuk fraktur maksilofasial. Fraktur frontal ditemukan paling banyak untuk fraktur calvaria.
Differential Roles of CD117 and Ki67 in Gastrointestinal Stromal Tumors: Diagnostic Utility Versus Prognostic Power Fitri Nur Handriyani; Noza Hilbertina; Henny Mulyani; Loli Devianti; Avit Suchitra; Husna Yetti
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 7 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i7.1337

Abstract

Background: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the digestive tract, primarily driven by mutations in KIT or PDGFRA genes. CD117 (c-KIT) expression is a key diagnostic marker, while the Ki67 labeling index reflects cellular proliferation. Risk stratification, often using modified NIH criteria based on tumor size, mitotic rate, and location, guides prognosis and treatment. This study investigated the distinct roles of CD117 and Ki67 expression in relation to risk stratification in GIST patients. Methods: This cross-sectional analytical study examined 27 GIST cases diagnosed between January 2021 and December 2024 from three Indonesian hospitals. Formalin-fixed paraffin-embedded tissues were analyzed using immunohistochemistry for CD117 (clone YR145) and Ki67 (clone K2). CD117 positivity was defined as ≥5% tumor cell staining, and high Ki67 expression as >10% nuclear staining. Risk stratification utilized the modified NIH criteria. The Chi-square test assessed correlations (p<0.05 significance). Results: The cohort predominantly comprised patients >50 years (66.7%), males (59.3%), with gastric tumors (51.9%), large tumor size (>5cm in 96.3%), spindle cell morphology (77.8%), and high mitotic rates (74.1%). Most cases (85.2%) were classified as high-risk. CD117 was positive in 81.5% (22/27) of cases but showed no significant correlation with risk stratification (p=0.561). High Ki67 expression was found in 74.1% (20/27) of cases and demonstrated a significant positive correlation with high-risk stratification (p=0.002). The combination of CD117 and Ki67 status also showed a significant association with risk stratification (p=0.001). Conclusion: While CD117 expression remains a cornerstone for GIST diagnosis and targeted therapy selection, it did not correlate significantly with risk stratification in this cohort. Conversely, a high Ki67 labeling index was significantly associated with high-risk GIST, underscoring its potential as a valuable prognostic marker alongside established risk stratification parameters.
Differential Roles of CD117 and Ki67 in Gastrointestinal Stromal Tumors: Diagnostic Utility Versus Prognostic Power Fitri Nur Handriyani; Noza Hilbertina; Henny Mulyani; Loli Devianti; Avit Suchitra; Husna Yetti
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 7 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i7.1337

Abstract

Background: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the digestive tract, primarily driven by mutations in KIT or PDGFRA genes. CD117 (c-KIT) expression is a key diagnostic marker, while the Ki67 labeling index reflects cellular proliferation. Risk stratification, often using modified NIH criteria based on tumor size, mitotic rate, and location, guides prognosis and treatment. This study investigated the distinct roles of CD117 and Ki67 expression in relation to risk stratification in GIST patients. Methods: This cross-sectional analytical study examined 27 GIST cases diagnosed between January 2021 and December 2024 from three Indonesian hospitals. Formalin-fixed paraffin-embedded tissues were analyzed using immunohistochemistry for CD117 (clone YR145) and Ki67 (clone K2). CD117 positivity was defined as ≥5% tumor cell staining, and high Ki67 expression as >10% nuclear staining. Risk stratification utilized the modified NIH criteria. The Chi-square test assessed correlations (p<0.05 significance). Results: The cohort predominantly comprised patients >50 years (66.7%), males (59.3%), with gastric tumors (51.9%), large tumor size (>5cm in 96.3%), spindle cell morphology (77.8%), and high mitotic rates (74.1%). Most cases (85.2%) were classified as high-risk. CD117 was positive in 81.5% (22/27) of cases but showed no significant correlation with risk stratification (p=0.561). High Ki67 expression was found in 74.1% (20/27) of cases and demonstrated a significant positive correlation with high-risk stratification (p=0.002). The combination of CD117 and Ki67 status also showed a significant association with risk stratification (p=0.001). Conclusion: While CD117 expression remains a cornerstone for GIST diagnosis and targeted therapy selection, it did not correlate significantly with risk stratification in this cohort. Conversely, a high Ki67 labeling index was significantly associated with high-risk GIST, underscoring its potential as a valuable prognostic marker alongside established risk stratification parameters.
Co-Authors Aini, Julpa Nurul Aswiyanti Asri Dally Rahman Darmawidyawati Darmawidyawati Dina Arfiani Rusjdi Emil Huriani Fitri Nur Handriyani Hafizah Putri Tasyah Henny Mulyani Husna Yetti Husna Yetti Loli Devianti M. Iqbal Rivai Novita Ariani Noza Hilbertina Oktarina, Elvi Prima Adelia Rachmita Ramata, Yudi Ichsan Rina Gustia Salmiah Agus Susmiati Susmiati Tofrizal Yenita .