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All Journal Padjadjaran Journal of Dentistry Padjadjaran Journal of Dental Researchers and Students
Achmad Syawqie
Universitas Padjadjaran
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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The effects of ethyl acetate fraction of Ananas Comosus (L.) Merr. of tongue cancer cell growth inhibition Supri’s Clone-1, invitro Martina, Maureen; Oewen, Roosje Rosita; Riyanti, Eriska; Syawqie, Achmad; Supriatno, S.
Padjadjaran Journal of Dentistry Vol 23, No 2 (2011): July
Publisher : Faculty of Dentistry Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (237.853 KB) | DOI: 10.24198/pjd.vol23no2.14017

Abstract

Ananas comosus (L.) Merr has several purposes which include antioxidant and anti-inflammatory activity that shows some pharmacological effects and the subject of anti-cancer or anti-cancer supporting material. The research objective was to analyze the effects of ethyl acetate fraction of Ananas comosus (L.) Merr. of tongue cancer cell growth inhibition Supri’s clone-1 (SP-C1). This type of study was a research laboratory. Next, cell growth inhibition testing by the ethyl acetate fraction of Ananas comosus (L.) Merr. with various concentrations (0; 62.5; 125; 250; 250; 500 and 1000 microgram/ml) using the MTT assay test. Growth barriers identified by Biorad microplate tool reader with a wavelength of 540 nm. The number of SP-C1 cells examined was 2 x 104 cells/wells with incubation time 24 and 48 hours. Data were analyzed using a two-ways ANOVA followed by post hoc test (LSD test) with 95% significance level. The results showed ethyl acetate fraction of Ananas comosus (L.) Merr. able to inhibit the growth of cancer cells SP-C1. Various concentrations of ethyl acetate fraction of pineapple were highly significant, meaning that the concentration effect on cell growth of SP-C1. Similarly, incubation time effect on the growth of SP-C1 cells that were very meaningful. The biggest obstacle effect of ethyl acetate fraction of Ananas comosus (L.) Merr. occurred at a concentration of 1000 ug/ml (43.45%) with an incubation time of 48 hours. Conclusion of this study was the fraction of ethyl acetate Ananas comosus (L.) Merr. has the effect of inhibiting the growth of cancer cells SP-C1.
Peran Teknologi Haptik Virtual Reality dalam Pendidikan Kedokteran Gigi: Tinjauan Sistematik Abraari, Mohammad Agiel; Syawqie, Achmad; Nur'aeny, Nanan
Padjadjaran Journal of Dental Researchers and Students Vol 9, No 3 (2025): Oktober 2025
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjdrs.v9i3.65494

Abstract

Pendahuluan: Mahasiswa kedokteran gigi membutuhkan keterampilan motorik klinis yang baik, namun pelatihan konvensional seperti manekin memiliki keterbatasan dalam memberikan umpan balik sensorik. Teknologi haptic virtual reality (VR) menawarkan solusi modern dengan simulasi taktil yang realistis, namun efektivitasnya masih perlu dikaji secara sistematis. Studi ini bertujuan mengevaluasi efektivitas haptic VR dalam meningkatkan keterampilan motorik, pengetahuan, dan kepercayaan diri mahasiswa. Metode: Penelitian dilakukan melalui systematic review dengan pedoman PRISMA, mencakup 12 artikel dari database PubMed, Scopus, ScienceDirect, dan Google Scholar. Analisis dilakukan secara naratif karena heterogenitas studi. Hasil: menunjukkan bahwa haptic VR efektif dalam pelatihan prosedur seperti preparasi karies, scaling, veneer, dan pulpotomi. Mahasiswa mengalami peningkatan koordinasi tangan-mata, pemahaman prosedur, dan kepercayaan diri. Efektivitas dipengaruhi oleh kualitas perangkat, pengalaman pengguna, dan integrasi dalam kurikulum. Simpulan: haptic VR belum menggantikan metode tradisional, namun berpotensi sebagai alat bantu yang efektif, khususnya dalam pelatihan endodontik, periodontik, konservasi, prostodontik, dan kedokteran gigi anak.
Co-Authors Abraari, Mohammad Agiel Eriska Riyanti Maureen Martina, Maureen Nur'aeny, Nanan Roosje Rosita Oewen, Roosje Rosita Supriatno