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All Journal UNEJ e-Proceeding JURNAL CITRA KEPERAWATAN Nurse and Health: Jurnal Keperawatan JI-KES (Jurnal Ilmu Kesehatan) Jurnal Kreativitas PKM Abdimas Umtas : Jurnal Pengabdian kepada Masyarakat Jurnal Ilmu Keperawatan Jiwa Jurnal Aisyah : Jurnal Ilmu Kesehatan Jurnal Peduli Masyarakat Jurnal Pengabdian Masyarakat dalam Kesehatan PROFESSIONAL HEALTH JOURNAL Nursing and Health Sciences Journal (NHSJ) An Idea Health Journal Proceedings of the International Conference on Nursing and Health Sciences Jurnal Vokasi Kesehatan The Journal of Nursing and Midwifery Sciences Jurnal Keperawatan Prosiding Seminar Nasional Pengabdian Kepada Masyarakat: Peduli Masyarakat JI-KES (Jurnal Ilmu Kesehatan)
Mukhammad Toha
Program Studi DIII Keperawatan, Kampus Kota Pasuruan, Fakultas Keperawatan, Universitas Jember
Religion Agriculture, Biological Sciences & Forestry Arts Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Enhancing Wound Repair With Carica Papaya -Based Formulation: A Pretest-Posttest Control Group Trial Mokh. Sujarwadi; Mukhammad Toha; Ida Zuhroidah; Rondhianto Rondhianto; Dimas Hadi Prayoga; Fatimah Zahra; Nadia Rohmatul Laili
An Idea Health Journal Vol 6 No 01 (2026)
Publisher : PT.Mantaya Idea Batara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53690/ihj.v6i01.652

Abstract

Background: Natural products are increasingly favored in wound care due to concerns about antibiotic resistance and side effects of synthetic drugs. Carica papaya L., a tropical plant native to Central America and widely grown in Indonesia, contains bioactive compounds with properties essential for tissue repair. This study tests whether a topical Carica papaya formulation speeds up wound healing by measuring granulation and epithelialization. Methods: Using a quasi-experimental design. A total of 50 participants were divided into a control (standard wound care) and a treatment group (standard care + C. papaya extract). Analysis used the Paired T test. Result: Paired t-tests indicated no significant changes in the control group (p = 1.00). In contrast, the treatment group demonstrated statistically significant improvements in granulation (pre: 0.44 ± 0.51; post: 1.56 ± 0.51; t = -9.35, p < 0.001) and epithelialization (pre: 0.68 ± 0.47; post: 1.72 ± 0.46; t = -10.25, p < 0.001). Independent-samples t-tests confirmed significant differences between groups after the intervention (granulation: t = -9.35, p < 0.001; epithelialization: t = -10.25, p < 0.001). These results support the incorporation of C. papaya extract into evidence-based complementary wound management protocols. Conclusion: Carica papaya extract significantly enhances wound healing, promoting granulation and epithelialization. Thus, it may serve as an effective adjunctive therapy in clinical wound management.
Co-Authors Alex Prayoga, Dedy Apriana Rahmawati Bagus Dwi Cahyono Diana Nurmala Yulianasari Dimas Hadi Prayoga Eko Prasetya Widianto Fatimah Zahra Fatimah Zahra Fitriyah, Agustini Indriana Noor Istiqomah Laili, Nadia Rohmatul Mokh Sujawadi Mokh. Sujarwadi Nurfika Asmaningrum Nurfika Asmaningrum Nurfika Asmaningrum Nurul Huda Nurul Huda Nurul Huda Rondhianto Rondhianto Srengenge, Gawan Sujarwadi, Mokhammad Zahra , Fatimah Zuhroidah, Ida