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UJI AKTIVITAS ANTIOKSIDAN DAN TABIR SURYA EKSTRAK METANOL KULIT BUAH MARKISA UNGU (Passiflora edulis f. edulis Sims) DENGAN SPEKTROFOTOMETRI UV-VIS Sundu, Reksi; Jubaidah, Siti; Milasari, Novi; Adhila, Ghina
JFM (Jurnal Farmasi Malahayati) Vol 8, No 2 (2025)
Publisher : Jurnal Farmasi Malahayati (JFM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jfm.v8i2.21642

Abstract

Tabir surya dapat membantu mencegah efek buruk radiasi ultraviolet. Efektivitas tabir surya didasarkan pada penentuan nilai Sun Protection Factor (SPF) yang menunjukkan kemampuan produk tabir surya dalam melindungi kulit dari paparan sinar UV. Nilai SPF besar atau kecil dipengaruhi oleh kandungan antioksidan dan bahan aktif yang digunkan dalam membuat sediaan tabir surya. Antioksidan alamiah tubuh berfungsi sebagai sistem pertahanan untuk melindungi sel-selnya dari kerusakan yang disebabkan oleh radikal bebas. Ekstrak kulit buah markisa ungu mengandung senyawa karotenoid, polifenol, dan vitamin. Tujuan dari penelitian ini untuk mengetahui aktivitas antioksidan dan tabir surya ekstrak methanol kulit buah markisa ungu (Passiflora edulis f. edulis Sims). Metode penelitian menggunakan metode DPPH secara Spektrofotometri UV-Vis. Metode Penelitianmenggunakan metode DPPHsecara Spektrofotometri UV-Visc Hasil penelitian menunjukkan metabolit sekunder yang terdapat dalam ekstrak metanol kulit markisa ungu flavonoid, tanin, saponin, alkaloid, dan terpenoid. Aktivitas antioksidan ekstrak metanol kulit markisa ungu didapatkan nilai IC50 sebesar 125,13 ±13,22 termasuk dalam kategori sedang dan pembanding vitamin C sebesar 7,17 ± 0,60 termasuk dalam ketegori sangat kuat. Nilai tertinggi SPF terdapat pada konsentrasi 2.000 ppm yaitu 30,03 ± 0,24 dan termasuk dalam kategori tinggi
Pelatihan Pembuatan Cheese Cake Labu Kuning (Cucurbita moschata Duch.) sebagai Alternatif Makanan Fungsional dalam Pencegahan Stunting di Poyandu Kemuning, Sambutan Adhila, Ghina; Milasari, Novi; Sundu, Reksi; Namira, Nadine Anastasya Putri; Rachman, Nadya Rahmawati; Rachmanissa, Nadya; Nabila, Annisa Bela; Dhevani, Apria Audya; Ananda, Anugrah
Jurnal Pengabdian Masyarakat Bangsa Vol. 3 No. 10 (2025): Desember
Publisher : Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/jpmba.v3i10.3516

Abstract

Stunting disebabkan oleh kurangnya asupan gizi secara kronis, terutama selama periode 1.000 hari pertama kehidupan (HPK), yang berdampak pada terganggunya pertumbuhan fisik dan perkembangan kognitif anak. Salah satu upaya pencegahan stunting yang dapat dilakukan adalah dengan memanfaatkan bahan pangan lokal bergizi tinggi, seperti labu kuning (Cucurbita moschata Duch.) yang mengandung beta-karoten, vitamin A, C, serat, dan mineral. Labu kuning memiliki potensi sebagai bahan makanan fungsional, dalam hal pembuatan MPASI. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pengetahuan dan keterampilan masyarakat dalam pencegahan stunting melalui edukasi gizi dan pelatihan pengolahan labu kuning menjadi cheesecake sehat. Kegiatan dilaksanakan pada tanggal 2 Juni 2025 di Posyandu Kemuning, Kelurahan Sambutan, Kota Samarinda, dengan melibatkan 15 peserta yang terdiri dari kader posyandu, ibu dan balita. Metode yang digunakan meliputi penyuluhan interaktif, demonstrasi memasak, serta evaluasi melalui kuesioner. Hasil pengabdian menunjukkan peningkatan pemahaman peserta terhadap kondisi stunting, 75% peserta berada dalam kategori baik, 22% cukup, dan 3% kurang. Penyampaian materi secara praktis dan penggunaan media edukatif yang menarik dinilai efektif dalam meningkatkan keterlibatan peserta. Program ini membuktikan bahwa integrasi edukasi gizi dengan praktik pengolahan pangan lokal dapat menjadi strategi efektif dalam pencegahan stunting.
POTENSI ANTIBAKTERI EKSTRAK ETANOL DAUN SELUTUI PUKA (Tabernaemontana macrocarpa Jack.) TERHADAP BAKTERI Streptococcus mutans DAN Porphyromonas gingivalis Sabatini, Sheila Dwi; Handayani, Fitri; Sundu, Reksi
Jurnal Riset Kefarmasian Indonesia Vol. 5 No. 2 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i2.372

Abstract

The Dayak people in West Kutai, East Kalimantan use selutui puka leaves for the treatment of toothache and canker sores. Bacteria that often cause infections in the oral cavity are Streptococcus mutans and Porphyromonas gingivalis. The aim of this study was to determine the activity of the ethanol extract of selutui puka leaves as an antibacterial against Streptococcus mutans and Porphyromonas gingivalis. The research phase involved collecting samples, plant determination, preparing simplicia, preparing extracts and testing antibacterial activity using the paper disc diffusion method with extract concentrations of 15%, 30% and 45%, DMSO negative control 1%, positive control Ciprofloxacin 0.1%. The results showed that the average diameter of the inhibition zone for Streptococcus mutans at an extract concentration of 15% was 17.70 mm (strong), 30% was 19.43 mm (strong), and 45% was 23.60 mm (very strong). ) and against Porphyromonas gingivalis bacteria at an extract concentration of 15% of 17.43 mm (strong), 30% of 23.33 mm (very strong), and 45% of 26.03 mm (very strong).
KARAKTERISASI DAN SKRINING FITOKIMIA BUAH LABU KUNING (Cucurbita moschata Duch.) Budiman, Hariyadi; Supriningrum, Risa; Sundu, Reksi
Jurnal Riset Kefarmasian Indonesia Vol. 6 No. 1 (2024): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v6i1.420

Abstract

Pumpkin (Cucurbita moschata Duch.) is one of the plants that contain carotenoids, water-soluble vitamins, phenolics, flavonoids polysaccharides, mineral salts. Pumpkin is a vegetable that has many health benefits. Empirically, the pulp is used to treat diabetes, hypertension, tumors, immunomodulators and antibacterials. The benefits of a natural material with medicinal properties need to be proven scientifically through research. As a first step, characterization of simplisia and ethanol extract of pumpkin fruit and secondary metabolite content were carried out.  This study aims to determine the characteristics of simplisia and pumpkin fruit flesh extract and its secondary metabolite content. Characterization includes specific and non-specific parameters. Pumpkin fruit was extracted by maceration with 70% ethanol and obtained an extract yield of 29.68%. Specific characterization results include organoleptic observations in the form of thick blackish brown extract, bitter taste, and distinctive smell. Organoleptic simplicia simplicial piece, odorless, yellow, and bitter taste. The average level of soluble compounds in water extract is 47.33% and simplisia is 22%, while the average soluble compound in ethanol extract is 51.77% and simplisia is 31.33%. Non-specific characterization results include the average total ash content of extracts of 6.52% and simplisia of 8.33%, acid insoluble ash content test averaged 0.31% extracts and 0.22% simplisia. The average water content was 17.55%. The average specific gravity of the extract was 1.02 g/mL and the results of the total microbial contamination in the extract were 4.2 × 103 colonies/g and simplisia were 4.6 x 103 and the yeast mold number in the extract was 1.3 × 102 colonies/g and simplisia was 1.7 × 102 colonies/g. Pumpkin fruit extract and simplisia contain secondary metabolites including alkaloids, flavonoids, saponins, and terpenoids.
FORMULASI MASKER GEL PEEL OFF EKSTRAK BUNGA TELANG (Clitoria ternatea L.) SEBAGAI ANTIOKSIDAN ALAMI Aulia Rahmi Azizah; Rasidah, Ananda Imroatur; Wilujeng, Firdianty Lestari; Piya, Nor; Yuliani, Siska Dwi; Adhila, Ghina; Sundu, Reksi
Jurnal Riset Kefarmasian Indonesia Vol. 6 No. 1 (2024): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v6i1.477

Abstract

Natural ingredients containing antioxidant compounds can be made in the form of a peel-off gel mask which can help care for facial skin. Butterfly pea flowers (Clitoria ternatea L.) contain flavonoid anthocyanin compounds which can break the chain reaction of free radicals. The aim of this research is to determine the antioxidant activity of butterfly pea flower extract and the preparation of butterfly pea peel off gel mask. The peel off gel mask formulation uses butterfly pea flower extract with a concentration of 5%. Testing for antioxidant activity uses the DPPH method. Physical characteristics assessment includes organoleptic tests, homogeneity observations, spreadability tests, viscosity tests, drying time tests, and preparation pH tests. Based on the research results, the IC50 value of telang flower extract is 43.68 ppm in the very strong category and the IC50 value of the peel-off gel mask preparation is 307.71 ppm in the inactive category. This research shows that the ethanol extract of butterfly pea flowers has potential as a natural antioxidant.
PENETAPAN KADAR FENOL TOTAL EKSTRAK ETANOL RIMPANG TEMU PUTIH (Curcuma zedoaria (Christm.) Roscoe) DENGAN PERBEDAAN KONSENTRASI PELARUT Maulida, Mielsya; Nurhasnawati, Henny; Sundu, Reksi
Jurnal Riset Kefarmasian Indonesia Vol. 7 No. 1 (2025): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v7i1.543

Abstract

White Temu (Curcuma zedoaria (Berg.) Roscoe) has an actoxidant activity because it contains phenolic compounds. Phenolic compounds are aromatic compounds with a structure derived from benzene so that they have aromatic rings and the presence of one or more hydroxyl (OH) groups. This study aims to determine the total phenol content of white rhizome ethanol extract with the difference in solvent concentration using UV-Vis spectrophotometry. The research conducted is an experimental research. The results showed that the rhizome of white temu contained secondary metabolite compounds in the form of phenolics, alkaloids, flavonoids, saponins, and terpenoids. Based on the results of determining the total phenol content of white temu extract with a difference in ethanol solvent concentrations of 30%, 50%, and 70%, the levels were 23.4477±0.9827 mg GAE/g, 32.2464±1.3022 mg GAE/g, and 51.6880±0.4948 mg GAE/g. The results of statistical analysis obtained normal and homogeneous data so that a one-way anova test with p value results was used(0.00) < (0.05) so it can be concluded that there is a significant difference in the total phenol levels of the three samples.
PENETAPAN KADAR FENOLIK TOTAL FRAKSI POLR DAN NONPOLAR DAUN RAMBAI LAUT (Sonneratia caseolaris L.) DENGAN METODE SPEKTROFOTOMETRI UV-Vis Jubaidah, Siti; Sundu, Reksi; Sabriningsih, Nur
Jurnal Riset Kefarmasian Indonesia Vol. 1 No. 2 (2019): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v1i2.23

Abstract

Rambai laut (Soneratia caseolaris L.) is a type of tree that grows in riverbank swamps or mangrove forests which contains one of the secondary metabolites in the form of phenolic compounds. The purpose of this study was to determine the total phenolic content of polar and nonpolar fractions of sea rambai leaves using UV-Vis spectrophotometry method. Research conducted is non-experimental. The stages of the study included the determination of plants, sampling, making samples, making extracts, determining the water content of extracts, fractionation using polar and nonpolar fractions, phytochemical screening test of ethanol extract and fractionation results and determination of total phenolic levels by UV-Vis spectrophotometry. The results showed that rambai laut leaf in polar fraction had a total phenolic content of 213.49 ± 1.2227 mg GAE / g, which means that in each gram the polar fraction is equivalent to 213.49 mg of gallic acid, whereas in the nonpolar fraction of rambai laut leaves is obtained 55.79 ± 1.0809 mg GAE / g which means that in each gram the nonpolar fraction is equivalent to 55.79 mg of gallic acid. Total phenolic content is greater in the polar fraction.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK KULIT BATANG SEKILANG (Embelia borneensis Scheff) TERHADAP BAKTERI Escherichia coli DAN Staphylococcus aureus MENGGUNAKAN METODE DISC DIFFUSION Goetie, Inayah Herman; Sundu, Reksi; Supriningrum, Risa
Jurnal Riset Kefarmasian Indonesia Vol. 4 No. 2 (2022): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v4i2.260

Abstract

Sekilang is one of the plants in North Kalimantan and is found in the Ampan Ibau Forest. This plant is empirically used by the people of Long Temuyat Village as a poison from natural ingredients to catch fish and as a leech repellent. The content of active compounds in sekilang bark extract include alkaloids, tannins, saponins, flavonoids. These compounds have the potential as antibacterial, so it is necessary to test the antibacterial activity. The purpose of this study was to determine the antibacterial activity of the sekilang bark extract against Escherichia coli and Staphylococcus aureus bacteria. The research phase included plant determination, sample collection, maceration extraction, and antibacterial activity test using the disc diffusion method with extract concentrations of 20%, 30%, and 40%. The results showed that the ethanol extract of the bark of sekilang has the potential to inhibit bacterial growth. The antibacterial activity of the bark extract of the cruciferous plant against Escherichia coli bacteria at concentrations of 20%, 30% and 40%, respectively, was 5.9 mm, 6.7 mm and 5.9 mm. Meanwhile, the activity of the bark extract against Staphylococcus aureus at concentrations of 20%, 30% and 40%, respectively, was 7.6 mm, 6.8 mm and 8.0 mm. The antibacterial activity of the bark extract against both bacteria was included in the moderate criteria.
Co-Authors ., Sapri Adhila, Ghina Ameliora Dwi Astani Ananda, Anugrah Andi Wijaya Aulia Rahmi Azizah Budiman, Hariyadi Daniel Happy Putra Dawia Dawia Dawia, Dawia Dhevani, Apria Audya Dwi Setyawati Eka Kumalasari Eka Siswanto Syamsul Fitri Handayani Fitri Handayani Fitri Handayani Goetie, Inayah Herman Henny Nurhasnawati Henriko Nober Karapa Inayah Herman Goetie Karapa, Henriko Nober Maulida, Mielsya Milasari, Novi Mismawati, Andi Nabila, Annisa Bela Namira, Nadine Anastasya Putri Nathalia, Nyda Nurul Fatimah Nurul Fatimah Nurul Fatimah Piya, Nor Qarriy ‘Aina Urfiyya Rachman, Nadya Rahmawati Rachmanissa, Nadya Rakhmadhan Niah Rasidah, Ananda Imroatur Rena Handayani Alfian Ria Mareta Sari Rio Adi Saputra Risa Supriningrum Rismaul Wahdah Sabatini, Sheila Dwi Sabriningsih, Nur Sapri . sapri sapri Sapri Sapri Sheila Dwi Sabatini Siti Jubaidah, Siti Susilowati, Agustina Syamsiar, Syamsiar Triswanto Sentat Wilujeng, Firdianty Lestari Yuliani, Siska Dwi