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Perancangan Sistem Kesehatan dan Keselamatan Kerja (SMK3) di PT. SPINDO 1 William, Andy; Panjaitan, Togar W.S.
Jurnal Titra Vol 2, No 2 (2014)
Publisher : Jurnal Titra

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (78.005 KB)

Abstract

PT. SPINDO unit 1 is one of the big and famous company which produces steel pipe. Nowadays, PT. SPINDO 1 is willing to design health and management system (SMK 3) because of the high rate of the workplace accident for the year of 2013 that is 93 cases. Besides that, government rules stated that every company shall ensure the health and work safety of their employees within the scope of company or working area.The health and management system (SMK 3) design by PT. SPINDO appropriates with the actual conditions of the company and covers the HIRARC documents. Finally the result of the SMK 3 reached 62.69% which can be said “Good” according to the Government Regulation (PP) no 50 of 2012.
Peran Metformin sebagai Inhibitor Jaras Insulin-like Growth Factor-1 Receptor (IGF-1R), Epidermal Growth Factor Receptor (EGFR), dan Mammalian Target of Rapamycin (mTOR) pada Kemoterapi Kanker Paru Filbert Jayalie, Vito; William, Andy; -, Shelly; Irawan, Cosphiadi
Cermin Dunia Kedokteran Vol 43, No 6 (2016): Metabolik
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (853.143 KB) | DOI: 10.55175/cdk.v43i6.68

Abstract

Kanker paru adalah salah satu jenis kanker dengan prevalensi dan mortalitas yang tinggi di dunia. Beberapa studi klinis menunjukkan bahwa metformin dapat menurunkan angka mortalitas berbagai jenis kanker, termasuk kanker paru. Metformin dapat menghambat berbagai jaras persinyalan, seperti Insulin-like Growth Factor Receptor (IGF-1R), Epidermal Growth Factor Receptor (EGFR), dan mammalian Target of Rapamycin (mTOR), yang berperan dalam pertumbuhan dan proliferasi sel kanker. Selain itu, metformin juga memiliki efek sinergis dengan kemoterapi standar, yaitu dapat meningkatkan survival rate serta mengurangi dosis kemoterapi. Masih diperlukan penelitian lebih lanjut untuk mengetahui potensi kombinasinya dengan kemoterapi standar pada pengobatan kanker paru.
Perancangan Sistem Kesehatan dan Keselamatan Kerja (SMK3) di PT. SPINDO 1 Andy William; Togar W.S. Panjaitan
Jurnal Titra Vol 2, No 2 (2014)
Publisher : Jurnal Titra

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (179.591 KB)

Abstract

PT. SPINDO unit 1 is one of the big and famous company which produces steel pipe. Nowadays, PT. SPINDO 1 is willing to design health and management system (SMK 3) because of the high rate of the workplace accident for the year of 2013 that is 93 cases. Besides that, government rules stated that every company shall ensure the health and work safety of their employees within the scope of company or working area.The health and management system (SMK 3) design by PT. SPINDO appropriates with the actual conditions of the company and covers the HIRARC documents. Finally the result of the SMK 3 reached 62.69% which can be said “Good” according to the Government Regulation (PP) no 50 of 2012.
The Effectiveness of Giving Binahong (Anredera cordifolia) Leaf Extract on Granulation Tissue Thickness in Healing White Rat (Rattus novergicus) Cut Wounds Damayanti, Putri Raina; William, Andy; Wijaya, Gary
International Journal of Public Health Excellence (IJPHE) Vol. 3 No. 2 (2024): January-May
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v3i2.754

Abstract

Wounds result in loss of epithelial continuity with or without loss of underlying connective tissue. The dynamic and complex wound-healing process restores tissue integrity and balance. Medicinal plants in herbal medicine, namely Binahong, help heal wounds. This study tested binahong (Anredera cardifolia) leaf extract ointment on the thickness of granulation tissue in white rat (Rattus novergicus) incision wounds. Binahong leaf extract was applied at 15%, 25%, and 35%, then the wound was examined macroscopically and histopathologically. The type of research was a true experiment with a sample of 24 male Wistar rats, six per group, in four groups (control, treatment 1, treatment 2, treatment 3). The histopathological image of granulation tissue thickness shows that the P0 group (blue) has less collagen density. Treatment group 3 (P3) with 35% binahong leaf extract showed thick collagen. Analysis of the Shapiro-Wilk normality test and significant paired t-test values greater than p>0.05 for all groups. The Shapiro-Wilk normality test shows that the data is regularly distributed. Paired T-test showed significant differences in incision wound healing between groups (p-value <0.05). The research concludes that binahong leaf extract has antiseptic, antibacterial, and ascorbic acid properties and protects against oxidation, so it is helpful for wound healing.
Factors contributing to weight gain among students during the COVID-19 pandemic Marpaung, Jelentika; Marlinang, Putri; Siagian, Masryna; Bangun, Andreas Xaverio; Lister, Gilbert; Deseva, Frisca Gemmi; William, Andy
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6582

Abstract

Weight gain among students during the COVID-19 pandemic was largely attributed to lifestyle changes, including diet, sleep patterns, decreased physical activity, and increased gadget use. This study aimed to identify the factors influencing weight gain in students at SMKN 10 Medan. A quantitative methodology was employed, utilizing a cross-sectional approach. The study population consisted of all students at SMKN 10 Medan, totaling 1,108 individuals. A sample of 294 students was selected using a random sampling technique. Data analysis was conducted using the chi-square test and logistic regression. The results indicated that all variables were significantly related to student weight gain during the COVID-19 pandemic, with p-values for physical activity (p=0.036), breakfast habits (p=0.042), snacking habits (p=0.001), sleep patterns (p=0.001), and gadget use (p=0.001). The most influential factors contributing to student weight gain were identified as snacking habits and sleep patterns, which exhibited the lowest significance values. It can be concluded that snacking habits and sleep patterns are the predominant factors associated with weight gain among students at SMKN 10 Medan during the COVID-19 pandemic.
Factors contributing to weight gain among students during the COVID-19 pandemic Marpaung, Jelentika; Marlinang, Putri; Siagian, Masryna; Bangun, Andreas Xaverio; Lister, Gilbert; Deseva, Frisca Gemmi; William, Andy
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6582

Abstract

Weight gain among students during the COVID-19 pandemic was largely attributed to lifestyle changes, including diet, sleep patterns, decreased physical activity, and increased gadget use. This study aimed to identify the factors influencing weight gain in students at SMKN 10 Medan. A quantitative methodology was employed, utilizing a cross-sectional approach. The study population consisted of all students at SMKN 10 Medan, totaling 1,108 individuals. A sample of 294 students was selected using a random sampling technique. Data analysis was conducted using the chi-square test and logistic regression. The results indicated that all variables were significantly related to student weight gain during the COVID-19 pandemic, with p-values for physical activity (p=0.036), breakfast habits (p=0.042), snacking habits (p=0.001), sleep patterns (p=0.001), and gadget use (p=0.001). The most influential factors contributing to student weight gain were identified as snacking habits and sleep patterns, which exhibited the lowest significance values. It can be concluded that snacking habits and sleep patterns are the predominant factors associated with weight gain among students at SMKN 10 Medan during the COVID-19 pandemic.
The Effectiveness of Giving Binahong (Anredera cordifolia) Leaf Extract on Granulation Tissue Thickness in Healing White Rat (Rattus novergicus) Cut Wounds Damayanti, Putri Raina; William, Andy; Wijaya, Gary
International Journal of Public Health Excellence (IJPHE) Vol. 3 No. 2 (2024): January-May
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v3i2.754

Abstract

Wounds result in loss of epithelial continuity with or without loss of underlying connective tissue. The dynamic and complex wound-healing process restores tissue integrity and balance. Medicinal plants in herbal medicine, namely Binahong, help heal wounds. This study tested binahong (Anredera cardifolia) leaf extract ointment on the thickness of granulation tissue in white rat (Rattus novergicus) incision wounds. Binahong leaf extract was applied at 15%, 25%, and 35%, then the wound was examined macroscopically and histopathologically. The type of research was a true experiment with a sample of 24 male Wistar rats, six per group, in four groups (control, treatment 1, treatment 2, treatment 3). The histopathological image of granulation tissue thickness shows that the P0 group (blue) has less collagen density. Treatment group 3 (P3) with 35% binahong leaf extract showed thick collagen. Analysis of the Shapiro-Wilk normality test and significant paired t-test values greater than p>0.05 for all groups. The Shapiro-Wilk normality test shows that the data is regularly distributed. Paired T-test showed significant differences in incision wound healing between groups (p-value <0.05). The research concludes that binahong leaf extract has antiseptic, antibacterial, and ascorbic acid properties and protects against oxidation, so it is helpful for wound healing.