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All Journal Global Medical and Health Communication Medical Laboratory Technology Journal Meditory : The Journal of Medical Laboratory Jurnal Kesehatan Manarang The Indonesian Journal of Infectious Diseases Jurnal Ilmu dan Teknologi Kesehatan Jurnal Riset Kesehatan Poltekkes Depkes Bandung Medica Hospitalia Health Information : Jurnal Penelitian Health Media Muhammadiyah Journal of Midwifery (MyJM) Ahmar Metastasis Health Journal (AMHJ) Inovasi Jurnal Pengabdian Masyarakat (IJPM) Genitri: Jurnal Pengabdian Masyarakat Bidang Kesehatan Media Penelitian dan Pengembangan Kesehatan Jurnal Info Kesehatan
Rizana Fajrunni’mah
Poltekkes Kemenkes Jakarta III
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences

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Correlation of C-Reactive Protein (CRP) Levels with D-Dimer Levels in COVID-19 Patients Choirunisa, Churiyyah Eka; Widhyasih, Retno Martini; Fajrunni’mah, Rizana
jitek Vol 11 No 1 (2023): September 2023
Publisher : Poltekkes Kemenkes Jakarta III

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32668/jitek.v11i1.1317

Abstract

Coronavirus disease 2019 is caused by SARS-CoV-2 infection. COVID-19 causes increased levels of proinflammatory cytokines, so CRP and d-dimer levels in COVID-19 patients tend to increase. This study aimed to analyze the correlation between C-Reactive Protein (CRP) levels and D-dimer levels in COVID-19 patients. This research method is analytic observational by using cross-sectional secondary data. The population of this study were all COVID-19 inpatients at Budhi Asih Hospital, East Jakarta, with a sample of 338 patients and were taken by random sampling. The results of this study found that female and male COVID-19 patients had the same risk of being infected with female patients as much as 52,7% and male patients amounting to 47,3%. Most COVID-19 patients occurred at the age of ≥60 years, namely 32,2%. All patients, which is 100% patients had high CRP levels, with a mean of 76,06 mg/L. As for D-dimer levels, 47,9% of patients had normal D-dimer levels and 52,1% had high D-dimer levels with an average of 721,48 ng/mL. The results of the Spearman's correlation test obtained a p value = 0,000, so it can be seen that there is a correlation between C-Reactive Protein (CRP) levels and D-dimer levels in COVID-19 patients with a correlation strength of 0,300 (medium). An increase in CRP levels followed by an increase in D-dimer levels but evaluation of other laboratory examination parameters also needs to be considered.
Penyuluhan dan Pemeriksaan Kristal Kalsium Oksalat untuk Pencegahan Gangguan Saluran Kemih pada Warga Desa Ligarmukti, Kabupaten Bogor, Jawa Barat Purwanti, Angki; Lestari, Diah; Fajrunni'mah, Rizana
Inovasi Jurnal Pengabdian Masyarakat Vol 3 No 3 (2025): IJPM - Desember 2025
Publisher : CV Firmos

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54082/ijpm.944

Abstract

Air warga Desa Ligarmukti yang digunakan rutin untuk keperluan domestik bersifat sadah. Akibatnya warga mengalami gangguan kesehatan seperti nyeri pinggang, sulit berkemih dan anyang-anyangan. Tujuan pengabdian melakukan identifikasi kristal kalsium oksalat pada urin warga dan meningkatkan pengetahuan warga agar dapat meminimalkan adanya kristal kalsium oksalat dalam urin. Peningkatan pengetahuan dilakukan melalui ceramah dibantu media leaflet serta poster dan pemeriksaan kristal kalsium oksalat dengan metode mikroskopis.  Evaluasi dilihat dari rerata persentase kenaikan skor pre dan post test. Hasil identifikasi negatif dan positif kristal kalsium oksalat sebanyak 40 (62,5%) orang dan 24 (37,5%) orang dengan 17 orang positif satu dan 7 orang positif dua. Rerata skor pre test di RT 06, RT 11, RT 12 adalah 1,8, 1,4, 2,27. Rerata skor post test di ketiga RT adalah 6,6, 5,2, 6,7.  Persentase kenaikan skor pre dan post test di ketiga RT adalah 72,7%, 73,1%, 66,1%. Dari kegiatan pengabdian ini diketahui terdapat gangguan urinasi warga desa akibat pembentukan kristal kalsium oksalat. Penyuluhan pada pengadian ini meningkatkan pengetahuan warga desa untuk meminimalkan adanya kristal kalsium oksalat dalam saluran urin dengan cara mengurangi konsumsi makanan dan minuman tinggi oksalat serta konsumsi rebusan TOGA yang dapat meluruhkan kristal kalsium oksalat.
Status Kadar Antibodi Spike Receptor Binding Domain setelah Vaksinasi Kedua menggunakan Vaksin Inaktivasi Fajrunni'mah, Rizana; Purwanti, Angki; Khasanah, Furaida; Setiawan, Budi
Health Information : Jurnal Penelitian Vol 14 No 2 (2022): Juli-Desember
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36990/hijp.v14i2.636

Abstract

Coronavirus Disease 2019 (COVID-19) adalah penyakit menular yang disebabkan oleh Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) yang berlangsung cukup cepat dan menyebar ke berbagai negara dalam waktu singkat. Vaksinasi merupakan salah satu upaya menanggulangi pandemi COVID-19. Salah satu jenis vaksin yang saat ini digunakan adalah vaksin dengan jenis inaktivasi. Tujuan penelitian ini untuk mengetahui kadar antibodi setelah vaksinasi kedua menggunakan jenis vaksin inaktivasi sebelum diberikan vaksinasi lanjutan ketiga, dan faktor-faktor yang mempengaruhinya. Penelitian menggunakan metode observasional yang berlokasi di Poltekkes Kemenkes Jakarta III selama Februari 2022, jumlah sampel sebanyak 33 orang. Pengukuran kadar antibodi S-RBD (receptor binding domain) SARS-CoV-2 kuantitatif menggunakan metode ECLIA dengan alat Cobas e-411. Setelah penelitian, kadar antibodi 100% reaktif dengan rentang yang bervariasi, kelompok tinggi (>250 U/mL) sebanyak 84,8%, menengah (117-250 U/mL) sebanyak 6,1%, dan rendah (<117 U/mL) sebanyak 9,1%. Terdapat hubungan antara indeks massa tubuh dengan kadar antibodi (p=0,046). Tidak terdapat hubungan antara jenis kelamin, usia, jarak waktu setelah vaksin kedua, riwayat COVID-19, dan riwayat komorbid dengan kadar antibodi. Vaksin COVID-19 jenis inaktivasi menginduksi respons antibodi kuat yang masih bertahan sebelum dilakukannya vaksinasi lanjutan ketiga.
Relationship between Procalcitonin Levels (PCT) and Disease Severity in Hospitalized Patients Confirmed Positive for COVID-19 Fajrunni'mah, Rizana; Rada, Fransiska; Widhyasih, Retno Martini
JURNAL INFO KESEHATAN Vol 20 No 1 (2022): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol20.Iss1.638

Abstract

Coronavirus Disease 2019 (COVID-19) is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). This disease attacks the respiratory tract and spreads rapidly almost throughout the world, hence, WHO has declared COVID-19 as a global pandemic. The presence of inflammation and bacterial co-infection in COVID-19 hospitalized patients can increase procalcitonin (PCT) levels as a biomarker of inflammation. Elevated PCT levels are also associated with disease severity. The objective of this study is to determine the relationship between PCT levels and disease severity in hospitalized patients who are confirmed positive for COVID-19. This research method is analytic observational with cross sectional design. The sample is in the form of medical record data for 180 COVID-19 patients who are hospitalized at Bhayangkara Tk. I Raden Said Sukanto Hospital, Jakarta for the period July-December 2020. The relationship between PCT levels and disease severity was statistically analyzed using the Chi Square test. The results of this study were 109 (60.6%) men and 71 (39.4%) women with the highest age group being 46-59 years. The average PCT level was 10.38 ng/mL with the lowest level of 0.01 ng/mL and the highest level of 282.00 ng/mL. PCT levels <0.5 ng/mL were discovered in 111 patients (61.7%) and PCT levels 0.5 ng/mL in 69 patients (38.3%). The severity of disease in mild-moderate illness was 87 patients (48.4%), severe was 35 patients (19.4%), and critical was 58 patients (32.2%). The Chi Square test showed that there was a relationship between PCT levels and disease severity in COVID-19 patients (p = 0.000). The higher the PCT level, the higher the severity of the disease, thus, PCT can be used as an indicator to see the severity of the disease.
Co-Authors Al’fira Gita Islami Angki Purwanti Angki Purwanti Angki Purwanti Angki Purwanti, Angki Anisah Wulansari Anita Suswanti Agustina Apriliani, Isnawati Bagya Mujianto Budi Setiawan Choirunisa, Churiyyah Eka Dewi Astuti Dewi Astuti Diah Lestari Diah Lestari, Diah Djajaningrat, Husjain Eva Ayu Maharani Farida Murtiani Febriyana, Niniek Dwi Furaida Khasanah, Furaida Islami, Yasyavia Hatifah Karningsih Karningsih Kunti Wijiarti Lyana Setiawan Mega Mirawati Michael Alfian Grey Mita Puspita Sari Murtiani, Farida Prasetyorini, Tri Purwanti , Angki Rada, Fransiska Retno Martini Widhyasih Rika Erviani Sriyanto Sriyato Suci Dwi Rahmadhanti Syifa Amelia Nadayang Warida Warida Widhyasih, Retno Martini Widiantari, Aninda Dinar