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Solasodine and Gosipol Effectivity as a Male Contraception Inhibit LH Expression and Spermatogenesis in Rat Wulansari, Desi; Oktanella, Yudit; Hendrawan, Viski Fitri; Agustina, Galuh Chandra
Veterinary Biomedical and Clinical Journal Vol. 1 No. 2 (2019)
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (364.671 KB) | DOI: 10.21776/ub.VetBioClinJ.2019.001.02.7

Abstract

Rabies related to increasing canine population in Bali. Uncontrolled wild animal populations caused disease transmission from animal to human. Various attempt at population control are carried out such as the use of natural contraception. Some compounds are known to have potential as antifertility are solasodine and gosipol. Solasodine is known have an antifertility affect. Gosipol, fenolic compound in Ceiba pentandra, inhibits spermatogenesis, reduce sperm concentration, motility and viability. This research aims to compare effectiveness of terong cepoka and Ceiba pentandra as antifertility. This research was conducted at Mei-November 2018. Eight-teen rats were used in this study and divided into three groups: control, P1 extract Solanum torvum 1g/kg BW and P2 extract Ceiba pentandra 0,1g/kg BW PO. Rats were treated with extract for 10 days and euthanazed at day 11. Testis were collected for histopathology using HE staining to observe spermatogenesis and using immunohistochemistry to observe LH expression. The result are analyzed using one way ANOVA P<0.05. the result show that extract solanum torvum 1g/kg BW and ceiba pentandra 0,1g/kgBW cannot reduce spermatogenesis and LH expression. This study used crude extract which still consist any other compound like antioxidant. Future study we need use isolated and pure solasodine and gosipol.
Mapping of Learning Guidance Competencies in Dealing with Digital Learning Irwan, Mahfuzi; Lubis, Putri Ramadhani; Nasution, Ikhwanu Sopia; Wulansari, Desi; Siahaan, Sisilia Brigita; Pasaribu, Dhieta Naiya Arthameyvia
Journal of Social Science and Education Research Vol. 1 No. 8 (2024): Journal of Social Science and Education Research
Publisher : Raudhah Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59613/zhzyas25

Abstract

Industrial Revolution 4.0 is a major phenomenon that has changed the global landscape in various aspects of life, including education. These changes have a significant impact on the competencies of learning teachers, who must adapt quickly to meet the demands of this digital era. In the Industrial Revolution 4.0, the role of tutors has changed to become more than just a teacher. They must be the main drivers of project-based and collaborative learning, where learning citizens can work in teams to develop projects that are relevant to the real world. Learning tutors must encourage creativity, courage to think, and the ability to solve students' problems. This change requires learning teachers to explore the spirit of exploration and innovation within themselves, so that they can inspire students to do the same. To face revolution 4.0, the author intends to design the competencies that learning teachers must have, for example the professionalism competencies of learning teachers. The research method that researchers use is a qualitative approach and the research data collection that will be used is a questionnaire. It is hoped that the professional competencies possessed by the learning tutors can improve the teaching abilities of the learning tutors and with the professional competencies they have, it is hoped that the learning tutors can face the industrial revolution 4.0.
The Development of Interactive Picture Card Media with QR Code to Improve IPAS Learning Outcomes Wulansari, Desi; Tyas, Dewi Nilam
Jurnal Prima Edukasia Vol. 13 No. 2 (2025): May 2025
Publisher : Asosiasi Dosen PGSD dan Dikdas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21831/jpe.v13i2.84474

Abstract

One element that encourages increased student focus and makes it easier to understand the subject matter is learning media. This study aims to create and evaluate interactive picture card media with QR codes to enhance grade IV students' learning results. Research and Development (R&D), which is modified into nine phases until the final product revision, is the method used in this study. The research subjects are teachers, students, media specialists, and subject matter specialists. Data collection was conducted through observation, surveys, interviews, and documentation. The t-test, n-gain, and normality tests are the data analysis methods used in this investigation. The design validation results get very feasible criteria from media experts (92.28%) and material experts (92.18%). The results of the classroom teacher response were 93.75%, and the student response was 94.27%, which are feasible criteria. The significant effectiveness test using the t-test is 0.000, which indicates that Ha is accepted while Ho is rejected. The n-gain calculation is 0.6915 medium criteria. Thus, the interactive picture card media with the QR Code that has been developed is very feasible and effective for improving learning outcomes. These findings contribute to the development of innovative learning media that can enhance student learning outcomes and offer new alternatives for teachers in delivering lesson materials, especially at the elementary school level.
IDENTIFIKASI GROWTH DIFFERENTIATION FACTOR-9 (GDF-9) DARI MATURASI IN VITRO OOSIT SAPI DENGAN TEKNIK IMUNOSITOKIMIA w, Widjiati; Wulansari, Desi; w, Wurlina; Widjaja, Ngakan Made Rai
Jurnal Kedokteran Hewan Vol 5, No 2 (2011): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v5i2.356

Abstract

Penelitian ini bertujuan mengindentifikasi GDF-9 di dalam oosit yang berasal dari preantral folikel sapi yang dimatangkan secara in vitro. Penelitian ini menggunakan metode imunositokimia ikatan antara molekul avidin dan biotin yang terkandung dalam antibodi sekunder bentuk kompleks avidin-biotin. Ovarium sapi diambil dari rumah potong hewan (RPH) Pegirian Surabaya. Penelitian ini menggunakan 105 oosit matang yang berasal dari 62 ovarium. Hasil imunositokimia menunjukkan bahwa 77,14% GDF-9 teridentifikasi.