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Increasing Artemisinin Content on Artemisia Plants Through Endophytic Bacteria Inoculation as An Effort to Support the Availability of Malaria Drugs : Peningkatan Kandungan Artemisinin pada Tanaman Artemisia Melalui Inokulasi Bakteri Endofit Sebagai Upaya Mendukung Ketersediaan Obat Malaria Yuliani, Farida; Nureida, Fadila Rona; Fairuzia, Fazat; Rosidah, Eva Hana; Nugroho, Agung Wahyu; Amiroh, Afifatul
Jurnal Tumbuhan Obat Indonesia Vol. 17 No. 1 (2024): July 2024
Publisher : Universitas Tidar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31002/jtoi.v17i1.1155

Abstract

In 2020, malaria cases worldwide increased from 219 million cases to 241 million cases with 627 thousand deaths. This creates problems in terms of the availability of malaria drugs. In addition, resistance to Plasmodium sp. against the commonly used malaria drug chloroquine is another problem. Therefore, in the treatment of malaria, combination-based treatment with artemisinin is highly recommended. However, there are obstacles in the production of artemisinin because its content in plants is relatively low. Therefore, this research aims to increase artemisinin content using endophytic bacteria. The method used is a factorial design with 2 factors, namely Accessions (Green & Purple) and endophytic bacteria concentration (0%, 1%, and 2%). Endophytic bacteria isolated from artemisinin plants were first cultured in a nutrient-rich medium to increase their population. Then, they were inoculated by spraying them twice a week for two months with each accession in each treatment combination. The results showed that inoculation with endophytic bacteria had the best concentration in increasing artemisinin content, namely 1% in green and purple Artemisia accessions. Artemisinin inoculation of 1% was able to increase artemisinin by 27.85% compared to control plants in green Artemisia and purple Artemisia accessions with an increase of 32.89% compared to control plants. The best concentration of endophytic bacteria in increasing artemisinin content is 1%.
Motivation Of Pregnant Women Regarding Breast Care At Tpmb Gayaman Village, Mojoanyar District, Mojokerto District Mail, Erfiani; Farida Yuliani; Fitria Edni Wari
Journal for Quality in Women's Health Vol. 8 No. 1 (2025): March
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/jqwh.v8i1.268

Abstract

Taking care of your breasts both during pregnancy and after giving birth will maintain the shape of your breasts and also facilitate the flow of breast milk. (Manuaba, 2010). The impact that arises if breast care is not carried out and breast care is only carried out after delivery, then the mother will experience problems such as breast milk not coming out, nipples not protruding, little milk production, breast infections, mastitis, and sore nipples. In this study, the aim was to determine the motivation of pregnant women regarding breast care at TPMB, Gayaman Village, Mojoanyar District, Mojokerto Regency. This research was conducted in this type of research is descriptive. The design in this research is survey The variables used in this research are Motivation of Pregnant Women Regarding Breast Care in TPMB Gayaman Village, Mojoanyar District, Mojokerto Regency.
Hubungan Pengetahuan Ibu Tentang ASI Eksklusif Dengan Pemberian MP ASI Sebelum Usia 6 Bulan Di Desa Gayaman Kecamatan Mojoanyar Kabupaten Mojokerto Farida Yuliani
MEDICA MAJAPAHIT Vol 6 No 1 (2014): Medica Majapahit
Publisher : Sekolah Tinggi Ilmu Kesehatan Majapahit Mojokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ASI eksklusif berperan untuk dalam pertumbuhan, perkembangan, serta kesehatan yang optimal bagi bayi. Selain itu ASI dapat pula meningkatkan IQ dan EQ anak. Namun upaya pemerintah dalam penggalakan ASI eksklusif di Indonesia masih menemukan banyak hambatan, diantaranya kurangnya pengetahuan masyarakat tentang pentingnya ASI eksklusif. Kurangnya pengetahuan menimbulkan anggapan anaknya akan kelaparan bila hanya diberi ASI, namun sebaliknya mereka beranggapan anaknya akan tidur nyenyak setelah diberi makan. Oleh sebab itu penelitian ini bertujuan untuk mengetahui hubungan pengetahuan ibu tentang ASI eksklusif dengan pemberian MP ASI sebelum usia 6 bulan. Jenis penelitian adalah analitik korelasional dengan metode cross sectional. Hipotesis yang diajukan adalah ada hubungan pengetahuan ibu tentang ASI eksklusif dengan pemberian MP ASI sebelum usia 6 bulan di Desa Gayaman Mojoanyar Mojokerto. Terdapat 2 variabel yaitu pengetahuan ibu tentang ASI eksklusif dan pemberian MP ASI sebelum usia 6 bulan. Tekhnik sampling yang digunakan adalah sampel jenuh, dengan 48 responden. Data dikumpulkan tanggal 7-19 Juni 2010 menggunakan kuesioner dan lembar observasi. Analisis data dengan uji wilcoxon signed ranks test. Hasil penelitian menunjukkan rata-rata responden berpengetahuan baik yaitu 27 responden (56.3%) dan rata-rata responden tidak memberikan MP ASI sebelum usia 6 bulan yaitu 28 responden (58.3%). Hasil uji statistik menunjukkan sig. (2 tailed) (0.000) < α (0.05). Maka H1diterima, artinya ada hubungan pengetahuan ibu tentang ASI eksklusif dengan pemberian MP ASI sebelum usia 6 bulan di Desa Gayaman kecamatan Mojoanyar Mojokerto. Pengetahuan tentang ASI eksklusif mempengaruhi pemberian MP ASI dini, pada pengetahuan baik akan mendorong ibu tidak memberikan MP ASI dini. Sebaliknya jika pengetahuan cukup dan kurang akan mendorong ibu memberikan MP ASI dini. Pengetahuan merupakan salah satu faktor yang mempengaruhi pemberian MP ASI sebelum usia 6 bulan. Diharapkan para ibu memberikan ASI eksklusif kepada bayinya dan meninggalkan tradisi memberikan makanan padat sebelum bayi berusia 6 bulan. Hal ini hendaknya didukung oleh tenaga kesehatan juga anggota keluarga lainnya.
Agronomic characteristics and radiosensitivity level of the Rubaru shallot irradiated by gamma rays Persada, Olfa; Fairuzia, Fazat; Yuliani, Farida; Arini, Nindya
Indonesian Journal of Agricultural Research Vol. 8 No. 3 (2025): InJAR, Vol. 8, No. 3, In Press
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/injar.v8i3.16838

Abstract

The Rubaru shallots are resistant to various abiotic and biotic stresses, such as high salinity and Fusarium wilt disease. However, this shallot was unable to flower even after flowering was induced by cold temperatures and increasing day length, as well as polyploidy methods. Therefore, efforts are needed to increase the genetic diversity of the Rubaru variety of shallots through the induction of physical mutations with gamma ray irradiation. This research aims to determine the agronomic characteristics and radiosensitivity level of the Rubaru shallot (Allium cepa L.) resulting from gamma-ray irradiation. The research used a Randomized Complete Block Design (RCBD) with one factor, namely the dose of gamma ray irradiation (G), which consists of 5 levels as follows: G0 (control), G1 (2 Gy), G2 (4 Gy), G3 (6 Gy), G4 (8 Gy). The gamma-ray irradiation treatment had a very significant effect on agronomic characteristics, namely plant length and number of leaves, number of bulbs per cluster, bulb diameter, bulb fresh weight per cluster, bulb dry weight per cluster, and weight of the largest bulb per cluster. Gamma irradiation treatment with a dose of 2 Gy produced the highest number of bulbs and bulb diameter, with the largest weight of < 3g. Meanwhile, a dose of 8 Gy had a real effect on all parameters in inhibiting the growth of the Rubaru shallot. The calculated lethal dose (LD50) value is 6.18 Gy.