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All Journal Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) INDONESIAN JOURNAL OF PHARMACY Jurnal Farmasi Sains dan Komunitas JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Indonesian Journal of Chemistry JPSCR : Journal of Pharmaceutical Science and Clinical Research Jurnal Ilmu Kefarmasian Indonesia JCPS (Journal of Current Pharmaceutical Sciences) Pharmaceutical Journal of Indonesia Jurnal Pengabdian Kesehatan Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang Journal of Fundamental and Applied Pharmaceutical Science Abdimas Altruis: Jurnal Pengabdian Kepada Masyarakat Jurnal Pengabdian Masyarakat Sehati Jurnal Medika: Medika Journal of Tropical Pharmacy and Chemistry
Sri Hartati Yuliani
Sanata Dharma University
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Dentistry Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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EDUKASI PEMBERIAN GIZI SEIMBANG UNTUK MENCEGAH STUNTING DI KECAMATAN WONOSARI, DAERAH ISTIMEWA YOGYAKARTA Putri, Dina Christin Ayuning; Yuliani, Sri Hartati; Gani, Michael Raharja; Adi, Antonius Iswara; Tasik, Sulistiana; Ani, Ni Wayan; Elliora, Greata; Chusien, Adhita Wicaksaneng Naya Brena; Lewier, Bryan Melianus Agustinus
Jurnal Pengabdian Masyarakat Sehati Vol. 3 No. 2 (2024): Desember
Publisher : Politeknik Medica Farma Husada Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33651/jpms.v3i2.683

Abstract

Angka stunting di Kecamatan Wonosari Daerah Istimewa Yogyakarta cukup tinggi. Upaya-upaya perlu dilakukan untuk menurunkan angka stunting hinga mencapai target yang ditetapkan pemerintah (14%). Kegiatan ini bertujuan untuk meningkatkan pengetahuan orang tua mengenai pola hidup sehat dan pemberian gizi seimbang bagi anak, untuk mencegah stunting. Kegiatan berupa penyuluhan dilakukan terhadap orangtua yang anaknya terindikasi stunting atau hampir stunting di wilayah Kecamatan Wonosari. Evaluasi dilakukan dengan wawancara dan pengisian kuesioner. Kegiatan diikuti oleh 38 orang tua yang bersedia hadir memenuhi undangan. Pengetahuan peserta tentang pola hidup sehat dan pemberian gizi seimbang sangat baik, yang ditunjukkan dengan (pengisian kuesioner) nilai rerata + simpangan baku sebesar 87,91 + 0,69.
Optimization of Glycerin and Sorbitol in Hand Sanitizer Cream with Centella asiatica (L.) Extract Novela, Yuven; Yuliani, Sri Hartati
Media Farmasi: Jurnal Ilmu Farmasi Vol. 21 No. 2: September 2024
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v21i2.25629

Abstract

The use of alcohol-based hand sanitizers can cause dry skin. Centella asiatica (L.) extract can be used as an alternative to alcohol because it contains triterpenoids, especially asiatic acid, potentially an antibacterial and inhibitor of the SARS-CoV-2 virus. Cream is a preparation that can moisturize and protect the skin. Glycerin and sorbitol are humectants often used in cream preparations and have a large percentage in the cream preparation's formula so that they can affect the physical properties of the cream. This study aims to obtain the optimum composition range of glycerin and sorbitol and determine the effect of glycerin and sorbitol as humectants on the physical properties and stability of the hand sanitizer cream with Centella asiatica (L.) extract. The composition optimization was done using a factorial design method on two factors and two levels using the Design Expert 13 (free trial) application. The data on the physical properties and stability of the cream were statistically analyzed using a two-way ANOVA test at a 95% confidence level. The results of qualitative phytochemistry screening showed that the extract contained triterpenoid. The average test of physical properties and stability of physical properties meet the desired criteria: cream type O/W, viscosity 120–170 dPa.s., spreadability of 5-7 cm, shift of spreadability, and shift of viscosity below 10%. The optimum area shows that the formulas F1, FB, and FAB meet the desired criteria.
Quality of Extemporaneous Preparation Containing Theophylline, Salbutamol Sulphate and Methylprednisolone Sri Hartati Yuliani; Bernadetta Karina Sekar Maheswari; Melynia Sintha Dewi; Michael Raharja Gani; Dina Christin Ayuning Putri
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 20, No 2 (2023)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.005316

Abstract

Capsule preparations containing theophylline, salbutamol sulfate, and methylprednisolone were frequently prescribed in a private hospital in Yogyakarta. Theophylline is a narrow therapeutic index drug. Extemporaneous preparation products that contain narrow therapeutic index drugs have to meet the quality requirement. This study aimed to evaluate the quality of the capsule preparations. The sample was taken from a private hospital in Yogyakarta. The samples were assessed for physical characteristics, content uniformity, and chemical stability during storage. The result found that the physical characteristics of the product were good. The coefficients of variance of the content uniformity percentage for theophylline, salbutamol sulfate, and methylprednisolone were 11.96%, 3.33%, and 45.74%, respectively. During 30 days of storage, the content of theophylline, salbutamol sulfate, and methylprednisolone decreased by 1.44%, 7.64%, and 15.7%, respectively. Capsule preparations containing theophylline, salbutamol sulfate, and methylprednisolone did not meet the quality requirement.
Na-CMC and glycerine optimization in Binahong leaf extract (Anredera cordifolia) liposome gel and its burn wound healing activity Immanuel, Handika; Branitasandini, Regina Epiphania Adhika; Branitasandini, Adhika; Arpan, Verdynant Augusto; Pebrianty, Sahara; Kerenhapukh, Miracle; Wardhani, Kresentia Ayu Kusuma; Yuliani, Sri Hartati
Pharmaciana Vol. 15 No. 1 (2025): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v15i1.30112

Abstract

Burns represent a critical global health issue, contributing to considerable morbidity and mortality rates, particularly within the Southeast Asian region. The administration of appropriate burn therapy is essential to prevent infections and promote effective wound healing. The binahong leaf (Anredera cordifolia) represents a highly promising natural substance for burn therapy, attributed to its ursolic acid content, which is acknowledged for its wound healing properties. However, the limitation caused by its limited solubility and bioavailibility requires the use of nanoparticle technology, such as liposomes, to enhance its efficacy. The aim of this research was to determine an optimal formulation of gel containing liposome-encapsulated binahong leaf extract, with the goal of promoting burn wound healing and examining its in vivo wound healing activity. Histological analysis was employed to provide additional insights into the activity of the gel. The formulation was assessed through a factorial design, exploring various amounts of Na-CMC utilized as a gelling agent alongside glycerine employed as a humectant. The results were subsequently analyzed utilizing Design Expert v13 software. The gel’s viscosity, spreadability, and uniformity were assessed. Na-CMC increased viscosity while reducing spreadability, whereas glycerine had the opposite effect. The optimal formulation contained 2.78–4 g Na-CMC and 5–10 g glycerine. Statistical validation confirmed the model's accuracy. In vivo studies demonstrated that liposomal binahong gel significantly accelerated burn wound healing compared to controls. The results suggest that 10% binahong liposomal gel is a promising alternative for burn treatment.
Stability Model Prediction Using the Response Surface Approach to Assess the Outcomes of Vitamin B12 Injection Post-Market Sampling Yulia, Yulia; Yuliani, Sri Hartati
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 21, No 2 (2024)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.007779

Abstract

B12 injections are one of the most widely used vitamins in Indonesia. The nature of vitamin B12, which is easily degraded by environmental factors, has been widely reported. This research aimed to determine the effect of stability optimization model predictions with post-market sampling of vitamin B12 injection preparations by considering the variables of temperature, humidity, and distribution time. Factorial design was used to determine the stability optimization model. Validation of the analysis method using ultraviolet (UV) spectrophotometry showed valid results for testing. Stable product outcomes were seen during the research period based on the results of post-market sampling, optimization of stability conditions by evaluating pH parameters, and content determination. Post-market sampling data showed a pH decrease of 3.46% in the Palembang distribution area and an increase in pH of 4.54% and 5.33% in the Cirebon and Denpasar distribution areas. In the Palembang distribution area, the content of cyanocobalamin decreased by 0.90%, while in the Cirebon distribution area, it decreased by 0.94%. A paired t test for statistical analysis was used to determine the significance of the model. The results obtained show that there was no significant difference between the prediction model and the results of post-market sampling (p-values of 0.065 and 0.491) or H0 received
Pelatihan Pemanfaatan Bahan Alam Dalam Sediaan Perawatan Kulit Putri, Dina Christin Ayuning; Yuliani, Sri Hartati; Dwiastuti, Rini; Immanuel, Handika
Jurnal Pengabdian Kesehatan Vol 8, No 3 (2025): Jurnal Pengabdian Kesehatan
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LPPM) STIKES Cendekia Utama Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31596/jpk.v8i3.402

Abstract

Saat ini, tren penggunaan sediaan perawatan kulit (skin care) semakin meningkat. Pentingnya penggunaan sediaan perawatan kulit perlu untuk dipahami oleh remaja-remaja. Indonesia sebagai salah satu negara dengan sumber daya alam yang tinggi juga berpotensi dalam menghasilkan sediaan perawatan kulit berbhaan alam. Kegiatan pengabdian ini bertujuan untuk meningkatkan pemahaman remaja tentang pemanfaatan bahan alam dalam sediaan perawatan kulit. Kegiatan pengabdian dilakukan dengan pemberian materi berupa presentasi dan pemutaran video tutorial pembuatan body scrub dari bahan alam. Tingkat pemahaman peserta diuji melalui pretes dan postes. Hasil tes diuji dengan uji T 1 arah untuk sampel berpasangan. Kegiatan terlaksana dengan baik. Jumlah peserta yang hadir adalah sebanyak 88 orang siswa-siswi sekolah menengah dan mahasiswa-mahasiswi. Paparan materi dapat diterima dengan baik dibuktikan dengan meningkatnya rerata nilai pretest dan post test. Hasil uji T juga menunjukkan adanya perbedaan signifikan antara kedua pengujian tersebut, sehingga dapat disimpulkan bahwa peserta mengalami peningkatan pemanfaatan bahan alam dalam sediaan perawatan kulit.
Preparation and Characterization of Binahong (Anredera cordifolia) Leaf Extract Transfersome Wound-Healing Gel Immanuel, Handika; Yuliani, Sri Hartati; Dwiastuti, Rini; Nugraha, Alvin Arya; Limianty, Angela; Annabel, Evangeline Keisha; Lu, Felisha; Lestari, Fajar Sri; Branitasandini, Regina Epiphania
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 21, No 1 (2024)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.007311

Abstract

Burn injuries are a significant global health concern due to their profound impact on morbidity and mortality rates. Immediate medical care is essential given the potential for bacterial infections to complicated burn injuries. Binahong leaves (Anredera cordifolia (Ten.) Steenis) contain vitexin compounds that demonstrate wound healing and antibacterial potential. However, vitexin has low solubility, prompting the use of ethanol for extraction and the introduction of nanoparticle technology to enhance solubility, namely transfersomes. The present study explored the development of a gel using binahong extract transfersomes with the composition of carbopol 940 and Na-CMC to determine the effect of carbopol 940, Na-CMC, and the interaction of the two on the gel’s physical properties and stability as well as obtain the optimum composition of the two. This study demonstrates positive results in terms of gel physical properties, including pH, spreadability, and viscosity. A Factorial design method is used for optimization. The results showed that Na-CMC had the most effect on increasing viscosity, while carbopol 940 had the most effect on reducing spreadability. The optimal formula obtained in this research was to use 0.653 grams of Na-CMC and 4.391 grams of Carbopol as gelling agents. 
Spray Gel Formulation of Goroho Banana (Musa acuminata L.) Peel Extract: Optimization and Wound Healing Activity Analysis Salainti, Madeleine Trisha; Yuliani, Sri Hartati
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 22, No 2 (2025)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.0011512

Abstract

Goroho banana (Musa acuminata L.) peel extract has been traditionally used in Minahasa for wound healing. This study aimed to develop and optimize a spray gel formulation containing Goroho banana peel extract and evaluate its wound healing activity. A factorial design was employed with two factors (Carbopol 940 and HPMC) at two levels. Preliminary testing determined 3% as the optimal extract concentration through wound healing evaluation in rats. Four spray gel formulations were developed and characterized for physicochemical properties, including viscosity, pH, and drying time. Results showed Formula B (Carbopol 0.5% and HPMC 0.6%) exhibited optimal characteristics with viscosity 223.8 ± 7.6 cPs, pH 5.13 ± 0.05, and drying time 4.22 ± 0.05 minutes. The HET-CAM irritation test revealed mild irritation scores (2.5-3.8) for all formulations, with Formula B showing the lowest score (2.5). Design Expert optimization generated 100 solutions, with the optimal formula containing Carbopol 0.670% and HPMC 0.517%. The wound healing activity showed no significant differences between spray gel formulations and Bioplacenton (p0.05), indicating comparable efficacy. This study demonstrates the successful development of a safe and effective spray gel formulation of Goroho banana peel extract for wound healing applications.
Pengendalian Vektor DBD Berbasis Komunitas melalui Pelatihan Pembuatan Ovitrap di Desa Piyaman Wandansari, Eustachia Diajeng; Waskitha, Stephanus Satria Wira; Wibowo, Safri Sekti; Hede, Marry Grace Florensia; Tulung, Cindy Stevani; Kinanthi, Eleonora Galuh Windu; Sihombing, Meisyah Marito; Yuliani, Sri Hartati
Jurnal Medika: Medika Vol. 4 No. 4 (2025)
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/ds43bj92

Abstract

Demam Berdarah Dengue (DBD) masih menjadi masalah kesehatan utama masyarakat di Kabupaten Gunung Kidul. Desa Piyaman diidentifikasi sebagai wilayah endemis yang menuntut strategi penanggulangan vektor berkelanjutan. Kurangnya pemahaman masyarakat terkait teknologi pengendalian vektor yang efektif, seperti metode surveilans populasi nyamuk, menjadi penghalang utama upaya pencegahan. Program pengabdian masyarakat (PkM) ini bertujuan meningkatkan kompetensi kader kesehatan serta warga dalam pembuatan dan implementasi ovitrap, sebagai instrumen pengendalian vektor Aedes aegypti berbasis komunitas. Kegiatan dilaksanakan di Balai Padukuhan Desa Piyaman pada 27 Mei 2025 dengan melibatkan 18 peserta, melalui pendekatan partisipatif. Metode pelaksanaan meliputi tiga tahapan utama: penyuluhan, demonstrasi teknis, dan praktik langsung. Evaluasi menggunakan pre-test untuk mengukur pemahaman awal dan umpan balik kualitatif untuk menilai perubahan pemahaman peserta. Hasil pre-test menunjukkan adanya kesenjangan pengetahuan mengenai ovitrap (2,28 ± 1,31 dari 7; 32,57%), meskipun pengetahuan peserta mengenai aspek umum (3,11 ± 0,65 dari 4; 77,75%) dan pencegahan DBD (3,03 ± 0,73 dari 4; 75,75%) sudah relatif baik. Umpan balik kualitatif mengindikasikan keberhasilan peningkatan penguasaan teknis, munculnya komitmen implementasi mandiri, serta intensi diseminasi pengetahuan. Seluruh peserta berhasil membuat ovitrap menggunakan bahan lokal dan berkomitmen menerapkannya di lingkungan masing-masing. Program ini mendemonstrasikan efektivitas pemberdayaan komunitas dalam mengatasi kesenjangan pengetahuan, menjadikannya model intervensi berkelanjutan untuk penanggulangan vektor DBD di wilayah endemis.
Co-Authors Achmad Fudholi Adi, Antonius Iswara Agnes Mutiara Kurniawan Agustina Setiawati Ani, Ni Wayan Annabel, Evangeline Keisha Arini Safti Sandrapitaloka Arpan, Verdynant Augusto Ayaga Divadi Bernadetta Karina Sekar Maheswari Bertha Nathania Branitasandini, Adhika Branitasandini, Regina Epiphania Branitasandini, Regina Epiphania Adhika Christofori Maria Ratna Rini Nastiti Chusien, Adhita Wicaksaneng Naya Brena David Chandra Putra Desi Amroni Kasanah Dina Christin Ayuning Putri Dita Maria Virginia Elaina Elaina Elliora, Greata Elsa Irnandari Enade Perdana Istyastono Enade Perdana Istyastono Enade Perdana Istyastono Enade Perdana Istyastono Enade Perdana Istyastono Evy Fenny Veronica Felicia Satya Christania Florentinus Dika Octa Riswanto Fransiska Revana Restiana Gani, Michael Raharja Handika Immanuel Hede, Marry Grace Florensia Ignasius Adi Kurniawan Kerenhapukh, Miracle Kinanthi, Eleonora Galuh Windu Lestari, Fajar Sri Lewier, Bryan Melianus Agustinus Limianty, Angela Lu, Felisha Marchaban . Maria Faustina Sari Maria Ludya Pulung Maywan Hariono Melviya Sudianto Melynia Sintha Dewi Michael Raharja Gani Michael Raharja Gani Michael Raharja Gani Michael Raharja Gani Novela, Yuven Nugraha, Alvin Arya Nunung Yuniarti Paulus Unggul Wikan Prabandono Pebrianty, Sahara Petrus Damiani Tosan Aji Prita Patricia Radite Yogaswara reza eka putra Rini Dwiastuti Rini Dwiastuti Salainti, Madeleine Trisha Sara Septi Widayani Shirley Candra Kurniawan Sihombing, Meisyah Marito Sudianto, Melviya Suwijiyo Pramono Tasik, Sulistiana Tulung, Cindy Stevani Wandansari, Eustachia Diajeng Wardhani, Kresentia Ayu Kusuma Waskitha, Stephanus Satria Wira Wibowo, Safri Sekti Yulia Yulia YUMI RAHMADANI