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All Journal Jurnal Pengabdian Masyarakat (ABDIRA) Proceeding of Mulawarman Pharmaceuticals Conferences Journal of Tropical Pharmacy and Chemistry
Lisna Meylina
Laboratorium Penelitian dan Pengembangan Kefarmasian "Farmaka Tropis", Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia
Aerospace Engineering Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Social Sciences Other

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Formulation and Evaluation of N-Hexane Fraction of Libo Fruit based Emulgel for Sunscreen Yuni Dwi Anjarwati; Lisna Meylina; Rolan Rusli
Journal of Tropical Pharmacy and Chemistry Vol. 7 No. 2 (2023): J. Trop. Pharm. Chem.
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jtpc.v7i2.527

Abstract

Libo fruit (Ficus variegata Blume) has activity as a sunscreen. Topical form of certain pharmaceuticals can be used to protect the skin from sun exposure. This study aims to determine the best gel-emulsion formula from the libo’s N-Hexane fraction, its stability, and its sunscreen activity. The formula was consist gelling agents variations type and concentration, i.e.  carbopol 940 and hydroxypropyl methylcellulose (HPMC). The best formula were chosen based on physicochemical characteristics. the freeze-thaw test deployed to check the stability, and the sunscreen activity was tested using UV-Vis spectrophotometry. The results showed that the best formula was formula 1 with carbopol 940 (1%), there were no changes in physicochemical characteristics during the stability test, and experienced a decrease in sunscreen activity after the stability test.
Pembuatan Simplisia Rimpang-rimpangan dan Dorongan Pembentukan Ukot Umot pada Kelompok Tani Desa Lempake Samarinda Sulistiarini, Riski; Nisaa, Nur Rezky Khairun; Farah, Harra Ismi; Arifian, Hanggara; Meylina, Lisna; Rijai, Akhmad Jaizzur; Prasesti, Gayuk Kalih
Jurnal Pengabdian Masyarakat (ABDIRA) Vol 5, No 1 (2025): Abdira, Januari
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/abdira.v5i1.568

Abstract

The community service activity themed "Preparation of Rhizome Simplisia and Encouragement for the Formation of Ukot Umot in the Farmer Group of Lempake Village, Samarinda" aimed to increase public knowledge about the preparation of high-quality rhizome simplisia and to encourage the establishment of local institution-based organizations (Ukot Umot). The activity involved farmer groups, women's PKK groups, and village officials. The materials presented included stages of washing, cutting, drying, and storing simplisia. Additionally, a participatory discussion on the importance of Ukot Umot institutions was conducted to strengthen collaboration and improve market access. Based on an evaluation through a questionnaire, 100% of participants stated that the activity was highly beneficial, with high satisfaction levels regarding the relevance of the material, the delivery method, and the benefits of the activity. The initial impacts of the activity included increased participant knowledge, a commitment to forming Ukot Umot, and motivation to process rhizomes independently. Despite challenges such as limited facilities, this activity successfully laid the foundation for the sustainable development of rhizome-based businesses.
Synthesis and Toxicity Tests of N-Carbothioamide-3-(2,4- Dichlorophenyl)-5-(4-Hydroxy-3-Methoxyphenyl)Pyrazoline Irfan, Muhammad; Meylina, Lisna; Ramadhani, Agung; Rusli, Rolan
Journal of Tropical Pharmacy and Chemistry Vol. 8 No. 1 (2024): J. Trop. Pharm. Chem.
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jtpc.v8i1.612

Abstract

Pyrazoline is an alkaloid compound which has various biological activities such as antibacterial, antifungal, antitumor and anticancer. The compound N-carbotioamide-3-(2,4-dichlorophenyl)-5-(4-hydroxy-3-methoxyphenyl)pyrazoline was successfully synthesized from the basic ingredients 2',4'-dichloro-4-hydroxy-3-methoxychalcone and thiosemicarbazide with sodium hydroxide catalyst at 80°C for 7 hours. The synthesized compound was characterized using 1H-NMR, 13C-NMR, and mass spectroscopy and had a yield of 28.03%. Based on the results of toxicity tests using the Brine Shrimp Lethality Test (BSLT) method, this compound has an LC50 value of 44.6 ppm and has the potential to be an antimicrobial compound.
Co-Authors Adam M. Ramadhan Angga Cipta Narsa Arifian, Hanggara Arsyik Ibrahim Ayu Kusumah Dewi Farah, Harra Ismi Fitriani Fitriani Hajrah Hajrah Jaka Fadraersada Laode Rijai Miftachul Ainin Chambali Muhammad Irfan Nisaa, Nur Rezky Khairun Nova Mega Handayani Nurul Hasanah Prasesti, Gayuk Kalih Raehan Natul Jannah Ramadhani, Agung Restu Harisma Damayanti Rijai, Akhmad Jaizzur Risa Yusnita Rolan Rusli Sulistiarini, Riski VICTORIA YULITA FITRIANI Yoni Miftahun Nafsiyah Agustin Yunaedi Yunaedi Yuni Dwi Anjarwati Yurika Sastyarina