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Journal : JURNAL FARMASIMED (JFM)

ETHANOL EXTRACT LIQUID SOAP FORMULATION LEAVES OF CELERY (Apium graveolens L.) AGAINST Escherichia coli BACTERIA Irwanto, Reno; Apriani Girsang, Santa Dewi; Maria Ginting, Wira; Novia, Reni
Jurnal FARMASIMED (JFM) Vol 5 No 2 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i2.1584

Abstract

Dirty hands will be a source of disease. Soap is a pharmaceutical preparation used to maintain health. Celery (Apium graveolens L.) is a plant of the Apiaceae tribe with a distinctive menthol aroma. This study aimed to determine the inhibitory power of celery leaf extract formulation (Apium graveolens L.) as an antibacterial hand-washing soap. This research method is a type of experimental research. The stages of the research were collecting samples, identifying plants, making simplicia, characterizing simplicia, screening phytochemicals, making extracts and making hand soap formulations of celery leaf extract (Apium graveolens L) at concentrations of 5%, 10%, 15% and antibacterial testing of celery leaves, against Escherichia coli bacteria. The results showed the celery leaf extract soap formulation contained phytochemical compounds of flavonoids, tannins and saponins. The organoleptic test found that the best soap formulation was the F2 formulation with a concentration of 10% at an average level of preference value, namely 3.67 for colour, 3.27 for aroma, and 3.80 for texture. The homogeneity test performed showed that all formulations produced soap with good homogeneity. The height and stability test of the resulting celery extract soap foam ranged from 61-71 mm. The irritation test of the resulting celery extract soap also showed no irritation for all the formulations. The value of the antibacterial activity test found that the F1 formulation showed antibacterial activity with an inhibition zone diameter of 3 (weak), F2 with an inhibition zone of 9 (moderate) and F3 with the antibacterial activity of 12 (strong).
ORGANOLEPTIC TESTS AND ANTIOXIDANT ACTIVITY OF BLACK SOYBEAN (GLYCINE SOJA L) SUPPLEMENTED TAMARILLO(SOLANUM BETACEUM CAV) Irwanto, Reno; Novia, Reni; Rantika, Windy
Jurnal FARMASIMED (JFM) Vol 6 No 1 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v6i1.1952

Abstract

Degenerative disease refers to metabolic syndrome which occurs as a result of an unhealthy lifestyle. An unhealthy diet results in the emergence of large amounts of free radicals. High free radical content can disrupt cells and their genetic material which can result in degenerative diseases. Antioxidants are compounds that function to protect body cells from damage caused by free radicals that cause degenerative diseases. Soybean juice added with tamarillo is a food ingredient that is a source of antioxidants. The aim of the research was to obtain the best Dutch eggplant formula added to soy milk. The research method used was a Completely Randomized Design (CRD) which involved four additional treatments of Dutch eggplant, namely P1 (50 mL), P2 (55 mL), P3 (60 mL) and P4 (65 mL). Research activities were initially carried out by testing the organoleptic products using the hedonic method by 70 untrained panelists. Product testing is carried out using Then the best product testing results are continued to be tested for antioxidant content. Antioxidant testing The results of the organoleptic test research obtained the highest scores for the color attribute 5.69 (P3), aroma 5.23 (P2), taste 6.09 (P1), texture 4.76 (P1), and overall 5.81 (P1). Based on organoleptic tests, the best formula is 60 mL (P3) then the antioxidant activity test is 0.3374 ppm. The conclusion in this study shows that the best formula in terms of color, taste and overall black soybean juice added with Dutch eggplant has significant antioxidants.