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OPTIMASI FASE GERAK KROMATOGRAFI CAIR KINERJA TINGGI PADA PENETAPAN KADAR PIPERIN BUAH CABE JAWA (Piper Retroofactum Vahl.) Christina, Odilia Dea; Nurul, Aisiyah; Ina, Ayu
Jurnal Farmasi & Sains Indonesia Vol 7 No 1 (2024)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol7no1p187-191

Abstract

Piperine is the main alkaloid compound found in various types of pepper, including long pepper (Piper retrofractum Vahl.). Determining the piperine content in natural materials and processed products is important in the context of quality control and pharmaceutical research. The analytical method frequently used for determining piperine content is High-Performance Liquid Chromatography (HPLC). One critical factor in HPLC analysis is the selection and optimization of the mobile phase. This study aims to optimize the mobile phase in HPLC analysis to determine piperine content. The mobile phases used were acetonitrile:methanol:distilled water (60:10:30) and acetonitrile:methanol:distilled water (65:5:30). The results showed that the optimal mobile phase for determining piperine content using HPLC is a mixture of acetonitrile:methanol:distilled water in the ratio of 65:5:30 (v/v)
Uji Efektivitas Penyembuhan Luka Bakar dari Sediaan Gel Ekstrak Daun Jarak Pagar (Jatropha Curcas L) pada Tikus Putih Jantan (Rattus Norvegicus) Mesak, Ivan; Christina, Odilia Dea; T.I., Angelina
Jurnal Farmasi & Sains Indonesia Vol 7 No 1 (2024)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol7no1p172-178

Abstract

The occurrence of burns on the skin is a type of injury that requires fast and appropriate treatment in order to achieve an optimal level of healing. Handling burns using medicinal plants can be done. One of the plants that can be used is Jatropha leaves. Jatropha leaves contain active substances such as saponins, tannins, alkaloids, and flavonoids that are efficacious as antibacterial, antioxidant, anticancer and antiinflammatory. The purpose of this study was to determine the effectiveness of Jatropha curcas leaf extract gel preparations with concentrations of 10%, 15%, 20% on burn wound healing. This study is an experimental study by comparing the effectiveness of burn wound healing in rats in each test group, namely negative control given gel base, positive control given Bioplacenton gel, and three test control groups with each given Jatropha leaf extract gel concentrations of 10%, 15% and 20%. The test results show that the most effective Jatropha leaf extract gel preparation heals rat burns, namely the 20% concentration compared to the positive control with a P>0.914 value (P>0.05).
FORMULASI DAN EVALUASI SEDIAAN SAMPO KOMBINASI EKSTRAK BONGGOL PISANG KEPOK (Musa x paradisiaca L.) dan MINYAK KELAPA (Virgin Coconut Oil) Akbar, Nanda Dwi; Cahyaningrum, Nineeteen Yuliya; Setiyaningsih, Wahyu; Solichah, Ayu Ina; Christina, Odilia Dea
Jurnal Farmasi & Sains Indonesia Vol 8 No 1 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no1p176-187

Abstract

Shampoo is a hair care product that is used to clean the hair and scalp.Shampoo containing natural ingredients can be an alternative for healthy scalp and hair.The saponin content in the kepok banana hump (Musa x paradisiaca L.) can function as a foamer and a combination of coconut oil (Virgin coconut oil) as a moisturizer (emollient).This research aims to formulate and evaluate a shampoo preparation containing banana weevil extract (Musa x paradisiaca L.) and coconut oil (Virgin coconut oil) in the shampoo preparation. This research is an experimental research. In this research, the formulation of kepok banana weevil extract (Musa x paradisiaca L.) 4%, 8% and 12% and coconut oil (Virgin coconut oil) concentrations of 10%, 12% and 15% were carried out. Extract yield was carried out using the maceration method using 96% ethanol solvent with a ratio of 1: 7.5. Evaluation of the physical properties of shampoo includes organoleptic observations, pH determination, specific gravity measurement, foam height measurement, viscosity and homogeneity testing.Data analysis was carried out using SPSS. Based on research on kepok banana weevil extract (Musa x paradisiaca L.)a thick, reddish brown colored extract was obtained, with a distinctive slightly sweet aroma with a yield of 11.4445% from 400 grams of dried banana weevil. The results of the phytochemical screening of the thick extract of banana weevils were positive for containing saponin compounds. The test results for shampoo preparations F1, F2 and F3 have a cream to brownish cream color, a liquid texture and a coconut banana smell, homogeneous preparations, pH range 6.72 – 8.23; has a foam height of 1.8 – 2.3 cm; viscosity 216 – 250 dPas and specific gravity 0.9569 – 1.0272 g/mL. The results of analysis using One Way ANOVA showed a p value <0.05 in foam height, pH value and viscosity for the three formulas, there were significant differences.This research shows that the addition of banana weevil extract (Musa x paradisiaca L.) and coconut oil (Virgin coconut oil) affects the characteristics of the shampoo preparation.
INTENSIFIKASI LAHAN PEKARANGAN MENJADI HERBAL SMART GARDEN DI KELURAHAN KALISEGORO GUNUNGPATI SEMARANG Suwarni, Sri; Christina, Odilia Dea; Sitepu, Harum; Trimonica, Tessa
BESIRU : Jurnal Pengabdian Masyarakat Vol. 1 No. 9 (2024): BESIRU : Jurnal Pengabdian Masyarakat, September 2024
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/p8ds0k76

Abstract

Intensifikasi lahan di kelurahan dan pekarangan warga menjadi Solusi untuk lahan pekarangan yang tidak digunakan menjadi bermanfaat dan menambahkan nilai keuntungan yaitu memudahkan kebutuhan obat penyakit ringan di masyarakat . Lahan Pekarangan di Kelurahan Kalisegoro Gunungpati Semarang diberdayakan menjadi Herbal Smart Garden oleh tim urban farming, remaja dan lansi dimulai dengan penyuluhan macam-macam tanaman berkhasiat obat  hingga cara pengolahan urban farming tanaman herbal yang dibibitkan dengan menggunakan media polybag dilatihkan cara pengolahan tanah serta penanamanya akan menjadi berguna untuk msyarakat, dan informasi tentang khasiat dan pemgolahan menjadi obat dengan smart dapat menggunakan sistem informasi ataupun e-katalog tanaman obat yang ditanam di herbal garden tersebut. Tanah yang kosong termanfaatkan menjadi lahan sumber tanaman obat yang dapat digunakan untuk kepentingan penyakit ringan dan imunitas tubuh Masyarakat itu sendiri.