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All Journal Majalah Kedokteran Bandung Althea Medical Journal Jurnal Sistem Kesehatan JURNAL PENDIDIKAN JASMANI DAN OLAHRAGA Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Indonesian Journal of Obstetrics & Gynecology Science JTP - Jurnal Teknologi Pendidikan JK Unila (Jurnal Kedokteran Universitas Lampung)
Yuni Susanti Pratiwi, Yuni Susanti
Department of Physiology Universitas Padjadjaran Bandung
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Journal : Althea Medical Journal

 1 
Characteristics of Hypertension in Children at Dr. Hasan Sadikin General Hospital Bandung in January to December 2014 Meilani, Meilani; Sekarwana, Nanan; Pratiwi, Yuni Susanti
Althea Medical Journal Vol 4, No 3 (2017)
Publisher : Althea Medical Journal

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Abstract

Background: Hypertension is often found in children. It could cause serious complications and added risk of hypertension in adulthood. Hypertension in children is likely secondary type and some of them might be severe. The aim of this study was to determine the demographic and clinical characteristics of hypertension in children admitted to Dr. Hasan Sadikin General Hospital Bandung in January to December 2014.Methods: The study design used was a quantitative, descriptive cross-sectional study. Data were obtained from medical records retrospectively of inpatient children from the period January to December 2014. Data were collected from the period  September to November 2015 based on age and gender as a demographic characteristics and stage of hypertension, etiology of hypertension, and emerge of hypertensioncomplication as a clinical characteristics.Results: Ninety(1.9%)children with hypertension were found from 4,681 of total inpatient children consisting of 58 males and 32 females with median of age 8 (0−13) years old.The main stage of hypertension was hypertension stage 2 with 55 cases and nephrotic syndrome as the most common causes with 43 cases. The complications were present in hypertension stage 2 with 3 cases and hypertensive crisis with 2 cases.Conclusions: Children with hypertension are most commonly males and median of age was 8 years old. Hypertension is characterized by hypertension stage 2 and nephrotic syndrome as the most common etiology. Complications of hypertension appear in severe hypertension.
Profile of Handgrip Strength, Anthropometry, Nutritional Status and Activities of Daily Living Among Geriatrics at Karitas Nursing Home, Bandung Rajendran, Thawaneswaaran; Novitri, Novitri; Pratiwi, Yuni Susanti
Althea Medical Journal Vol 2, No 1 (2015)
Publisher : Althea Medical Journal

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  Background: Reduced handgrip strength is an aging process that influences the activities of daily living among elderly people. Handgrip strength varies greatly with age, gender, anthropometric measurement and nutritional status. This study aimed to determine the profile of handgrip muscle strength, physical characteristic, nutritional assessment and activities of daily living among elderly Methods: This study was conducted at Karitas nursing home, Bandung on September 2012. This is a descriptive study by collecting primary data from 28 elderly people. Data were collected in 2 days within 2 weeks. The first data collection included details of anthropometric measurement and handgrip measurement. The second data collection included face to face interview using standardized questionnaire for mini nutritional assessment and Barthel index.Result: The mean age of the respondents was 74.14 ± 8.5189 years. The average reading on handgrip muscle strength was 30.84 ± 12.0175 lbs for right hand and 27.77 ± 11.3778 lbs for left hand. For anthropometric measurement, most of the respondents had normal weight body mass index status (39.3%). Nutritional status of respondents evaluated by mini nutritional assessment showed that most of the respondents were at risk of malnutrition (64.3%). The activities of daily living assessment based Barthel Index showed that half of the respondents were dependent in activities of daily living (50%).Conclusions: From this  study, it can be concluded that the grip strength of all the respondents are weaker. Majority have normal body weight, malnutrition risk, and half of the subjects are depend on others in doing their daily activities.Keywords: Activities of daily living, anthropometry, elderly, handgrip strength, nutritional status DOI: 10.15850/amj.v2n1.423 
Curcuma longa L. Prevents Hepatotoxicity Induced Isoniazid and Rifampicin: An Experiment in Wistar Rats Model Rahman, Putri Halleyana; Dwiwina, Resti Gradia; Pratiwi, Yuni Susanti; Bashari, Muhammad Hasan
Althea Medical Journal Vol 11, No 2 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v11n2.3161

Abstract

Background: Hepatotoxicity induced by the combination of isoniazid (INH) and rifampicin (RIF) in the treatment of tuberculosis (TB) remains a major concern. Oxidative stress has a role in mechanism of hepatotoxicity. Curcuma longa L. has been widely used as a traditional medicine and has shown antioxidant activity. This study aimed to provide evidence of Curcuma longa L as protection against oxidative stress induced by isoniazid and rifampicin therapy.Methods: This was an experimental study on male Wistar rats weighing 150-200 grams, aged 8-10 weeks which were divided into a negative control group (K0), a positive control group with INH + RIF (K1), a treatment group with a dose of 2.2 gr/kg/day Curcuma longa L powder (K2), and treatment group with INH+RIF and additional 2.2 gr/kg/day turmeric rhizome powder (K2+). SGOT and SGPT were measured from blood plasma on the 28th day; then hepatic tissue was obtained to measure MDA levels and observed histologically. Statistical analysis was done using ANOVA and continued with Duncan procedure using SPSS ver. 27.Results: SGOT, SGPT, the highest average MDA level in the liver, and the highest mean necrotic cell count in the positive control group showed a significant difference (p<0.05). The treatment group had a smaller average number of necrotic cells than the positive control group with a significant difference (p <0.05).Conclusion: Curcuma longa L powder has been shown to prevent elevation in SGOT, SGPT, MDA of liver tissue and hepatocyte necrosis, indicating its potential in protecting the liver from oxidative stress.
Co-Authors Achadiyani Aldo, Mochammad Ambrosius Purba Andi Rinaldi Aprianti, Nurul Azmi Bashari, Muhammad Hasan Dany Hilmanto Goenadi, Julia Windi Hanna Goenawan Hanom Husni Syam Hartanto Bayuaji Irvan Afriandi Iwan Setiawan Johanes C. Mose Kemala Isnainiasih Mantilidewi Laranova, Atri Maharani, Chintia Dewi Meilani Meilani, Meilani Nanan Sekarwana Nova Sylviana Novitri, Novitri Prasetyo, Wibowo Budi Rahman, Putri Halleyana Ray, Hamidie Ronald Daniel Resti Gradia Dwiwina Ritonga, Mulyanusa Amarullah Ronny Lesmana Setiawan Setiawan Setyorini Irianti Susi Susanah Susiarno, Hadi Thawaneswaaran Rajendran, Thawaneswaaran Unang Supratman Vita Murniati Tarawan