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All Journal Dimas: Jurnal Pemikiran Agama untuk Pemberdayaan Global Medical and Health Communication MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan Jurnal Integrasi Kesehatan dan Sains Jurnal Riset Kedokteran Bandung Conference Series : Medical Science
Maya Tejasari
Bagian Biologi Medik Dan Histologi, Fakultas Kedokteran, Universitas Islam Bandung, Bandung
Humanities Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Gambaran Karakteristik Kanker Payudara Eneng Mira; Maya Tejasari; Listya Hanum Siswanti
Bandung Conference Series: Medical Science Vol. 4 No. 1 (2024): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v4i1.10639

Abstract

Abstract. The most common malignant disease in women is breast cancer. In the world the number of breast cancer sufferers has reached 2.3 million. The occurrence of breast cancer can be caused by several risks, including age, parity status, history of breastfeeding and use of hormonal contraception. This study aims to determine the characteristics of breast cancer patients. This research used a retrospective descriptive method which took place at Al-Ihsan Regional Hospital with 182 research subjects. Data was obtained from secondary data from medical records in the form of age characteristics, breastfeeding history, parity status and use of hormonal contraceptives. The results of the research show that the majority of breast cancer patients at Al-Ihsan Regional Hospital in 2022 are in the 46-55 year age group, namely 70 people (38.4%), 161 people have a history of breastfeeding (88.4%), parity status is mostly 2 –3 children totaling 132 people (72.5%) and using hormonal contraception as many as 155 people (85.2%). This is related to the high levels of the hormones estrogen and progesterone which influence the risk of breast cancer, thus inhibiting the tumor suppressor genes BRCA1 and BRCA2 which causes breast gland cell proliferation to increase. ​Abstrak. Penyakit keganasan terbanyak pada wanita adalah kanker payudara. Di dunia jumlah penderita kanker payudara mencapai angka 2,3 juta. Terjadinya kanker payudara dapat disebakan oleh beberapa risiko, diantaranya adalah usia, status paritas, riwayat menyusui dan penggunaan kontrasepsi hormonal. Penelitian ini bertujuan untuk mengetahui karakteristik pasien kanker payudara. Penelitian ini menggunakan metode deskriptif retrospektif yang bertempat di RSUD Al-Ihsan dengan Subjek penelitian sebanyak 182 orang. Data diperoleh dari data sekunder rekam medis berupa karakteristik usia, riwayat menyusui, status paritas dan penggunaan kontrsepsi hormonal. Hasil penelitian menunjukan mayoritas pasien kanker payudara di RSUD Al-Ihsan tahun 2022 pada kelompok usia 46-55 tahun yaitu sebanyak 70 orang (38,4%), riwayat menyusui sebanyak 161 orang (88,4%), status paritas sebagian besar mempunyai 2–3 anak sebanyak 132 orang (72,5%) dan memakai kontrasepsi hormonal sebanyak 155 orang (85,2%). Hal tersebut berkaitan dengan tingginya hormon estrogen dan progesteron yang berpengaruh terhadap risiko terjadinya kanker payudara, sehingga meng-inhibisi tumor supresor gen BRCA1 dan BRCA2 yang menyebakan proliferasi sel kelenjar payudara meningkat.
Gambaran Kombinasi Rejimen Kemoterapi pada Penderita Kanker Payudara Luminal B di RSUD Al-Ihsan Bandung Evana Sandhiya Riksabaya; Maya Tejasari; Listya Hanum Siswanti
Bandung Conference Series: Medical Science Vol. 4 No. 1 (2024): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v4i1.10907

Abstract

Abstract. Luminal B breast cancer is a tumor that has high levels of estrogen receptor positive, progesterone receptor negative, and HER2 positive. HER2 positivity makes breast cancer have a higher genomic risk than luminal A, so the prognosis for luminal B is worse than luminal A. Luminal B breast cancer tends to benefit from chemotherapy. This study aims to understand the description of combination chemotherapy regimens in luminal B breast cancer sufferers at Al-ihsan Hospital Bandung in 2018 - 2022. The number of samples was 222 taken from Al-Ihsan Hospital Bandung. Data was obtained from medical records in the form of breast cancer diagnosis, age, gender, and regimen combination. This technique uses total sampling. Using quantitative observational methods with a cross sectional research design and data analysis using Chi-Square. The research results show that in 2018-2019 the most widely used regimen was DOCE + CYCLOF with percentages of 80% and 48%. In 2020-2021, the majority will be FAC with percentages of 59.2% and 35.1%. In 2022, the majority will be DOCE + CARB (43.9%). The conclusion of this study is to show an overview of the chemotherapy regimen combination for luminal B breast cancer that was most widely used in 2018-2019, namely DOCE + CYCLOF, in 2020-2021, namely FAC, and in 2022, namely DOCE + CARB. Abstrak. Kanker payudara luminal B merupakan tumor yang memiliki reseptor estrogen positif tingkat tinggi, reseptor progesteron negatif, dan HER2 positif. HER2 positif membuat kanker payudara memiliki risiko genomik yang tinggi dibanding luminal A, sehingga prognosis luminal B lebih buruk dibanding luminal A. Kanker payudara Luminal B cenderung mendapat manfaat dari kemoterapi. Penelitian ini bertujuan untuk memahami gambaran kombinasi rejimen kemoterapi pada penderita kanker payudara luminal B di RSUD Al-ihsan Bandung tahun 2018 - 2022. Jumlah sampel yaitu 222 yang diambil dari RSUD Al-Ihsan Bandung. Data diperoleh dari rekam medis berupa diagnosis kanker payudara, usia, jenis kelamin, dan kombinasi regimen. Teknik ini menggunakan total sampling. Menggunakan metode kuantitatif observasional dengan desain penelitian cross sectional dan analisis data menggunakan Chi-Square. Hasil penelitian menunjukan pada tahun 2018-2019 regimen yang paling banyak dipakai yaitu DOCE + CYCLOF dengan persentase sebesar 80% dan 48%. Pada tahun 2020-2021 sebagian besar yaitu FAC dengan persetase sebesar 59.2% dan 35.1%. Pada tahun 2022, sebagian besar yaitu DOCE + CARB (43.9%). Kesimpulan penelitian ini adalah menunjukan gambaran kombinasi regimen kemoterapi pada kanker payudara luminal B yang paling banyak digunakan pada tahun 2018-2019 yaitu DOCE + CYCLOF, pada tahun 2020-2021 yaitu FAC, dan pada tahun 2022 yaitu DOCE + CARB.
Karakteristik Manifestasi Klinis Pasien dengan Dermatitis Kontak di RSUD Cibabat Karina Dinda Azzahra; Maya Tejasari; Deis Hikmawati
Bandung Conference Series: Medical Science Vol. 4 No. 1 (2024): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v4i1.11077

Abstract

Abstract. Abstract. Contact Dermatitis is an inflammatory skin disease caused by contact exposure to allergens and irritants. Irritant Contact Dermatitis (DKI) is a complex reaction caused by intrinsic (genetic) and extrinsic (environmental) factors. Allergic Contact Dermatitis (DKA) is an immune reaction of the skin to one or more allergens that come into contact with the skin. In 2017, it is estimated that there were around 1090 people with cases of occupational skin disease, of which 79% were contact dermatitis. The aim of this study was to determine the characteristics of clinical manifestations of patients with contact dermatitis. The design of this research was an analytical observational study with a cross-sectional design conducted at the Cibabat District Hospital with a total of 137 patients. Data was obtained from medical records in the form of type of exposure and clinical manifestations and a diagnosis of DKA or DKI. The results of the study showed that the most common clinical manifestations were itching (80.29%) and redness (62.77%) compared to stinging (37.23%), burning (26.28%) and dry skin ( 24.82%). The conclusion of this study is that the majority of patients experience itching and redness as clinical manifestations of contact dermatitis. This is caused by the effects of the release of cytokines and irritation of the skin which causes inflammation and manifests in patient complaints. Abstrak. Dermatitis Kontak merupakan penyakit inflamasi kulit yang disebabkan oleh paparan kontak alergen dan iritan. Dermatitis Kontak Iritan (DKI) merupakan reaksi kompleks yang disebabkan oleh faktor intrinsik (genetik) dan extrinsik (lingkungan). Dermatitis Kontak Alergi (DKA) merupakan reaksi kekebalan kulit terhadap satu atau lebih alergen yang bersentuhan dengan kulit. Pada tahun 2017 diperkirakan terdapat sekitar 1090 orang dengan kasus penyakit kulit akibat kerja dimana 79% nya merupakan dermatitis kontak. Tujuan dari penelitian ini adalah untuk mengetahui karakteristik manifestasi klinis pasien dengan dermatitis kontak. Desain penelitian ini adalah penelitian analitic observational dengan rancangan cross-sectional yang dilakukan di RSUD Cibabat dengan total subyek yang didapatkan adalah 137 pasien. Data diperoleh dari rekam medis berupa jenis paparan dan manifestasi klinis dan didiagnosis DKA atau DKI. Hasil penelitian menunjukan bahwa manifestasi klinis yang paling banyak terjadi adalah rasa gatal (80,29%) dan kemerahan (62,77%) dibandingkan dengan rasa perih (37,23%), rasa terbakar (26,28%) dan kulit kering (24.82%). Simpulan penelitian ini adalah sebagian besar pasien mengalami rasa gatal serta kemerahan sebagai manifestasi klinis dari penyakit dermatitis kontak. Hal ini disebabkan oleh efek dari dilepaskannya sitokin serta irirtasi pada kulit yang menyebabkan inflamasi dan bermanifestasi terhadap keluhan pasien.
“Output Research Supporting Class” Manuscript Writing Training to Avoid Misconduct in an Islamic Perspective Yuniarti, Lelly; Batara, Triando; Garna, Herry; Tejasari, Maya
Dimas: Jurnal Pemikiran Agama untuk Pemberdayaan Vol. 23 No. 2 (2023)
Publisher : LP2M of Institute for Research and Community Services - UIN Walisongo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21580/dms.2023.232.13495

Abstract

The tridharma point that is most challenging for a lecturer to achieve is research, and currently, the benchmark for the research field is scientific publications. However, in reality, there are still many lecturers who are hampered in fulfilling research outputs in the form of scientific publications, this is because lecturers experience difficulties in compiling manuscripts of research results for publication. There are currently 144 lecturers at the Tasikmalaya Health Engineering Polytechnic and around 50% of the lecturers still have the functional position of expert assistant and do not have a functional position or teaching staff. This PKM aims to improve the ability of Tasikmalaya Health Polytechnic lecturers to compile manuscripts, avoid misconduct, and publish the manuscript in the intended journal. PKM methodThis is done using an Asset Based Community-Driven Development (ABCD) approach, namely focusing on the assets, potential and strengths of the Health Polytechnic lecturers. Workshop and coaching clinic preparing manuscripts, using reference management, and submitting manuscripts to journals. The research results showed that of the 50 participants who took part in the workshop, 15 lecturers succeeded in compiling manuscripts of research results, avoiding misconduct, and improving the manuscripts according to reviewer input. This shows the need for ongoing training and stimulation activities for lecturers in compiling research output.
Co-Authors Aghata Shaumafitri Azzahra Agista Rohani Agly Adithya Agly Adithya, Agly Ahmad, Sadiah Anissa Febie Melati Annisa Rahmah Furqaani Arief Budi Yulianti Azmi Azkiatul Fikri Batara, Triando Bhatara, Tryando Dadang Rukanta Deis Hikmawati Dilla Latul Anjaniah Djanuarsih Iwan Djanuarsih Iwan, Djanuarsih Dwi Prasetyo Dwi Widi Mandasari Eka Nurhayati Eneng Mira Enggar Hestu Enggar Hestu, Enggar Evana Sandhiya Riksabaya Faisal, Sandy Fenda Khafidhotenty Firman Cahayadipura Hasani Farhan Herri S. Sastramihardja Herry Garna Hoirunisa Fathia Hoirunisa Fatiha, Hoirunisa Ismet Muchtar Nur Karina Dinda Azzahra Kharisma, Yuktian Lelly Yuniarti Listya Hanum Siswanti M. Nurhalim Shahib Meta Maulida Damayanti Miranti Kania Dewi Nabila Tarlita Luthfiyah Namira Putri Hermawan Naufal Fadhillah Alam Neng Salma Arina Azmi Noormartany Noormartany Nur Azmiati Mundiri Nurhalim Shahib Raden Anita Indriyanti Retno Ekowati Sadeli Masria Santun Bhekti Rahimah Sara Shafira Shinta Mourinda Rachmani Siti Aminah Abdurachman Siti Annisa Devi Trusda, Siti Annisa Devi Sitti Indah Sari Pratiwi Maradjabessy Titik Respati Umar Islami Usep Abdullah Husin Waya Nurruhyuliawati Wida Purbaningsih Widayanti Widayanti Winni Maharani Winni Maharani Mauliani Yani Triyani Yuktiana Kharisma Zahra Al Khansa Zahrah Qanitah