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All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Majalah Kedokteran Bandung Jurnal Kesehatan Andalas Majalah Kedokteran Andalas Bioscientia Medicina : Journal of Biomedicine and Translational Research Human Care Journal Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Ilmu Kesehatan Indonesia (JIKSI) Jurnal Riset Ilmiah Ophthalmologica Indonesiana
Kemala Sayuti
Universitas Andalas
Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Differential Diagnosis of Leukocoria : A Case Report: Poster Presentation - Case Report - Resident Rahman, Harrie Kurnia; Sayuti, Kemala
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/tap89h21

Abstract

Introduction : Leukocoria is an abnormal pupillary reflex more clearly seen after mydriasis or photography. It is often the first sign of a range of serious intraocular disorders, including congenital cataracts, Coats disease, retinoblastoma, Familial Exudative Vitreoretinopathy (FEVR). Case Illustration : Baby F, 10 months with chief complaint the vision in both eyes appears defocused since birth. A history of trauma to the head is denied, severe pain (-), a history of similar complaints in the family is denied. Pregnancy history: Mother had hypertension. The patient born spontaneusly at 39-40 weeks of gestation, crying immediately, birth weight 2700 grams. Ophtalmology Status ODS: VA Blink reflex(+), Following light (+), Following object (-), Konjungtiva : hiperemis (-), cornea : clear (+), Pupil : leukocoria (+). Funduscopy examination ODS: Vitreus : cloudy (+), papillae: cannot be assessed, blood vessels: visible images of raised blood vessels, retina: detached (+) retinal layers seen, macula: cannot be assessed. USG ODS: cloudy vitreus with hyperreflectivity moderate to high. Patient was diagnosed with Leucocoria ec Retinal Detachment ec Suspect FEVR differential diagnosis Retinoblastoma Bilateral. CT Scan : A mass with a calcified component in the right and left posterior bulbs, consistent with bilateral retinoblastoma Discussion : The clinical history of leukocoria, meaning loss of the normal red retinal reflex, is nonspecific. Key findings here are the normal size of the globes and the presence of calcifications, which are more compatible with retinoblastoma, Coats' disease, or FEVR. Conclusion Leucocoria in aterm baby has several differential diagnosis such as retinoblastoma that needs further examination.
Changes in Retinal Ganglion Cell (RGC) and Retinal Nerve Fiber Layer (RNFL) Thickness in Children with Type 1 Diabetes Mellitus at Dr. M. Djamil General Hospital, Padang, Indonesia lonanda, Gama Agusto; Kemala Sayuti; Havriza Vitresia; Hendriati; Andrini Ariesti; Weni Helvinda
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 8 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i8.1047

Abstract

Background: Type 1 diabetes mellitus (DM) is a chronic metabolic disorder that causes hyperglycemia and increases the risk of morbidity and mortality. Diabetic retinopathy, a microvascular complication that often occurs in DM patients, can cause visual impairment and even blindness. Regular eye examinations are important for early detection of diabetic retinopathy. Optical coherence tomography (OCT) is a non-invasive method that can be used to measure the thickness of retinal layers, including RGC and RNFL. It is thought that thinning of the retinal layer can be a sensitive biomarker in detecting diabetic retinopathy in type 1 DM patients. This study aims to determine changes in RGC and RNFL thickness in children with type 1 DM. Methods: This cross-sectional design analytical observational study was conducted at the eye polyclinic of Dr. M. Djamil General Hospital Padang in November 2023-March 2024. A total of 46 eyes from 46 people, divided into two groups: the type 1 DM group and the control group, were recruited in this study. RGC thickness was measured using AS-OCT GC-IPL thickness analysis and RNFL with optic disc RNFL thickness analysis. Data analysis was carried out using the unpaired T-test. Results: The results showed RGC depletion in the type 1 DM group (RGC 83.48 ± 3.75) compared to the control group (RGC 86.70 ± 4.87) with a value of p = 0.016 (p < 0.05). There was no statistical difference in RNFL thickness between the type 1 DM group (RNFL 102 ± 11.80) and the control group (RNFL 100.96 ± 10.97) with a value of p = 0.581 (p> 0.05). Conclusion: This study found RGC thinning in type 1 DM patients, but did not find differences in RNFL thickness between the two groups. This RGC depletion is thought to be caused by apoptosis of retinal neuronal cells due to chronic hyperglycemia. Examination of RGC thickness with OCT can be developed as an early detection of diabetic retinopathy in children with type 1 DM.
Myopia Progression in Children: A Comparative Analysis of Pre-Pandemic and Pandemic Periods Harsya Luthfi Anshari; Kemala Sayuti
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 1 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i1.1175

Abstract

Background: The COVID-19 pandemic brought about significant changes in children's lifestyles, including increased screen time and reduced outdoor activities due to school closures and lockdowns. These changes raised concerns about potential myopia progression in children. Methods: This study compared the spherical equivalent (SE) measurements of children aged 8-17 years from two time visits: one before the pandemic (September 2019 - February 2020) and one during the pandemic (March 2020 - February 2022). Data on family history of myopia, screen time, and outdoor activities were also collected. Paired t-tests were used to analyze the differences in SE between the two visits. Results: A total of 11 children participated in the study. The mean change in SE was -1.55 D, indicating a significant increase in myopia during the pandemic (p = 0.046). The average daily screen time was 201 minutes, while outdoor activity time was 42 minutes. Conclusion: The findings suggest a potential corelation between increased screen time, reduced outdoor activities, and myopia progression in children during the pandemic. It is crucial to encourage healthy visual habits, including limiting screen time and promoting outdoor activities, to mitigate the impact of the pandemic on children's vision.
KARAKTERISTIK KATARAK PADA DIABETES MELITUS DI RSUP DR. M DJAMIL PERIODE 2020-2021 Salsabila, Nada Shafa; Sayuti, Kemala; Lestari, Rahmi; Afriant, Rudy; Hendriati, Hendriati; Alioes, Yustini
SINERGI : Jurnal Riset Ilmiah Vol. 3 No. 2 (2026): SINERGI : Jurnal Riset Ilmiah, February 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v3i2.2357

Abstract

Cataracts are a condition in which the normally clear and clear lens of the eye turns cloudy. Cataracts that occur due to disorders of the endocrine system are caused by diabetes mellitus. This study aims to determine the characteristics of cataracts in diabetes mellitus at RSUP Dr. M Djamil Padang Period 2020 –2021. This research was a retrospective descriptive study with a cross-sectional approach to determine the characteristics of cataracts in patients with diabetes mellitus at RSUP Dr. M Djamil for the period 2020 - 2021. This study used secondary data in the form of medical records from 39 cataract patients with a history of diabetes mellitus. Data analysis was carried out in the form of descriptive analysis using the SPSS application. This study showed that 28 people (71.8%) respondents aged ≥ 60 years, 24 people were male (61.5%), 30 patients with duration of diabetes mellitus ≥5 years (76.9%), 19 respondents (48.7%) had mature cataracts. Individuals aged ≥ 60 years mostly had mature cataracts (14 people; 50.0%), male respondents mostly had mature cataracts (12 people; 50.0%) and individuals with cataract duration ≥ 5 years mostly had mature cataracts (17 people; 56.7%). The conclusion of this study is the discovery of cataracts in diabetes mellitus with the most age ≥ 60 years, male gender, duration of diabetes mellitus ≥5 years, and type of mature cataract. Most mature cataracts were found at age ≥ 60 years, male gender, and duration of diabetes mellitus ≥5 years.
Profil Pasien Katarak Kongenital di Poli Mata RSUP Dr. M. Djamil Padang periode 2020-2022 Kusumayanti, Ratna Dwi; Sayuti, Kemala; Akhyar, Gardenia; Hendriati, Hendriati; Afdal, Afdal; Anggraini, Fika Tri
Jurnal Ilmu Kesehatan Indonesia Vol. 7 No. 1 (2026): Maret 2026
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v7i1.1325

Abstract

Latar Belakang: Salah satu penyebab utama kebutaan pada bayi baru lahir dan anak-anak adalah katarak kongenital. Kekeruhan lensa sejak lahir ini dapat menghambat perkembangan visual dan berisiko menimbulkan ambliopia permanen bila tidak ditangani dini. Variasi etiologinya luas sehingga deteksi dini dan penatalaksanaan yang tepat menjadi sangat penting. Operasi yang dilakukan pada pasien katarak kongenital adalah Extra Capsular Cataract Extraction (ECCE) tanpa atau dengan pemasangan Intraocular Lens (IOL). Namun, pemasangan IOL jarang dilakukan pada anak di bawah usia 2 tahun. Objektif: Tujuan penelitian untuk mengetahui profil pasien katarak kongenital di Poli Mata RSUP Dr. M. Djamil Padang. Metode: Penelitian ini merupakan penelitian deskriptif retrospektif dengan teknik pengambilan sampel yaitu total sampling. Data rekam medis diperoleh dari 29 pasien yang terdiagnosis katarak kongenital pada periode 2020-2022 di Poli Mata RSUP Dr. M. Djamil Padang. Seluruh variabel dilakukan analisis univariat. Hasil: Hasil dari penelitian ini didapatkan kelompok usia katarak kongenital terbanyak 12-59 bulan (37,9%), sebagian besar berjenis kelamin laki-laki (62,1%) dan merupakan penderita katarak bilateral (72,4%). Infeksi intrauterin merupakan penyebab yang banyak ditemukan (44,8%), tetapi sebagian besar idiopatik (48,3%). Sebagian besar pasien katarak kongenital dilakukan prosedur ECCE tanpa IOL (61,5%). Kesimpulan:  Katarak kongenital sering terjadi pada usia 12-59 bulan, laki-laki, dan bersifat bilateral. Faktor idiopatik merupakan penyebab utama terjadinya katarak kongenital. Sebagian besar pasien ditatalaksana ECCE tanpa pemasangan IOL karena sebagian besar pasien berusia di bawah 2 tahun.
Co-Authors Adila Hanna Afdal Afdal Afdal Afdal, Afdal Agustin Vira Agustin Vira Andrini Ariesti Andrini Ariesti Anum, Qaira Astria Rima Rara Yuswir Astria Rima Rara Yuswir Azharudina, Adiba Azwin Aziz Deddy Saputra Desmawati Desmawati Devilen, Yuki San Elmatris Sy Ennesta Asri Ennesta Asri Erlina Rustam Febiyola Ratu Khairani Fika Tri Anggraini Fortuna, Fory Gardenia Akhyar Harmen Harmen Harsya Luthfi Anshari Hendriati Hendriati, Hendriati Hondrizal Hondrizal Husnil Kadri Ilahi, Fitratul Indah ARBR Tobing Indah Indria Sari Indah Indria Sari Izzati Mujahidah Julita Julita Julita Julita Kusumayanti, Ratna Dwi Lestari, Rahmi lonanda, Gama Agusto Martga Bella Rahimi Maya Nasrul Moestafa Nur Muhammad Syauqie Nabila Alifina Novian Novian Novian Novian Rahmadiansyah, Muhammad Fadhil Rahman, Harrie Kurnia Rendra Darma Satria Rendra Darma Satria Rika Desviorita Rika Desviorita Rina Gustia Rina Gustia Rinda Wati Rizki Dwayana Rizki Dwayana Rozy Oneta Rudy Afriant Rustam, Raihana Salsabila, Nada Shafa Sandiyanto Satya Wydya Yenny Suci Permata Sari Tofrizal Tofrizal Tutty Ariani Tutty Ariani Ulya Uti Fasrini Vitresia, Havriza Weni Helvinda Weni Helvinda Yanwirasti Yanwirasti Yustini Alioes