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HUBUNGAN KUALITAS TIDUR DENGAN FUNGSI KOGNITIF PADA MAHASISWA FAKULTAS KEDOKTERAN UNIVERSITAS SUMATERA UTARA Melly Leman; Lokot Donna Lubis; Milahayati Daulay; Cut Adeya Adella; Eka Roina Megawati
JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol 9 No 2 (2021): JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Volume 9.2 Edisi Agustus - No
Publisher : BAPIN-ISMKI (Badan Analisis Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53366/jimki.v9i2.474

Abstract

ABSTRACT Background: Sleep is an essential need in daily lives with abundant functions, especially neuron restoring process in neocortex after various activities. Poor sleep quality is often found, resulting from the needs of work, education, lifestyle, and sociocultural demand. It could hinder cognitive function thus affecting daily life quality. Thus, the objective of this study is to assess the risk factors of poor sleep quality and its relation to cognitive function of college students at Faculty of Medicine, Universitas Sumatera Utara. Method: This research uses an analytic method with cross-sectional design where the collection of data is simultaneously taken at one time. The data are primarily obtained from interviews utilising validated questionnaires, Pittsburgh Sleep Quality Index (PSQI) for sleep quality and Montreal Cognitive Assessment (MoCA) for cognitive function, with stratified random sampling technique. Results: The incidence of poor sleep quality of the samples is 69% with the predominance of being male, aged 17-19, having higher body mass index, and consuming caffeinated beverages. Meanwhile, the incidence of mild cognitive impairment is 42%. The Chi-Square and Spearman Rank tests show a significant relation (p=0.009) and weak correlation (r=0.262, p=0.008) between age groups and sleep quality, whereas there is no association of gender (p=0.517) and body mass index (p=0.322) with sleep quality. The Fisher’s Exact test yields no relation between consumption of caffeine (p=0.778) and sleep quality. According to the Chi-Square test, sleep quality is not associated with cognitive function as well (p=0.993). Conclusion. There is no association of sleep quality with cognitive function, however there is a significant relation and weak correlation between age groups and sleep quality.
IN VITRO EVALUATION OF PHYTOCHEMICAL COMPOUND FOR ANTIBACTERIAL ACTIVITY AT MURRAYA KOENIGII LEAF EXTRACT AGAINST THE GROWTH OF ESCHERICHIA COLI Elbert, Elbert; Adella, Cut Adeya; Faradina, Dwi; Lubis, Lokot Donna; Khosasi, Felix
JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol 11 No 1 (2024): JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol. 11.1 (2024)
Publisher : BAPIN-ISMKI (Badan Analisis Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53366/jimki.v11i1.767

Abstract

Introduction: In developing nations, like Indonesia, urinary tract infection, or UTI, is a frequent infection in women that results from the growth of microorganisms in the urinary tract. Escherichia coli is the most common cause. Antibiotics are the major form of treatment; however, misuse of these drugs has led to resistance. Innovation in potential medical plants is crucial. The curry leaf plant (Murraya koenigii) is one of them. Methods: The agar diffusion method was used to assess antibacterial activity. Murraya koenigii leaves were gathered from a garden in Tanjong Morawa. Escherichia coli ATCC 25922 is the type of bacteria that is used. Using 96% ethanol as the solvent, Murraya koenigii leaves were extracted using the maceration method. There were six treatments with concentrations of 6.25%, 12.5%, 25%, and 50%, positive control levofloxacin, and negative control DMSO. Results: The results of the phytochemical screening of the extracts showed that metabolites like flavonoids, tannins, and triterpenes had antibacterial effects. Data on the diameter of the inhibition zone were examined using the Kruskal-Wallis statistical test. The findings demonstrated that all treatments had statistically significant differences (p<0.05). Discussions: The presence of compounds such as flavonoids, tannins, and triterpenes in curry leaf extract has an antibacterial effect on Escherichia coli. This compound can prevent the creation of nucleic acids, inhibit cell membrane function, damage the permeability of bacterial cells, and deactivate bacterial enzymes. Conclusion: The ethanol extract of curry leaves has an inhibitory effect on the growth of Escherichia coli bacteria.
IN VITRO EVALUATION OF THE ANTIBACTERIAL POTENTIAL OF PSIDIUM GUAJAVA LEAF EXTRACT AGAINST ESCHERICHIA COLI: UNCOVERING THE ROLE OF PHYTOCHEMICAL COMPOUNDS. Khosasi, Felix; Adella, Cut Adeya; Faradina, Dwi; Lubis, Lokot Donna; Elbert, Elbert
JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol 10 No 3 (2024): JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol. 10.3 2024
Publisher : BAPIN-ISMKI (Badan Analisis Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53366/jimki.v10i3.765

Abstract

Introduction: Urinary tract infections (UTIs) are prevalent among women and are commonly caused by Escherichia coli. Although antibiotics are effective, their misuse contributes to rising antimicrobial resistance. Psidium guajava L., a traditional Indonesian medicinal plant, has shown promise as an alternative antibacterial agent. This study aimed to evaluate the inhibitory effect of P. guajava leaf extract against E. coli. Methods: Antibacterial activity was assessed using the agar diffusion method with E. coli ATCC 25922. Ethanolic extracts were obtained by maceration. Six treatment groups, including various concentrations of levofloxacin and dimethyl sulfoxide (DMSO), were tested to compare antibacterial effects. Results: Phytochemical screening revealed the presence of flavonoids, alkaloids, and tannins—compounds known for their antimicrobial activity. Inhibition zone diameters were measured and analysed using the Kruskal–Wallis one-way ANOVA. Discussion: The guava leaf extract demonstrated inhibitory activity against E. coli, likely due to its bioactive compounds. These constituents may exert antibacterial effects through disruption of nucleic acid synthesis, interference with membrane integrity, inhibition of energy metabolism, and prevention of biofilm formation. Conclusion: The ethanolic extract of Psidium guajava leaves exhibits significant antibacterial activity against Escherichia coli.
The Influence of Health Education on Knowledge and Attitude of Students of Dharma Pancasila Middle School About Menstrual Health Management Sitohang, Nur Asnah; Cut, Adeya Adella
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 7 No. 1 (2022): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (804.393 KB) | DOI: 10.32734/abdimastalenta.v7i1.4201

Abstract

Menstrual Hygiene Management (MHM) is the management of hygiene and health when women experience menstruation. The main problem in adolescents related to menstruation is the lack of knowledge about MSM and poor water sanitation. Many girls don't have the right understanding that menstruation is a normal biological process. Community service aims to improve students' knowledge and attitudes about menstrual health management. The method used is socializing; identify the state of menstrual health service facilities in schools: bathrooms, water, information; carry out bathroom renovations; provide educational media about menstrual health management in the form of posters, videos, leaflets, modules and flip sheets. Pre-test and post-test aims to identify students' knowledge and attitudes about menstrual health management. Analysis of the data used is the dependent t test. The knowledge of students before being given health education majority was in the sufficient category and thereafter increased to good. Likewise, students' attitudes increase to be positive. The statistical test results obtained mean difference of 7.72 and P Value = 0.001, it can be concluded that there is a significant effect of health education on knowledge. For attitudes the mean difference is 1.62 and the P value = 0.001, it can be concluded that there is a significant influence on health education on student attitudes. Therefore it is suggested to the school to include this topic in the subject matter. So students can apply it early and their reproductive health can be maintained.