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All Journal Jurnal Kedokteran Majalah Obstetri dan Ginekologi Health Notions Journal of Public Health Research and Community Health Development (JPH RECODE) AKSONA Folia Medica Indonesiana
Joni Wahyuhadi, Joni
Department Of Neuro-surgery, Faculty Of Medicine, Universitas Airlangga
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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Clinical Outcome of Patients with Diffuse Axonal Injury Receiving Adrenocorticotropin Analogue at Dr. Soetomo Hospital Wahyuhadi, Joni; Wicaksono, Pandu; Notobroto, Hari Basuki
Folia Medica Indonesiana Vol. 54, No. 3
Publisher : Folia Medica Indonesiana

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Abstract

Brain traumatic injury (BTI) is one of the causes of death and disability worldwide that affects people regardless of sex, age, income and social status, race, or nationality. In patients with brain traumatic injury, one of the problems that occurs is Diffuse Axonal Injury (DAI) that can produce a direct clinical effect, leading to coma and death. Adrenocorticotropin analogues (ACTH) is one of neuroprotective therapy in brain injury. The aim of this study was to analyze the effect of ACTH analogue on the clinical output (Glasgow Outcome Score/GOS and Bartle Index) in patients with DAI at hospital discharge, 3 months and 6 months post-treatment. This study revealed that ACTH analogue administration resulted in higher GOS and Barthel Index scores than that in control. Further study will required with other variables, such as cognitive and motor examination, and some biomarkers can also be examined serially.
A Model of Performance Evaluation for Healthcare Workers Based on Satisfaction and Remuneration (Financial and Non-Financial) Wahyuhadi, Joni; Hidayah, Nur; Aini, Qurratul
Folia Medica Indonesiana Vol. 58, No. 4
Publisher : Folia Medica Indonesiana

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Highlights: • This study aimed to formulate an evaluation model of the performance of health workers. • Employee performance targets and employee satisfaction were assessed by considering the financial and non-financial remuneration, Job Description Index (JDI), competencies, and motivation. • The performance evaluation model for health workers shows the importance of remuneration for government agencies, employees, and employee performance. Abstract: This study aimed to formulate an evaluation model of the performance of health workers from the perspective of financial and non-financial satisfaction and remuneration. The research method used was a literature study with a literature review approach. The research findings were the healthcare workers' performance evaluation model based on satisfaction and remuneration. The evaluation was conducted by assessing the employee performance targets (sasaran kerja pegawai/SKP) and employee satisfaction related to the financial and non-financial remuneration, Job Description Index (JDI), competencies, and motivation. In addition, this model has been also used for the evaluation of performance appraisal based on remuneration among employees (i.e. health workers) in government agencies, especially hospitals.
Case Report: Ventriculoperitoneal Shunt Catheter Migration and Transanal Extrusion in Persistent Vegetative State Adult Patient Fauzi, Asra Al; Parenrengi, Muhammad Arifin; Wahyuhadi, Joni; Subagio, Eko Agus; Turchan, Agus
Folia Medica Indonesiana Vol. 55, No. 4
Publisher : Folia Medica Indonesiana

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Abstract

Hyaluronic acid (HA) is a glycosaminoglycan with a straight-chain polymer arrangement defined as the extracellular matrix constituent. High molecular weight HA has normal physicochemical, biological, and physiological properties whereas low molecular weight has the property of angiogenesis, inflammation, and suppresses apoptosis. This study occupied the samples of 35 paraffin block from poorly and well differentiated retinoblastoma tissue and 8 normal retinal block which have been collected for 4 years from 2010-2013 at Dr. Soetomo Hospital, Surabaya, Indonesia. Afterwards, the paraffin blocks were immunohistochemically examined for HA staining, expression of cell proliferation (Ki-67), and cell apoptosis to determine intratumoral aggressiveness of retinoblastoma. HA on poorly differentiated retinoblastoma stain with a high immunostaining of 76.2%, while well differentiated retinoblastoma on the highest HA staining was revealed to be at moderate level of 64.3%, and not appear in normal retina. In poorly differentiated retinoblastoma, the location of most HA stain is in the cell cytoplasm (87.5%). In the well differentiated retinoblastoma, the HA immunostaning mainly occurred in the cell membrane (73.7%). Histopathological retinoblastoma grading showed a significant correlation (p <0.01) towards several variables of HA immunostaining, Ki-67, and cell apoptosis. In addition, the histopathological retinoblastoma grading also revealed a significant correlation (p <0.01) towards the location of HA staining (cell membrane and cytoplasm). Both stainings are also play role in retinoblastoma differentiation. The malignancy of retinoblastoma can be proven by the increased HA staining at cytoplasm in poorly differentiated and associated with increased of cell proliferation along with decreased apoptosis.
Co-Authors Arlia Ayu Damayanti Damayanti, Arlia Ayu Endang Warsiki Endang Warsiki dan Citra Dewi Wahyono Putri (E-Jurnal Agro-Industri Indonesia) Fauzi, Asra Al Haq , Irwan Barlian Immadoel Hari Basuki Hari Basuki Notobroto Heryani, Dini I Gusti Ayu Indah Ardani J Mukono Komang Wahyu Kurniawan Mukono, H J Nur Hidayah Nur Hidayah Pandu Wicaksono Pandu Wicaksono Parenrengi, Muhammad Arifin Puspikawati, Septa Indra Qurratul Aini Qurratul Aini R. Yuvasanghar Ravindra Mohan Ramadhaningtyas , Erica Medina Rohadi Rohadi Sari, Erni A Setiawati, Yunias Sri Andreani Utomo, Sri Andreani Subagio, Eko Agus Suharjono, Suharjono Susilo, Rahadian Indarto Tedy Apriawan Tirthaningsih, Ni Wajan Turchan, Agus Viskasari P. Kalanjati