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All Journal Jurnal Pengolahan Hasil Perikanan Indonesia Jurnal FishtecH Panggung Marinade Jurnal Ilmu Kefarmasian Indonesia Indonesian Journal of Health Science Journal of Pharmaceutical and Sciences. PROSIDING SEMINAR NASIONAL PENELITIAN DAN PENGABDIAN KEPADA MASYARAKAT (SNPPM) UNIVERSITAS MUHAMMADIYAH METRO Jurnal Pengabdian Masyarakat Nian Tana Journal of Medicine and Health ISTA Online Technologi Journal
Nurfitriyana Nurfitriyana
Department Of Pharmacy, Faculty Of Mathematics And Natural Sciences, Universitas Sriwijaya, Indralaya, Sumatera Selatan, Indonesia
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Determination of total alkaloid content in 70% and 96% ethanol extracts of red seaweed (Eucheuma spinosum) obtained by maceration using UV-Vis spect Sindi Arlin Natasya; Dwi Kurnia Putri; Rose Intan Perma Sari; Samwilson Slamet; Putri Mulia; Nurfitriyana Nurfitriyana
Indonesian Journal of Health Science Vol 6 No 3 (2026)
Publisher : PT WIM Solusi Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54957/ijhs.v6i3.2261

Abstract

Red seaweed (Eucheuma spinosum) is one of the marine biological resources containing various secondary metabolites, including alkaloids which possess important biological activities. Differences in ethanol concentration may affect the amount of alkaloid compounds extracted. This study aimed to compare the alkaloid content of 70% ethanol extract and 96% ethanol extract of red seaweed (Eucheuma spinosum) obtained by maceration using the UV-Visible spectrophotometric method. This research was conducted experimentally in the laboratory using the maceration extraction method with 70% and 96% ethanol solvents. Qualitative identification of alkaloids was performed using Mayer, Wagner, and Dragendorff reagents, while quantitative determination was carried out using UV-Visible spectrophotometry with caffeine as the standard at a maximum wavelength of 275 nm. Phytochemical screening results indicated that both 70% and 96% ethanol extracts were positive for alkaloid compounds. The extraction yield of the 70% ethanol extract was 22.945%, whereas the 96% ethanol extract yielded 12.45%. The results of alkaloid determination showed that the 70% ethanol extract contained an average alkaloid level of 5.5 ± 0.22 mg QCE/g, while the 96% ethanol extract contained 5.3 ± 0.10 mg QCE/g. It can be concluded that the 70% ethanol extract produced a slightly higher alkaloid content than the 96% ethanol extract of red seaweed (Eucheuma spinosum).
ANALISIS SENYAWA BIOAKTIF DAN AKTIVITAS ANTIOKSIDAN EKSTRAK RUMPUT LAUT Boergesenia forbesii MENGGUNAAN PELARUT YANG BERBEDA Rini Yanuarti; Rima Rizqy Ramadhanty; Nurfitriyana Nurfitriyana
Marinade Vol 8 No 02 (2025): Oktober, 2025
Publisher : Fisheries Product Technology Department, Faculty of Marine Science and Fisheries, Universitas Maritim Raja Ali Haji

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31629/marinade.v8i02.7762

Abstract

Rumput laut merupakan salah satu jenis makroalga yang banyak sekali tumbuh dan berkembang di daerah perairan pesisir. Kandungan bahan aktif seperti antibakteri dan antioksidan yang banyak ditemukan pada rumput laut. Tujuan dari penelitian ini yaitu untuk mengetahui aktivitas antioksidan rumput laut Boergesenia Forbesii yang diekstraksi dengan tiga pelarut yang berbeda yaitu N-Heksan, etil asetat dan etanol. Penelitian ini dilakukan dengan melihat perbedaan pelarut yang digunakan untuk proses ekstraksi pada rumput laut Boergesenia forbesii untuk mengetahui skrining fitokimia, uji kadar air, uji kadar abu dan uji aktivitas antioksdian. Hasil pengujian fitokimia pada ekstrak rumput laut Boergesenia forbesii dengan menggunakan 3 pelarut diperoleh hasil positif pada setiap senyawa (alkaloid, flavonoid, saponin, tanin, steroid, fenol dan glikosida). Hasil kadar air dan kadar abu semua ekstrak rumput laut dinyatakan aman dan baik karena tidak melebihi dari persyaratan parameter standar. Hasil analisis antioksidan menunjukkan bahwa aktivitas antioksidan ekstrak rumput laut Boergesenia forbesii yang diekstrak menggunakan pelarut N-Heksan, etil asetat dan etanol 96% memperoleh nilai IC₅₀ berturut-turut 137,264 ppm, 112,649 ppm, dan 99,44119 ppm. Hasil tersebut menunjukkan bahwa ekstrak rumput laut Boergesenia forbesii yang diekstrak menggunakan pelarut etanol yang memiliki aktivitas antioksidan kuat (IC₅₀ 99,44119 ppm).
Uji Aktivitas Antioksidan Teh Herbal Biji Durian (Durio zibethinus Murr.) dengan Tambahan Daun stevia (Stevia rebaudiana Bertoni) sebagai Pemanis Alami dengan Metode DPPH Muhammad Andry; Tiara Ramadaini; Cindy Marseli; Nurfitriyana Nurfitriyana; Rafifah Azzahra; Hafid Syahputra; Shaum Shiyan
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 4 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i4.1070

Abstract

Free radicals are an important health concern due to their role in the development of various diseases. Antioxidants, capable of neutralizing free radicals, are abundant in plants such as durian seeds (Durio zibethinus Murr.) and stevia leaves (Stevia rebaudiana Bertoni). Herbal tea formulated from these materials has potential as an alternative functional drink because both contain phenolic compounds with antioxidant activity. This study aimed to evaluate the potential of durian seeds and stevia leaves as herbal tea with antioxidant properties. The research involved sample collection, identification, preparation of simplicia, characterization, formulation of herbal tea, quality testing, and determination of antioxidant activity. The simplicia characteristics of durian seeds and stevia leaves showed water content of 6.16% each, water-soluble extract of 35% and 15.8%, ethanol-soluble extract of 25.5% and 14.6%, total ash of 0.73% and 0.3%, and acid-insoluble ash of 0.5% and 0.26%. Quality testing of the herbal tea showed water content of 2.18%, total ash of 3.90%, water-soluble ash of 73.85%, and acid-insoluble ash of 3.80%. Antioxidant activity based on IC50 values was 68.45 ± 1.32 ppm for durian seed tea, 61.6 ± 1.05 ppm for stevia tea, 39.28 ± 0.98 ppm (1:1), 44.64 ± 1.11 ppm (1:2), and 42.32 ppm ± 1.07 (2:1). These results indicate that combining durian seeds and stevia leaves can enhance antioxidant activity compared to individual extracts. Overall, durian seeds and stevia leaves can be developed into herbal tea formulations with very strong antioxidant activity, as reflected in their ability to reduce DPPH radicals. Radikal
Co-Authors : Samwilson Slamet, : Samwilson Abdul Gofar S ANDRI ARTHONO Aris Munandar BABAY JUTIKA CAHYANA Chandra Tresnadi Chriswahyudi, Chriswahyudi Cindi Septiani Devi Yulikasari Diah Kusmardini Dwi Citra Septiana Dwi Kurnia Putri Dyah Ayuwati Waluyo Ekadipta Ekadipta Fitria Fitriya Fitriya Ginanjar Pratama Ginanjar Pratama Ginanjar Pratama Hafid Syahputra Hardiyanti Syarif Iin Hardiyati In Rahmi Fatria Indri Dyah Pangesti Itok Dwi Kurniawan July Ivone Kahdar, Khafiati Marseli, Cindy Muhammad Andry Muhammad Zuhriyanto Najma Annuria Fithri Najma Annuria Fithri Pramusinto Adhy Pratiwi, Annisa Nurul Putri Mulia Rafifah Azzahra Ratuannisa, Tyar Rima Rizqy Ramadhanty Rindu DS Pitaloka Rini Yanuarti Rini Yanuarti Rini Yanuarti Rini Yanuarti Rini Yanuarti Rose Intan Perma Sari Sakinah Haryati Shafa Tasha Salsadillah Shaum Shiyan Sindi Arlin Natasya Siti Marwah Lestari Tiara Ramadaini