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Therapy of Dequalinium Chloride Vaginal Tablets in Pregnant Women with Vulvovaginal Candidiasis Setyowatie, Lita; Larasaty, Nanda Shaskia
Indonesian Journal of Obstetrics and Gynecology Volume 13. No. 4 October2025
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v13i4.2296

Abstract

Background: Vulvovaginal candidiasis (VVC) is a Candida infection on vulva and vagina region. The most common etiology is C. albicans. Besides being the risk factor for developing VVC, pregnancy also limits the possible medication. This report presents the efficacy of Dequalinium Chloride (DQC) on VVC during pregnancy due to C. albicans. Case: A third-trimester primigravidae, 27-year-old, complained first odorless thick curd-like consistency vaginal discharge accompanied with pruritus (VAS 9/10) and pain since 3 months prior to admission. Venerology examination showed erythema on the labia majora and a great amount of thick vaginal discharge on the labia minora, vaginal, and cervix area. Vaginal discharge examination using KOH 10% showed pseudohyphae. Gram examination found pseudohyphae and polymorphonuclear (PMN) cells >30 in the vagina, and pseudohyphae on the cervix’s discharge. VITEK-2 culture showed fluconazole-sensitive C. albicans. The patient was given DQC intravaginal tablets for 10 days and showed remarkable clinical and microscopic examination improvement. Conclusion: Intravaginal DQC is effective in treating pregnant patients with VVC. VVC in pregnancy should be treated appropriately to prevent perinatal adverse effects. Keywords: Vulvovaginal Candidiasis, dequalinium chloride, pregnancy, C. albicans
A MULTIDISCIPLINARY APPROACH TO A CASE OF CONDYLOMA ACUMINATA IN AN ADOLESCENT FEMALE FOLLOWING SEXUAL ABUSE – CASE REPORT Sakinah, Dyah Ayu; Setyowatie, Lita
Journal of Psychiatry Psychology and Behavioral Research Vol. 7 No. 1 (2026): Multidimensional Perspectives on Mental Health Across the Lifespan and Social C
Publisher : Departemen Psikiatri Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jppbr.2026.007.01.8

Abstract

Introduction: Condyloma acuminata (CA) is a sexually transmitted disease caused by human papillomavirus (HPV) and typically presents as exophytic, verrucous lesions on moist mucocutaneous surfaces, including the anogenital region. The infection is highly transmissible and may occur as solitary or multiple lesions of varying sizes. In pediatric and adolescent populations, the identification of sexually transmitted infections may represent an early clinical indicator of sexual abuse. The aim of this report to highlight the role of a multidisciplinary approach in comprehensive patient management. Methods: A 15-year-old female presented with genital warty lesions. Dermatovenereological examination revealed multiple skin-colored verrucous papules involving the labia majora and minora, without tenderness or bleeding. Detailed anamnesis obtained from the patient and her caregiver disclosed a history of sexual abuse. The clinical diagnosis was confirmed by histopathological examination of biopsied lesions. Results: The patient was diagnosed with condyloma acuminata associated with HPV infection in the context of sexual abuse. Management involved collaboration among dermatovenereologists, pediatricians, psychiatrists, and pediatric surgeons to address both medical conditions and psychological trauma. Discuss: Management of this patient required a multidisciplinary approach involving pediatrics for underlying aplastic anemia, dermatovenereology for genital warts, psychiatry for psychological trauma, and pediatric surgery for definitive lesion management. Such coordinated care was essential to address both the medical and psychosocial complexities associated with condyloma acuminata following adolescent sexual abuse. Conclusion: The presence of condyloma acuminata in children or adolescents should prompt careful evaluation for possible sexual abuse. Early diagnosis and coordinated multidisciplinary management are crucial to achieving optimal medical treatment and psychological recovery.  Keywords: pseudobulbar affect, stroke, antidepressant.