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Ulfa Husnul Fata
Sekolah Tinggi Ilmu Kesehatan Patria Husada Blitar
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The Moderating Role of Drinking Water Habit on the Effect of High- Purine Dietary Intake on Uric Acid Levels in Adults and the Elderly Rahmawati, Anita; Lestari, Amelia Anggi Dwi; Fata, Ulfa Husnul
Journal of Ners and Midwifery Vol 12 No 3 (2025)
Publisher : STIKes Patria Husada Blitar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26699/jnk.v12i3.ART.p259-269

Abstract

Serum uric acid levels are affected by dietary patterns and lifestyle factors. High-purine food consumption is a primary contributor to hyperuricemia, while hydration status may moderate this effect. This study aimed to examine the moderating role of drinking water habits on the relationship between high-purine dietary intake and serum uric acid levels among adults and the elderly. A cross-sectional design with purposive sampling was conducted, involving 87 respondents from Elderly Integrated Health Post (Posyandu Lansia). Data on purine-rich food intake and water-drinking habits were collected via structured questionnaires, and serum uric acid levels were measured using a point-of-care testing (POCT) device (Easy Touch GCU 3-in-1) with compatible test strips. Multiple logistic regression analysis assessed the interaction between purine intake and drinking water habits. Results revealed a significant association between high-purine dietary intake and elevated serum uric acid levels (p = 0.022). Participants who reported high-purine dietary habits along with insufficient water consumption demonstrated the highest prevalence of hyperuricemia (71.4%), whereas those with similar dietary patterns but adequate hydration showed a substantially lower prevalence (20.0%). A significant interaction effect (p = 0.040) indicated that sufficient water intake moderated the impact of a high-purine diet on uric acid levels. Adequate hydration thus plays a critical moderating role in reducing the adverse effects of a high-purine diet. Promoting sufficient water intake may serve as a simple and effective behavioral strategy to prevent hyperuricemia, particularly among individuals with high purine consumption.
Co-Authors Anita Rahmawati Anita Rahmawati Anita Rahmawati Arsa, Sandi Alfa Wega Ayu Rahmawati Bisepta Prayogi Bisepta Prayogi, Bisepta Danang Candra Wiratama Elok Dwi Mamiri Erni Setiyorini Erni Setiyorini, Erni Ferry Efendi hastutik, annasikah sustyo Hipolito Da Cruz Soares ika agustina Ila Ageng Safiani Inosensia Amtonis Inosensia Amtonis, Inosensia Jamhari Jamhari Kuswidyarti, Yulia Laily Prima Monica Laily Prima Monica Laily Prima Monica, Laily Prima Lestari, Amelia Anggi Dwi Levi Tina Sari, Levi Tina Lury Trijayanti Lutvi Febriana Maisari, Krista Mamiri, Elok Dwi Maratus Sholichah Fitriah Hajar Kusnianto Maria Ulfa Maria Ulfa Murti, Rahma Nawang Wulandari Nawang Wulandari Nawang Wulandari, Nawang Ning Arti Wulandari, Ning Arti Noviasari, Ita Nursalam, Nursalam Raden Roro Dewi Rahmawati Aktyani Putri Rahmawaty, RR Dewi Rihardini, Natalusia Romadhon, Wimar Anugrah Shinta Wulandari, Shinta Thatit Nurmawati, Thatit Trijayanti, Lury Viramita, Afifah Wahyu Wibisono WAHYU WIBISONO Wiga, Sandi Alfa Wiratama, Danang Candra Yeni Kartika Sari, Yeni Kartika Yulia Kuswidyarti