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All Journal Borobudur Pharmacy Review Jurnal Permata Indonesia Jurnal Pengabdian Masyarakat Permata Indonesia Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan Jurnal Komunitas Farmasi Nasional Jurnal Medicare The Journal General Health and Pharmaceutical Sciences Research Science Techno Health Journal
Jarot Yogi Hernawan
Politeknik Kesehatan Permata Indonesia Yogyakarta
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary Other

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Pola Penggunaan Antibiotik Pada Pasien Pneumonia Dewasa Rawat Inap RSU PKU Muhammadiyah Bantul Periode Tahun 2022 Mithasari Hutami; Hanita Christiandari; Jarot Yogi Hernawan
An-Najat Vol. 2 No. 1 (2024): FEBRUARI : An-Najat: Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v2i1.663

Abstract

The prevalence of pneumoniae deaths in the world is around 2.56 million people in 2017. Based on the 2018 Riskesdas data, in Indonesia there has been an increase in the prevalence of pneumonia at all ages from 1.6% (2013) to 2.0% (2018). Pneumonia is an inflammation of the lungs that causes pain when breathing and limits oxygen intake. Pneumonia is caused by bacteria, viruses or mycoplasma. Antibiotics are the main drug in the management of infectious diseases. Adult patients are the groups most at risk for pneumoniae. Purpose: Knowing the pattern of antibiotic use in hospitalized adult pneumonia patients at RSU PKU Muhammadiyah Bantul for the 2022 period. This research is a non-experimental descriptive study. The sample used was 170 patients. Recording of patient data includes the patient's RM number, gender, age, drug given. Data were processed and analyzed descriptively, then calculated in percentage form and presented in tabular form. Results the research it showed the results of patients with an inpatient diagnosis of pneumonia dominated by men 59% and the elderly group 65%. The most widely used class of antibiotics were cephalosporin 36.65%, macrolide 33.22% and quinolones 22.95%. The most widely used antibiotic names were azithromycin 33.22%, ceftriaxone 23.63%, and levofloxacin 19.18%. The most common route of administration of antibiotics was the parenteral route 83% and the oral route 17% with the longest duration of administration of antibiotics for 3 days 47%, 5 days 36%, 7 days 12%, and 5% for administration of antibiotics > 7 days. Conclusion: Patients diagnosed with adult pneumoniae were dominated by 59% of men and 65% of the elderly group. The most widely used class of antibiotics was cephalosporins at 36.65%. The most widely used parenteral antibiotic was azithromycin at 33.22% with the longest duration of antibiotics being 3 days at 47%.
AKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL DAUN SEMANGGI AIR (Marsilea crenata) PADA MENCIT PUTIH (Mus musculus L.) DENGAN INDUKSI KARAGENIN Siti Fatimah; edy suprasetya; Jarot Yogi Hernawan
Jurnal Permata Indonesia Vol 15 No 1 (2024): Volume 15, Nomor 1 Tahun 2024
Publisher : Politeknik Kesehatan Permata Indonesia Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59737/jpi.v15i1.289

Abstract

Inflammation is a complex biological response to stimulation that damages tissue with signs such as erythema (redness), dolor (heat), edema (swelling) and pain. Water clover (Marsilea crenata) has phytochemical compounds in the form of reducing sugars, steroids, carbohydrate content, and flavonoids as antioxidant agents. The aim of the research was to determine the anti-inflammatory activity of ethanol extract of water clover leaves (Marsilea crenata) as a natural antioxidant in white mice (Mus musculus L.) with carrageenin induction. The samples in this study were water clover leaves (Marsilea crenata) and were tested on white mice with different extract doses. The research was experimental using a completely randomized design (CRD) with different concentrations of extract doses and the movement of mice was observed. The stretching data was analyzed statistically using the one way ANOVA test with a confidence level of 95% (α=0.05) if there was significance, followed by the Tukey test to determine the differences between concentration treatments. The results showed that the percentage of anti-inflammatory protection from the negative control group was 61.14%, the 50 mg/kgBB dose group was 22.82%, the 100 mg/kgBB dose extract group was 37.14%, and the 200 mg/kgBB dose group was 70.15%. %. From these results it is known that the antioxidant activity of the ethanol extract of water clover (Marsilea crenata) with an extract dose of 200 mg/kgBW showed the best activity compared to other doses. Keyword : water clover, anti-inflammatory, percent protection
FORMULASI SEDIAAN KAPSUL PENAMBAH NAFSU MAKAN EKSTRAK KUNYIT (Curcuma Domestica) Jarot Yogi Hernawan; Hanita Christiandari; Febliana Putri
Jurnal Permata Indonesia Vol 15 No 1 (2024): Volume 15, Nomor 1 Tahun 2024
Publisher : Politeknik Kesehatan Permata Indonesia Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59737/jpi.v15i1.302

Abstract

Kapsul penambah nafsu makan sebagai salah satu cara mengatasi sulit makan anak. Tanaman yang dapat dimanfaatkan sebagai kapsul penambah nafsu makan adalah tanaman kunyit (Curcuma domestica). Penelitian ini bertujuan untuk mengetahui hasil fisik formulasi sediaan kapsul penambah nafsu makan ekstrak kunyit (Curcuma domestica). Jenis penelitian yang digunakan adalah eksperimental, dengan perbedaan konsentrasi ekstrak kunyit (Curcuma domestica) FI (30 %), FII(40 %), FII (50 %). Evaluasi fisik kapsul penambah nafsu makan yang dilakukan meliputi organoleptis, homogenitas, keseragaman bobot. Uji fisik kapsul penambah nafsu makan pada organoleptis menghasilkan FI warna kuning muda, FII kuning kecoklatan, FIII kuning tua, berbentuk serbuk, bau khas kunyit, dan rasa pahit. Hasil homogenitas pada FI, FII, FIII sediaan kapsul penambah nafsu makan tidak menujukan adanya partikel kasar pada sediaan. Hasil keseragaman bobot pada FI, FII, FIII sediaan kapsul penambah nafsu makan menujukan bahwa tidak ada 2 kapsul yang bobotnya menyimpang lebih dari 7,5 % dan tidak ada satupun yang bobotnya menyimpang lebih dari 15 % dari bobot rata-ratanya. Formulasi sediaan kapsul penambah nafsu makan dapat disimpulkan bahwa formulasi I, formulasi II, formulasi III dengan konsentrasi 30 %, 40 %, 50 % menghasilkan sediaan yang baik. Pada formulasi II memenuhi evaluasi fisik pada organoleptis berwarna kuning kecoklatan, homogenitas tidak adanya partikel kasar pada sediaan, keseragaman bobot.
Uji Efektivitas Formulasi Lip Balm Ekstrak Buah Alpukat (Persea Americana Mill) Sebagai Pelembab Bibir Hanita Christiandari; Jarot Yogi Hernawan; Rima Melati Dwi Utami3
Science Techno Health Journal Vol. 2 No. 2 (2024): Science Techno Health Journal
Publisher : Science Techno Health Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Latar belakang: Ekstrak buah alpukat terdapat kandungan karbohidrat, protein, lemak, vitamin A, vitamin B, vitamin C, vitamin D,dan vitamin E. Vitamin E juga dikenal sebagai vitamin yang berguna untuk menghaluskan kulit. Selain lipstik kosmetik bibir yang digunakan wanita adalah lip balm. Lip balm dirancang untuk melindungi dan menjaga kelembapan bibir. Campuran vitamin E dan vitamin A sangat berperan dalam perawatan kulit. Kombinasi ini dapat membantu kulit menjadi kenyal, menghilangkan kerut dan membuat kulit terlihat segar. Tujuan: Mengetahui keefektifan dari ekstrak buah alpukat (Persea americana Mill) sebagai lip balm. Metode: Jenis penelitian yang digunakan adalah eksperimen. Desain penelitian Post-test Control. Hasil: Hasil penelitian dari ketiga konsentrasi ekstrak buah alpukat 2%, 4%, dan 8% dengan 4 macam uji. Uji organoleptis untuk ketiga konsentrasi tidak mengalami perubahan warna, bentuk, dan aroma. Uji homogenitas untuk ketiga konsentrasi bersifat homogen. Uji ph ketiga kosentrasi berada pada rentang 5-6. Uji suhu lebur sediaan ketiga konsentrasi berada pada rentang 55°C-56,7°C. Kesimpulan: Buah alpukat dapat diformulasikan menjadi lip balm dengan konsentrasi 8% dengan perbandingan formula kontrol.
Formulasi Sediaan Serum Antioksidan dari Ekstrak Sari Tomat (Solanum Lycopersicum L.) sebagai Perawatan Kulit Hanita Christiandari; Intan Kumalawati; Jarot Yogi Hernawan
An-Najat Vol. 3 No. 3 (2025): Agustus : An-Najat : Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v3i3.3185

Abstract

Skin damage occurs because free radicals lose one electron in their outer orbit so that they are highly reactive which can cause oxidative stress. The impact is damage to body cells, such as large pores, acne, wrinkles and dark spots. Free radicals can come from the metebolism process in the body and from outside the body. One preparation that can prevent skin damage is a serum that contains antioxidants. To determine the physical properties, namely organoleptics, homogeneity, pH, spreadability, and adhesiveness of tomato juice extract (Solanum lycopersicum L.) serum preparations. The type of research used is experimental. The sample used was tomato juice extract. The research was conducted at the Pharmacy Laboratory of Politeknik Permata Indonesia Yogyakarta in May-June 2024. The independent variables of this study were 2%, 4%, 6% tomato juice extract. The dependent variable in this study is the test of physical properties of serum preparations including organoleptical tests, homogeneity, pH, spreadability, and adhesiveness. Data analysis in this method uses One way ANOVA. Organoleptical results are viscous, clear, clear yellow, light brown to dark brown in color and smells rose. The homogeneity results of the three formulations are homogeneous. The pH value in F0 was 5.08; F1 was 5.20; F2 was 5.35; F3 was 5.51. The value of spreadability in F0 was 5.2cm; F1 was 5.78cm; F2 was 5.91cm; F3 was 6.23cm. The stickiness value in F0 was 8.82; F1 was 15.94; F2 was 23.11; F3 was 30.75. All formulas have organoleptical arrangement, homogeneity, pH, spreadability, and adhesiveness that meet the requirements. Serum preparation of tomato juice extract (Solanum lycopersicum L.) has eligible physical properties.
PERAN TINGKAT PENDIDIKAN TERHADAP PENGETAHUAN PENYIMPANAN DAN PEMBUANGAN OBAT DI RUMAH PADA PASIEN RAWAT JALAN RSI SUNAN KUDUS Pratiwi, Yulia; Khoiriyah; Annis Rahmawaty; Dian Arsanti Palupi; Rifda Naufa Lina; Jarot Yogi Hernawan
Jurnal Medicare Vol. 4 No. 3: JULY 2025
Publisher : Rena Cipta Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62354/jurnalmedicare.v4i3.240

Abstract

Improper storage and disposal of medications at home can reduce drug quality, pose risks of poisoning, and contribute to environmental pollution. However, public knowledge remains low, as only 16.1% of respondents demonstrated good understanding of proper storage, and 52.6% lacked awareness of safe disposal methods. Education is considered a key factor in improving health literacy related to medication management. This study aimed to examine the relationship between educational level and knowledge of medication storage and disposal among outpatients at RSI Sunan Kudus. The research employed a descriptive quantitative approach, involving 392 respondents selected through purposive sampling. Data were analyzed using univariate analysis and Spearman Rank correlation. The majority of respondents were female (71.4%), aged 26–45 years (47.2%), had a senior high school/vocational education (53.8%), and were employed in the private sector (56.9%). Most respondents had moderate knowledge regarding storage (55.4%) and disposal (44.6%) of medications. A significant relationship was found between education level and knowledge of both storage (r = 0.532; p < 0.001) and disposal (r = 0.610; p < 0.001). More intensive education by pharmaceutical staff is recommended.
Co-Authors Aglita Janis Rupita Aglita Janis Rupita Annis Rahmawaty Aprilia Siti Nur Hidayyah Ayu Puji Lestari Christiandari, Hanita Cristin Wiji Astuti Dian Arsanti Palupi Edi Suprasetya Estika Sonia Febliana Putri Hari Kurniawan Intan Kumalawati Khoiriyah Mithasari Hutami Prita Swandari riansih, chici Rifda Naufa Lina Rima Melati Dwi Utami3 Rosa Rosa SITI FATIMAH Yulia Pratiwi