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Review of Secondary Metabolites From Melandean Bark Extract (Bridellia Micrantha): Bioactive Potential and Applications in Health Bayani, Faizul; Muhali, Muhali; Yuliana, Devi; Hulyadi, Hulyadi; Gargazi, Gargazi
Hydrogen: Jurnal Kependidikan Kimia Vol. 12 No. 3 (2024): June-July 2024
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/hjkk.v12i3.11956

Abstract

Abstract The emergence of various diseases affecting the immune system, such as COVID-19 and Hand, Foot, and Mouth Disease, demands serious attention. Current climate changes occurring in almost all parts of the world can lead to the emergence of various viruses and bacteria that cause multiple diseases. Exploring medicinal plants that can enhance the immune system is crucial to be continued. This study aims to identify secondary metabolite compounds contained in Bridellia Micrantha plants using chemical reagents and gas chromatography-mass spectrometry (GC-MS) instruments. This research is an experimental laboratory study. The variable studied is the content of secondary metabolite compounds. Data were collected using chemical reagents and instruments. The obtained data are described in informative tables and graphs. Based on the identification results using instruments, positive results were found for organic compound groups such as flavonoids, alkaloids, and tannins. GC-MS test results showed that the organic compounds  contained in Bridellia Micrantha extract are 43.05% hexadecanoic acid, 21.46% oleic acid, 16% docos-13-enoic acid, 3.89% octadecanal, 1.85% propanediol, and 0.91% trans-phytol. Literature reviews indicate that the organic acids in Bridellia micrantha extract have clinical activities as antioxidants and anti-inflammatory agents, while organic compounds containing hydroxyl groups have clinical activities as anti-cancer agents. Based on these findings, Bridellia micrantha extract has the potential as a medicine that can enhance the body's immunity.  
Antioxidant Activity Analysis of Ethanol Extract from Melandean Leaves (Bridelia micrantha) Using the DPPH Assay Bayani, Faizul; Rahayu, Lale Budi Hutami; Rahayu, Supiani; Huaida, Nurul; Yuliana, Depi; Hulyadi, Hulyadi; Gargazi, Gargazi
Hydrogen: Jurnal Kependidikan Kimia Vol. 12 No. 6 (2024): December 2024
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/hjkk.v12i6.13855

Abstract

The increasing global prevalence of oxidative stress-related diseases such as cardiovascular disease, diabetes, and neurodegenerative disorders underscores the importance of developing effective antioxidant strategies. In this study, samples of ethanol extract from Bridelia micrantha (Melandean) leaves were used which were then evaluated using the DPPH (2,2-diphenyl-1-picrylhydrazyl) test, a method that is widely known for assessing free radical scavenging activity. The ethanol extract sample was obtained through maceration with a yield of 15.84%. Based on the DPPH test, it shows that the extract has dose-dependent inhibition of DPPH radicals, with a maximum inhibition of 66.13% at a concentration of 25 ppm. The IC50 value, calculated from regression analysis, confirmed the antioxidant potential of the extract, although it was less effective than that of vitamin C, which was used as a positive control. These findings suggest that Bridelia micrantha leaves, rich in phytochemicals such as flavonoids, tannins, and saponins, have the potential as a source of natural antioxidants for managing oxidative stress-related health conditions.
Correlation Profile of Cognition Levels and Student Ability to Solve Problems in Biodiesel Synthesis Hulyadi, Hulyadi; Bayani, Faizul; Muhali, Muhali; Khery, Yusran; Gargazi, Gargazi
Jurnal Penelitian Pendidikan IPA Vol 9 No 6 (2023): June
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i6.3130

Abstract

Covid-19 has had a huge impact in all sectors. The socio-economic sector experienced the heaviest impact. One of the sectors affected is the world of education. Education is now transforming from face-to-face learning to online learning. Online learning is very helpful for students during covid-19. In addition to having a positive value, online learning also contains a negative value. For example, students' interest in reading increases, but on the other hand, students' reading power is low. Low reading power has an impact on decreasing the cognitive level of students. The purpose of this research is to first identify the cognitive level profiles and students' abilities in solving problems in the synthesis of biodiesel from used cooking oil. Analyzing the correlation between cognitive level and students' ability to solve problems. This research is a correlational descriptive research. This research was conducted on fourth semester chemistry education students who were taking an instrument chemistry course and determining the structure of organic compounds. Cognitive level and problem-solving ability were measured using a rubric for assessing cognitive level and student problem-solving ability. The data obtained is then described in graphical form. The data was then tested for correlation using the SPSS product moment correlation test. In this study, it was found that the cognitive level of most students entered at C2 and C3 levels and the average problem solving ability was 53.84. The results of the correlation test show that the cognitive level is positively correlated with the ability of students to solve problems. This is evidenced by the comparison of the value of r count 0.724> r table 0.44. Based on the results of this study, it can be concluded that the cognitive level and problem solving abilities of students are still low. Cognitive level and problem solving ability are positively correlated