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Pengaruh Ekstrak Etanol pada Tomat (Solanum lycopersicum L.) pada Staphylococcus epidermidis secara in Vitro Pauzan Pauzan; Musparlin Halid; Wulan Ratia Ratulangi
Jurnal Ilmiah Kesehatan Sandi Husada Vol 12 No 1 (2023): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v12i1.1022

Abstract

Tomato is one of the plants that contain lycopene as an antibacterial. Acne is an infectious disease caused by Staphylococcus epidermidis. Antibiotic treatment starts to become resistant so that plants can be used as alternative treatments. The study aimed to determine the effectiveness of the ethanolic extract of tomato (Solanum lycopersicum L) against the growth of Staphylococcus epidermidis bacteria in vitro. This type of research is experimental. Extraction was carried out by maceration method with 96% ethanol as solvent. Lycopene extract with concentrations of 20%, 40%, 60%, 80%, and 100%. Testing with the paper disk method with five repetitions. Aquadest as a negative control, and tetracycline as a positive control. The results showed that the diameter of the inhibition zone formed in the positive control was 40.36 mm (potent inhibition). Inhibition zones at concentrations of 100%, 80%, 60%, 40%, and 20% had solid inhibitory power. The results of statistical tests showed that the ethanolic extract of tomato (Solanum lycopersycom L) had antibacterial effectiveness against the growth of Staphylococcus epidermidis bacteria that causes acne in vitro. The post hoc test shows a significant effect between a T1 concentration of 100% with negative control and positive control
Aktivitas Imunologis Ekstrak Daun Singkong terhadap Peningkatan Monosit pada Mencit dengan Induksi Padi Pauzan Pauzan; Idham Halid
Lambda: Jurnal Ilmiah Pendidikan MIPA dan Aplikasinya Vol. 5 No. 3 (2025): Lambda
Publisher : Lembaga Bale Literasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58218/lambda.v5i3.1579

Abstract

Penelitian ini bertujuan untuk mengevaluasi efek imunomodulator dari ekstrak daun singkong terhadap peningkatan jumlah monosit pada mencit yang diinduksi dengan padi. Dalam penelitian ini, kami menggunakan dua kelompok mencit: kelompok kontrol negatif dan kelompok perlakuan (P). Kelompok kontrol tidak menerima ekstrak daun singkong, sedangkan kelompok perlakuan menerima ekstrak daun singkong dengan dosis tertentu. Jumlah monosit diukur pada kedua kelompok setelah periode perlakuan. Hasil penelitian menunjukkan bahwa ekstrak daun singkong secara signifikan meningkatkan jumlah monosit pada kelompok perlakuan dibandingkan dengan kelompok kontrol. Temuan ini menunjukkan bahwa ekstrak daun singkong memiliki potensi sebagai imunomodulator dengan meningkatkan aktivitas sistem kekebalan tubuh melalui peningkatan jumlah monosit.