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Study of Creatinin Levels of Patients Receiving Antipsycotic Treatment at Mutiara Sukma Psychiatric Hospital, Nusa Tenggara Barat: Studi Kadar Kreatinin Pasien Jiwa yang Menerima Pengobatan Antipsikotik di Rumah Sakit Jiwa Mutiara Sukma, Nusa Tenggara Barat Sukmana, Dhika Juliana; Mentari, Ika Nurfajri; Anjelin, Desak Putu
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 4 No. 2 (2021): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v4i2.1616

Abstract

Mental disorders are clinical and social problems that must be addressed immediately. Long-term use of the drug can cause damage to kidney function and worsen the work of the kidneys. Creatinine is a waste product of creatine phosphate metabolism that occurs in the muscles and is then released into the blood circulation, then transported to the kidneys. The purpose of this study was to determine how the creatinine levels of mental patients receiving antipsychotic treatment at Rumah Sakit Jiwa Mutiara Sukma Hospital, Nusa Tenggara Barat Province. The research method used is qualitative. The type of research used is descriptive, namely looking at data from the Clinical Pathology laboratory installation and medical records to determine the results of examination of creatinine levels in patients with mental disorders. The results showed that from data in the Clinical Pathology laboratory and medical records at Rumah Sakit Jiwa Mutiara Sukma, NTB Province from June-December 2020 with a total of 40 data, there were 30 patients (75%) who had normal creatinine levels, 2 patients (5%) had normal creatinine levels. creatinine levels were low, and 8 patients (20%) had high creatinine levels.
Pengaruh Lama Penyimpanan terhadap Kadar “Gula Reduksi” Nira Aren dengan Penambahan Kapur Sirih Sukmana, Dhika Juliana; Suhada, Adriyan; Yanti, I Gusti Ayu Nyoman Danu; Anam, Haerul
Journal of Authentic Research Vol. 1 No. 1 (2022): January
Publisher : LITPAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/jar.v1i1.636

Abstract

Nira aren mudah mengalami fermentasi yang disebabkan oleh aktivitas mikroba. Untuk mencegah kerusakan nira akibat fermentasi, dibutuhkan pengawetan menggunakan bahan pengawet dengan waktu yang tepat. Penelitian ini bertujuan untuk mengetahui pengaruh variasi waktu penyimpanan terhadap kadar gula reduksi nira aren yang telah ditambahkan kapur sirih. Penelitian ini bersifat true ekperimental yang dilakukan di Laboratorium Kimia Jurusan Analis Kesehatan Poltekkes Kemenkes Mataram untuk mengetahui pengaruh yang timbul akibat dari perlakuan yang diberikan. Perlakuan terdiri atas 4 waktu penyimpanan yaitu 0 jam, 2 jam, 4 jam dan 6 jam dengan masing-masing 6 kali replikasi. Hasil penetapan kadar gula reduksi nira aren masin-masing perlakuan secara berurutan adalah 2,01%, 2,03%, 2,33% dan 0,62%. Kesimpulan dari penelitian ini yaitu waktu simpan maksimal nira aren yang diawetkan dengan kapur sirih adalah 4 jam, sedangkan waktu optimalnya adalah 2 jam. Rekomendasi untuk penelitian lanjutan diuraikan lebih detail dalam artikel ini. The Effect of Storage Duration on the Reducing Sugar Content of Arenga Sap with the Addition of Betel Lime Abstract Aren sap is prone to fermentation caused by microbial activity. To prevent sap damage due to fermentation, preservation using appropriate preservatives is required. This study aims to determine the influence of storage time variations on the reducing sugar content of arenga sap added with betel lime. The study follows a true experimental design conducted at the Chemistry Laboratory, Department of Health Analysts, Polytechnic of Health Ministry of Health Mataram, to assess the effects of the treatments. The treatments consisted of four storage times, namely 0 hours, 2 hours, 4 hours, and 6 hours, each with six replications. The results of reducing sugar content determination for each treatment were 2.01%, 2.03%, 2.33%, and 0.62%, respectively. The conclusion of this research is that the maximum storage time for preserved arenga sap with betel lime is 4 hours, while the optimal time is 2 hours. Detailed recommendations for further research are presented in this article.
Gambaran Profil Lipid pada Peminum Kopi di Dusun Sembung Daye Kecamatan Narmada, Lombok Barat Sukmana, Dhika Juliana; Suhada, Adriyan; Noortiningsih, Noortiningsih; Camin, Yeremiah Rubin; Pauzan, Pauzan; Suhaela, Nursani
Journal of Authentic Research Vol. 1 No. 2 (2022): July
Publisher : LITPAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/jar.v1i2.825

Abstract

Kebiasaan merokok, mengonsumsi alkohol dan kafein membawa dampak yang tidak baik bagi kesehatan. Nikotin yang terkandung dalam rokok dapat meningkatkan sekresi dari katakolamin sehingga meningkatkan lipolisis. Kafein tidak langsung meningkatkan metabolisme energi dalam tubuh.  Konsumsi jangka panjang akan menekan metabolisme energi yang dapat menyebabkan kelelahan adrenal dan berpengaruh buruk pada keseimbangan profil lipid. Penelitian ini dilakukan untuk mengetahui gambaran profil lipid peminum kopi di Dusun Sembung Daye. Penelitian ini merupakan penelitian dengan desain cross sectional dan melibatkan 60 orang responden dengan kriteria peminum kopi, pekerjaan yang seragam dan usia produktif. Sampel darah yang diperoleh kemudian diperiksa di Laboratorium RSUD Patut Patuh Patju, sedangkan data kelompok kontrol diperoleh dari hasil pemeriksaan Laboratorium Klinik Vi Diagnostic Mataram. Intrumen yang digunakan untuk mendapat data sekunder berupa kuisioner kemudian bersamaan dengan data profil lipid dianalisis secara statistic menggunakan SPSS (uji t dan chi kuadrat). Dari penelitian ini diperoleh kadar kolesterol total, trigliserida, High Density Lipoprotein dan Low Density Lipoprotein peminum kopi secara berturut-turut adalah 183,67 mg/dL, 174,75mg/dL, 47,943 mg/dL dan 107,50 mg/dL. Sedangkan untuk kelompok kontrol 174,80 mg/dL, 118,20 mg/dL, 40,075 mg/dL dan 114,68 mg/dL. Hasil analisis statistik menggunakan uji t dan chi kuadrat menunjukkan adanya perbedaan kadar trigliserida dan HDL pada kelompok peminum kopi dengan kelompok kontrol, dimana kadar trigliserida dan HDL kelompok peminum kopi lebih tinggi.  Kadar kolesterol total dan LDL kedua kelompok tidak berbeda. Kafestol dan kafein yang terdapat pada kopi meningkatkan trigliserida dan cenderung tidak memengaruhi kolesterol total dan LDL, sedangkan asam klorogenat pada kopi memiliki efek sebagai antioksidan yang meningkatkan kadar HDL. Profil Lipid on Coffee Drinker in Sembung Daye Village  Subdistrict of Narmada, West Lombok Abstract The habit of smoking and consuming alcohol and caffeine has an impact that is not good for health. The nicotine in cigarettes can increase the secretion of catecholamines, thereby increasing lipolysis. Caffeine does not directly increase energy metabolism in the body. Long-term consumption will suppress energy metabolism, which can cause adrenal fatigue and adversely affect the balance of lipid profiles. This study described the lipid profile of coffee drinkers in Sembung Daye Hamlet. The research used a crcross-sectional design and involved 60 respondents with the criteria of coffee drinkers, uniform work and productive age. The blood samples obtained were then examined at the Patut Patuh Patju Hospital Laboratory. At the same time, the control group data were obtained from the results of the Vi Diagnostic Mataram Clinic Laboratory. The instrument used to obtain secondary data in the form of a questionnaire and then the lipid profile data were analyzed statistically using SPSS (t test and chi-square). From this study, the total cholesterol, triglyceride, High-Density Lipoprotein, and Low-Density Lipoprotein levels of coffee drinkers were 183.67 mg/dL, 174.75mg/dL, 47.943 mg/dL and 107.50 mg/dL, respectively. While for the control group 174.80 mg/dL, 118.20 mg/dL, 40.075 mg/dL and 114.68 mg/dL. The results of statistical analysis using t and chi-square tests showed differences in triglyceride and HDL levels in the coffee drinker group and the control group, where triglyceride and HDL levels in the coffee drinker group were higher. Total and LDL cholesterol levels were not different between the two groups. The caffeine and caffeine found in coffee increase triglycerides and tend not to affect total and LDL cholesterol, while the chlorogenic acid in coffee has an antioxidant effect that increases HDL levels.
Hubungan Profil Darah Lengkap dengan Hasil Tes Cepat Molekuler (TCM) Pasien Terduga Tuberculosis Anisyah, Anisyah; Pauzan, Pauzan; Sukmana, Dhika Juliana
JSN : Jurnal Sains Natural Vol. 2 No. 4 (2024): November
Publisher : Puslitbang Sekawan Institute Nusa Tenggara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35746/jsn.v2i4.626

Abstract

Tuberculosis is a contagious infectious disease caused by mycobacterium tuberculosis which generally attacks the lungs in humans. This disease is transmitted by positive BTA sufferers and spreads through droplet nuclei when the sufferer coughs or sneezes. Bacteria that spread in the air can be transmitted by healthy people and can cause infection. The aim of this study was to determine the relationship between complete blood profiles and the results of rapid molecular test in patients suspected of having tuberculosis. This type of research uses analytical observational with a cross- sectional design. This study used secondary data from medical records of tuberculosis patients at the NTB Provincial Regional Hospitals. The collected data from complete blood examination results and molecular rapid tests are processed and presented in tabular form. The processed data was then analyzed statistically using SPSS with the chi-square test. Based on the results of research regarding the relationship between complete blood profiles and the results of the rapid molecular test for suspected tuberculosis patients at the NTB Provincial Regional Hospital, when examining leukocytes, erythrocytes, and platelets the p-value or sig. was obtained > 0,05, namely there is no significant relationship between the two variabels. Meanwhile, for hemoglobin, the P-Value was < 0,05, namely that there was a significant relationship between the two variabels
Edukasi Perilaku Hidup Bersih dan Sehat dalam Pencegahan Komplikasi Luka Diabetes Mellitus di Dusun Panggungan Trihanggo Gamping Sleman Noamperani, Sapta Rahayu; Sukmana, Dhika Juliana; Anggraeni, Fitri Putri; Rini, Sulis Tia; Milataki, Khirniq Qiqi; Apriliani, Elfrida
Bakti Sekawan : Jurnal Pengabdian Masyarakat Vol. 5 No. 2 (2025): Desember
Publisher : Puslitbang Sekawan Institute Nusa Tenggara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35746/bakwan.v5i2.768

Abstract

Background: Diabetes mellitus (DM) is one of the main challenges in global health with a high incidence rate, including in Indonesia. In Yogyakarta, the diabetes prevalence rate reaches 3,6%, with a significant number of patients experiencing serious complications such as diabetic wounds that can lead to amputations. Purpose: This study aims to expand the public’s knowledge and awareness of clean and healthy living behaviors (PHBS) as an effort to prevent wound complications in diabetes mellitus patients. The community service activity was conducted in Dusun Panggunan Trihanggo, Gamping, involving 25 elderly participants. Methods: The method applied includes outreach in the form of lectures and interactive discussions through question and answer sessions, supplemented by pre-test and post-test to assess the improvement in participants knowledge, with a p-value of 0,03 (p <0,05). The participants enthusiasm was reflected in the numerous questions asked during the Q&A sessions. Conclusion :  Education about PHBS has a significancy positive impact on the community of diabetes mellitus patients, enhancing their understanding of the importance of maintaining cleanliness to prevent wound complications. This activity demonstrates that health education is effective in raising awareness and knowledge among the community regarding the health issues they face.
Perbedaan Nilai LED (Laju Endap Darah) Menggunakan Larutan Natrium Sitrat 3,8% Dengan Dextrosa 5% Hasanah, Nurul Hikmatil; Sukmana, Dhika Juliana; Sundayani, Lina; Diarti, Maruni Wiwin
JSN : Jurnal Sains Natural Vol. 1 No. 1 (2023): Februari
Publisher : Puslitbang Sekawan Institute Nusa Tenggara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (294.763 KB) | DOI: 10.35746/jsn.v1i1.288

Abstract

Pemeriksaan LED (Laju Endap Darah) adalah pemeriksaan yang dilakukan untuk melihat kecepatan darah dalam membentuk endapan yang diukur selama 1 jam yang di dalam pemeriksaannya diperlukan larutan pengencer. Larutan pengencer yang biasanya digunakan adalah larutan Natrium sitrat3,8%, namun di lapangan sering juga digunakan larutan Dextrosa 5%. Tujuan dari penelitian ini adalah untuk mengetahui adanya perbedaan nilai LED menggunakan larutan Natrium sitrat 3,8% dengan Dextrosa 5%. Penelitian ini dilakukan di Laboratorium Patologi Klinik Analis Kesehatan Poltekkes Kemenkes Mataram. Penelitian ini merupakan penelitian Observasional analitik. Sampel yang digunakan adalah darah responden yang memenuhi kriteria inklusi dan eksklusi. Darah diambil sebanyak 3 ml kemudian dilakukan pemeriksaan nilai LED menggunakan Natrium sitrat 3,8% dan Dextrosa 5%. Data yang diperoleh kemudian dianalisis dengan uji statistik Mann-Whitney. Hasil uji statistik dengan Mann-Whitney menunjukkan tidak terdapat perbedaan yang signifikan antara nilai LED menggunakan Natrium sitrat 3,8% dengan Dextrosa 5%, dimana didapatkan nilai P 0,219 > ? 0,05. Larutan Dextrosa 5% dapat digunakan sebagai alternatif lain larutan pengencer dalam pemeriksaan nilai LED.
Literature Review: Hubungan dan Peranan Interleukin-6 (Il-6) pada Penderita COVID-19 Cindrayani, Sulis; Sukmana, Dhika Juliana; Hadiatun, Nurul; Aini, Aini
JSN : Jurnal Sains Natural Vol. 1 No. 3 (2023): Agustus
Publisher : Puslitbang Sekawan Institute Nusa Tenggara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35746/jsn.v1i3.391

Abstract

Coronavirus disease 2019 or better known as COVID-19 is an acute respiratory disease caused by Savere Acute Respiratory Syndrome-2 (SARS CoV-2). The purpose of this study was to determine the role and relationship of interleukin-6 (IL-6) in patients with COVID-19. The research method is a Systematic Literature Review (SLR) using electronic articles in English and Indonesian, the year the article was published starting from 2019 with a secondary research design with supporting data with the theme of the study taken, namely with the keywords: COVID-19, interleukin-6, cytokine storm in COVID-19 sufferers. In searching articles with the help of several databases. On average, the results of the 8 research articles used in this literature review show that there is a relationship and role for interleukin-6 (IL-6) in people with COVID-19. In conclusion, IL-6 has a role and relationship to sufferers of COVID-19
Pengaruh Penambahan Glukosa terhadap Pertumbuhan Bakteri Escherichia coli pada Media Pemupuk Nutrient Broth (NB) Hidayati, Nurul; Sukmana, Dhika Juliana; Ariami, Pancawati; Urip, Urip; Fihiruddin, Fihiruddin
JSN : Jurnal Sains Natural Vol. 2 No. 2 (2024): Mei
Publisher : Puslitbang Sekawan Institute Nusa Tenggara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35746/jsn.v2i2.538

Abstract

Infectious diseases are caused by microorganisms, one of them is Escherichia coli. The process of isolation and identification of bacteria requires enrichment media to increase the number of bacteria. Media Brain Infusion Broth (BHIB) media, the growth of Escherichia coli bacteria is better than Nutrient Broth (NB). Demahui's glucose as a normal source of organic carbon for the growth of Escherichia coli bacteria, while in NB media there is no glucose. This study is quoted to obey the effect of the addition of glucose on the NB fertilizer media on the growth of Escherichia coli bacteria. This study is a pre-ecperimental study of the addition of 1 gram of glucose, 2 grams, 3 grams, 4 grams and 5 grams of media Nutrient Broth fertilizer media (NB). Termanhan is observed from the number of colonies that grow on the nutrient media so that the plate (NAP). The sample used was the suspension of the pure isolates of the Escherichia coli ATCC 35218. The calculation of the average number of colonies obtained from each treatment was 79, 90, 144, 126, and 103 colonies with a control of 63 colonies. Based on the statistical test one -way ANOVA P value (0,000) <? (0.05) which means there is an influence of the addition of glucose on the growth of Escherichia coli bacteria Nutrient Broth (NB). The optimal concentration of the addition of glucose is 3 grams in 1 L of NB media.
PREVALENSI HBsAg POSITIF PADA PENDONOR DARAH DI UNIT DAERAH PALANG MERAH INDONESIA LOMBOK BARAT Kisniarti, Linda; Sukmana, Dhika Juliana; Aini, Aini; Alfisahrin, Alfisahrin; Halid, Idham
JSN : Jurnal Sains Natural Vol. 1 No. 2 (2023): May
Publisher : Puslitbang Sekawan Institute Nusa Tenggara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (326.404 KB) | DOI: 10.35746/jsn.v1i2.347

Abstract

Hepatitis B virus infection is the main cause of acute and chronic hepatitis, cirrhosis and liver cancer, 25% of whom experience jaundice. Blood transfusion is one of the most common routes of HBV transmission. The purpose of this study was to determine the prevalence of reactive and non-reactive HBsAg in the West Lombok Indonesian Red Cross unit. This type of research is descriptive, carried out in June 2022 at the West Lombok Indonesian Red Cross Unit. The results showed that the largest number of donors were men (12,201 people) and the age group of 25-44 years (4,342 people). Based on the results of the HBsAg examination, the prevalence of positive HBsAg in men was 76% and 24% in women.
Noni (Morinda Citrifolia) Ethanol Extract Lowered Blood Glucose Levels, Increased Glutathione Peroxidase Activity, And Decreased Malondialdehyde in White Rats Model of Diabetes Arjita, I Putu Dedy; Saputra, I Putu Bayu Agus; Sukmana, Dhika Juliana
Jurnal Penelitian Pendidikan IPA Vol 9 No 12 (2023): December
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i12.6076

Abstract

Diabetes mellitus can increase oxidative stress and damage cells. Noni fruit has antibacterial, antifungal, antitumor, analgesic, hypotensive, and anti-inflammatory benefits, can boost immunity, and has antioxidant content. Noni contains phenolic compounds (anthraquinones, acuities, asperulosides, and scopoletin), organic acids (capric and caprylic acids), and alkaloids (xeronine). The effect of noni ethanol extract can significantly reduce blood glucose (P<0.05) of the T2 group (177.00±137.78) and T3 (159.40±86.53) when compared to the C+ group (511.00±131.45). The T1 group (387.40±170.06) had no significant difference (P>0.05) when compared to the C+ group (511.00±131.45), but there was a decrease in the average yield at T1 (387.40±170.06). Serum malondialdehyde (MDA) examination showed a significant decrease (p<0.05) in T1 (1188.32±93.41), while in T2 (1385.35±38.65) and T3 (1460.32±42.51) was not significant (p<0.05). Examination of serum glutathione peroxidase (GPX) showed a significant decrease in T1 (119.97±37.45), there was a decrease in GPX levels, while in the T2 group (236.14±6.05) and T3 (185.24±43.07), there was no decrease. Noni ethanol extract can lower blood glucose levels, reduce Malondialdehyde levels, and prevent increased activity of the enzyme glutathione peroxidase. Flavonoid compounds in noni ethanol extract can avoid increased blood glucose and reduce free radicals formed due to hyperglycemia conditions. Â