Claim Missing Document
Check
Articles

Found 12 Documents
Search

Pengembangan Produk dan Uji Hedonik Madu Hutan dari Apis sp. Dengan Penambahan Ekstrak Strawberry dan Melati Soegiantoro, Didiek Hardiyanto; Widhiarso, Ari; Damayanti, Sindi; Maharani, Cintia; Prameswari, Laura Dyah; Tudang, Cesy; Abigael, Eltri
Jurnal Kesehatan Ilmiah Aufa Royhan Vol 9 No 2 (2024): Vol. 9 No. 2 Desember 2024
Publisher : Universitas Aufa Royhan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51933/health.v9i2.1762

Abstract

The use of honey as a traditional medicine has been known by the community. Forest honey is considered better and more efficacious than cultivated honey because it has a higher content of efficacious compounds with a lower water content. The development of forest honey products with the addition of natural ingredient extracts is considered to be able to increase market potential because it increases health benefits. The problem studied is the market response to forest honey products with the addition of natural ingredient extracts using hedonic test parameters. The aim is to see the market potential for the acceptance of this product. The method used for forest honey production through the honey processing stage to minimize the enzymatic process, the addition of natural ingredient extracts, packaging with primary single-drinking sachet packaging and secondary packaging, and marketing. The results of the study showed that the hedonic test of forest honey products with the addition of natural ingredient extracts received a very good response, where most respondents stated that their responses were really liked and liked. The strawberry extract variant is preferred over jasmine extract, while the packaging can still be improved to attract more consumers. Marketing strategies need to be developed more variedly by utilizing the existing marketing mix. The conclusion is that forest honey products with the addition of natural ingredient extracts packaged in single-drinking sachet packaging have great potential to be developed with several modifications to the packaging and marketing strategies.
KRT23 SEBAGAI BIOMARKER PROGNOSTIK PADA ADENOKARSINOMA REKTAL: ANALISIS BIOINFORMATIKA BERBASIS UALCAN: KRT23 sebagai Biomarker Prognostik pada Adenokarsinoma Rektal: Analisis Bioinformatika Berbasis UALCAN Danang Prasetyaning Amukti; Mitha Dwi Puspitasari; Ari Widhiarso; Bayu Bakti Angga Santoso; Ria Indah Pratami
Jurnal Ilmiah JOPHUS : Journal Of Pharmacy UMUS Vol. 7 No. 2 (2026): Februari
Publisher : Program Studi Farmasi, Universitas Muhadi Setiabudi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46772/jophus.v7i2.1836

Abstract

 Introduction: Colorectal cancer, including READ, is one of the leading causes of cancer death worldwide. Recent studies have shown the involvement of the KRT23 gene, a member of the type I keratin family, in various malignant processes, including tumor cell proliferation, migration, and invasion. Although KRT23 expression has been studied in several types of cancer, its role in rectal cancer remains poorly understood. This study aimed to evaluate the relationship between KRT23 expression and patients' clinical characteristics and their survival. Methods: KRT23 expression data in rectal cancer patients were obtained from the UALCAN platform, which included subgroups based on race, sex, and weight status. Analysis was performed to evaluate the relationship between KRT23 expression levels and patients' clinical characteristics and their effects on survival using Kaplan-Meier curves and log-rank statistical analysis. Results: KRT23 expression was significantly increased in rectal cancer tissues compared to normal tissues. Survival analysis showed that race significantly affected the relationship between KRT23 expression and patient prognosis (p < 0.0001), especially in the Caucasian and African-American racial groups. In contrast, there was no significant difference based on gender (p = 0.97) and weight status (p = 0.64). Conclusion: High KRT23 expression is associated with better prognosis in certain racial subgroups, making it a potential candidate prognostic biomarker for rectal cancer. However, further studies with larger sample sizes are needed to strengthen these findings and understand the underlying biological mechanisms.