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All Journal JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA MATRIK : Jurnal Manajemen, Teknik Informatika, dan Rekayasa Komputer Jurnal Ners Acta Chimica Asiana Jurnal Pijar MIPA Jurnal Ilmiah Pengabdian dan Inovasi Jurnal Pengabdian kepada Masyarakat IPTEKS
Sri Winarni Sofya
Universitas Bumigora
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Physics Social Sciences Other

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Aktivitas Antimikroba Ekstrak Etanol Daun Sirsak (Annona muricata L) Terhadap Bakteri Gram Negatif Eschericia coli I Nyoman Bagus Aji Kresnapati; Sri Winarni Sofya
Jurnal Ners Vol. 7 No. 1 (2023): APRIL 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v7i1.12996

Abstract

Sirsak (Annona muricata L) merupakan salah satu tanaman herbal yang bermanfaat bagi kesehatan, diantaranya dimanfaatkan sebagai antimikroba. Penelitian ini bertujuan menguji kandungan senyawa fenolik yang  memiliki aktivitas antimikroba bakteri gram negatif Eschericia coli. Daun-daun yang telah dikeringkan di ekstraksi maserasi dengan dilarutkan dengan pelarut etanol 96% selama 3x24 jam. Hasil maserat pertama dan  kedua di pekatkan dengan rotary evaporator. Hasil ekstrak di tes fitokimia untuk mengetahui kandungan senyawa fenolik pada daun sirsak. Uji aktivitas antimikroba dilakukan dengan metode difusi sumuran  sebanyak 4 lubang pada media yang telah di inokulasi bakteri gram negatif Eschericia coli yang masing-masing lubang terdiri lubang A disuspensi etanol 96%, lubang B antibiotik standar 0,5 %, lubang C ekstrak etanol daun sirsak (EtDS 0,5%) dan lubang D EtDS 1%. Hasil penelitian berupa daerah jernih disekitar sumuran yang diameternya di ukur dengan penggaris. Hasil penelitian berupa rerata diameter antara kelompok A, B, C, dan D yang kemudian di bandingkan zona yang lebih luas dan kekuatan aktivias zona hambatnya. Hasil penelitian menunjukkan diantara 4 kelompok perlakuan, lubang sumuran yang di suspensi antibiotik 0,5% (A) memiliki diameter zoba hambat lebih luas dengan diameter 19,5 mm, kemudian EtDS 1% (D) 11,35 mm, EtDS 0,5% (C) 6,49 dan Et (A) 1,25 mm. Hasil penelitian menunjukkan aktivitas ekstrak etanol daun sirsak 1% (D) berpotensi sebagai antimikroba bakteri gram negatif Eschericia coli, namun tidak lebih efektif dibandingkan antibiotik standar 0,5%.
Physical test and irritation test of water guava leaf extract (Syzygium aqueum) as a natural spray hand sanitizer Sofya, Sri Winarni; Muhsin, Lalu Busyairi
Acta Chimica Asiana Vol. 7 No. 2 (2024)
Publisher : The Indonesian Chemical Society, Chapter Nusa Tenggara and The University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/aca.v7i2.212

Abstract

This study explores the manufacture of water guava (Syzygium aqueum) leaf extract-based hand sanitizers as an effective and safe natural alternative for maintaining hand hygiene. Given the importance of hand hygiene in preventing the spread of disease, especially amid the COVID-19 pandemic, the use of hand sanitizers has increased significantly. However, alcohol-based products are often irritating to the skin. Therefore, this study aims to evaluate the potential of water guava leaf extract to improve the effectiveness and convenience of hand sanitizers. Water guava leaves contain active compounds such as flavonoids, tannins, and phenolics with antibacterial and anti-inflammatory properties. The research method includes extracting water guava leaves, hand sanitizer formulation, and organoleptic, pH, homogeneity, and irritation testing. The tests carried out were physical tests, including organoleptic tests (shape, smell, and colour), pH, homogeneity, spreadability, adhesiveness, and product irritation tests. The research was designed with a posttest-only control group design with true experimental by analyzing the test object after being given treatment. This research is expected to produce products that are useful for the community. The results showed that all hand sanitizer formulas tested had a pH within the safe range of pH 5 for the skin without irritating the skin of the test animals. Formulas with added guava extract showed improved aroma and anti-irritation, with formulas F1 and F2 gaining the highest preference in aroma and colour. This study concludes that water guava leaf extract can be effectively used in the manufacture of hand sanitizers, providing a gentler and skin-friendly alternative to alcohol-based synthetic products.
Penyuluhan Pentingnya Cuci Tangan Yang Baik dan Benar Dalam Upaya Pencegahan Infeksi Cacing di SDN 15 Cakranegara Mia Ariasti; Lalu Busyairi Muhsin; Salsabila Yunita Kurniawan; Sri Winarni Sofya; Ayudia Cipta khaerani; Novitarini
Jurnal Pengabdian kepada Masyarakat IPTEKS Vol. 2 No. 1 (2024)
Publisher : Rajawali Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Abstract: Worm infestation is a parasitic infection that can affect the health, nutrition, intelligence and productivity of patients, especially in primary school-aged children. The disease often occurs due to unsanitary lifestyles and poor sanitation, with a high prevalence in Indonesia, especially in West Nusa Tenggara Province. Children aged 5-14 years, especially in areas with low economic levels, are particularly vulnerable to worms due to a lack of knowledge about clean and healthy living behaviors (PHBS). One solution that can be implemented is to provide counseling to children on how to wash their hands properly to prevent worm infections. This counseling activity was conducted at SDN 15 Cakranegara using a participatory approach, in collaboration with the school and local community. The results of this activity show that counseling can increase children's understanding of the importance of washing hands with soap and running water, which is expected to prevent the spread of worm infections and other related diseases. The success of this counseling is an important step in efforts to increase health awareness among children and communities.
Combination Forward Chaining and Certainty Factor Methods for Selecting the Best Herbs to Support Independent Health Azwar, Muhamad; Winarni Sofya, Sri; Malika, Riwayati; Hairani, Hairani; Ximenes Guterres, Juvinal
MATRIK : Jurnal Manajemen, Teknik Informatika dan Rekayasa Komputer Vol 24 No 2 (2025)
Publisher : LPPM Universitas Bumigora

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/matrik.v24i2.4485

Abstract

The use of herbal medicine as an alternative treatment is increasingly popular due to its natural benefits and cultural significance. However, a lack of public knowledge about the effectiveness, appropriate dosages, and processing methods of herbal remedies poses a significant barrier to their proper utilization. This knowledge gap often leads to suboptimal or even unsafe usage of herbal medicines. To address this issue, this study proposes an application-based system combining the Forward Chaining and Certainty Factor methods to provide personalized recommendations for the best herbal remedies supporting self-health management. The research aims to enhance accessibility to reliable information on herbal treatments while ensuring accurate and user-specific recommendations. By utilizing the ForwardChaining and Certainty Factor method, this system identifies suitable herbal plants based on the type of disease, processing techniques, recommended dosages, and duration of treatment. Meanwhile, the Certainty Factor method calculates the level of certainty for each recommendation provided. The study’s results showed a validation rate of 90%, indicating that the combination of these two methods effectively bridges the gap between traditional herbal knowledge and modern health needs. This study concludes that the system offers a practical tool for individuals to select and use herbal treatments safely and effectively, promoting better health outcomes.
Analgesic Activity Test Of Leunca Leaves (Solanum nigrum L.) Ethanol Extract With Randall Selitto Method Ariasti, Mia; Sofya, Sri Winarni
Jurnal Pijar Mipa Vol. 20 No. 2 (2025)
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v20i2.8439

Abstract

Abstract: Pain is a sensory and emotional experience related to tissue damage. This study aims to determine the analgesic effect of leunca leaf ethanol extract and determine the dose of leunca leaf ethanol extract that has the highest analgesic activity with the Randall Selitto method. Randall Selitto method has been widely used for the development of non-steroidal anti-inflammatory drugs. Leunca leaf powder was extracted using maceration method with 96% ethanol solvent. A total of 25 wistar male white rats were divided into 5 groups, namely positive control mefenamic acid 9 mg / 200 g BW, negative control CMC Na 1%, ethanol extract of leunca leaves doses of 5 mg / 200 g BW, 10 mg / 200 g BW and 20 mg / 200 g BW. The data obtained were analyzed by ANOVA test, then LSD test was used to determine the differences between groups. The results showed that the extract doses of 5 mg / 200 g BW, 10 mg / 200 g BW, 20 mg / 200 g BW and positive control were significantly different from the negative control group. The extract dose of 20 mg / 200 g BB is comparable to the positive control, indicating that the extract dose of 20 mg / 200 g BB has the highest analgesic activity. Steroid and flavonoid compounds contained in leunca leaves are thought to have an effect as analgesics.
Sosialisasi dan Demonstrasi Pengolahan Sampah Rumah Tangga menjadi Produk Eco-enzyme Yulia Hasni Pratiwi; Sri Winarni Sofya; Lalu Busyairi Muhsin; Muhammad Eka Putra Ramandha; Nyoman Bagus Aji K
Jurnal Ilmiah Pengabdian dan Inovasi Vol. 1 No. 4 (2023): Jurnal Ilmiah Pengabdian dan Inovasi (Juni)
Publisher : Insan Kreasi Media

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57248/jilpi.v1i4.237

Abstract

Garbage is a crucial problem faced by all countries in the world, including Indonesia. The waste generation in the province of NTB in 2021 reached 2,637 tons/day, which comes from 10 districts/cities in NTB. Of this amount, only a small portion, namely around 20%, goes to the Final Disposal Site (TPA) and is recycled, while 80% of the total waste is not managed properly. Therefore, to overcome this problem, we offer an innovative solution to process the waste into "eco-enzyme" products which benefits can be felt by the people of Nyur Lembang Village by made demonstration and Socialization on 4Th June 2023 at the Village meeting hall of Nyur Lembang. The Team makes sure to the Villagers that eco-enzymes are not only a solution to reduce waste around us as a form of caring for the earth, but eco-enzymes are also an environmentally friendly, multifunctional, and very economical solution for Nyur Lembang villagers.
Sosialisasi Pemanfaatan Tanaman sebagai Obat dan Kosmetika Muhsin, Lalu Busyairi; Baiq Yulia Hasni Pratiwi; Sri Winarni Sofya; Muhammad Eka Putra Ramandha; Eka Nurul Qomaliyah; Nyoman Bagus Aji K
Jurnal Ilmiah Pengabdian dan Inovasi Vol. 2 No. 2 (2023): Jurnal Ilmiah Pengabdian dan Inovasi (Desember)
Publisher : Insan Kreasi Media

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57248/jilpi.v2i2.324

Abstract

The utilization of plants as medicine and cosmetics is essentially plants with medicinal properties that are grown on yard land managed by families. These plants are planted in order to fulfill the family's need for traditional medicines that can be made and grown at home. The benefits are to fulfill the need to overcome health problems traditionally (medicine). The crops are planted in order to fulfill the family's need for traditional medicines that can be made and grown at home. The benefits are to fulfill the need to overcome health problems traditionally (medicine). Therefore, it is very important to carry out a planting movement in the surrounding environment not only at home, for example in the school.  In this community service research, one of them aims to carry out a planting and utilization movement in the women's dormitory environment. This can also increase the interaction of students with nature and its utilization can provide a preventive benefit in overcoming health problems in the school environment.  The results of the assistance of community service activities regarding the partnership program on planting and utilization assistance. Medicinal and cosmetic plants at MAN 3 Mataram, showed significant results in several things such as students being able to plant and utilize medicinal and cosmetic plants in the environment.
Antiinflammatory Activity of Bangle Rhizome (Zingiber purpureum Roxb) Ethanol Extract on Rat Carrageenan Induced and Erythema Method Mia Ariasti; Muhammad Eka Putra Ramandha; Sri Winarni Sofya
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 12 No. 1 (2025): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v12i12025.50-58

Abstract

Background: Inflammation is a physiological response triggered by cellular damage, typically characterized by symptoms such as edema. Objective: This study was conducted to evaluate the anti-inflammatory activity of the ethanol extract of Bangle rhizome (Zingiber purpureum Roxb.) using the carrageenan-induced paw edema method and the UVB-induced erythema method. The most effective dose demonstrating significant anti-inflammatory activity was also determined. Methods: The bangle rhizome (Zingiber purpureum Roxb) was subjected to maceration using 96% ethanol. A total of 25 rats were randomly divided into five groups: negative control (0.5% CMC-Na), positive control (diclofenac sodium at 0.9 mg/200 g body weight), and treatment groups receiving ethanol extract of bangle rhizome at doses of 5, 10, and 20 mg/200 g body weight. In the carrageenan-induced method, the edema volume in the rat paw was measured following the administration of 0.8% lambda-carrageenan. In the erythema method, the degree of inflammation was assessed using UVB-induced erythema scoring. Results and Conclusion: Anti-inflammatory activity was observed at doses of 5, 10, and 20 mg/200 g body weight in the carrageenan model and at doses of 10 and 20 mg/200 g in the erythema model. The most potent anti-inflammatory effect was recorded at the dose of 20 mg/200 g body weight, which was comparable to the positive control in both models. The presence of flavonoids and steroids in the extract may contribute to the observed anti-inflammatory activity.
Co-Authors Ayudia Cipta Khairani Baiq Yulia Hasni Pratiwi Eka Nurul Qomaliyah Hairani Hairani Kresnapati, I Nyoman Bagus Aji Malika, Riwayati Mia Ariasti Muhamad Azwar, Muhamad Muhammad Eka Putra Ramandha Muhsin, Lalu Busyairi Novitarini Nyoman Bagus Aji K Salsabila Yunita Kurniawan Ximenes Guterres, Juvinal Yulia Hasni Pratiwi