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All Journal Jurnal Pengabdian Kepada Masyarakat (Indonesian Journal of Community Engagement) Paediatrica Indonesiana Sumatera Medical Journal Indonesian Journal of Global Health research Cermin Dunia Kedokteran Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Ta'diban: Journal of Islamic Education Jurnal Sinergi Mengabdi
Syamsidah Lubis, Syamsidah
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Religion Humanities Decision Sciences, Operations Research & Management Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Indonesian Journal of Global Health research

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The Relationship Between Lipid Profile and the Incidence of Relapsing Nephrotic Syndrome in Children Tarigan, Utari Olivina; Siregar, Rosmayanti Syafriani; Lubis, Syamsidah; Fujiati, Isti Ilmiati; Deliana, Melda; Prima, Cynthea
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.7017

Abstract

Nephrotic syndrome (NS) is one of the most common chronic kidney diseases in children, characterized by massive proteinuria, hypoalbuminemia, edema, and dyslipidemia. Relapse occurs in most cases and contributes to worsening the disease course. Dyslipidemia is suspected to influence relapse risk, but the specific relationship between lipid profile and relapsing NS remains unclear. Objective to analyze the association between total cholesterol, triglycerides, LDL, and HDL levels with relapse incidence in children with nephrotic syndrome. A retrospective study was conducted on 66 children aged 2–18 years with NS treated at H. Adam Malik General Hospital, Medan, in 2024. Subjects were divided into relapsing (n=54) and non-relapsing (n=12) groups. Data were obtained from medical records and analyzed using the Mann-Whitney test and Spearman correlation. Triglyceride (p=0.007), LDL (p=0.013), and HDL (p<0.001) levels differed significantly between the relapsing and non-relapsing groups. Total cholesterol showed no significant difference (p=0.164). The mean albumin level was significantly lower in the relapsing group (2.9 g/dL vs. 4.1 g/dL; p<0.001). A significant negative correlation was found between albumin and triglyceride levels (r=-0.326; p=0.008). Triglyceride, LDL, and HDL levels are significantly associated with relapse in pediatric nephrotic syndrome. Hypoalbuminemia is also an important risk factor. Lipid profile evaluation can serve as a useful indicator in monitoring and managing relapses.
The Impact of Age on Seizure Severity Characteristics in Children With Drug Resistant Epilepsy Lestari, Tria Diana; Tanjung, Ika Citra Dewi; Lubis, Syamsidah; Harahap, Juliandi; Saing, Johannes Harlan; Dalimunthe, Wisman
Indonesian Journal of Global Health Research Vol 7 No 3 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i3.5890

Abstract

Drug-resistant epilepsy (DRE) is found in up to one-third of individuals with epilepsy who have received appropriate therapy and this condition causes significant child morbidity and mortality. Epilepsy that appears at an early age is at higher risk of developing DRE. Objective to assess the effect of age on the characteristics of seizure severity in children with DRE. This study used a cross-sectional design involving 36 DRE patients aged 2-18 years at the Child Neurology Polyclinic, Adam Malik Hospital Medan, from September to October 2024. Seizure severity characteristics were assessed using the Global Assessment of the Severity of Epilepsy (GASE) questionnaire instrument. The categorical data are presented in the form of proportions and the effect of age on seizure severity characteristics was analyzed using the chi-square test. There were 36 children with DRE in this study, predominantly aged ≥ 10 years. Bivariate analysis showed a significant effect of age in children with drug resistant epilepsy only on the disruption of activity experienced by children with a p value = 0.036 (p <0.05). Most patients aged ≥ 10 years did not experience activity disorders or experienced mild activity disorders (73.9%), while in patients aged <10 years, most patients experienced severe activity disorders (61.5%). The age of children with drug resistant epilepsy have a significant effect on daily activity disorders.
Co-Authors Beby Syofiani, Beby Bugis Mardina Lubis, Bugis Mardina Dasa Tjipta, Guslihan Dimyati, Yazid Dinda Sani Pratiwi Dwi Faradina Febriyanti Marito Lubis, Nikmah Fujiati, Isti Ilmiati Guslihan Dasa Tjipta, Guslihan Dasa Harahap, Juliandi Husada, Muhammad Surya Indriyani, Anggie Khairul Khairul, Khairul Lestari, Tria Diana Mardina Lubis, Bugis Melda Deliana, Melda Mohammad Ramli Muthma'innah, M Nasution, Bayu Rusfandi Nurul Izza Nadeak Pertin Sianturi Pitriyani Prima, Cynthea Putri, Della Surya Putri, Ruth Angelia Rahmadani, Alvia Rina Amelia Risma Kerina Kaban, Risma Kerina Rismala Dewi Saing, Johannes Harlan Sari Mahwati Hasibuan Siregar, Rosmayanti Syafriani Sitanggang, Fitri Parinda Solly Aryza Sovinah, Nurul Syofiani Hasibuan, Beby Tanjung, Ika Citra Dewi Tarigan, Utari Olivina Triyanthi Lubis, Arvitamuriany Wahyuni, Fera Wisman Dalimunthe, Wisman Zakky Abdillah, Hafaz