Kurnia Wahyudi
Departemen Ilmu Kesehatan Masyarakat, Fakultas Kedokteran Universitas Padjadjaran

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Tacrolimus Therapy Among Steroid-Resistant Nephrotic Syndrome Children: A Preliminary Study in West Java, Indonesia Widiasta, Ahmedz; Wahyudi, Kurnia; Rachmadi, Dedi
International Journal of Integrated Health Sciences Vol 12, No 2 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n2.3663

Abstract

Objective: To explore the outcomes of Tac therapy for Steroid-Resistant Nephrotic Syndrome (SRNS) and its implication in reducing the number of CKD events.Methods: An open, prospective, cohort study was conducted at a tertiary hospital in Bandung, West Java, Indonesia. Children (age 1–18 years old) with steroid and cyclophosphamide resistant nephrotic syndrome were enrolled in this study. Blood pressure, urinary protein, serum ureum, and creatinine levels were measured every month, Tac and soluble urokinase plasminogen activator receptor (supaR) levels were assessed at the 0, third, and sixth months.Results: Ten of fifteen subjects enrolled in this study got better within 3–6 months with a trend of decreasing suPAR level and proteinuria, as well as stable blood pressure and serum creatinine and ureum level. During treatment, no side effects of the subjects were found with the Tac level maintain safely.Conclusion: Tac is an effective and safe agent in treating SRNS, especially for those do not respond well to an alkylating agent.
GAMBARAN TINGKAT KEPATUHAN MINUM OBAT ANTIHIPERTENSI DI PUSKESMAS JATINANGOR Tsara Syarifah Istiqomah; Julia Ramadhanti; Kurnia Wahyudi
JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol 7 No 1 (2019): JIMKI : Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Volume 7.1 Edisi Januari - A
Publisher : BAPIN-ISMKI (Badan Analisis Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53366/jimki.v7i1.396

Abstract

Hypertension is the most common cardiovascular disease. This non-communicable disease cannot be cured but can be controlled by taking antihypertensive drugs regularly. Patient’s low compliance can be one of the factors that aggravates the patient's condition. This study aims to describe the proportion of patient’s adherence for taking antihypertensive drugs in Puskesmas Jatinangor using the Eight-Items Morisky Medication Adherence Scale (MMAS-8) questionnaire. This study was hold between September 2017 and August 2018 and was described using descriptive analytical method with crosssectional study design. From 74 respondents who participated in this study, we obtained the data in the form of sex, age, education level, marital status, occupation, income, payment media, hypertension duration, number of drugs consumed, type of medication, and motivational support. The data showed that 74 hypertensive patients in Puskesmas Jatinangor have a high compliance on taking antihypertensive drugs. We expect the results of this study can increase public awareness about drug compliance, especially for antihypertensive drugs in the working region of Puskesmas Jatinangor.
The Influence of COVID-19 Severity on Maternal and Perinatal Outcomes: Evidence from a Cohort Study in Indonesia Aziz, Muhammad Alamsyah; Nurdiawan, Windi; Avivi, Safiya Fathina; Wahyudi, Kurnia; Irianti, Setyorini; Fauzi, Ali Amali; Lillah, Alfarisi Syukron; Mariana, Ana; Nugrahani, Annisa Dewi
Indonesian Journal of Obstetrics & Gynecology Science Volume 8 Nomor 2 July 2025
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v8i2.883

Abstract

Objective: This study aimed to assess the association between COVID-19 severity and maternal and neonatal outcomes at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia.Methods: A retrospective cohort study was conducted among pregnant women with confirmed COVID-19 who delivered between March 1, 2020, and March 31, 2022. Patients were categorized by disease severity (asymptomatic, mild, moderate, severe, or critical). Demographic, clinical, maternal, and neonatal data were collected. Statistical analyses included Fisher’s exact and Kruskal-Wallis tests for bivariate analysis and Poisson regression for multivariate analysis (significance level α = 0.05).Results: Among 199 pregnant women, most were asymptomatic (42.7%) or had mild symptoms (37.2%). Higher COVID-19 severity was significantly associated with increased ICU/semi-ICU admission and oxygen therapy, as well as neonatal complications. After adjustment, moderate to critical cases showed significantly increased risks for ICU/semi-ICU care (p = 0.012, aRR 14.6; 95% CI: 1.8–118.2) and oxygen therapy (p = 0.001, aRR 12.2; 95% CI: 2.7–55.3). Mild cases were not linked to adverse outcomes.Conclusion: Moderate to critical COVID-19 during pregnancy is associated with higher risks of adverse maternal and neonatal outcomes, emphasizing the importance of early detection and close monitoring.Dampak Keparahan COVID- 19 pada Luaran Kehamilan: Studi Kohort di IndonesiaAbstrakTujuan: Penelitian ini bertujuan mengevaluasi hubungan antara tingkat keparahan COVID-19 dan luaran kehamilan serta neonatal di RSUP Dr. Hasan Sadikin, Bandung.Metode: Metode yang digunakan pada penelitian ini adalah kohort retrospektif pada ibu hamil dengan konfirmasi COVID-19 yang melahirkan antara 1 Maret 2020 hingga 31 Maret 2022. Pasien dikelompokkan berdasarkan tingkat keparahan (asimtomatik, ringan, sedang, berat, kritis). Data demografi, klinis, serta luaran ibu dan bayi dikumpulkan. Analisis statistik dilakukan menggunakan SPSS, dengan uji Fisher’s exact dan Kruskal-Wallis untuk bivariat, serta regresi Poisson untuk multivariat (α=5%).Hasil: Hasil penelitian menunjukkan dari 199 ibu hamil yang dianalisis, mayoritas bersifat asimtomatik (42,7%) atau ringan (37,2%). Keparahan penyakit yang lebih tinggi secara signifikan berhubungan dengan peningkatan kebutuhan perawatan ICU/semi-ICU dan terapi oksigen, serta komplikasi neonatal. Setelah penyesuaian, COVID-19 sedang–kritis berkorelasi dengan peningkatan risiko ICU/semi-ICU (p=0,012, aRR 14,6; 95% CI 1,8–118,2) dan terapi oksigen (p=0,001, aRR 12,2; 95% CI 2,7–55,3). Kasus ringan tidak menunjukkan hubungan dengan luaran buruk.Kesimpulan: Keparahan COVID-19 sedang hingga kritis pada kehamilan meningkatkan risiko luaran buruk sehingga diperlukan identifikasi dini dan pemantauan ketat.
Prediction of Height from Various Limb Measurement Syafira, Aisha Dinda; Huspa, Fitri Agustina; Wahyudi, Kurnia
Jurnal Forensik dan Medikolegal Indonesia Vol 6 No 1 (2025): Jurnal Forensik dan Medikolegal Indonesia
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jfmi.2025.6.1.13038

Abstract

Height has an important role in forensic medicine and clinical context, namely for biological profile identification of missing or unknown individuals and to provide an easier way to assess nutritional status of bedridden patients or elderly. This literature review aims to explore the variations in height prediction formulas based on limb bone length and to identify the advantages and limitations of these prediction techniques. Scientific studies were selected from Google Scholar, Scopus, and PubMed. Boolean operators and filters were applied to limit only relevant studies. The inclusion criteria in this research are research published in journals in the period 2019-2024, in the form of articles and not pre-prints, in Indonesian or English, research conducted on living humans, full research access-text and free. The exclusion criteria in this research are child and elderly research participants, research participants who suffer from certain diseases, and research using supporting examinations or artificial intelligence. These studies were then selected by using PRISMA flow. 30 articles were included in this study from 367 results. Most of the studies show that there is a positive correlation between stature and limb bone length. Therefore, height can be predicted by limb bone length but should consider population variations such as age, gender, ethnicity, nutritional status, and medical conditions. Keywords: stature, estimation, prediction, limb bone length