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Public Speaking Training in Building Self-Confidence as Optimal Preparation for the World of Work for Students of SMK Budi Asih, Jakarta Pradhana, Yudha; Vivitri Endah Andriani; Mira Adita Widianti; Firyal Nailah Khansa; Dinar Kadarsih; Albert Deniel Sitorus
Jurnal Pengabdian Kepada Masyarakat Vol. 1 No. 2 (2025): July 2025
Publisher : Ponpes As-Salafiyyah Asy-Syafi'iyyah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71305/jpkm.v1i2.221

Abstract

SMK Budi Asih, one of the secondary education institutions in Jakart, is responsible for producing graduates with technical ando good communication skills. Through speaking skills, students will be able to express ideas, thoughts, and information in the right way in public and not cause misunderstandings as optimal preparation for the world of work. This training is designed to improve students' speaking skills, self-expression, and effective communication so that they can face competitive challenges in the increasingly complex world of work. Involving interactive training methods, this activity not only focuses on the technical aspects of public speaking, but also strengthens the psychological aspects to overcome the fear of speaking in public. The results of this training can positively impact increasing self-confidence and preparing SMK Budi Asih students to face challenges in the dynamic world of work. The success of this training is expected to be measured through participant evaluation and monitoring the development of public speaking skills and increasing students' self-confidence.
Training on Issue and Crisis Management for Village Government Officials of Eureunpalay Village Cibalong Tasikmalaya Pradhana, Yudha; Andriani, Vivitri Endah; Febriani, Amadhea Zahra; Nur’aida, Tasya; Berliana, Ester; Roihandro, Mohammad Daffa
Jurnal Pengabdian Kepada Masyarakat Vol. 1 No. 2 (2025): July 2025
Publisher : Ponpes As-Salafiyyah Asy-Syafi'iyyah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71305/jpkm.v1i2.266

Abstract

The Issue and Crisis Management Training conducted for village government officials in Eureunpalay Village, Cibalong Subdistrict, Tasikmalaya, aimed to enhance effective communication skills in handling crisis situations. The training was attended by 20 participants, consisting of village apparatus and local community leaders. The initiative was motivated by the lack of understanding and practical skills among village officials in managing various issues and crises that may arise within the community, including natural disasters, social conflicts, and other emergency situations. Data collection methods included direct observation and open-ended interviews with participants to assess the development of their capacities throughout the training. The indicators of program success comprised: (1) increased participants' understanding of crisis communication techniques; (2) improved ability to apply vocal control, body language, and eye contact when speaking publicly; and (3) enhanced confidence in conveying messages during emergencies. The training outcomes showed a significant improvement in participants’ preparedness to face crisis situations, both in terms of technical communication skills and psychological readiness under pressure. The implications of these outcomes suggest that such training programs are a critical strategy in strengthening the capacity of village government officials, particularly in building effective communication during crises. Therefore, this initiative is recommended to be continued and scaled up to other villages as part of a broader effort to enhance local governance resilience.
Therapeutic Potential of Quercetin Derivatives: In Silico Investigation of HIV-1 Protease Inhibition Aziz, Husna Abdul; Camin, Yeremiah Rubin; Prasasty, Vivitri Dewi
Journal of Tropical Biodiversity Vol 4 No 2 (2024): April 2024
Publisher : Universitas Nasional Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59689/bio.v4i2.215

Abstract

Human Immunodeficiency Virus (HIV) type 1 is the predominant strain known for its impact on the immune system and its propensity for mutation. According to the World Health Organization (WHO), the global infection count reached 37.9 million in 2018, with alarming rates of mortality and morbidity. Ongoing drug discovery endeavors encompass various facets, including investigations into HIV protease—a key enzyme in the cleavage process of gag and gag-pol polyprotein chains essential for the genesis of new virions. While numerous studies suggest the inhibitory potential of quercetin against HIV-1, comprehensive exploration regarding its interaction with the HIV-1 protease receptor remains limited. This study aimed to elucidate the therapeutic potential of quercetin derivative compounds as viable candidates for HIV protease inhibition. Employing in silico analysis, molecular docking of 36 quercetin derivative compounds with the HIV-1 protease receptor (code 3SO9) using the Pyrx-Autodock Vina-Open Babel platform was conducted. Prior to docking, ligand preparation was meticulously performed using Autodock Tools 1.5.6, with geometry optimization utilizing Avogadro software. The interaction was assessed through Gibbs free energy (∆G) scoring, where a more negative ∆G value indicated a stronger binding propensity between the ligand and receptor. The docking results revealed that 22 quercetin derivative compounds exhibited Gibbs energy (∆G) values lower than the original ligand, darunavir. However, 5 compounds deviated from Lipinski's rule, while 17 compounds adhered to Lipinski's criteria. Consequently, these 17 quercetin derivative compounds exhibit promising potential as candidate drugs for HIV-1 protease inhibition.
Potential of Flavonoid Compounds from Rhodomyrtus tomentosa as Anticholesterol: An In Silico Study Lumbantoruan, Lamtiur; Sinaga, Ernawati; Simanjuntak, Kristina; Nurbaya, Siti; Prasasty, Vivitri Dewi
Journal of Tropical Biodiversity Vol 4 No 3 (2024): August 2024
Publisher : Universitas Nasional Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59689/bio.v4i3.232

Abstract

Indonesia's biodiversity ranks second largest in the world. This vast potential, if managed well, can be utilized as raw materials for medicines. Currently, 96% of drug raw materials in Indonesia are still imported, making medicines expensive. Therefore, efforts are needed to achieve self-sufficiency in drug raw materials, including researching Indonesian plants with potential as hypercholesterolemia drugs to be used as native raw materials. This study aims to determine the potential of flavonoid compounds in Rhodomyrtus tomentosa fruit as an alternative hypercholesterolemia drug. Six flavonoids were identified: myricetin, quercetin, quercetin 7,4'-diglucoside, dihydromyricetin, kaempferol, and vitexin in R. tomentosa (Karamunting) fruit. The method used was an in silico study. In silico studies are used to screen compounds based on their mechanism of action against target proteins. In this study, myricetin, quercetin, dihydromyricetin, kaempferol, quercetin 7,4'-diglucoside, and vitexin were subjected to molecular docking using Autodock Vina software to determine the affinity and interaction of these six compounds with the HMG-CoA reductase enzyme, which acts as an intermediary in the mevalonate pathway for cholesterol metabolism. Simvastatin, a drug used for hypercholesterolemia treatment, was used as a comparison. The molecular docking results showed that the binding energy values for myricetin, quercetin, dihydromyricetin, kaempferol, quercetin 7,4'-diglucoside, and vitexin were -10.0, -9.4, -9.6, -9.2, -11.4, and -9.9 kcal/mol, respectively. These six flavonoid derivatives from Karamunting fruit have better inhibition scores compared to simvastatin, indicating that these flavonoid derivatives can inhibit cholesterol biosynthesis better than simvastatin and have potential as anticholesterol drugs.
Anti-Aging Potential of Moringa oleifera Bioactive Compounds: A Molecular Docking Approach Targeting Sirtuin Proteins Marthin, Jeffrey; Noverita, Noverita; Prasasty, Vivitri Dewi
Journal of Tropical Biodiversity Vol 5 No 2 (2025): April 2025
Publisher : Universitas Nasional Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59689/bio.v5i2.268

Abstract

Moringa oleifera has long been valued in traditional skincare, but its molecular interactions with key aging regulators remain poorly understood. This study elucidates the anti-aging potential of Moringa oleifera bioactive compounds through their modulation of sirtuin proteins (SIRT2, SIRT5, SIRT6), which govern genomic stability and oxidative stress responses. Using computational approaches, we performed molecular docking simulations (AutoDock Vina) on 20 bioactive compounds against sirtuin crystal structures from the Protein Data Bank. Comparative analysis with commercial anti-aging agents (niacinamide, AHA, ceramide) identified three Moringa compounds with superior binding affinities: rutin (-10.7 kcal/mol), quercetin (-8.9 kcal/mol), and chlorogenic acid (-7.9 kcal/mol), all outperforming niacinamide (-6.1 kcal/mol). SwissADME profiling confirmed their drug-like properties, including high oral bioavailability, blood-brain barrier penetration, and minimal toxicity risks. Mechanistically, these compounds demonstrated dual antioxidant and anti-inflammatory capacities, suggesting synergistic protection against oxidative damage and inflammation-driven aging. Our results position Moringa oleifera as a rich source of multitarget anti-aging candidates, combining computational validation with biological relevance to advance natural product-based interventions against cellular senescence.
Implementasi Pemasaran Digital Melalui Instragram untuk Mengenalkan Kesenian Khas Cirebon Widianti, Mira Adita; Andriani, Vivitri Endah; Ramadhan, Muhammad Alfahrezi Baihaqi
Warta Ikatan Sarjana Komunikasi Indonesia Vol 7, No 1 (2024): Juni 2024
Publisher : Ikatan Sarjana Komunikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25008/wartaiski.v7i1.269

Abstract

Media sosial memiliki fungsi memberi informasi kepada masyarakat ingin mengetahui berbagai hal tertentu. Melalui media sosial para pengguna dapat berpartisipasi aktif interaktif secara terbuka untuk menyampaikan, menerima dan mendiskusikan ide-ide baru sebagai dasar pembuatan keputusan bisnis. Untuk memberitahukan kepada halayak tentang kesenian khas kota Cirebon, Sanggar seni Sekar Pandan memerlukan konten-konten yang dapat menarik perhatian masyarakat luas. Konten-konten yang diperlukan oleh sanggar seni Sekar Pandan adalah konten yang mendidik, menghibur, dan bermanfaat bagi masyarakat luas. Fokus penelitian ini adalah bagaimana sanggar seni Sekar Pandan mengembangkan konten-konten media sosial instagram mereka guna memperkenalkan sanggar mereka dan juga kebudayaan Kota Cirebon. Data diambil dari wawancara dengan pengelola sanggar seni Sekar Pandan dan menganalisis media sosial Sekar Pandan. Temua penelitiannya adalah, sanggar seni Sekar Pandan melalui pesan-pesannya di intagram, berhasil mengenalkan berbagai kegiatan seni yang dilaksanakan dengan menerapkan pemasaran digital di media sosial.  
Netizen Journalism on Instagram as Local Digital Media and Communication Dynamics in the @infobekasi Account Widianti, Mira Adita; Putra, Ariandi; Andriani, Vivitri Endah
COMMUSTY Journal of Communication Studies and Society Vol. 4 No. 2 (2025)
Publisher : Universitas Pendidikan Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38043/commusty.v4i2.7436

Abstract

This study examined the communication dynamics of netizen journalism within the Instagram account @infobekasi as a local digital media platform in Bekasi. The study was conducted to address the limited understanding of how local social media accounts mediate citizen participation, content curation, and information dissemination. A qualitative research design with a descriptive–interpretative approach was employed. Primary data were collected through documentation of Instagram content, including posts and audience interactions, and were analyzed inductively through data reduction and thematic categorization. The findings showed that @infobekasi functioned as a hybrid media platform that integrated citizen-generated content, administrative curation, and audience interaction. The account also served as a local digital early warning system by enabling rapid circulation and social verification of local information. The study concluded that netizen journalism on social media reflected the transformation of local media practices in the digital era.