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KEJADIAN INFEKSI PASCA VAKSINASI COVID-19 DOSIS PRIMER PADA SASARAN VAKSIN LANJUTAN DI SENTRA VAKSINASI COVID-19 UNIVERSITAS TARUMANAGARA Wiyarni Pambudi; Sari Mariyati Dewi Nataprawira; Andria Priyatna; Yoanita Widjaja; Jennefer; Sannya Christy
Jurnal Muara Medika dan Psikologi Klinis Vol. 2 No. 2 (2022): Jurnal Muara Medika dan Psikologi Klinis
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Tarumanagara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24912/jmmpk.v2i2.24455

Abstract

Pemberian vaksinasi COVID-19 dosis primer telah dilakukan di Sentra Vaksinasi UNTAR pada bulan Maret hingga Agustus 2021 menggunakan vaksin Sinovac dan Astra Zeneca. Vaksinasi lanjutan dosis booster pertama diberikan pada bulan Februari 2022 kepada sasaran yang sama dengan interval minimal enam bulan, menggunakan vaksin Moderna, sesuai ketersediaan vaksin yang dibagikan oleh Dinas Kesehatan DKI Jakarta melalui Puskesmas Kecamatan Grogol Petamburan, Jakarta Barat. Penelitian dengan desain potong lintang ini bertujuan mengetahui angka kejadian terkonfirmasi COVID-19 setelah vaksinasi dosis primer pada sasaran vaksinasi yang dilayani oleh Sentra Vaksinasi UNTAR. Selama tiga hari pelayanan vaksin lanjutan dosis booster pertama tercatat 672 sasaran Sentra Vaksinasi UNTAR, terdiri atas warga usia lanjut di atas 60 tahun 264 (39,4%), usia 25-59 tahun 359 (53,4%), usia 18-24 tahun 48 (7,2%), berjenis kelamin laki-laki 348 (51,9%) dan perempuan 322 (48,1%). Sejumlah 19 (2,8%) sasaran menyatakan terkonfirmasi COVID-19 pasca vaksinasi dosis primer, dan 39 (5,8%) sasaran memiliki riwayat terinfeksi COVID-19 sebelum mendapatkan vaksin dosis primer. Riwayat terkonfirmasi COVID-19 lebih tinggi pada kategori usia 25-59 tahun (32/58, p=0,128) dan tidak berbeda pada jenis kelamin laki-laki dan perempuan. Individu yang terkonfirmasi COVID-10 setelah mendapat vaksin dosis primer mempunyai komorbid hipertensi, diabetes melitus, dan penyakit lain (p=0,017). Gejala yang dirasakan antara lain mudah lelah, nyeri sendi, nyeri kepala, diare, dan keluhan lain yang lazim terjadi pada kasus COVID-19 ringan, mencerminkan adanya peningkatan imunitas sebagai efek dari vaksinasi dosis primer.
Kualitas tidur dan gejala gangguan saluran pernapasan atas pada mahasiswa kedokteran Universitas Tarumanagara angkatan 2019-2020 Thalia Natasha; Sari Mariyati Dewi Nataprawira; Susy Olivia Lontoh
Tarumanagara Medical Journal Vol. 5 No. 2 (2023): TARUMANAGARA MEDICAL JOURNAL
Publisher : Fakultas Kedokteran Universitas Tarumanagara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24912/tmj.v5i2.25276

Abstract

Tidur dapat mempengaruhi sistem imun serta diatur oleh irama sirkadian yang menentukan waktu untuk tidur dan homeostasis tidur yang menentukan durasi tidur. Deprivasi tidur dan insomnia merupakan gangguan tidur yang menyebabkan menurunnya kualitas tidur. Kualitas tidur yang buruk dapat mempengaruhi produktivitas kerja dan penurunan sistem imun sehingga meningkatkan resiko terjadinya suatu penyakit, salah satunya pada saluran pernapasan atas. Mayoritas mahasiswa kedokteran memiliki kualitas tidur yang buruk. Kualitas tidur yang buruk meningkatkan resiko terjadinya common cold. Tujuan studi ini adalah mendapatkan gambaran kualitas tidur dan gejala di saluran pernapasan atas pada mahasiswa Fakultas Kedokteran Universitas Tarumanagara selama semester berlangsung. Studi dengan desain deskriptif cross-sectional terhadap 150 responden angkatan 2019-2020 ini menggunakan teknik consecutive sampling untuk pengambilan sampel dan dilakukan selama Desember 2022. Instrumen yang digunakan adalah kuesioner Pittsburgh Sleep Quality Index (PSQI) dan kuesioner gejala gangguan saluran pernapasan atas. Hasil didapatkan mayoritas jenis kelamin perempuan (72.7%) dengan rentang usia 19-25 tahun. Gambaran kualitas tidur dan gejala di saluran pernapasan atas didapatkan kualitas tidur yang buruk (84%) dan hanya 26,7% yang tidak bergejala namun pada kelompokan yang mengalami gejala mayoritas mengalami bersin (83,6%). Pada pengelompokkan kualitas tidur didapatkan gejala bersin merupakan frekuensi tertinggi baik pada kelompok kualitas tidur baik (34.2%) dan kualitas tidur buruk (31.3%).
Edukasi Pola Hidup Bersih dan Sehat pada remaja di Gereja HKBP Villa Duta Mas Bogor Triyana Sari; Erick Sidharta; Sari Mariyati Dewi Nataprawira; Yovian Timothy Satyo; Fladys Jashinta Mashadi
Jurnal Pengabdian Bidang Kesehatan Vol. 1 No. 4 (2023): Jurnal Pengabdian Bidang Kesehatan
Publisher : PPNI UNIMMAN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jpbidkes.v1i4.12

Abstract

Clean and Healthy Lifestyle (PHBS) is one of the Ministry of Health's Community Movement (Germas) programs, where the community acts as an agent of change and improves the quality of daily behavior towards a clean and healthy life. The advantage of PHBS is that people are health aware and have the knowledge and awareness to live a clean and healthy lifestyle. As a public place, the church organizes various activities that many groups, from children to adults, can take part in. Apart from that, the church also plays a role in spiritual and physical education, meaning that children and teenagers not only gain spiritual knowledge, but also physical knowledge for everyday life. This activity aims to increase knowledge and awareness about clean and healthy living behavior from an early age.
Effect of Degree of Smoking Based on Brinkman Index on Hemoglobin Levels in Adults Wijaya, Bryan Anna; Sari Mariyati Dewi Nataprawira
Community Medicine and Education Journal Vol. 5 No. 2 (2024): Community Medicine and Education Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/cmej.v5i2.574

Abstract

Cigarette consumption is the main cause of death in the world because it affects various physiological conditions in the body. Various ingredients in cigarette smoke such as tar, nicotine, carbon monoxide, and others can cause health problems, especially in the O2 transportation system. Hemoglobin is a protein in red blood cells that carries oxygen from the lungs to all tissues. The carbon monoxide contained in cigarette smoke is competitive with O2 in binding to hemoglobin so that the oxygen distributed to the tissues is reduced. The body will compensate for peripheral hypoxia that occurs by increasing hemoglobin levels in the body so that oxygen transport to the tissues can be maintained. Research regarding the relationship between the degree of smoking and hemoglobin levels is still controversial. Analytical research with cross-sectional design. A total of 184 respondents were taken using purposive sampling and it was found that the majority (94%) were men who worked as security officers, cleaners, parking attendants, or technicians. Based on the Brinkman Index, 73.9% of respondents were classified as light smokers, only 1.6% were classified as heavy smokers and 50.5% of respondents had low hemoglobin levels. Analysis showed that the majority of respondents in the light smoker group had normal hemoglobin levels (58.1%), while moderate and heavy smokers had lower hemoglobin levels. In statistical analysis, a significant p-value (0.001) was found between the degree of smoking and hemoglobin levels.
Demensia : Patofisiologi, Faktor Resiko dan Peran Inflamasi dalam Perkembangan Penyakit Erick Sidarta; Triyana Sari; Sari Mariyati Dewi Nataprawira
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 3 No. 1 (2025): Januari : Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v3i1.4801

Abstract

Dementia is a complex neurodegenerative syndrome characterized by cognitive decline, including memory impairment, difficulty in thinking, and social interaction, which can affect daily activities. This condition is often caused by other diseases, including Alzheimer’s disease, vascular dementia, Lewy body dementia, and frontotemporal dementia, each with unique pathological mechanisms. Alzheimer’s disease, the leading cause of dementia, involves the accumulation of beta-amyloid plaques and tau tangles that disrupt neuronal function and trigger chronic inflammation. Vascular dementia results from impaired blood flow to the brain, while Lewy body dementia is associated with the misfolding of alpha-synuclein protein. Meanwhile, frontotemporal dementia is linked to the accumulation of tau or TDP-43 proteins, causing degeneration of the frontal and temporal lobes. Aging is the primary risk factor for dementia through the process of inflammaging, a low-grade chronic inflammation caused by persistent activation of the immune system. Inflammaging accelerates neurodegeneration by increasing oxidative stress, mitochondrial dysfunction, and the accumulation of pathological proteins. Additionally, neuroinflammation plays a crucial role by over activating microglia, which exacerbates neuronal damage. The combination of inflammation as both a trigger and a consequence create a pathological cycle that accelerates the progression of dementia. Preventive strategies include managing modifiable risk factors such as hypertension, diabetes, obesity, and adopting a healthy lifestyle, alongside developing therapies targeting inflammaging and neuroinflammation. A deeper understanding of these pathophysiological and inflammatory mechanisms is essential to support the development of multidisciplinary interventions to reduce the global burden of dementia.
HEALTHY AND PRODUCTIVE LIFESTYLE EDUCATION FOR YOUTH AT SENIOR HIGH SCHOOL KALAM KUDUS 2 JAKARTA Ernawati, Ernawati; Yohanes Firmansyah; Alexander Halim Santoso; Sukmawati Tansil Tan; Noer Saelan Tadjudin; Sari Mariyati Dewi Nataprawira; Susy Olivia Lontoh; Hendsun, Hendsun; Fendy Wellen; Jeffry Luwito; Valeria Saputra; Stanley Surya Cahyadi; Muhamad Rizki Nanda F
Jurnal Pelayanan dan Pengabdian Masyarakat Indonesia Vol. 1 No. 4 (2022): Desember : Jurnal Pelayanan dan Pengabdian Masyarakat Indonesia
Publisher : Sekolah Tinggi Ilmu Administrasi Yappi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (512.008 KB) | DOI: 10.55606/jppmi.v1i4.92

Abstract

Clean and Healthy Living Behavior is an endeavor to live a healthy lifestyle at both the individual and communal levels. In the current pandemic era, it is crucial to focus on Clean and Healthy Living Behavior in order to avoid various viruses and diseases. The necessity of Clean and Healthy Behavior must continue to be emphasized to all segments of society. Youth is a group that need attention. According to a situational analysis conducted at SMA Kalam Kudus II in Jakarta, there is a problem with poor levels of cleanliness and health consciousness. To raise high school students' understanding of clean and healthy lives, it is required to conduct activities such as lectures, discussions, and outreach. This service activity takes place in Kalam Kudus II Jakarta High School. This service action was accomplished by performing a survey of service sites, preparing service locations, and delivering Clean and Healthy Behavior support resources. Youth members have participated in Clean and Healthy Living Behavior socialization activities using lecture, discussion, and question and answer formats. This service activity worked smoothly overall. The conclusion that can be derived from this is that service activity participants recognize the significance of clean and healthy lifestyle choices in preventing various diseases.
DEVELOPMENT OF AMPLIFICATION REFRACTORY MUTATION SYSTEM PCR TO DETECT ANDROGEN RECEPTOR GENE G1773A (RS6152) POLYMORPHISM Triyana Sari; Erick Sidarta; Sari Mariyati Dewi Nataprawira; Giovani Evangelista Alfonsius; Damar Sajiwo
Jurnal Scientia Vol. 12 No. 03 (2023): Education, Sosial science and Planning technique, 2023 (June-August)
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Androgen receptor (AR) is a ubiquitous receptor responsible for responses by androgen stimulus. Androgen, a hormone which will bind to the AR, is essentials for normal male sexual development. Nevertheless, one of the polymorphisms in the AR gene, G1733A (rs6152) have been associated with numerous clinical risks such as cardiovascular disease (CD), androgenetic alopecia, high prostate-specific antigen (PSA) levels, male infertility, recurrent spontaneous abortions and prostate cancer. This study aims to develop an alternative and cost-effective method to detect G1773A (rs6152) polymorphism. In this study, amplification refractory mutation system-polymerase chain reaction (ARMS-PCR) using two pair of primers was used to detect the G1733A (rs6152) polymorphism. Primer design was done using http://primer1.soton.ac.uk/primer1.html online tools and then manually adjusted to increase the specificity. A total of 54 samples were screened using ARMS PCR and 2 representative samples of each allele from previous screening were used to validate the results using Sanger DNA sequencing. Among 54 subjects screened, we found 52 (96.3%) subjects carry G allele and 2 (3.7%) subjects carry A allele. No heterozygote was found in this study. The frequency of G allele was 96.97% and the frequency of A allele was 3.03%. Result validation using DNA sequencing was in agreement with ARMS-PCR method results. ARMS-PCR can be used as efficient alternative for genotyping of G1733A (rs6152) AR gene polymorphism
Pelatihan Bantuan Hidup Dasar (BHD) untuk Meningkatkan Kesiapsiagaan Komunitas Karang Taruna di Kelurahan Kota Bambu, Jakarta Barat Sari Mariyati Dewi Nataprawira; David Limanan; Alexander Halim Santoso; Muhammad Fikri Dzakwan
JPMNT JURNAL PENGABDIAN MASYARAKAT NIAN TANA Vol. 3 No. 3 (2025): Juli: Jurnal Pengabdian Masyarakat Nian Tana
Publisher : Fakultas Ekonomi & Bisnis, Universitas Nusa Nipa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59603/jpmnt.v3i3.997

Abstract

Cardiac arrest is a critical medical emergency with a high mortality rate that requires immediate and appropriate action to increase the chances of survival. One key factor in improving survival outcomes is the involvement of bystanders, particularly young people, in providing Basic Life Support (BLS). This community service activity was carried out to improve the knowledge and practical skills of youth organization members (Karang Taruna) in Kota Bambu Subdistrict, West Jakarta, in recognizing and responding to cardiac arrest using BLS procedures. The activity adopted the PDCA (Plan-Do-Check-Act) approach. The planning stage involved the preparation of materials and training tools for both theoretical and practical learning. The implementation phase included a 45-minute health education session covering the basics of BLS, especially cardiopulmonary resuscitation (CPR), followed by hands-on training. Participants were divided into small groups and guided through practical CPR simulations using manikins, facilitated by six trained nursing students. The activity was conducted on June 14, 2025, and attended by 57 participants, with 27 actively participating in the CPR practice session. The evaluation stage revealed a notable increase in the participants’ understanding and ability to perform CPR effectively. This indicates that community-based BLS training can be a powerful tool in improving emergency response at the grassroots level. In addition to raising awareness, the activity also empowered the youth as first responders in their community, strengthening their role in emergency preparedness and response. The follow-up stage emphasized the importance of sustainability through continued collaboration between local health professionals and community organizations. In conclusion, BLS education and training programs for youth can significantly enhance community resilience and are recommended for broader implementation in other regions.