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Journal : Journal of Innovation Research and Knowledge

EFEKTIVITAS INFUSA JAHE MERAH (ZINGIBER OFFICINALE VAR. RUBRUM) SEBAGAI ANTIDIARE PADA MENCIT PUTIH JANTAN YANG DI INDUKSI OLEUM RICINI DENGAN METODE TRANSIT INTESTINAL Yulis Azizah; Rizka Mulya Miranti; Dedi Hartanto; Retna Eka Dewi
Journal of Innovation Research and Knowledge Vol. 3 No. 3: Agustus 2023
Publisher : Bajang Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53625/jirk.v3i3.6348

Abstract

Red ginger is a plant of the Zingiberaceae family which contains active compounds which are consider to have a major contribution to the anti-diarrheal effect are steroids, tannins, flavonoids, and saponins. The purpose of this study was to determine if red ginger infusion has an antidiarrheal effect and what is the effective dose if it has an anti- diarrheal effect. This research is an experimental with a Completely Randomised plan (CRP) with a one way model. Twenty-four mice were randomly assigned to 6 groups of 4 mice within each group. The Red ginger infusion was tested with 3 different dosage variations; 1.047 g/kgBW, 2.095 g/kgBW, and 4.19 g/kgBW. The Antidiarrheal activity in this study was determined by computing the ratio of the bowel length passed through the marker to total length of the intestine. The results showed that red ginger infusion has an anti-diarrheal effect. Infusion of red ginger at doses of 1.047 g/kg BB, 2.095 g/kg BB and 4.19 g/kgBW, resulting in average ratios of 0.596, 0.37975 and 0.164125, consecutively. Based on a statiscal data analysis with the Mann Whitney Test, it was obtained that the ratio between a dose of 4.19 g / kgBW and the Loperamide comparison group of 4 mg / kgBW dose did not have a meaningful difference. So the most effective dose of red ginger infusion as an anti-diarrhea is 4.19 g/kgBW.
GAMBARAN KESESUAIAN PERESEPAN TERHADAP KETERSEDIAAN OBAT PUSKESMAS X DI BANJARMASIN SELATAN PERIODE DESEMBER 2021 Retna Eka Dewi
Journal of Innovation Research and Knowledge Vol. 3 No. 3: Agustus 2023
Publisher : Bajang Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53625/jirk.v3i3.6350

Abstract

Appropriateness of prescribing with the availability of medicine is a cycle that influences each other with the rational use of drugs. Rational prescribing is if the patient receives treatment appropriately in doses, in periods, and at affordable cost according to his clinical needs. This study aims to describe the appropriateness of prescriptions for medicine availability at the Public Health Center X in South Banjarmasin for the period of December 2021. This type of research uses a retrospective descriptive method with samples was take by random sampling. The results showed that of the 328 prescriptions, there was an inappropriate with the type of drug found as much as 29.57%, with the drug strength found as much as 12.50%, with the dosage form found as much as 1.52%, with the duration of administration was found to be 1.22%, for the route of drug administration it had 100% appropriate. The results of this study indicate that the incompatibility of the type of drug has the highest percentage, namely 29.57%.