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All Journal Jurnal Ilmiah Manuntung AL-ULUM: JURNAL SAINS DAN TEKNOLOGI Jurnal Pengabdian Masyarakat Bangsa
Sa'adah, Hayatus
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PERBANDINGAN PELARUT ETANOL DAN AIR PADA PEMBUATAN EKSTRAK UMBI BAWANG TIWAI (Eleutherine americana Merr) MENGGUNAKAN METODE MASERASI Sa'adah, Hayatus; Nurhasnawati, Henny
Jurnal Ilmiah Manuntung Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (340.585 KB) | DOI: 10.51352/jim.v1i2.27

Abstract

Bawang tiwai (Eleutherine americana Merr) is one kind of medicinal plant. To obtain an active substances with good physical and chemical properties, it is needs to do optimization of making extracts, one with solvent optimization. Type of solvent will determine the types of extracted substances in accordance with the polarity. On this research, extraction of bawang tiwai bulbs simplicia by maceration method using ethanol and water as solvent. This research is an experimental research with varying ethanol and water in a three comparison solvent that is water, ethanol, and mixture of water-etanol, then the yields is calculated. Furthermore, the data were analyzed statistically using ANOVA program to determine significant differences in the three yields. In each extract was conducted phytochemical screening to determine the content of secondary metabolites. The results showed significant differences in the yield of bawang tiwai extract with three treatments and two repetitions. The results of average yields using water as solvent is 8.75%, ethanol 5.3%; and water-etanol 8.31%
FORMULASI ORALLY DISINTERGRATING TABLET (ODT) EKSTRAK ETANOL DAUN KEMANGI (Ocimum americanum L.) DENGAN VARIASI KONSENTRASI EXPLOTAB® Soemarie, Yulistia Budianti; Sa'adah, Hayatus; Marginingsih, Tri
Jurnal Ilmiah Manuntung Vol 4 No 1 (2018): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (320.042 KB)

Abstract

Bad breath is usually caused by bacteria and leftovers in the mouth. Utilization of natural ingredients that can be used to overcome the problem of bad breath one of them by using basil leaves (Ocimum americanum L.), which has activity as an antibacterial. The development of the preparations was done on basil leaves to overcome bad breath is by formulating the basil leaves ethanol extract into the Orally Disintegrating Tablet (ODT) preparation. The purpose of this study was to investigate the effect of explotab® concentration variations on the physical properties of ODT and to determine the best of concentrations of Explotab® that fulfill the physical properties of ODT. The type of research conducted was an experimental study. Research object was basil leaves ethanol extract formulated into ODT with Explotab® 2% w/b, 4% w/w, 6% w/b and 8% w/w variation. Physical evaluations test then conducted including : the uniformity of weight evaluation, the hardness test, the friability test, and the dissolved time. The results showed that the explotab® concentration variations had an effect on the physical properties of tablets and the formula with the Explotab® 8% b/b concentration was the best formula that could produce the best ODT tablet with physical properties.   Keywords    :    Basil leaves (Ocimum americanum L.), Explotab®, Orally Disintegrating Tablet (ODT)
FORMULASI DAN UJI PERTUMBUHAN RAMBUT KELINCI DARI SEDIAAN HAIR TONIC KOMBINASI EKSTRAK DAUN SELEDRI (Apium graveolens Linn) DAN DAUN MANGKOKAN (Polyscias scutellaria (Burm.f.) Fosberg) Jubaidah, Siti; Indriyani, Ria; Sa'adah, Hayatus; Wijaya, Heri
Jurnal Ilmiah Manuntung Vol 4 No 1 (2018): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (330.371 KB)

Abstract

Apium graveolens Linn and Polyscias scutellaria (Burm.f.) leaves are empirically widely used to stimulate hair growth. The purpose of this research is to combine celery leaf extract and mangkokan leaf extract formulated in hair tonic. The hair tonic preparations made were evaluated by performing a physical test of the preparation and knowing the best concentration of celery leaf extract and mangkokan leaf extract on rabbit hair growth. The hair tonic were prepared in 3 formulations with the ratio of Celery leaf extract and mangkokan leaf extract (5:5 ; 7,5:2,5 and 2.5:7,5)% w / v. The positive control used is hair tonic Minoxidil 2%. Physical tests of the preparation include organoleptic test, pH and viscosity test. Hair growth activity test is done by applying hair tonic on the 3 rabbits shaved hair and hair growth measurements until the 21st day. The data of hair growth measurements were tested statistically by ANOVA test method. Based on the research result, it can be concluded that hair tonic combination of celery leaf extract and mangkokan leaf extract with ratio (7.5: 2,5)%, has average hair length 2,459 cm and hair weight 0,199 g is the optimum concentration in stimulating hair growth activity with positive control has average hair length 2,493 cm and hair weight 0,285 g. Test statistically there was no significant difference between extract and positive control.   Keywords : Apium graveolens Linn, Polyscias scutellaria (Burm.f.) Fosberg, hair tonic.
OPTIMASI FORMULA EKSTRAK JAHE MERAH (Zingiber officinale) DENGAN METODE KEMPA LANGSUNG MENGGUNAKAN ANALISIS SIMPLEX LATTICE DESIGN Sa'adah, Hayatus
Jurnal Ilmiah Manuntung Vol 1 No 1 (2015): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (52.474 KB) | DOI: 10.51352/jim.v1i1.11

Abstract

Processing of medicinal plants into the appropriate dosage form can ensure security during use. It is a motivation in making acceptable dosage form which is easy and convenient to use, especially the manufacture of ethanol extract red ginger tablets using a combination of starch 1500 and amprotab.The study begins with the manufacture of dry extract of red ginger. Optimization of making tablets using a combination of starch 1500 and disintegrator with simplex lattice design using three formulas is done by direct compaction method. Further testing on the tablet hardness, friability and disintegration time.The results showed starch 1500 has a greater influence increase hardness and disintegration time of tablets, as well as lowering the fragility of the tablet. While the interaction of starch 1500 and disintegrator has no effect on the physical tablet. The optimum proportion of the combination of starch 1500 and disintegrator meet the physical requirements of tablets with a ratio of 4: 6 with 7.99 kg hardness, the friability of 0.32% and disintegration time of 2.42 minutes
UJI MUTU FISIK GRANUL EKSTRAK ETANOL DAUN KEMANGI (Ocimum americanum L.) DENGAN VARIASI KONSENTRASI EXPLOTAB® Soemarie, Yulistia Budianti; Sa'adah, Hayatus; Fatimah, Nurul; Ningsih, Tri Marga
Jurnal Ilmiah Manuntung Vol 3 No 1 (2017): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (219.096 KB)

Abstract

Bad breath is usually caused by bacteria and food debris left in the mouth. Development of preparations using herbal ingredients, to overcome the problem of bad breath one of them is with utilization basil leaves (Ocimum americanum L.) which have anti bacterial activity. The method of wet granulation is a single method for use in granulation of large doses of active substances because if using direct induced method will require again the addition of a large number of fillers to make it easier forging, but cause the tablet to be not feasible as it will resulting in an increase in tablet size. The type of research conducted is an experimental study. Object the study was basil leaf extract formulated. This formulation was prepared by wet granulation method with variation Explotab® ss crusher ie 2%, 4%, 6% and 8%. Performed wet granulation on each formulation. Granul evaluated the flow time, mass density test, silent angle and fixed assay test. Based on research result the physical quality of ethanol extract granule of basil leaves (Ocimum americanum L.) with explotab® concentration variation it can be concluded that all the formula fulfill the good quality of granule characteristic, because it meets the requirements of parameters of time flow, rest angle, compressibility and density mass
Edukasi Penyakit Gastritis Sejak Dini: Cegah Sakit Ciptakan Fokus Belajar di Lingkungan SMP Negeri 6 Banjarbaru Sa'adah, Hayatus; Latifah, Nor; Zamzani, Irfan; Ahdyani, Risa; Dewi, Retna Eka; Padjrin, Muhammad Awaluddin; Makki, Makki; Mahmudah, Mahmudah; Azzahra, Maulida
Jurnal Pengabdian Masyarakat Bangsa Vol. 2 No. 6 (2024): Agustus
Publisher : Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/jpmba.v2i6.1244

Abstract

Tujuan dari penyuluhan ini adalah untuk memberikan edukasi tentang definisi, penyebab, gejala dan terapi farmakologi atau non-farmakologi dari penyakit gastritis pada remaja sejak dini untuk pencegahan sehingga dapat meningkatkan fokus belajar. Metode yang digunakan adalah metode KIE (Konseling Informasi dan Edukasi) oleh Dosen dan Mahasiswa S1 Farmasi/Fakultas Farmasi Universitas Muhammadiyah Banjarmasin, dilaksanakan secara offline di SMPN 6 Banjarbaru. Berdasarkan hasil KIE kepada Siswa SMPN 6 Banjarbaru, mereka sudah mengetahui penyakit Gastritis dengan nama lain Maag, Sebagian besar pernah mengalami gastritis disebabkan karena tidak sarapan agar sampai ke sekolah tepat waktu. Dengan adanya KIE ini, siswa lebih memahami penyakit gastritis, pengobatan dan pencegahannya.
TOTAL FLAVONOID CONTENT OF KAPUL FRUIT PEEL EXTRACT (Baccaurea macrocarpa) BASED ON SOLVENT TYPE VARIATION USING UV-VIS SPECTROPHOTOMETRY Rahmadani, Rahmadani; Supriningrum, Risa; Sa'adah, Hayatus
AL ULUM: JURNAL SAINS DAN TEKNOLOGI Vol 10, No 3 (2024)
Publisher : UPT Publication and Journal Management, Islamic University of Kalimantan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31602/jst.v10i3.16642

Abstract

The solvent type plays a crucial role in influencing the extraction of active compounds from natural materials. The peel of kapul fruit (Baccaurea macrocarpa) is known to contain flavonoid compounds with notable antibacterial properties. This study aimed to quantify the total flavonoid content in kapul fruit peel extract by evaluating the effects of different solvent types using the UV-Vis spectrophotometric method. The analysis revealed the presence of secondary metabolites, including alkaloids, saponins, and flavonoids. The total flavonoid content of the kapul fruit peel extract varied significantly across different solvents: 4.7238 ± 0.5807 mgQE/g for ethanol, 2.9699 ± 0.1539 mgQE/g for ethyl acetate, and 2.0417 ± 0.4236 mgQE/g for n-hexane. Statistical analysis demonstrated a significant difference in flavonoid content among the three solvent extracts. These results highlight the importance of solvent selection in maximizing the extraction efficiency of flavonoids from kapul fruit peel, which may have implications for its potential therapeutic applications.
Co-Authors Ahdyani, Risa Azzahra, Maulida Dewi, Retna Eka Henny Nurhasnawati Heri Wijaya, Heri Indriyani, Ria M. Awaluddin Padjrin Mahmudah Mahmudah Makki, Makki Marginingsih, Tri Ningsih, Tri Marga Nor Latifah Nurul Fatimah Rahmadani Rahmadani Risa Supriningrum Siti Jubaidah, Siti Soemarie, Yulistia Budianti Zamzani, Irfan