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All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Journal of Biomedicine and Translational Research Mutiara Medika: Jurnal Kedokteran dan Kesehatan Dharma Raflesia : Jurnal Ilmiah Pengembangan dan Penerapan IPTEKS Jurnal Kesehatan Tambusai Indonesian Journal of Multidisciplinary Science Jurnal Ilmiah Pengabdian Masyarakat Bidang Kesehatan Bencoolen Journal of Pharmacy Biodiversitas Journal of Biological Diversity
Suryani, Utari Hartati
Departemen Mikrobiologi Fakultas Kedokteran Dan Ilmu Kesehatan Universitas Bengkulu
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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PEMANFAATAN MINI MENTAL STATE EXAM (MMSE) OLEH DOKTER-DOKTER PUSKESMAS UNTUK DETEKSI DINI GANGGUAN DEMENSIA PADA ORANG TUA LANJUT USIA (LANSIA) DI KABUPATEN BENGKULU UTARA Suryo Bantolo; Zayadi Zainuddin; Utari Hartati Suryani
DHARMA RAFLESIA Vol 13, No 2 (2015): DESEMBER
Publisher : Universitas Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/dr.v13i2.4244

Abstract

One of the health problems in the elderly are dementia disorder, or better known to laymen as senile. About 5% of 65-70 year old age suffer from dementia and has doubled every 5 years reached 45% at the age of 85 years. The purpose of this activity is to equip doctors of health centers to implement the use of MMSE as a screening tool that is sustainable for the prevention of disorder dementia in the elderly. The methods of these activities by providing direct training to the general practitioners to use the MMSE. Training activities and practice the use of MMSE for clinics doctors in North Bengkulu district has been going smoothly after the expected. It is necessary synergy between health centers, hospitals and health authorities to monitor this activity and follow up on the elderly who experience these dementia. Keywords: Dementia, MMSE, Training  
Interrelation between Handwashing and the Severity of COVID-19: A non-representative cross-sectional study Nabila Putri Firdalina; Riry Ambarsarie; Utari Hartati Suryani; Dessy Triana; Nikki Aldi Massardi
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 22, No 2 (2022): July
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v22i2.14248

Abstract

Corona Virus Disease 2019 (COVID-19) pandemic remains a global issue, including in Indonesia. Handwashing using soap can reduce the viral load of the SARS-CoV-2 virus and prevent coinfection, which can worsen symptoms in COVID-19 patients. This study aims to determine the relationship between knowledge, attitudes, and handwashing behavior to the severity of COVID-19. Research using a cross-sectional and retrospective approach was conducted from July to December 2020 in Bengkulu Province. About 107 respondents had been confirmed positive for Covid-19 with the rt-PCR test, aged 17-60 years, and were willing to participate. Knowledge, attitudes, and behaviors were assessed using validated questionnaires and data on the severity of disease obtained from epidemiological forms. The collected data were then analyzed using chi-square statistical tests. 107 respondents had already filled in the questionnaires. The Chi-square test showed no significant association between knowledge (p 0.081), attitude (p 0.216), and behavior (p 0.136) of handwashing to the severity of COVID-19. A good level of knowledge, attitudes and behaviors about handwashing using soap did not adequately affect the severity of covid-19 patients. The good level of knowledge, attitude, and practice of HWUS were not significant enough to affect the severity of the COVID-19 disease.
ANTIBODY IgG LEVELS AND ADVERSE EVENTS FOLLOWING IMMUNIZATION AFTER THIRD DOSE OF MODERNA VACCINE IN HEALTHWORKERS AFTER TWO DOSES OF SINOVAC VACCINE Ade Tiur Rumondang; Utari Hartati Suryani; Debie Rizqoh; Mardhatillah Sariyanti; Besly Sinuhaji
JURNAL KEDOKTERAN DAN KESEHATAN Vol 10, No 2 (2023)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/JKK.V10I2.20872

Abstract

Health Care Workers (HCWs) are a top priority to receive the vaccination for Coronavirus Disease 2019 (Covid-19). After two doses of the Sinovac vaccine as the primary vaccine, protection against Covid-19 weakens over time, so a booster vaccination is considered to produce more antibodies. In addition, each vaccine is inseparable from Adverse Event Following Immunization (AEFI). This study compares antibody levels and AEFIs between two doses of the Sinovac vaccine with the Moderna booster. This research is an observational analytic study with a cross-sectional study design and the sampling method is random sampling with a total of 74 HCWs using a consecutive sampling method. Samples that had received two doses of the Sinovac vaccine or booster doses of the Moderna vaccine after two doses of the Sinovac vaccine were included. Samples that had been infected with Covid-19 before vaccination were excluded. IgG antibody levels were measured using Chemiluminescent Microparticle Immunoassay (CMIA), while vaccine type and AEFI were gathered via questionnaire. The severity of AEFIs is based on WHO classification. The data analysis used the Mann-Whitney and Chi-Square tests with a 95% Confidence Interval (CI) to determine the relationship between variables. Twenty-nine subjects received two doses of the Sinovac primary vaccine (38.2%), and forty-five received the Moderna booster vaccine (59.2%). In booster doses of the Moderna vaccine recipients, antibodies tended to be higher, and the most common AEFIs were systemic. There was a significant difference in IgG antibody levels between recipients of two doses of the Sinovac vaccine (median=2888.8 AU/mL) and booster Moderna vaccine recipients (median=18081.04 AU/mL) (p=0.000, p <0.05). There were significant differences in AEFI in the groups receiving two doses of the Sinovac vaccine and those receiving the booster vaccine (p=0.000, p<0.05). This study concludes that there is a significant correlation between administering the Covid-19 vaccine and post-vaccination IgG antibody levels and AEFI.
Spatial Distribution of COVID-19 Related to the Potential for Spreading Outbreaks and Vulnerability of a Region in Bengkulu Province on 2020 Naurah Shafa Putri Cahyangi; Dessy Triana; Liya Agustin Umar; Nikki Aldi Massardi; Utari Hartati Suryani; Riry Ambarsari
BENCOOLEN JOURNAL OF PHARMACY Vol. 2 No. 2 (2022): Oktober
Publisher : UNIB PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/bjp.v2i2.24359

Abstract

Coronavirus disease 2019 (COVID-19) was declared a pandemic on March 11, 2020, by the World Health Organization (WHO). The spread of COVID-19 increases with different conditions and situations in each region. Spatial distribution plays a role in identifying the vulnerability of an area. This study aimed to determine the differences in COVID-19 cases from one area to another in 10 regions in Bengkulu Province in 2020. This study is a descriptive study with an observational study through a cross-sectional approach using an epidemiological investigation form as a data source. Sampling was carried out from July to December 2020 and obtained from 3044 respondents who met the inclusion criteria. The total sampling technique did sampling. The relationship between the population density of an area and the severity of COVID-19 cases was statistically analyzed using the Spearman rank test. The results showed that areas with higher density levels, such as Bengkulu City, caused a wider spread of cases, causing the number of COVID-19 cases to increase compared to other areas with lower population densities in Bengkulu Province. There is no significant relationship between population density and the severity of COVID-19
The Correlation Between Adult Age Factors toward The Clinical Manifestation and The Severity Level of COVID-19 in Bengkulu Province in 2020 Begumratu VOCA; Dia Triyani Putri; Dessy Triana; Riry Ambarsari; Nikki Aldi Massardi; Utari Hartati Suryani
BENCOOLEN JOURNAL OF PHARMACY Vol. 2 No. 2 (2022): Oktober
Publisher : UNIB PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/bjp.v2i2.24362

Abstract

Coronavirus Disease-19 (COVID-19) is an acute respiratory disease in Wuhan, China, and was discovered discovered in 2019. The things that need to be considered in COVID-19 patients include their clinical manifestation and the severity level of COVID-19. The severity level of COVID-19 patients is associated with age. Each age has a different proportion of severity. The study aimed to determine the correlations among adult age with clinical manifestation and severity of COVID-19 in Bengkulu Province 2020. This study used an observational analytic study. The sample was 108 patients 19 - ≥65 years old and confirmed positive for COVID-19 in 2020. The assessment used the epidemiological investigation form and medical record from Dr. M.Yunus Hospital. At the same time, the severity level of COVID-19 was obtained from the measurement based on the COVID-19 Prevention and Control Guidelines by the Indonesian Ministry of Health. The results showed that the subjects in 19 – 23 years old mostly have asymptomatic severity, 24 – 64 years old mostly have mild severity, and ≥65 years old have moderate severity. It was concluded that there was a significant correlation between the severity of COVID-19 in Bengkulu Province in 2020.
The correlation between Children’s Age Factors toward the clinical manifestation and the severity level of COVID-19 in Bengkulu Province in 2020 Dia Triyani Putri; Begumratu VOCA; Diah Ayu Aguspa Dita; Dessy Triana; Riry Ambarsari; Utari Hartati Suryani
BENCOOLEN JOURNAL OF PHARMACY Vol. 2 No. 2 (2022): Oktober
Publisher : UNIB PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/bjp.v2i2.24363

Abstract

Coronavirus Disease 2019 (COVID-19) is a disease that can infect people of all ages. Symptoms can range from asymptomatic to severe in certain age groups. It can occur due to differences in the innate immune response, comorbidities and the function, distribution, maturation of the SARS-CoV-2 receptor. This study aimed to determine the correlation between children’s age factors toward the clinical manifestation and the severity level of COVID-19 in Bengkulu Province in 2020. An observational analytic study with cross-sectional design was used in this study. This study included 86 children aged 0-18 years old who were confirmed positive for COVID-19 and lived in Bengkulu Province from March to December 2020. The clinical manifestation was assessed using the COVID-19 epidemiological investigation form and medical records from M.Yunus Hospital. The degree of severity is determined using Ministry of Health of Indonesia’s Guidelines for COVID-19 Prevention and Control. The result showed that of the majority of children aged 0-1 years old, 5-11 years old, and 12-18 years old have asymptomatic severity illness. While children are between the ages of two and four, the majority of their illnesses are of a mild severity. There was no significant correlation between children age factors and the severity of COVID-19 in Bengkulu Province in 2020.
ANTIBODY IgG LEVELS AND ADVERSE EVENTS FOLLOWING IMMUNIZATION AFTER THIRD DOSE OF MODERNA VACCINE IN HEALTHWORKERS AFTER TWO DOSES OF SINOVAC VACCINE Ade Tiur Rumondang; Utari Hartati Suryani; Debie Rizqoh; Mardhatillah Sariyanti; Besly Sinuhaji
Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Vol. 10 No. 2 (2023): Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Univers
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/jkk.v10i2.345

Abstract

Health Care Workers (HCWs) are a top priority to receive the vaccination for Coronavirus Disease 2019 (Covid-19). After two doses of the Sinovac vaccine as the primary vaccine, protection against Covid-19 weakens over time, so a booster vaccination is considered to produce more antibodies. In addition, each vaccine is inseparable from Adverse Event Following Immunization (AEFI). This study compares antibody levels and AEFIs between two doses of the Sinovac vaccine with the Moderna booster. This research is an observational analytic study with a cross-sectional study design and the sampling method is random sampling with a total of 74 HCWs using a consecutive sampling method. Samples that had received two doses of the Sinovac vaccine or booster doses of the Moderna vaccine after two doses of the Sinovac vaccine were included. Samples that had been infected with Covid-19 before vaccination were excluded. IgG antibody levels were measured using Chemiluminescent Microparticle Immunoassay (CMIA), while vaccine type and AEFI were gathered via questionnaire. The severity of AEFIs is based on WHO classification. The data analysis used the Mann- Whitney and Chi-Square tests with a 95% Confidence Interval (CI) to determine the relationship between variables. Twenty-nine subjects received two doses of the Sinovac primary vaccine (38.2%), and forty-five received the Moderna booster vaccine (59.2%). In booster doses of the Moderna vaccine recipients, antibodies tended to be higher, and the most common AEFIs were systemic. There was a significant difference in IgG antibody levels between recipients of two doses of the Sinovac vaccine (median=2888.8 AU/mL) and booster Moderna vaccine recipients (median=18081.04 AU/mL) (p=0.000, p <0.05). There were significant differences in AEFI in the groups receiving two doses of the Sinovac vaccine and those receiving the booster vaccine (p=0.000, p<0.05). This study concludes that there is a significant correlation between administering the Covid-19 vaccine and post-vaccination IgG antibody levels and AEFI.
Novel Endophytic Bacteria Isolates from Andaliman (Zancthoxylum acanthopodium DC.) which Potentially Inhibit Escherichia coli and Staphylococcus aureus Rizqoh, Debie; Amelia, Aisyah; Kumala, Wulan Okta; Sipriyadi, Sipriyadi; Suryani, Utari Hartati; Sariyanti, Mardhatillah
Journal of Biomedicine and Translational Research Vol 10, No 1 (2024): April 2024
Publisher : Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jbtr.v10i1.21740

Abstract

Background: Irrational use of antibiotics has various side effects to resistance. Utilization of secondary metabolites of Andaliman plant endophytic bacteria (Z. acanthopodium DC) is an alternative known to act as an antibacterial to overcome this problem.Objective: This study aimed to determine the antimicrobial activity of the crude extract of Andaliman endophytic bacteria against Escherichia coli and Staphylococcus aureus.  Methods: This research is an experimental laboratory with qualitative data collection methods. The initial stages will be the isolation of endophytic bacteria from Andaliman, the antagonist test of Andaliman endophyte isolates against E. coli and S. aureus, and the extraction of endophytic bacterial isolates using ethyl acetate as solvent. An antagonistic test of bacterial isolate extract was performed using the disc diffusion method against pathogenic bacteria E. coli and S. aureus and observed by an inhibition zone. The final stage is the minimum inhibition test of endophytic isolates by dilution method on three potential endophytic isolates.Results: The results of the extraction of isolates EAA22, EAA28, EAB5, EAB6, and EAB7 Andaliman endophytic bacteria have inhibitory activity against S.aureus, and the results of the extraction of isolates EAB5, EAB6, EAA22 have inhibitory activity against E. coli.Conclusion: Endophyte bacteria isolates from Andaliman produce antibacterial compounds against E. coli and S. aureus. 
Counseling and Examination of Sharp Vision for Presbyopia Screening (Old Eyes) and Provision of Reading Glasses to the Elderly at Tresna Werdha Social Institution Bengkulu Province Suryani, Utari Hartati; Zainuddin, Zayadi
Jurnal Ilmiah Pengabdian Masyarakat Bidang Kesehatan (Abdigermas) Vol. 1 No. 2 (2023): Jurnal Ilmiah Pengabdian Masyarakat Bidang Kesehatan (Abdigermas)
Publisher : CV Media Inti Teknologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58723/abdigermas.v1i2.39

Abstract

According to World health Organization (WHO), the age group >60 years is categorized as elderly (elderly). Normally with age, a decrease in organ function will also occur naturally, one of which is in the organs of vision. So far, the community considers the decline in the function of vision in the elderly group as a normal thing to happen and does not require routine checks. Even though this condition will increase the risk of falling in the elderly and can cause other complex problems. The social institution is a place that aims to accommodate the elderly so that they can live their old age in a more quality manner, the Tresna Werdha Social Institution is one example and is under the guidance of the Social Service of Bengkulu Province which accommodates quite a number of elderly as its fostered citizens with various existing health problems, One of them is the problem of decreased visual acuity. In view of the conditions above, then community service needs to be done in this place, such as counseling, visual acuity checks and providing reading glasses to the elderly at the Tresna Werdha Bengkulu social institution. The purpose of this activity is to improve the quality of life for the elderly and reduce the risk of falling, especially for the assisted residents of the Tresna Werdha Social Institution, Bengkulu Province. The result of this activity was that 43 elderly people took part in educational activities, visual acuity checks and the provision of reading glasses which were carried out on October 2, 2022 by a community service team from the Faculty of Medicine and Health Sciences, University of Bengkulu. From this activity, it was found that 21 elderly people (49%) received assistance in the form of reading glasses while 22 (51%) other elderly people could not receive assistance in the form of reading glasses because they had cataracts.
PENGARUH USIA DAN JENIS KELAMIN TERHADAP KADAR IGG DAN KEJADIAN COVID-19 PASCAVAKSINASI PADA TENAGAESEHATAN KOTA BENGKULU Nabilah, Putri Syifa; Suryani, Utari Hartati; Massardi, Nikki Aldi; Rizqoh, Debie; Ambarsarie, Riry
Jurnal Kesehatan Tambusai Vol. 5 No. 1 (2024): MARET 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i1.24902

Abstract

Variabilitas respons antibodi terhadap vaksinasi COVID-19 dipengaruhi oleh faktor-faktor seperti usia dan jenis kelamin. Penelitian ini bertujuan untuk mengkaji dampak usia dan jenis kelamin terhadap kadar IgG serta kejadian COVID-19 pascavaksinasi. Dengan memperoleh pemahaman mendalam tentang hubungan ini, diharapkan dapat ditingkatkan strategi vaksinasi yang lebih efektif dan efisien bagi berbagai kelompok populasi. Penelitian ini adalah penelitian cross-sectional yang dilakukan selama periode Juli hingga Desember 2021, melibatkan partisipasi 60 tenaga kesehatan dari Rumah Sakit Harapan dan Doa (RSHD) di Kota Bengkulu. Data primer dikumpulkan dari responden ini dalam rangka mengidentifikasi hubungan antara usia, jenis kelamin, dan respons antibodi terhadap vaksinasi COVID-19. Pengambilan data kadar antibodi IgG dilakukan dengan teknik CMIA, sementara data usia, jenis kelamin, dan kejadian COVID-19 pascavaksinasi melalui kuesioner. Metode statistik yang diterapkan dalam penelitian ini mencakup serangkaian uji, seperti uji Kruskal-Wallis, uji Mann-Whitney, dan uji Chi-Square. Temuan penelitian menegaskan bahwa kelompok usia 40-55 tahun dan perempuan memiliki kadar IgG yang lebih tinggi, sedangkan proporsi kejadian COVID-19 pascavaksinasi lebih tinggi pada kelompok usia 20-29 tahun dan laki-laki. Hal ini menunjukkan pengaruh signifikan dari usia dan jenis kelamin terhadap respons antibodi dan kejadian COVID-19 pascavaksinasi. Kesimpulan ini memberikan wawasan penting bagi strategi vaksinasi yang lebih efektif dan cermat bagi berbagai kelompok populasi.
Co-Authors Ade Tiur Rumondang Ade Tiur Rumondang Ambarsarie, Riry Amelia, Aisyah Begumratu VOCA Besly Sinuhaji Besly Sinuhaji CINTYA NABILA PUTRI DEBIE RIZQOH Debie Rizqoh Dessy Triana Dessy Triana Dia Triyani Putri Diah Ayu Aguspa Dita HERNITA TAURUSTYA Kumala, Wulan Okta Liya Agustin Umar MARDHATILLAH SARIYANTI Mardhatillah Sariyanti Mardhatillah Sariyanti MEUTIA AGUSTIN Nabila Putri Firdalina Nabilah, Putri Syifa Naurah Shafa Putri Cahyangi Nikki Aldi Massardi NOVRIANTIKA LESTARI Putri, Dia Triyani Riry Ambarsari Riry Ambarsarie Sariyanti, Mardhatillah Sipriyadi SIPRIYADI SIPRIYADI Suryo Bantolo Voca, Begumratu Zainuddin, Zayadi Zayadi Zainuddin