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All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Journal of Biomedicine and Translational Research Mutiara Medika: Jurnal Kedokteran dan Kesehatan Dharma Raflesia : Jurnal Ilmiah Pengembangan dan Penerapan IPTEKS Jurnal Kesehatan Tambusai Indonesian Journal of Multidisciplinary Science Jurnal Ilmiah Pengabdian Masyarakat Bidang Kesehatan Bencoolen Journal of Pharmacy Biodiversitas Journal of Biological Diversity
Suryani, Utari Hartati
Departemen Mikrobiologi Fakultas Kedokteran Dan Ilmu Kesehatan Universitas Bengkulu
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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The Relationship Between Age and Clinical Manifestations and COVID-19 Severity in Bengkulu in 2020 Suryani, Utari Hartati; Triana, Dessy; Ambarsarie, Riry; Zainuddin, Zayadi; Massardi, Nikki Aldi; Voca, Begumratu; Putri, Dia Triyani
Indonesian Journal of Multidisciplinary Science Vol. 2 No. 12 (2023): Indonesian Journal of Multidisciplinary Science
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/ijoms.v2i12.643

Abstract

The infectious disease COVID-19 caused by the SARS-CoV-2 virus can infect all age groups. The symptoms that arise can vary from no symptoms to severe and critical symptoms. Differences in clinical symptoms can occur due to differences in the distribution, maturation and function of the SARS-CoV-2 virus receptors. These clinical symptoms will determine the severity of COVID-19. This study aims to analyze the relationship between age and clinical symptoms and the severity of COVID-19 in Bengkulu Province in 2020. This study used an observational analytic study with a cross-sectional design. Samples were taken using a consecutive sampling technique and a total of 109 subjects were obtained who were COVID-19 patients in Bengkulu Province from March to December 2020. Assessment of clinical symptoms used COVID-19 epidemiological investigations. The degree of severity is determined based on the Guidelines for the Prevention and Control of COVID-19 by the Ministry of Health of the Republic of Indonesia. The relationship between the two variables was analyzed using the Spearman Rank test. The results of this study indicate that there is a significant relationship between the age factor of COVID-19 patients in determining the severity of COVID-19 (p=0.000; p <0.05).
Exploring the antibacterial activity of endophytic bacteria from Andaliman (Zanthoxylum acanthopodium DC.) against Bacillus subtilis DEBIE RIZQOH; SIPRIYADI SIPRIYADI; UTARI HARTATI SURYANI; CINTYA NABILA PUTRI; MEUTIA AGUSTIN; HERNITA TAURUSTYA; NOVRIANTIKA LESTARI; MARDHATILLAH SARIYANTI
Biodiversitas Journal of Biological Diversity Vol. 25 No. 2 (2024)
Publisher : Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/biodiv/d250229

Abstract

Abstract. Rizqoh D, Sipriyadi, Suryani UH, Putri CN, Agustin M, Taurustya H, Lestari N, Sariyanti M. 2024. Exploring the antibacterial activity of endophytic bacteria from Andaliman (Zanthoxylum acanthopodium DC.) against Bacillus subtilis. Biodiversitas 25: 700-707. Infectious diseases are still one of the global health problems. Increasing antibiotic resistance against several pathogenic microbes causes antibiotics to be less effective in treating infectious diseases. One pathogenic bacteria that causes infection is Bacillus subtilis, which causes bacteremia, septicemia, and endocarditis. Therefore, searching for new alternative antibiotics is urgently needed to overcome bacterial resistance. Andaliman (Zanthoxylum acanthopodium DC.) extract produces antimicrobial bioactive compounds. Thus, this study aims to explore endophytic bacteria from Z. acanthopodium and determine their antibacterial activity against Bacillus subtilis. This study used a qualitative experimental method, namely isolation of endophytic bacteria, characterization of endophytic bacteria colonies and cells, antagonistic test against B. subtilis, extraction of compounds from endophytic bacteria, and determine Minimum Inhibitory Concentration (MIC) of crude extract of endophytic bacteria against B. subtilis. This study showed that 16 endophytic isolates from Z. acanthopodium could inhibit the growth of B. subtilis, and potential isolates were EA7 and EA26, which have Minimum Inhibitory Concentration (MIC) at 40%, and EB6 at 80%.
Co-Authors Ade Tiur Rumondang Ade Tiur Rumondang Ambarsarie, Riry Amelia, Aisyah Begumratu VOCA Besly Sinuhaji Besly Sinuhaji CINTYA NABILA PUTRI DEBIE RIZQOH Debie Rizqoh Dessy Triana Dessy Triana Dia Triyani Putri Diah Ayu Aguspa Dita HERNITA TAURUSTYA Kumala, Wulan Okta Liya Agustin Umar MARDHATILLAH SARIYANTI Mardhatillah Sariyanti Mardhatillah Sariyanti MEUTIA AGUSTIN Nabila Putri Firdalina Nabilah, Putri Syifa Naurah Shafa Putri Cahyangi Nikki Aldi Massardi NOVRIANTIKA LESTARI Putri, Dia Triyani Riry Ambarsari Riry Ambarsarie Sariyanti, Mardhatillah Sipriyadi SIPRIYADI SIPRIYADI Suryo Bantolo Voca, Begumratu Zainuddin, Zayadi Zayadi Zainuddin