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All Journal Narra J Media Dermato-Venereologica Indonesiana Journal of General Procedural Dermatology and Venereology Indonesia Indonesian Journal of Case Reports
Pradistha, Aldilla
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Overlapping Neurological Insults: Case Report of Herpes Zoster in Multibacillary Leprosy with Reversal Reaction Earlia, Nanda; Pradistha, Aldilla
Indonesian Journal of Case Reports Vol. 3 No. 2 (2025): December 2025
Publisher : Heca Sentra Analitika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60084/ijcr.v3i2.335

Abstract

Herpes zoster (HZ) is a reactivation of the varicella zoster virus (VZV). Low immunity, whether due to advanced age, immunosuppressants such as corticosteroids, or chronic infectious conditions such as Morbus Hansen (MH), is the primary predisposing factor for VZV reactivation. A 48-year-old man, previously diagnosed with Morbus Hansen, presented with a painful, burning, erythematous rash that began 5 days before presentation, followed by the development of grouped, fluid-filled blisters on the left waist, some of which ruptured and formed crusts. In the TZANK test, multinucleated giant cells were identified. The patient was given acyclovir, gabapentin, and mupirocin ointment. Leprosy therapy was continued, but corticosteroids were temporarily discontinued until the HZ lesions improved. After 1 week, improvements were observed in the lesions. Adequate therapy is crucial to prevent severe complications in immunocompromised patients. Clinicians should be aware of the potential for this dual disorder, particularly in immunocompromised patients, to promptly identify and manage this condition, thereby minimizing nerve damage, improving patient outcomes, and preventing disability. This case also underscores the need for careful neurological assessment and tailored strategies and therapies in patients with complex infectious neuropathies.
Co-Authors . Zulfan Abdurrazaq Abdurrazaq, Abdurrazaq Adriman, Zikri Alghani, Fajri asrizal, cynthia wahyu Athira, Athira Azzahra, Shelda Syifa Badiri, Istanul Budini, Sulamsih S. Dinillah, Teuku Muhammad Muizzy Earlia, Nanda Farsa, Bianda Sabrina Handriani, Risna hidayati, Arie Ibrahim, Teuku Maulana Malik Ikram, Tubagus Pasca Faiz Ismida, Fitri Dewi Junaidi, Fachrul Kamarlis, Reno K. Liana, Mahda Rizki Maulida, Mimi Maulidina, Rizka Yuliani Menul Ayu Umborowati, Menul Ayu Mikyal Bulqiah, Mikyal Murtadha, Raihan NUR FAJRINA Rahmatillah, Muhammad Zahrul Ramadhani, Cut Sukma Razaq, Abdur Reno Keumalazia Kamarlis Salim, Fitria Sari, Ninda Sulamsih Sri Budini, Sulamsih Sri Tasrif, Aqil Yuniawan Thahir, Tanziela Vella, Vella Vemulen, Dara Avinda Wahyu Lestari Wisesa, Wizurai Yoo, Soo-Ji Zuhra, Sofi Alfia