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Perbedaan Tekanan Darah Sistolik dan Diastolik Pada Kelompok Lanjut Usia Dengan Insomnia Djung Lilya Wati; Meilani Kumala; Zita Atzmardina; Fernando Nathaniel; Dean Ascha Wijaya
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 1 No. 3 (2023): Juli : Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v1i3.2060

Insomnia is the most common sleep disorder experienced by the elderly, which has a significant negative effect on morbidity and mortality in the elderly group. A study from the Penn State Adult Cohort found that people who are sleep deprived with objectively short sleep duration have a higher risk of developing hypertension. This cross-sectional study aims to determine differences in systolic and diastolic blood pressure in the elderly group (³60 years) with insomnia which were selected consecutively at the Tarumanagara University COVID-19 Vaccine Center for the period March – April 2021. The Insomnia Severity Index (ISI) questionnaire was used to evaluate the severity of insomnia. Blood pressure is measured with a digital tensimeter according to standard procedures. Statistical analysis using the Mann Whitney test. Of the 119 respondents, the average age was 69.84 years and 58% of the respondents were women. The mean systolic blood pressure was 150.18 and the average diastolic blood pressure was 83.23. From all respondents, it was found that 17.6% of respondents experienced insomnia. The results of the Mann Whitney statistical test explained that there was no difference in the mean systolic and diastolic blood pressure in the group with insomnia and without insomnia (p-value > 0.05). Further clinical studies revealed that the group of elderly who had insomnia tended to have higher blood pressure than the group of elderly who did not experience insomnia (SBP: 160 vs 151; DBP: 85 vs 84). Dealing with insomnia can be an effort to lower blood pressure.

Perbedaan Indeks Massa Tubuh pada Ibu Hamil dengan Preeklamsi Ringan, Berat, dan Eklamsi di Rumah Sakit Umum Daerah (RSUD) Ciawi Syamsu Rijal; Fernando Nathaniel; Dean Ascha Wijaya; Joshua Kurniawan
Detector: Jurnal Inovasi Riset Ilmu Kesehatan Vol. 1 No. 3 (2023): Agustus : Jurnal Inovasi Riset Ilmu Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/detector.v1i3.2182

Background: Preclampsia is a one of complication in pregnancy characterised by systolic blood pressure ≥140 mmHg and/or diastolic blood pressure ≥90 mmHg and proteinuria (≥300mg/24hours in urine; protein/creatinine ≥0.3; dipstick protein +1; and/or with additional symptoms. Eclampsia is a severe form of preeclampsia where the mother experiences seizures and/or coma. There are various risk factors for preeclampsia and eclampsia, one of which is the mother's body mass index (BMI). Excessive maternal weight before pregnancy, as well as excessive weight gain during pregnancy are at risk for preeclampsia. Methods: This study used medical records from the Ciawi General Hospital in 2020, and cross-sectional observational study was carried out. Pregnant women with eclampsia and preeclampsia were the study's population. This study used total sampling as its sampling method, and body mass index measurements were made using information from medical records. The Kruskall Wallis alternative test was utilized in place of the One Way Anova as the hypothesis test in this investigation. In this investigation, a 5% level of significance is expected. Results: This study involved 190 respondents who met the inclusion criteria. The statistical test results showed no significant difference in mean body mass index between the eclampsia, severe preeclampsia, and mild preeclampsia groups (P-value: 0.688). This difference is expected due to the small number of samples and/or the high variability of the samples. Conclusion: Based on the results of the study, there was no significant association between body mass index and mild, severe, and eclampsia. Further research should be conducted and developed for prevention and lifestyle intervention in preeclampsia.

Cross-Sectional Study of Efficacy, Effectiveness, and Safety of Combination Creams (Tretinoin 0.05%, Clindamycin 3%, and Dexamethasone 0.05%) Anti-Acne – An Online Study Tan, Sukmawati Tansil; Yohanes Firmansyah; Hendsun Hendsun; Alicia Sarijuwita; William Gilbert Satyanegara; Joshua Kurniawan; Dean Ascha Wijaya
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 4 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i4.956

Background: Acne vulgaris is a common skin condition that causes blackheads, whiteheads, and pimples. It is caused by a number of things, like too much oil, clogged pores, and inflammation. Topical combination creams are an alternative treatment for acne. They can help reduce inflammation, kill bacteria that cause acne, and stop the skin from making too much oil. Topical combination creams like retinoids, antibiotics, and steroids are all mixed together in a single cream or gel. This study talks about the effectiveness and side effects of using combination creams (tretinoin 0.05%, clindamycin 3%, and dexamethasone 0.05%) to treat acne in the short and long term (local and systemic). Methods: This study is a survey that was done at the Sukma clinic with data from 2022 patients who were diagnosed with acne vulgaris. The survey was done on Google Forms, which is a website. In this study, different factors were looked at, such as demographics, efficacy (like reducing acne severity, making the skin brighter, getting rid of blackheads on the face, getting rid of acne scars, improving skin texture, hiding scars, minimizing facial pores, getting rid of wrinkles and dark spots), local adverse events (like burning, itching, stinging, eruptive papules, hypopigmentation, hyperpigmentation, erythema, scaling, and other), and systemic adverse events. Results: The results of this study show that a combination of tretinoin 0.05%, clindamycin 3%, and dexamethasone 0.05% is very effective and has minimal side effects. Local symptoms only show up during the first week of taking the drug (the "sensitization phase"), and then they tend to get less common over time. The only exceptions are hyperpigmentation and hypopigmentation, which show up later because they are caused by healing acne lesions. Conclusion: There was no direct link between the use of anti-acne combination cream drugs and the number of systemic side effects. This is because the patient had often had this happen before (constipation, GERD, and others).

Cross-Sectional Study of Efficacy, Effectiveness, and Safety of Combination Creams (Tretinoin 0.05%, Clindamycin 3%, and Dexamethasone 0.05%) Anti-Acne – An Online Study Tan, Sukmawati Tansil; Yohanes Firmansyah; Hendsun Hendsun; Alicia Sarijuwita; William Gilbert Satyanegara; Joshua Kurniawan; Dean Ascha Wijaya
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 4 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i4.956

Background: Acne vulgaris is a common skin condition that causes blackheads, whiteheads, and pimples. It is caused by a number of things, like too much oil, clogged pores, and inflammation. Topical combination creams are an alternative treatment for acne. They can help reduce inflammation, kill bacteria that cause acne, and stop the skin from making too much oil. Topical combination creams like retinoids, antibiotics, and steroids are all mixed together in a single cream or gel. This study talks about the effectiveness and side effects of using combination creams (tretinoin 0.05%, clindamycin 3%, and dexamethasone 0.05%) to treat acne in the short and long term (local and systemic). Methods: This study is a survey that was done at the Sukma clinic with data from 2022 patients who were diagnosed with acne vulgaris. The survey was done on Google Forms, which is a website. In this study, different factors were looked at, such as demographics, efficacy (like reducing acne severity, making the skin brighter, getting rid of blackheads on the face, getting rid of acne scars, improving skin texture, hiding scars, minimizing facial pores, getting rid of wrinkles and dark spots), local adverse events (like burning, itching, stinging, eruptive papules, hypopigmentation, hyperpigmentation, erythema, scaling, and other), and systemic adverse events. Results: The results of this study show that a combination of tretinoin 0.05%, clindamycin 3%, and dexamethasone 0.05% is very effective and has minimal side effects. Local symptoms only show up during the first week of taking the drug (the "sensitization phase"), and then they tend to get less common over time. The only exceptions are hyperpigmentation and hypopigmentation, which show up later because they are caused by healing acne lesions. Conclusion: There was no direct link between the use of anti-acne combination cream drugs and the number of systemic side effects. This is because the patient had often had this happen before (constipation, GERD, and others).

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