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SKRINING FITOKIMIA DAN FORMULASI SEDIAAN KRIM EKSTRAK ETANOL DAUN PUCUK MERAH (Syzygium myrtifolium, Walp.) ASAL DESA RUMBERU Cut Bidara Panita Umar; Amelia Niwele; Maria Surlia
Journal of Innovation Research and Knowledge Vol. 4 No. 9: Februari 2025
Publisher : Bajang Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53625/jirk.v4i9.9694

Abstract

Pucuk merah (Syzygium myrtifolium, Walp.) merupakan sejenis tanaman perdu yang memiliki aktivitas antibakteri karena mengandung senyawa metabolit sekunder antara lain alkaloid, flavonoid, saponin, tannin dan minyak atsiri, sehingga dapat dibuat dalam bentuk sediaan farmasi yaitu krim untuk mengatasi infeksi kulit. Penelitian ini bertujuan untuk mengetahui kandungan metabolit sekunder dan memformulasikan sediaan krim dari ekstrak etanol daun pucuk merah (Syzygium myrtifolium, Walp.). Metode penelitian yang digunakan yaitu eksperimental laboratorium dengan pembuatan sediaan krim menggunakan 3 variasi konsentrasi ekstrak etanol daun pucuk merah (Syzygium myrtifolium, Walp.) yaitu FI 2%, FII 4% dan FII 8%. Hasil penelitian sediaan krim ekstrak etanol daun pucuk merah (Syzygium myrtifolium, Walp.) menunjukan sediaan krim yang baik dan stabil selama penyimpanan yaitu uji organoleptik untuk FI berwarna kuning pucat, FII berwarna cokelat muda dan FIII berwarna cokelat dengan tekstur krim semi padat dan wangi lavender, nilai pH krim antara 7,5 - 8, uji homogenitas ketiga formulasi menunjukan hasil yang homogen, dengan uji tipe emulsi menunjukan sediaan krim tipe emulsi minyak dalam air (O/W), uji daya lekat krim berkisar antara 5-6 detik dan uji iritasi dari ketiga formulasi tidak menimbulkan reaksi iritasi pada probandus yang diujikan.
ANALISIS PERBEDAAN KADAR β-KAROTEN PADA UBI JALAR KUNING (Ipomoea batatas L.) MENTAH DAN REBUS DENGAN MENGGUNAKAN METODE SPEKTROFOTOMETRI UV-VIS Cut Bidara Panita Umar; Jamila F Kabakoran; Dewi Sukma Hukom
Jurnal Ilmiah Kedokteran dan Kesehatan Vol. 1 No. 2 (2022): Mei: Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v1i2.1161

Abstract

Sweet potato is a good food ingredient, because of its starch which has a very rich nutritional content, including high carbohydrates. Therefore, in some areas sweet potato is also used as a staple food. It also contains protein, vitamin C and is rich in vitamin A (β-carotene). β-carotene in yellow sweet potato (Ipomoea batatas L.) can function to meet the needs of vitamin A and as an antioxidant in reducing the effects of free radicals. The purpose of this study was to determine the differences in β-carotene levels in raw and boiled yellow sweet potato (Ipomoea batatas L.) using the UV-Vis spectrophotometry method. Samples of yellow sweet potato were extracted by using maceration method with 95% ethanol solvent. Then a quantitative analysis was performed using the UV-Vis spectrophotometry method at a wavelength of 450 nm and a linear regression equation was obtained y = 0.0237x + 0.395 and a correlation coefficient (r) of 0.9931 and an average level of β-carotene in raw yellow sweet potato was obtained of 1278 .23 mg/kg and boiled yellow sweet potato of 413.90 mg/kg. So from this study it can be concluded that the levels of β-carotene in raw yellow sweet potatoes are greater than boiled yellow sweet potatoes because some boiled yellow sweet potatoes have been damaged due to heat or dissolved / lost to water.
AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL KUMIS KUCING ( Orthosipon Aristatus )TERHADAP PERTUMBUHAN BAKTERI Staphyloccocus aureus DENGAN MENGGUNAKAN METODE DIFUSI Aulia Debby Pelu; Cut Bidara Panita Umar; Nadhira Fahreza Patimahu
Jurnal Ilmiah Kedokteran dan Kesehatan Vol. 1 No. 2 (2022): Mei: Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v1i2.1176

Abstract

Cat's whiskers leaf plant (Ortosiphon aristatues.) is one of the plants that is efficacious as a medicinal plant. The part of the cat's whiskers leaf plant is used, namely the leaves that contain saponin compounds, flavonoids, alkaloids and tannins. The purpose of this study was to determine the most effective inhibition produced by the ethanol extract of the leaves of the cat's whiskers (Ortosiphon aristatues.) against the growth of Staphyloccocus aureus bacteria. The benefit of this research is to increase knowledge about the antimicrobial potential of ethanol extract of cat whiskers (Ortosiphon arietatus) leaves against the growth of Staphyloccocus aureus bacteria. This research method uses the diffusion method for wells. The sample used was cat whiskers leaf extract with pure strain of Staphyloccocus aureus. Treatment with cat whiskers leaf extract, the results of the test of the inhibitory activity of the cat whiskers leaf extract showed an average difference at a concentration of 65% with a diameter of 22 mm, a concentration of 70% with a diameter of 25 mm, and a concentration of 75% with a diameter of 30 mm. Ethanol extract of cat whiskers leaves with a concentration of 65%, 70%, and 75% effectiveness in inhibiting the growth of Staphylococcus aureus bacteria. Based on observations, it was shown that the ethanolic extract of Kumis Kucing leaves gave the most effective inhibitory concentration at a concentration of 75% against Staphyloccocus aureus bacteria. with a diameter of 30 mm