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All Journal Nusantara Hasana Journal Jurnal Pengabdian Ilmu Kesehatan Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Ardhi: Jurnal Pengabdian dalam Negri
Sri Hainil
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Agriculture, Biological Sciences & Forestry Humanities Computer Science & IT Economics, Econometrics & Finance Education Engineering Health Professions Nursing Public Health

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AKTIVITAS ANTIJAMUR FRAKSI DAUN MANGKOKAN (Polyscias scutellaria) TERHADAP JAMUR TRICHOPHYTON RUBRUM Rury Trisa Utami; Sri Hainil; Hesti Marliza; Hafizah, Hafizah
Nusantara Hasana Journal Vol. 5 No. 10 (2026): Nusantara Hasana Journal, March 2026
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i10.1922

Abstract

One of the natural ingredients that are often used as medicinal plants is mangkokan leaves (Polyscias scutellaria). Mangkokan leaves have the potential as an antifungal. Trichophyton rubrum is a fungus that infects human skin. The purpose of this study was to determine the antifungal activity of mangkokan leaf fractions (Polyscias scutellaria) against Trichophyton rubrum fungi. Fractionation was carried out using the liquid-liquid method using n-hexane, ethyl acetate and ethanol-water solvents. Testing was carried out using the disc paper diffusion method. The concentration of the fraction extract used was 600 µg/disk. The results showed that of the three fractions of mangkokan leaves (Polyscias scutellaria), the ethyl acetate fraction and the ethanol-water fraction had antifungal activity, while the n-hexane fraction did not have antifungal activity. Based on the research that has been done, it can be concluded that the fraction of mangkokan leaves (Polyscias scutellaria) has antifungal activity against Trichophyton rubrum fungus. Of the three fractions tested, the ethanol-water fraction has the highest antifungal activity with an average inhibition zone of 11.3 mm against Trichophyton rubrum fungus, the ethyl acetate fraction has an inhibition zone with an average of 4.5 mm while the n-hexane fraction has no inhibition zone. The three fractions have been compared with ketoconazole 30 µg/disk as a positive control and 10% DMSO as a negative control. From the comparison of fraction measurements against the positive control, the ethanol-water fraction is included in the strong category and the ethyl acetate fraction is included in the weak category.
Co-Authors Andi Bunga Dahlia Aprilya Sri Rachmayanti Aprilya Sri Rhacmayanti Aria Juanda Cindy Octavia Delladari Mayefis Desy Maniarti Gusmali Faziyana Faziyana Ghiffari, Habibie Deswilyaz Habibie Deswilyaz Hafizah Hafizah Henny Rachdiati Hesti Marliza Merry Ardini Nanda Siska Nurliyasman Nurliyasman Nurul Asiqin Oktasari Oktasari Rastria Meilanda Reny Haryani Rury Trisa Utami Selawati Selawati Senny Mey Pratiwi Shinta Sari Dewi Sri Budiasih Sri Rahayu Melpa Sari Suci Fitriani Sammulia Suhaera Suhaera Suhaera Yunisa Friscia Yusri