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ANTI-INFLAMMATORY EFFECT OF LEAF ETHANOL EXTRACT OF CAT'S KUMIZE (Orthosiphon stamineus Benth) IN MALE WHITE RATS OF WISTAR STRAINS Meyana Marbun; Dian Permata Nasution; Beta Hanindiya; Mustaruddin; Yulia Delfahedah; Arsiaty
International Conference on Health Science, Green Economics, Educational Review and Technology Vol. 3 (2021): International Conference on Health Science, Green Economics, Educational Review and T
Publisher : Universitas Efarina

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54443/ihert.v3i.244

Abstract

The cat's whiskers plant is empirically used by the community for the treatment of gout and rheumatism. This research was conducted with the aim of knowing the anti-inflammatory power of cat's kumis (Orthosihon stamineus Benth) leaf extract. This study was a quasi-experimental study with a one-way completely randomized design. Kumis Kucing leaf extract was extracted using 70% ethanol. A total of 25 male wistar rats aged 2-3 months, weighing 150-200g were divided into 5 groups. Each group was treated orally with distilled water (negative control), diclofenac sodium 2.25 mg/kg BW (positive control). Kumis leaf ethanol extract tested at doses of 123, 245 and 490 mg/kgBB. Treatment 1 hour before the feet of rats were inflamed with 1% sublantar carrageenin. Measurements of the rat's foot volume were carried out every 0.5 hours for 6.5 hours. The obtained average edema volume curve is used to calculate AUC (Area Under The Curve) and the obtained AUC is used to calculate DAI (Anti-Inflammatory Power). The AUC and DAI data were tested statistically with one way Anava and followed by LSD with a 95% confidence level. The results showed that the ethanol extract of Kumis Kucing leaves had an anti-inflammatory effect on male white rats of the Wistar strain. Kumis Kucing ethanol extract at doses of 123, 245 and 490 mg/kg BW yielded 33.11%; 52.64% and 64.12% respectively. The results showed that the ethanol extract of Kumis Kucing leaves had an anti-inflammatory effect on male white rats of the Wistar strain. Kumis Kucing ethanol extract at doses of 123, 245 and 490 mg/kg BW yielded percent anti-inflammatory properties of 33.11%; 52.64% and 64.12%, respectively. The results showed that the ethanol extract of Kumis Kucing leaves had an anti-inflammatory effect on male white rats of the Wistar strain. Kumis Kucing ethanol extract at doses of 123, 245 and 490 mg/kg BW yielded percent anti-inflammatory properties of 33.11%; 52.64% and 64.12%, respectively.
UTILIZATION OF TURMERIC RHIZOME EXTRACT (Curcuma domestica v.) AS A DYE IN HAIR DYE PREPARATIONS Meyana Marbun; Arsiaty Sumule; Yulia Delfahedah; Muharti Sanjaya; Dilla Sastia Mara
International Conference on Health Science, Green Economics, Educational Review and Technology Vol. 4 (2022): International Conference on Health Science, Green Economics, Educational Review and T
Publisher : Universitas Efarina

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54443/ihert.v4i.246

Abstract

Hair coloring preparations are cosmetic preparations used in hair cosmetology to color hair, either to restore the original hair color or another color. Turmeric rhizome contains alkaloids, flavanoid tannins and essential oils. The purpose of this study was to determine the chemical compounds contained in turmeric rhizome, to make turmeric rhizome change the color of gray hair. Hair dye preparation is made with a formula consisting of a concentration of turmeric extract rhizome, namely 20%. This research method is experimental by using maceration method. Physical evaluation carried out included homogeneity test, irritation test, color stability test against sun exposure, color stability test against washing. The results of this study indicate that turmeric rhizome extract can affect the color of the gray hair obtained. The stability test against washing can last for 5 times washing, the stability test against sunlight shows that the hair turns darker than before.
Analisis Gaya Kepemimpinan Terhadap Motivasi Kinerja Pegawai di Puskesmas Tigarunggu Pada Tahun 2024 Zendrato, Ferawati; Jumadiah Wardati; Toberni S. Situmorang; Meyana Marbun; Marolop. P. Napitu
Excellent Midwifery Journal Vol. 7 No. 1 (2024): Vol. 7 No. 1 (2024) EDISI APRIL
Publisher : STIKes Mitra Husada Medan

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Abstract

Suatu organisasi harus memiliki seorang pemimpin yang mampu mengarahkan dan membimbing pegawai dalam organisasi . hubungan anrata gaya kepemimpinan terhadap motivasi kinerja pegawai yaitu dimana apabila semakin tinggi motivasi kinerja seorang pegawai dalam bekerja maka kinerja yang dihasilkan juga akan semakin efektif dan kompeten dalam bidang kerja nya. Penelitian ini bertujuan untuk mengetahui analisis gaya kepemimpinan terhadap motivasi kinerja pegawai di puskesmas Tigarunggu pada tahun 2024. Dengan jumlah sample 30 orang. Alat pengumpulan data yang di gunakan adalah kuesioner dan analisis data dilakukan secata univariat menggunakan pengolahan data. Hasil analisis uji chi-square dapat diperoleh gaya kepemimpinan memiliki hubungan terhadap terhadap Motivasi kinerja pegawai Puskesmas Tigarunggu pada tahun 2024. Berdasarkan uji SPSS yang telah dilakukan oleh peneliti, hubungan antara Gaya kepemimpinan terhadap Motivasi kinerja pegawai di Puskesmas Tigarunggu pada Tahun 2024, dilihat dari uji statistic yang digunakan dengan tes chi-square di peroleh nilai p=0,00 atau (p<0,05) yang berarti H1 diterima dan H0 di tolak yang menyatakan bahwa ada hubungan signifikan antara Gaya Kepemimpinan dengan Motivasi Kinerja Pegawai di Puskesmas Tigarunggu pada Tahun 2024. Berdasarkan uji data yang telah dilakukan di peroleh melalui hasil nilai yang signifikan sebesar p=0,03 maka di simpulkan bahwa ada Hubungan yang signifikan antara Gaya kepemimpinan Terhadap Motivasi Kinerja Pegawai di Puskesmas Tigarunggu pada Tahun 2024.
PERBANDINGAN EFIKASI KOMBINASI ACE-i + CCB DAN ACE-i + DIURETIK TERHADAP PENURUNAN TEKANAN DARAH PADA PASIEN STROKE ISKEMIK DI RAWAT JALAN RUMAH SAKIT EFARINA ETAHAM PEMATANGSIANTAR Octavian Ashindo Nababan; Meyana Marbun; Hekdin Marsius Sipayung; Yunda Pita Sari Simbolon
Medic Nutricia : Jurnal Ilmu Kesehatan Vol. 9 No. 2 (2024): Medic Nutricia : Jurnal Ilmu Kesehatan
Publisher : Cahaya Ilmu Bangsa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5455/nutricia.v9i2.6885

Abstract

Hipertensi adalah suatu kondisi peningkatan tekanan darah di atas normal yang dapat menyebabkan peningkatan morbiditas dan mortalitas. Pengobatan hipertensi merupakan pencegahan efektif untuk serangan stroke yang pertama, pengobatan hipertensi pada pasien yang pernah menderita TIA atau stroke ternyata juga mengurangi secara signifikan kemungkinan terjadinya stroke berulang (prevensi sekunder). Penelitian ini bertujuan untuk mengetahui Untuk mengetahui perbandingan efikasi penggunaan kombinasi ARB + ACE-i dan ACE-i + Diuretik pada pasien hipertensi dengan stroke di Rumah Sakit Efarina Etaham Pematangsiantar. Pada penelitian ini menggunakan metode retrospektif menggunakan data rekam medis pasien rawat jalan yang menggunakan terapi kombinasi ARB + ACE-i dan ACE-i + Diuretik. Hasil penelitian menunjukkan pada pasien dengan terapi kombinasi CCB + ACE-I dapat menurunkan tekanan darah sistole -15,75 dan diastole sebesar -4,60, sedangkan terapi kombinasi ACE-i + DIURETIK menurunkan tekanan darah sistole sebesar -13,15 dan diastole sebesar -8,45. Tidak terdapat perbedaan efikasi antara terapi kombinasi CCB + ACE-i dengan ACE-i + DIURETIK terhadap penurunan tekanan darah pada pasien stroke dirawat jalan RS Efarina Etaham Pematangsiantar tahun 2023.
Tingkat Kepolaran Pelataut Pada Aktivitas Antibakteri Ekstrak Daun Mayana (Coleus Atropurpureus [L] Benth ) Meyana Marbun; Ummi Umayyah; Boas Nicoyono Pasaribu; Indri Nurhabibah
JFARM - Jurnal Farmasi Vol. 2 No. 2 (2024)
Publisher : Yayasan Rahmatan Fiddunya Wal Akhirah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58794/jfarm.v2i2.1053

Abstract

Telah dilakukan penelitian tentang Uji aktivitas antibakteri ekstrak daun mayana (Coleus atropurpureus [L] Benth.) dari beberapa tingkat kepolaran pelarut. Tujuan penelitian ini adalah mengetahui berapa daya hambat ekstrak daun mayana terhadap bakteri gram positif (Streptococcus mutans) dan bakteri gram negatif (Shigella dysenteriae) berdasarkan tingkat kepolaran pelarut. Metode ekstraksi yang digunakan dalam penelitian ini yaitu metode maserasi dengan 4 tingkat polaritas pelarut yang dimulai dari pelarut non polar (n-heksan), diikuti dengan pelarut semipolar (etil asetat dan kloroform) dan pelarut polar (etanol). Pengujian aktivitas antibakteri dilakukan dengan uji metode sumur difusi, dan parameter yang diamati adalah diameter daya hambat. Hasil penelitian menunjukan bahwa ekstrak n-heksan memberikan daya hambat tertinggi pada bakteri gram negatif (Shigella dysenteriae) dan ektrak n-heksan pada bakteri gram positif (Streptococcus mutans) berturut-turut adalah 22.81 mm dan 20.99 mm. Jadi, ekstrak daun mayana dapat menghambat bakteri Shigella dysenteriae dan Streptococcus mutans dengan kategori yang sangat kuat.  
ANALISIS TINGKAT KEPUASAN PASIEN RAWAT JALAN PESERTA BPJS KESEHATAN TERHADAP PELAYANAN KEFARMASIAN DI INSTALASI FARMASI RUMAH SAKIT EFARINA ETAHAM KOTA PEMATANGSIANTAR TAHUN 2024 Dilla Sastri Mara; Meyana Marbun; Arsiaty Sumule; Juliana Siboro
ZAHRA: JOURNAL OF HEALTH AND MEDICAL RESEARCH Vol. 4 No. 4 (2024): OKTOBER
Publisher : CV. ADIBA ADISHA AMIRA

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Abstract

Quality of service is the level of outpatient satisfaction with pharmaceutical service from a pharmacy installation of Efarina Etaham Hospital Pematangsiantar City isone of the service provided by the health insurance administering agency (BPJS). It is necessary to obtain input on the extent of patiemt satisfaction with the service provided, especially in the pharmaceutical service section. This research is a descriptive analityc study with purposive sampling method, the research starts from the collection of data 02 july to 03 august 2024 to report the results of the research. The study was conducted everyday with a sample of 80 people and used a questionnaire as a measurement tool in which respondents were asked too fill out the questionnaire were outpatients BPJS health participants. The data that has been collected is analyzed descriptively using SPSS software that is addressed through the parameters of the level of satisfaction that is reliability, responsibility, assurance, empathy, and tangible.The level outpatient satisfaction of BPJS health in pharmacy outpatient with pharmaceutical services at Efarina Etaham Hospital, Pematangsiantar city, was obtained by the percentage of reliability 90,46% (very satisfied), responsiviness 98,16% (very satisfied), assurance 93,95% (very satisfied), empathy 99,79% (very satisfied), anf tangilible 104,49% (very satisfied), with an average satisfaction level of 97,33% and include in the very satisfied category. Statistical test of respondent characteristics such as gender, education, occupatient, patient age did not age affect the level of satisfaction of outpatients BPJS health participants to pharmacy services at the pharmacy installation of Efarina Etaham Hospital Pematangsiantar City.
EVALUASI PENGGUNAAN OBAT TUKAK LAMBUNG PADA PASIEN RAWAT JALAN DI RUMAH SAKIT EFARINA ETAHAM KOTA PEMATANGSIANTAR PERIODE JANUARI-MARET TAHUN 2024 Emi Sugesti; Meyana Marbun; Hekdin Marsius Sipayung; Devi Yuliani Luming
ZAHRA: JOURNAL OF HEALTH AND MEDICAL RESEARCH Vol. 4 No. 4 (2024): OKTOBER
Publisher : CV. ADIBA ADISHA AMIRA

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Abstract

Gastric ulcers are a condition where there is injury to the esophageal area, the lining of the stomach or duodenum caused by Helicobacteri pylori bacteria. Gastric ulcers can be caused by several factors, namely smoking, fast food, alcoholic drinks, NSAIDs and Helicobacteri pylori.The aim of this research is to determine the characteristics of the drugs used and the rationale for drug use in gastric ulcer patients. This research uses a descriptive method with a research design where data collection is carried out retrospectively, namely by searching the treatment records of gastric ulcer patients contained in prescription data or records. medical in the outpatient installation of Efarina Etaham Hospital, Pematangsiantar City for the period January-March 2024.he sample used was 75 prescriptions that met the inclusion criteria, based on research results, the types of drugs used for gastric ulcer patients were Lansoprazole 74.6%, Omeprazole 14.6%, Sucralfate 46.6%, Domperidone 20%, Antacids 1.3 %. The results of the rationality evaluation obtained 100% correct patient, 100% correct drug dose, 100% correct indication, 100% correct drug selection, 100% correct duration of administration. Overall, treatment that meets the 5 rationalities of rational treatment is 100%.
TINGKAT KEPATUHAN PENGGUNAAN OBAT ANTIDIABETES ORAL PADA PASIEN RAWAT JALAN DI UPTD PUSKESMAS TOMUAN KOTA PEMATANGSIANTAR TAHUN 2024 Emi Sugesti; Meyana Marbun; Octavian Ashindo Nababan; Afriyanti Sihombing
ZAHRA: JOURNAL OF HEALTH AND MEDICAL RESEARCH Vol. 4 No. 4 (2024): OKTOBER
Publisher : CV. ADIBA ADISHA AMIRA

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Abstract

The purpose of this study was to find out the description the level of adherence oral antidiabetic drug use in patiens outpatient treatment in UPTD Health center Tomuan City Pematangsiantar. The type of research used is an observational study using descriptive method.A total sampling technique is used with an amount 80 patients. The primary data collection instumen using Morisky Medication Adherence Scale 8 items (MMAS-8) questionnaire to see compliance rate of diabetes mellitus patient. The result of the study found that the level of adherence in using oral antidiabetic drugs in patients with in UPTD Tomuan health center Tomuan City Pematangsiantar said to be Low Compliance 47.5%, which was said to be Medium Compliance 27.5% Medium Compliance, which was said to be High Compliance 25%. Because many patients forgot to take their medicine yesterday and when the patient left the house the patient also forgot to take the medicine. Thus, it can be said that more patients with a level of compliance with the use of oral antidiabetic drugs are categorized as "Low Compliance" compared to patients with a Medium Compliance level and patients with a High Compliance level.
EVALUASI PENGGUNAAN OBAT ANTIHIPERTENSI PADA PASIEN RAWAT JALAN DI RUMAH SAKIT EFARINA ETAHAM KOTA PEMATANGSIANTAR PERIODE APRIL - JUNI TAHUN 2024 Wilson Samosir; Meyana Marbun; Hekdin Marsius Sipayung; Jesita Pratiwi Siagian
ZAHRA: JOURNAL OF HEALTH AND MEDICAL RESEARCH Vol. 4 No. 4 (2024): OKTOBER
Publisher : CV. ADIBA ADISHA AMIRA

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Abstract

Hypertension is an increase in systolic blood pressure of more than equal to 140 mmHg and diastolic blood pressure of more than equal to 90 mmHg (Ministry of Health, 2021). Data from the World Health Organization (WHO) states that hypertension is one of the causes of premature death throughout the world. By 2020 around 1.56 billion adults will be living with hypertension. The World Health Organization (WHO) notes that currently the global prevalence of hypertension is 22% of the world's total population. This study aims to broadcast the use of hypertension medication in patients at the Efarina Etaham Hospital, Pematangsiantar City for the period April-June 2024. Based on five indicators, namely the right indication, the right patient, the right drug, the right dose, the right duration of drug administration. create systematic, factual and accurate descriptions of images, or paintings regarding the facts, characteristics and relationships between the phenomena being marketed (Savira & Suharsono, 2019). This research was conducted on 80 medical records with a diagnosis of hypertension with or without comorbidities who received antihypertensive medication for the period April-June 2024. The results of the study showed that the appropriate evaluation of the use of antihypertensive medication was obtained, namely 100% correct indication, 100% correct patient, 100% correct medication. of 100% and the correct dose is 100%.
BAGAIMANA GAMBARAN PENGGUNAAN ANTIBIOTIK PADA INFEKSI SALUARAN PERNAFASAN AKUT (ISPA) TERHADAP PASIEN RAWAT JALAN DI RUMAH SAKIT TK IV 01.07.01 PEMATANGSIANTAR PERIODE JANUARI-MARET TAHUN 2024 Ismi Noer Farida; Meyana Marbun; Diyah Ayu Anggriani; Tri Sanjaya
ZAHRA: JOURNAL OF HEALTH AND MEDICAL RESEARCH Vol. 4 No. 4 (2024): OKTOBER
Publisher : CV. ADIBA ADISHA AMIRA

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Abstract

What is the description of use of antibiotics in acute respiratory infections (ARI) in outpatients at TK IV Hospital 01.07.01 Pematangsiantar for the period January-March 2024. Introduction;ISPA is a respiratory disease that attacks the upper respiratory and lower respiratory tract,starting from the nose to the lung sacs (alveoli). Method: descriptive research using a retrospective method carried out on past data, namely through medical records of adult ISPA patients. Results; This study shows the percentage results based on gender, the highest number of sufferers is 49 patients (51.04) female with the largest number of women with pneumonia, Namely as many as 28 ISPA patients (29.16 %) 29 use of antibiotics in ISPA patients due to administration of antibiotics.937 levofloxacin were freguently used amoxicillin 16 (66%) azhitromycin 36 patients (36.04 %) (amoxicillin),enterpenemav 17 (17.50) and 18 patients. The conclusion is that more female patients than men are affected by ISPA .the most common ISPA disease is pneumonia, starting at the age of 17-45 years. 500 patients (37.5%) use azitromiycine.