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All Journal Excellent Midwifery Journal ZAHRA: JOURNAL OF HEALTH AND MEDICAL RESEARCH International Conference on Health Science, Green Economics, Educational Review and Technology (IHERT) Medic Nutricia : Jurnal Ilmu Kesehatan Jurnal Pengabdian Bukit Pengharapan JFARM (Jurnal Farmasi)
Meyana Marbun
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Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary Other

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ANTI-INFLAMMATORY EFFECT OF LEAF ETHANOL EXTRACT OF CAT'S KUMIZE (Orthosiphon stamineus Benth) IN MALE WHITE RATS OF WISTAR STRAINS Meyana Marbun; Dian Permata Nasution; Beta Hanindiya; Mustaruddin; Yulia Delfahedah; Arsiaty
International Conference on Health Science, Green Economics, Educational Review and Technology Vol. 3 (2021): International Conference on Health Science, Green Economics, Educational Review and T
Publisher : Universitas Efarina

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54443/ihert.v3i.244

Abstract

The cat's whiskers plant is empirically used by the community for the treatment of gout and rheumatism. This research was conducted with the aim of knowing the anti-inflammatory power of cat's kumis (Orthosihon stamineus Benth) leaf extract. This study was a quasi-experimental study with a one-way completely randomized design. Kumis Kucing leaf extract was extracted using 70% ethanol. A total of 25 male wistar rats aged 2-3 months, weighing 150-200g were divided into 5 groups. Each group was treated orally with distilled water (negative control), diclofenac sodium 2.25 mg/kg BW (positive control). Kumis leaf ethanol extract tested at doses of 123, 245 and 490 mg/kgBB. Treatment 1 hour before the feet of rats were inflamed with 1% sublantar carrageenin. Measurements of the rat's foot volume were carried out every 0.5 hours for 6.5 hours. The obtained average edema volume curve is used to calculate AUC (Area Under The Curve) and the obtained AUC is used to calculate DAI (Anti-Inflammatory Power). The AUC and DAI data were tested statistically with one way Anava and followed by LSD with a 95% confidence level. The results showed that the ethanol extract of Kumis Kucing leaves had an anti-inflammatory effect on male white rats of the Wistar strain. Kumis Kucing ethanol extract at doses of 123, 245 and 490 mg/kg BW yielded 33.11%; 52.64% and 64.12% respectively. The results showed that the ethanol extract of Kumis Kucing leaves had an anti-inflammatory effect on male white rats of the Wistar strain. Kumis Kucing ethanol extract at doses of 123, 245 and 490 mg/kg BW yielded percent anti-inflammatory properties of 33.11%; 52.64% and 64.12%, respectively. The results showed that the ethanol extract of Kumis Kucing leaves had an anti-inflammatory effect on male white rats of the Wistar strain. Kumis Kucing ethanol extract at doses of 123, 245 and 490 mg/kg BW yielded percent anti-inflammatory properties of 33.11%; 52.64% and 64.12%, respectively.
UTILIZATION OF TURMERIC RHIZOME EXTRACT (Curcuma domestica v.) AS A DYE IN HAIR DYE PREPARATIONS Meyana Marbun; Arsiaty Sumule; Yulia Delfahedah; Muharti Sanjaya; Dilla Sastia Mara
International Conference on Health Science, Green Economics, Educational Review and Technology Vol. 4 (2022): International Conference on Health Science, Green Economics, Educational Review and T
Publisher : Universitas Efarina

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54443/ihert.v4i.246

Abstract

Hair coloring preparations are cosmetic preparations used in hair cosmetology to color hair, either to restore the original hair color or another color. Turmeric rhizome contains alkaloids, flavanoid tannins and essential oils. The purpose of this study was to determine the chemical compounds contained in turmeric rhizome, to make turmeric rhizome change the color of gray hair. Hair dye preparation is made with a formula consisting of a concentration of turmeric extract rhizome, namely 20%. This research method is experimental by using maceration method. Physical evaluation carried out included homogeneity test, irritation test, color stability test against sun exposure, color stability test against washing. The results of this study indicate that turmeric rhizome extract can affect the color of the gray hair obtained. The stability test against washing can last for 5 times washing, the stability test against sunlight shows that the hair turns darker than before.
Co-Authors Afriyanti Sihombing Amanda Sahfitri Arsiaty Arsiaty Sumule Beta Hanindiya Boas Nicoyono Pasaribu Devi Yuliani Luming Dian Permata Nasution Dilla Sastia Mara Dilla Sastri Mara Diyah Ayu Anggriani Emi Sugesti Hekdin Marsius Sipayung Indri Nurhabibah Ismi Noer Farida Jesita Pratiwi Siagian Juliana Siboro Jumadiah Wardati Keysha Iszmi Erhan Marolop. P. Napitu Muharti Sanjaya Mustaruddin Octavian Ashindo Nababan Romauli Sihaloho Toberni S. Situmorang Tri Sanjaya Ummi Umayyah Wilson Samosir Yulia Delfahedah Yunda Pita Sari Simbolon Zendrato, Ferawati