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All Journal Narra J Heca Journal of Applied Sciences Malacca Pharmaceutics Journal of Educational Management and Learning Grimsa Journal of Science Engineering and Technology Journal Of Carbazon
Kemala, Pati
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Earth & Planetary Sciences Education Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health Other

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Sustainable Plant-Assisted Production of Silver Nanoparticle Hybrids for Antimicrobial Use: Insights from Chromolaena odorata and Patchouli Oil Pebriani, Liska Nova; Kemala, Pati; Idroes, Ghazi Mauer; Fatriasari, Widya; Khairan, Khairan; Idroes, Rinaldi
Grimsa Journal of Science Engineering and Technology Vol. 4 No. 1 (2026): April 2026
Publisher : Graha Primera Saintifika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61975/gjset.v4i1.117

Abstract

This study developed a green synthesis approach for silver nanoparticles (AgNPs) using ethanolic extracts of Chromolaena odorata leaves (LCo) collected from geothermal areas, followed by post-synthesis incorporation of patchouli oil (PO) to improve antimicrobial performance. The synthesis was optimized using Response Surface Methodology (RSM) based on AgNO₃ concentration and pH, with surface plasmon resonance (SPR) as the response indicator. Successful formation of AgNPs was confirmed by characteristic SPR absorption in the visible region. Structural and morphological analyses indicated the involvement of plant-derived functional groups in nanoparticle stabilization, with predominantly spherical particles and some aggregation observed. Antimicrobial testing against Staphylococcus aureus, Escherichia coli, and Candida albicans showed that the PO-AgNPs-LCo system exhibited a slightly higher inhibition zone compared to AgNPs-LCo alone, indicating a marginal enhancement in antimicrobial activity. These results suggest that geothermal-derived plant extracts can be effectively utilized for AgNPs synthesis, while post-synthesis incorporation of natural oils may provide additional functional modification. However, the observed enhancement remains limited, indicating the need for further optimization and mechanistic studies. Overall, this work highlights a simple and eco-friendly route for developing plant-based antimicrobial nanomaterials.
Co-Authors - Fakhrurrazi Abas, Abdul Hawil Ahmad, Khairunnas Asep Rusyana Astryna, Syarifah Yanti Bachtiar, Boy Muhclis Binawati Ginting Boy M. Bachtiar Celik, Ismail Destiana, Khaerunisa Diana Setya Ningsih, Diana Diana Setya Ningsih, Diana Setya El-Shazly, Mohamed Ghazi Mauer Idroes Hakim, Rachmi F. Hanafiah, Olivia A. Harera, Cheariva Firsa Hizir Sofyan Idroes, Ghazi M. Idroes, Ghifari Maulana Isnaini, Nadia Khairan Khairan Lubis, Vanizra F. Maghfirah, Ruhul Maulana, Aga Maulydia, Nur B. Maulydia, Nur Balqis Maysarah, Hilda Mirda, Erisna Muliadi Ramli Muslem Muslem, Muslem Ningsih, Diana S. Noviandy, Teuku R. Patwekar, Mohsina Pebriani, Liska Nova Putra, Noviandi I. Rahman, Sunarti Abd Rinaldi Idroes Romadhoni, Yenni Salsabila, Indah Sasmita, Novi Reandy Shafira, Ghina A. Trina E. Tallei, Trina E. TRINA EKAWATI TALLEI Widya FATRIASARI Zuchra Helwani, Zuchra