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All Journal Jurnal Farmasi Klinik Indonesia Pharmacology and Clinical Pharmacy Research
Puspita, Falerina
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Medicine & Pharmacology

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Evaluation of Antibiotic Use in Pediatric Inpatients at one of Bandung Regional Hospitals in August 2023 Maharani, Putri; Wicaksono, Imam A.; Puspita, Falerina; Zainudin, Hijrah M.
Pharmacology and Clinical Pharmacy Research Vol 9, No 1 (2024)
Publisher : Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15416/pcpr.v9i1.52984

Abstract

Infectious diseases are a major concern in the field of health, especially in developing countries like Indonesia. Children are vulnerable to infections because their immune systems are not fully developed. Proper management is necessary for the prevention and treatment of infectious diseases in pediatric patients. Antibiotics are the primary choice for addressing bacterial infections. However, the increased use of antibiotic can contribute to high levels of antimicrobial resistance (AMR), rendering infection treatment ineffective. The evaluation of antibiotic use can be conducted through the ATC/DDD method, which focuses on the quantity and types of antibiotics used. Although this method provides a quantitative overview, a qualitative approach using the Gyssens method and interviews with relevant parties is necessary for a more in-depth understanding of the rationality of antibiotic use. This study aims to comprehend the patterns of antibiotic use in pediatric inpatients at one of Bandung Regional Hospitals during August 2023. Using a retrospective observational approach, data were collected and processed using the ATC/DDD method. The evaluation results show that cephalosporins is the most commonly used antibiotic group, with cefotaxime being the dominant antibiotic administered intravenously. Quantitative evaluation indicates variations in DDD/100 patient days among different antibiotics, with ciprofloxacin having the highest value and amikacin the lowest. For a comprehensive understanding, qualitative research using the Gyssens method and interviews is necessary to strengthen the evaluation results of antibiotic use. Ultimately, this study provides a thorough perspective on antibiotic use in pediatric inpatients, supporting efforts to control antimicrobial resistance and promote more judicious antibiotic selection.
Evaluasi Penggunaan Antibiotik Profilaksis pada Pasien Bedah Obstetri dan Ginekologi di Salah Satu Rumah Sakit Kota Bandung pada Bulan September 2023 Rahmadinna, Salsabila; Wicaksono, Imam Adi; Puspita, Falerina; Zainuddin, Hijrah Mutaqin
Indonesian Journal of Clinical Pharmacy Vol 12, No 3 (2023)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15416/ijcp.2023.12.3.54972

Abstract

Antibiotik profilaksis adalah antibiotik yang diberikan pada pasien sebelum pembedahan untuk mencegah infeksi pascaoperasi. Penelitian ini bertujuan mengevaluasi penggunaan antibiotik profilaksis pada pasien bedah obstetri-ginekologi di salah satu rumah sakit Kota Bandung. Penelitian deskriptif noneksperimental ini menggunakan data retrospektif dari 200 pasien periode September 2023. Data yang telah terkumpul diolah dengan menghitung persentase pola penggunaan antibiotik dan parameterparameter yang meliputi jenis antibiotik yang digunakan, bentuk sediaan, dosis, rute pemberian dan waktu pemberian antibiotik. Hasil penelitian menunjukkan kesesuaian penggunaan jenis antibiotik profilaksis yaitu cefazolin sebesar 8,5%, kesesuaian bentuk sediaan dalam vial sebesar 100%, kesesuaian dosis yang digunakan sebanyak 2 gram sebesar 7%, kesesuaian rute pemberian antibiotik profilaksis yaitu melalui intravena kesesuaian sebesar 100%, kesesuaian waktu pemberian antibiotik 30–60 menit sebelum insisi kulit sebesar 68%. Implikasi klinisnya menunjukkan bahwa rendahnya kesesuaian dapat meningkatkan risiko infeksi pascaoperasi dan resistensi antibiotik, yang berdampak pada perburukan hasil klinis pasien dan biaya perawatan. Oleh karena itu, diperlukan intervensi berbasis edukasi dan pelatihan untuk meningkatkan kepatuhan tenaga medis terhadap pedoman penggunaan antibiotik profilaksis, sehingga dapat mendukung pencegahan komplikasi dan peningkatan kualitas pelayanan. Disimpulkan bahwa evaluasi penggunaan antibiotik di rumah sakit ini masih belum sesuai pedoman Permenkes RI No. 28 Tahun 2021.
Co-Authors IMAM ADI WICAKSONO, IMAM ADI Putri Maharani Rahmadinna, Salsabila Wicaksono, Imam A. Zainuddin, Hijrah Mutaqin Zainudin, Hijrah M.