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All Journal Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Pena Medika : Jurnal Kesehatan Journal of Pharmaceutical and Health Research Jurnal Buana Farma Journal of Social Responsibility Projects by Higher Education Forum Kolaborasi Jurnal Pengabdian Masyarakat Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Pharmacy Genius Journal of Pharmaceutical and Sciences.
Kurniasih, Khamdiyah Indah
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Pemanfaatan Tanaman Obat Keluarga (TOGA): Pelatihan Pembuatan Teh Herbal Bagi Ibu-ibu PKK Rahmawati, Nur; Fauziah, Fauziah; Kurniasih, Khamdiyah Indah; Kirana, Ade
Journal of Social Responsibility Projects by Higher Education Forum Vol 4 No 3 (2024): Maret 2024
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jrespro.v4i3.5013

Abstract

The term Family Medicinal Plants (TOGA) has become more popular in the last decade or so. Before this, family medicinal plants were better known as Living Pharmacy. Family medicinal plants have long been utilized in an effort to overcome health problems. Therefore, the utilization of TOGA needs to be developed and disseminated in the community, especially for housewives. Among the many family medicinal plants used by the community to maintain health is bay leaf. The utilization of bay leaves is processed as a healthy drink innovation, herbal tea in the form of tea bags because it is more practical and easy to make. Bay leaf herbal tea can be used to prevent cancer, lower cholesterol, increase the body's immune system, reduce the risk of kidney stones, maintain blood sugar levels and overcome stomach pain. The main target of this service is one of the PKK women's groups in Karangnanas Village, Banyumas Regency. who work as housewives. The purpose of this activity is to increase community understanding about traditional drinks from bay leaves that can reduce cholesterol. The results of this herbal tea making training activity increase good information to the community and can manage traditional beverage products made from bay leaves. With bay leaves being one of the alternative natural ingredients that can be utilized as traditional medicine to help treat diseases such as cholesterol, hypertension, gout, diabetes mellitus.
Analisis penggunaan antidiabetik dan antihipertensi pada pasien diabetes komorbid hipertensi di Puskesmas Mrebet Melani, Reina; Kurniasih, Khamdiyah Indah; Fauziah, Fauziah
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.382

Abstract

Diabetes Mellitus (DM) is a chronic disease characterised by high blood sugar levels. Diabetes mellitus is considered the "mother disease" because it is the mother of various diseases such as hypertension, heart disease, stroke, kidney failure and blindness. There were 13,117 DM cases in Purbalingga Regency, and 14,035 people were provided services according to procedures. Increased blood glucose levels (hyperglycemia) cause intravascular fluid resistance, which results in an increase in body fluid volume and an increase in peripheral arterial resistance. These two conditions are the basis for hypertension. There is a need for appropriate antidiabetic therapy to treat hypertension comorbid DM disorders. This research was conducted at the Mrebet Community Health Center, Purbalingga Regency, where the results obtained were 55 data on the use of prolanis medication for DM comorbid hypertension patients. In this study, the most common single therapy was metformin (12.7%), then the two most common combinations were glimepiride and acarbose (41.8%), while the three combinations used were metformin, glimepiride and acarbose (12.7%). The most common single antihypertensive was Lisinopril (28.2%), and the most common combination was Lisinopril + Amlodipine (28.2%).
Potensi hepatoprotektif ekstrak daun Euphorbia heterophylla L. dalam menurunkan kadar bilirubin pada tikus Wistar yang diinduksi INH dan rifampisin Kurniasih, Khamdiyah Indah; Fauziah, Fauziah; Ratna, Uki Septi
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.592

Abstract

Hepatitis is a liver damage disorder characterized by inflammation caused by various factors, one of which is medication use. Liver damage due to medication, or drug-induced liver injury (DILI), has a relatively high prevalence. Isoniazid (INH) + Rifampicin is a combination of drugs that poses a risk of DILI by causing liver damage. One parameter for assessing liver damage is through the measurement of total serum bilirubin levels. Katemas herb (Euphorbia heterophylla L) is a plant known to contain flavonoids, tannins, and saponins, with strong antioxidant properties. The high incidence of liver damage due to drug-induced liver injury (DILI) necessitates the exploration of alternative therapies to manage liver disorders. Katemas is a wild grass that grows abundantly but remains underutilized.The objective of this study is to evaluate the hepatoprotective activity of katemas herb leaves. The method used in this research involves maceration to obtain extracts, with ethanol 96% as the solvent. Testing was conducted on five groups of rats, with total serum bilirubin levels measured across all groups. All groups were induced using INH and RMP. The results showed that Groups III and IV, which were the dose variation groups, exhibited hepatoprotective activity. Group V, which received the highest dose of 200 mg/kg BW, demonstrated the greatest reduction in total bilirubin levels, with the largest mean decrease (-0.226) and a small standard deviation (±0.043).
PENGARUH KONSENTRASI EKSTRAK WORTEL (Daucus carota L.) DALAM FORMULASI LOTION TERHADAP EFEKTIVITAS PENCERAHAN KULIT Fitri, Ely Nurul; Nawangsari, Desy; Kurniasih, Khamdiyah Indah
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1527

Abstract

Carrot (Daucus carota L.) is a natural source rich in β-carotene, an antioxidant compound that may inhibit melanin formation through the tyrosinase inhibition mechanism. This study aimed to determine the effect of varying concentrations of carrot extract in lotion formulations on skin-brightening effectiveness. This experimental laboratory study used four lotion formulations: a negative control, Formula 1 (5%), Formula 2 (10%), Formula 3 (15%), and a positive control (Kojie San® commercial lotion). The formulations were evaluated for physical characteristics (organoleptic, homogeneity, pH, spreadability, adhesion, and viscosity), safety through skin irritation testing, and skin-brightening effectiveness using a human skin tone set for 14 days on 25 female respondents. The results showed that all formulations met the physical property parameters, except for spreadability and adhesion, which were below the standard. No skin irritation was observed. Based on the skin-brightening test, 16% of respondents showed an improvement in skin brightness after 14 days of application, with Formula 3 (15%) exhibiting the highest effect, where 8% of respondents experienced a one-level increase on the skin tone scale compared to other formulations and the negative control. It can be concluded that the variation in carrot extract concentration affected the skin-brightening effectiveness, with the 15% formulation showing the highest result. These findings indicate that β-carotene in carrot extract has potential as a safe and effective natural active ingredient in cosmetic skin-lightening formulations.
Co-Authors Abely, Nastasya Anis Ardhana, I Putu Primanda Dodi Fauziah Fauziah , Fauziah Fauziah Fauziah Fitri, Ely Nurul Ikhwan Yuda Kusuma Kirana, Ade Lukman Hakim Melani, Reina Misworo, Misworo nawangsari, desi Nawangsari, Desy Nur Rahmawati Nurkholis, Fiqih Prabandari, Rani Prismadito, Hansen Putri, Arine Astika Ratna, Uki Septi Safitri, Cindy Ade Samodra, Galih Setyaningsih, Intan Wiji Siti Setianingsih Ulinnuha, Alvin