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Formulation and Evaluation of Gel Mask Peel Off Moringa Leaf Extract (Moringa oleifera Lam) Santi Agustina; Anna L Yusuf; Davit Nugraha
Ad-Dawaa : Journal of Pharmacy Vol. 1 No. 1 (2023): Ad-Dawaa: Journal of Pharmacy (May 2023)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v1i1.224

Abstract

Peel-off gel mask is a practical mask, after drying the mask can be directly removed or removed without causing pain. This mask can also restore freshness and softness of the skin, even with regular use it can reduce fine wrinkles on facial skin. Moringa plants contain antioxidants, especially the leaves that contain flavonoids, causing Moringa leaves to be used as a source of natural antioxidants. The research method used is an experimental method with peel off gel mask preparation samples of Moringa leaf extract with various concentrations of 0% (F0), 5%(F1), 10%(F2), and15% (F3). Data analysis using One Way Anova test with 95% confidence level of significance = 0.05. Evaluation of the peel off gel mask preparation includes organoleptic test, homogeneity test, pH test, viscosity test, dispersibility test, adhesion test, dry time test and syneresis test. The results of the research F0, F1, F2 and F3 met the standard of the tests carried out such as organoleptic tests, pH tests, dispersibility tests, adhesion tests, dry time tests, and syneresis tests. The results of the One Way Anova statistical test for the pH test obtained a P-Value value of 0.63> 0.05, the dispersion test obtained a P-Value value of 0.02 0.05, the drying time test obtained a P-Value value of 0.00 (0.05) while the test dispersion and syneresis test there is an effect of giving concentration variations with a significance value of P < (0.05).
Formulation and Evaluation of Avocado Leaf Extract (Persea americana Mill.) Cream Based on Variations Stearic Acid Concentration Bahariyan Ramdhan; Anna L Yusuf
Ad-Dawaa : Journal of Pharmacy Vol. 1 No. 2 (2023): Ad-Dawaa: Journal of Pharmacy (November 2023)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v1i2.412

Abstract

Avocado leaves (Persea americana Mill.) contain flavonoid compounds as high as 8.11 mg, so they have potential in the acne healing process. The aim of this research is to create a formulation and evaluate an avocado leaf extract cream preparation. The method used is experimental. Avocado leaf extract cream preparations are made based on varying stearic acid concentrations of 5%, 10% and 15%. Evaluation of the preparation includes organoleptic tests, homogeneity tests, pH tests, spreadability tests, adhesion tests, and viscosity tests. Based on the organoleptic evaluation, the results showed that FI was slightly runny and contained bubbles, FII was slightly thick and FIII was thick. The FI color is brownish white, FII is yellowish white, and FIII is white, and all formulations have a characteristic creamy odor. The homogeneity test shows that all formulas have the same homogeneous preparation. The pH test of the cream preparation showed the same pH value, namely 6. The spreadability test resulted in good spreadability of the cream, namely between 5 and 6.8 cm. The cream adhesion test has an adhesion between 00.53 and 1.38 seconds. And finally, the viscosity test has a viscosity value between 4500 and 8900 mpa. According to the results of this research, avocado leaf extract cream can be used as a cream preparation, with the best stearic acid concentration being 15%.
Narrative Review: Optimation of Ethanol as a Solvent for Flavonoid Compounds in Papaya Leaf Extraction Davit Nugraha; Anna L Yusuf; Panji Wahlanto
Ad-Dawaa : Journal of Pharmacy Vol. 1 No. 2 (2023): Ad-Dawaa: Journal of Pharmacy (November 2023)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v1i2.496

Abstract

Ethanol is widely used as a distiller of secondary metabolite compounds. Ethanol very well dissolves secondary metabolite compounds including flavonoids group compounds including for papaya (Carica papaya L.) leaf extraction. This review was conducted to examine solvent optimization that has been used in various original studies. The method of searching scientific journal article using PubMed and MDPI using keyword “extraction and ethanol and flavonoid and carica papaya leaf” with the inclusion criteria of 2018 – 2023 article, free full text and not review articles, the number of article obtained was 3 articles. The optimal concentration of ethanol as a flavonoid extract solven is 70 % ethanol at temperatures from 30 °C – 50°C with a time range of 10 – 48 hours of immersion.
Pemberdayaan Ketahanan Pangan pada Stunting di Desa Buana Mekar Kecamatan Panumbangan Kabupaten Ciamis Elis Roslianti; Siti Rahmah Kurnia Ramdan; Anna L Yusuf; Ade Raina
Daarul Ilmi: Jurnal Pengabdian Kepada Masyarakat Vol. 1 No. 2 (2023): Daarul Ilmi: Jurnal Pengabdian Kepada Masyarakat (Juli-Desember 2023)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/daipkm.v1i2.391

Abstract

Introduction: Stunting is a condition where a child experiences growth disorders, so that the child's height and weight do not match his age. This is caused by a lack of nutritional intake for a long time. Indonesia is a country with multiple nutritional problems, characterized by a high prevalence of stunting and anemia in pregnant women. Objective: The aim here is that it is hoped that stunting cases that exist, especially in the Buana Mekar Village area, can be prevented. In this way, children can grow and develop well so that an intelligent and healthy young generation is created. Method: The community service method is carried out through counseling and discussions with female cadres at the Buana Mekar Village Hall, Ciamis Regency. Result: Based on counseling activities, it can be concluded that 16 people (40%) of the participants were able to answer questions before the implementation of health education, before the material was delivered, there were 24 people (60%) who did not answer questions. And after the presentation was delivered, the participants' knowledge increased 100%. So it can be concluded that the participants present quite understand the material presented. Conclusion: The conclusion of the implementation of health counseling activities regarding the handling of stunting went well in accordance with what was expected and planned. This health education is effective and has positive values for the counseling participants. This can be seen from the enthusiasm and activeness of these health education participants and the increasing knowledge about handling resistance to stunting before and after education is given.
Penyuluhan Tentang Pemanfaatan Sambiloto (Andrgraphis paniculata) Untuk Mencegah dan Mengobati Penyakit Hipertensi Siti Rahmah Kurnia Ramdan; Marlina Indriastuti; Anna L Yusuf; Davit Nugraha; Panji Wahlanto
Daarul Ilmi: Jurnal Pengabdian Kepada Masyarakat Vol. 2 No. 1 (2024): Daarul Ilmi: Jurnal Pengabdian Kepada Masyarakat (Januari-Juni 2024)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/daipkm.v2i1.564

Abstract

Introduction: Hypertension is one of the factors causing cardiovascular disease and is the main cause of death in the world. Hypertension can be influenced by various factors, including genetic factors and an unhealthy lifestyle. Preventing and treating hypertension is very important in order to reduce risk factors for death. Prevention and treatment of hypertension with traditional medicine or herbal medicine is an alternative that is currently in great demand and attention because it has minimal side effects and is quite effective. Andrographis paniculata is a medicinal plant that has been widely studied and is effective in preventing and treating hypertension. The main content of this plant is andrographolidine which is a phytochemical substance which has many benefits, including antihypertension. Objective: The aim of this outreach activity is to provide understanding to the public about the use of bitter (Androghraphis paniculata) to prevent and treat hypertension. Method: Education to the public about the use of Androghraphis paniculata is carried out through the lecture method. The material presented is an explanation of hypertension, the benefits of bitter as a medicinal plant, the benefits of bitter in preventing and treating hypertension and how to process it on a household scale. Explanation of how to process bitter for treatment, namely using the infusion method. Giving pre-tests and post-tests to counseling participants is carried out to evaluate the level of community understanding. Result: By providing education about the use of bitter to prevent and treat hypertension, it can increase public knowledge about hypertension, the causal factors, as well as the benefits of bitter and how to use it as a medicinal plant. Knowledge before and after counseling increased by 36.65%. The community is very enthusiastic in following the outreach that we do. Conclusion: With the outreach, participants know more about hypertension and the use of bitter in preventing and treating hypertension and how to process it. Participants' knowledge increased by 36.65%.
AKTIVITAS ANTIBAKTERI AIR PERASAN BUAH PEPAYA (Carica papaya L.) TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus: ANTIBACTERIAL ACTIVITIES OF PEPAYA JUICE (Carica papaya L.) ON THE GROWTH OF Staphylococcus aureus BACTERIA Davit Nugraha; Anna L. Yusuf; Veri Nugraha; Panji Wahlanto; Marlina Indriastuti
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 7 No 4 (2022)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v7i4.470

Abstract

Bakteri Staphylococus aureus merupakan bakteri patogen dan dapat menyebabkan infeksi mulai dari infeksi kulit ringan sampai dengan infeksi sistemik. Sebagian besar pada awal mulanya Staphylococus aureus peka terhadap penisilin, namun setelah meluasnya penggunaan penisilin ditemukan 65% sampai 85% Staphylococus aureus menghasilkan beta laktamase sehingga menjadi resisten terhadap penisilin G.  Hal tersebut diatas mendorong pengobatan alternatif yang aman dan tidak menimbulkan resistensi untuk menanggulangi infeksi bakteri Staphylococus aureus.  Perasan buah pepaya sering terdengar penggunaan dimasyarakat untuk pengobatan jerawat secara turun temurun, ini dimungkinkan perasan buah pepaya mempunyai efek anti bakteri Staphylococcus aureus. Penelitian ini bertujuan untuk mengetahui kemampuan daya hambat air perasan buah papaya (Carica Papaya L) terhadap bakteri Staphylococcus aureus. Metode pengujian daya hambat pada air perasan buah papaya menggunakan metode difusi agar dengan konsentrasi 20%, 40%, 60% dan 80%. Air perasan buah pepaya pada penelitian ini mempunyai kemampuan daya hambat yang sedang terhadap pertumbuhan bakteri Staphylococcus aureus, serta konsentrasi yang paling efektif sebesar 60%.
VARIASI FORMULA SEDIAAN FACEMIST EKSTRAK ETANOL DAUN KELOR (Moringa oleifera L.) DAN PENGARUHNYA PADA PENINGKATAN KELEMBABAN WAJAH : FACEMIST ETHANOL EXTRACT OF MORINGA LEAVES (Moringa oleifera L.) FORMULA VARIATIONS AND EFFECTS ON FACIAL MOISTURE IMPROVEMENT Marlina Indriastuti; Nurhidayati Harun; Oktapiana Rismaya; Nia Kurniasih; Anna L Yusuf; David Nugraha
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 1 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i1.655

Abstract

Facemist adalah produk perawatan kulit wajah berbentuk spray yang diformulasikan untuk membuat kulit lebih segar,  lembab dan dapat digunakan untuk mencegah paparan radikal bebas dari polusi udara. Facemist termasuk salah satu kosmetika yang digunakan untuk merawat dan mempertahankan kondisi kulit wajah. Produk bahan alam untuk perawatan kulit semakin meningkat permintaannya saat ini. Salah satu antioksidan alami terdapat pada daun kelor (Moringa oleifera L.) yang bekerja dengan cara menangkap radikal bebas. Penelitian eksperimental dilakukan dengan memformulasi ekstrak etanol daun kelor menjadi sediaan facemist, uji kelembaban pada kulit wajah baik normal maupun kering dan dilakukan uji cemaran mikrobanya. Variasi formula ekstrak daun kelor yang dibuat 3%, 7%, dan 10%, dari hasil evaluasi sediaan formula terbaik adalah formula D dengan uji cemaran mikroba 2,6 x 102  CFU/ml yang memenuhi standar evaluasi mutu dimana untuk cemaran mikroba tidak boleh lebih dari 103 CFU/ml. Hasil dari penelitian menunjukkan, uji kelembaban facemist pada kulit normal yaitu formula A sebesar 11.76%, B sebesar 12.50%, C sebesar 16.37% dan D sebesar 38.45%. Persen tingkat kelembaban pada kulit kering yaitu formula A sebesar 26.67%, B sebesar 27.00%, C sebesar 28.24% dan D sebesar 30.54%. Maka dapat disimpulkan, formula terbaik adalah formula D dengan hasil uji  kelembaban pada kulit normal 38,45% dan pada kulit kering 30.54% dengan uji cemaran mikroba yang memenuhi persyaratan mutu.
OPTIMASI FORMULA SEDIAAN GRANUL EFFERVESCENT EKSTRAK DAUN KELOR (Moringa oleifera L.): FORMULA OPTIMIZATION OF EFFERVESCENT GRANULE OF MORINGA LEAF EXTRACT (Moringa Oleifera L.) Marlina Indriastuti; Ayu Fuji Astuti; Anna L Yusuf; Faisal Akbar; Rahmah Kurnia R
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 3 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i3.760

Abstract

Daun tanaman kelor (Moringa oleifera L.) sering dimanfaatkan oleh masyarakat sebagai tanaman obat tradisional yang memiliki kandungan antioksidan. Penelitian yang dilakukan bertujuan untuk mengembangkan formulasi, memperbaiki rasa, dan mengevaluasi granul effervescent ekstrak daun kelor (Moringa oleifera L.) menggunakan perbedaan variasi konsentrasi sorbitol dengan metode granulasi basah. Evaluasi granul effervescent meliputi uji organoleptik, uji kadar air, uji daya alir, uji sudut diam, uji waktu dispersi, uji pH, dan uji ketinggian buih. Tiga formula yang berbeda divariasi dengan memilih konsentrasi sorbitol yang berbeda yaitu formula 1 dengan konsentrasi sorbitol 0,5%, formula 2 1%, dan formula 3 2%. Evaluasi sediaan menunjukkan formula terbaik adalah formula 3 dengan hasil uji evaluasi fisik formula 3 yaitu, berbentuk serbuk berwarna hijau dengan bau khas daun kelor, kadar air 1,93%, daya alir 7,41 g/s, sudut diam 28,07°, waktu dispersi 72 detik, pH 6,47, dan ketinggian buih 2,6 cm. Hasil dari evaluasi formula 3 dengan konsentrasi sorbitol tertinggi tersebut memenuhi persyaratan. Selain itu, formula 3 juga menghasilkan rasa effervescent yang paling baik, yaitu dengan rasa manis asam dengan sensasi segar. Kata kunci : kelor, granul effervescent, sorbitol, Moringa oleifera
HUBUNGAN PENGETAHUAN SWAMEDIKASI TERHADAP POLA PENGGUNAAN OBAT MASYARAKAT DI DUSUN SANAN PLERET BANTUL Astuti, Febriana; Apriyani, Herlinan Dwi; Capritasari, Rafiastiana; Azzahra, Faza; Yusuf, Anna Lesmanasari
Jurnal Kesehatan Bakti Tunas Husada: Jurnal Ilmu-ilmu Keperawatan, Analis Kesehatan dan Farmasi Vol 24, No 1 (2024)
Publisher : LPPM Universitas Bakti Tunas Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36465/jkbth.v24i1.1303

Abstract

Mengobati diri sendiri dengan obat tanpa resep yang tepat dan rasional dikenal dengan istilah swamedikasi (Pratiwi et al., 2018). Menurut Badan Pusat Statistik (BPS) pada tahun 2022 masyarakat Indonesia melakukan swamedikasi sebesar 84,34%. Dari 84,34% masyarakat indonesia presentase masyarakat yang melakukan swamedikasi, 82,55% diantaranya masyarakat yogyakarta (BPS,2022). Hasil studi pendahuluan di Dusun Sanan menunjukkan bahwa keterbatasan informasi dan tingkat pendidikan masyarakat yang rendah. Hal ini dapat menyebabkan masyarakat rentan terhadap informasi komersial tentang obat, yang dapat menyebabkan pengobatan yang tidak rasional jika tidak diberikan informasi yang benar. Studi ini bertujuan untuk mengidentifikasi hubungan antara tingkat pengetahuan tentang swamedikasi dan pola penggunaan obat masyarakat di Dusun Sanan, Kelurahan Bawuran, Kecamatan Pleret, Kabupaten Bantul. Penelitian korelasional    dengan    pendekatan    cross sectional ini, menggunakan teknik purposive sampling. Sebanyak 277 responden diminta untuk mengisi kuisioner, dan uji korelasi Rank Spearman digunakan untuk menganalisis data. Secara keseluruhan, hasil analisis deskriptif variabel menunjukkan bahwa pengetahuan tentang swamedikasi dan pola penggunaan obat adalah baik. Hasil frekuensi swamedikasi, tempat pembelian, jarak lokasi, harga obat, efek samping, dan sumber informasi memiliki hubungan dengan pengetahuan karena nilai signifikansi < 0,05. Sedangkan untuk nama obat, bentuk obat, dan keluhan ringan tidak memiliki hubungan dengan pengetahuan karena nilai signfikansi > 0,05.
Formulation and Evaluation of Peel-Off Gel Mask with Tomato Fruit Extract Using PVA Base Rahmi, Ai; Yusuf, Anna L
Ad-Dawaa : Journal of Pharmacy Vol. 2 No. 1 (2024): Ad-Dawaa: Journal of Pharmacy (May 2024)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v2i1.731

Abstract

Tomatoes have been widely used in society as a homemade mask by mashing them until smooth and then applying them to the face. Tomatoes have health and beauty benefits because they have high nutritional content such as antioxidants lycopene, vitamin C, potassium, folate and vitamin A. Using tomatoes as a mask has benefits for the skin because they have antioxidant activity so they can provide a brightening effect and can prevent aging. Peel-off gel masks are one of the masks that are practical to use, because after drying the mask can be removed immediately without rinsing. Peel-off gel masks are made with a Polyvinyl Alcohol (PVA) base as a gelling agent that has the ability to form a film layer so that it is easy to peel off after drying. Evaluation of the peel-off gel mask preparation consists of organoleptic tests, viscosity tests, pH tests, spreadability tests and drying time tests. From the results of organoleptic observations, the resulting preparation is a thick preparation with a distinctive tomato odor and has a brick red color. The evaluation results of the viscosity test, pH test, spreadability test and drying time test showed that the peel-off gel mask preparation met the requirements.